ANALYST
·
2024
·Vol. 149
·期 15
·4060-4071
·
IF 3.6
Jie Zhou,Huiting Wang,Yaxian Chen,Dongxue Lin,Ling Zhang,Zhiqiang Xing,Qian Zhang,Jiarui Xia
The precise quantitative analysis using surface-enhanced Raman spectroscopy (SERS) in an uncontrollable environment still faces a significant obstacle due to the poor reproducibility of Raman signals. Herein, we propose a facile method to fabricate a self-calibrating substrate based on a flexible polyvinyl alcohol (PVA) film comprising assemblies of Prussian blue (PB) and Au NPs (PB@Au) for reliable detection. PB cores were coated with an Au shell through simple electrostatic interaction, forming core–shell nanostructure PB@Au assemblies within the PVA film. The outer Au layer provided identical trends in enhancement for both the PB core and neighboring targets while PB cores served as an internal standard (IS) to correct signal fluctuations. The prevention of competitive adsorption on the metal surface between targets and ISs was achieved. The proposed PVA/PB@Au film exhibited enhanced stability of Raman signals after IS correction, resulting in improved spot-to-spot and batch-to-batch reproducibility with significantly reduced standard deviation (RSD) values from 11.42% and 25.02% to 4.43% and 9.39%, respectively. Simultaneously, a higher accuracy in the quantitative analysis of 4-mercaptobenzoic acid (4-MBA) and malachite green (MG) was achieved with fitting coefficient (R2) values improving from 0.9675 and 0.9418 to 0.9974 and 0.9832, respectively. Moreover, the PVA/PB@Au film was successfully applied to detect residual MG in real fish samples. This work opens up an avenue to improve the reproducibility of Raman signals for flexible SERS substrates in the detection of residues under various complex conditions.
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IEEE SENSORS JOURNAL
·
2024
·
IF 4.3
Song Xie,Haotian Wu,Xiaozhan Yang
A microfluidic electrochemical sensor is fabricated for the measurement of chemical oxygen demand (COD) in surface waters such as lakes and reservoirs. An Au interdigital electrode is used as a substrate, and a layer of Au nanoparticles (AuNPs) is deposited on the working electrode surface to form a functionalized working electrode. A polydimethylsiloxane (PDMS) microfluidic device was fabricated and integrated with the AuNPs/Au to form a PDMS-AuNPs/Au microfluidic electrochemical sensor. Water samples are transferred into and out of the sensor through a peristaltic pump and Tygon tubes, and the online COD detection was achieved using an electrochemical workstation. The linear range of the sensor is 0-400 mg/L, and the detection limit is 0.12 mg/L, which is much lower than the concentration limit of 20 mg/L specified by the Chinese national standard. In addition, five real water samples are evaluated, and the COD values are in good agreement with that of the standard method. The size of the sensor is only 30 mm×10 mm×5 mm, each measurement can be obtained within 3 minutes, and no toxic reagents are needed. In addition, the sensor has good convenience and integration, and provides a new idea for online COD detection.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2024
·Vol. 22
·期 1
·1-21
·
IF 10.6
Wang Yanan,Zhang Qi,Kan Minrui,Chang Fei,He Xiaoyun,Cheng Nan,Huang Kunlun
Au@Pt nanozyme, a bimetallic core–shell structure Au and Pt nanoparticle, has attracted significant attention due to its excellent catalytic activity and stability. Here, we propose that Au@Pt improves glucose tolerance and reduces TG after four weeks administration. The transcriptomic analysis of mouse liver tissues treated with Au@Pt nanozyme showed changes in genes related to glucose and lipid metabolism signaling pathways, including glycolysis/gluconeogenesis, pyruvate metabolism, PPAR signaling, and insulin signaling. Moreover, analysis of fecal samples from mice treated with Au@Pt nanozyme showed significant changes in the abundance of beneficial gut microbiota such as Dubosiella , Parvibacter , Enterorhabdus , Monoglobus , Lachnospiraceae_UCG-008 , Lachnospiraceae_UCG-006 , Lachnospiraceae_UCG-001 , and Christensenellaceae_R-7_group . Combined multi-omics correlation analyses revealed that the modulation of glucose and lipid metabolism by Au@Pt was strongly correlated with changes in hepatic gene expression profiles as well as changes in gut microbial profiles. Overall, our integrated multi-omics analysis demonstrated that Au@Pt nanozyme could modulate glucose and lipid metabolism by regulating the expression of key genes in the liver and altering the composition of gut microbiota, providing new insights into the potential applications of Au@Pt nanozyme in the treatment of metabolic disorder. Graphical Abstract
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Weilin Zhong,Chao Wang,Hailun Zhao,Suqing Peng,Zhipeng Tian,Riyang Shu,Ying Chen
Constructing efficient photothermal catalysts and understanding their photothermal synergistic effects for solar-driven conversion of biomass derivatives towards clean energy carriers are essential in the development of renewable energy and waste disposal. In this study, Au nanoparticles loaded on TiO 2 nanoflakes were synthesized as photothermal catalysts for bio-derived glycerol photothermal reforming hydrogen production. The results found that the generation of photogenerated carriers is a crucial process in the photothermal reforming of glycerol. In particular, the hot electrons excited by plasmonic Au nanoparticles did not participate in the hydrogen production reaction through neither direct nor indirect transfer. Instead, the hot carriers promoted the intermolecular collisions between reactants through thermalization. In addition, such generated local heat could reduce the semiconductor impedance and improve the migration efficiency of photogenerated carriers, resulting in an efficient conversion of gas phase intermediates. As obtained, photothermal enhanced reforming can improve hydrogen yield by 58%, while the hydrogen generated constant and the absorption equilibrium constant was calculated as 2.38 mmol∙g −1 ∙h −1 and 7.00 mL∙mmol −1 .
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ACS Sensors
·
2024
·
IF 8.2
Fan Zhao,Lingmin Yu,Jingfeng Wang,Wei Cao,Hao Zhang,Hairong Wang,Pu-Hong Wang,Zhihong Qiao
Achieving selective detection of ppb-level CO is important for air quality testing at industrial sites to ensure personal safety. Noble metal doping enhances charge transfer, which in turn reduces the detection limit of metal oxide gas sensors. In this work, metal–organic framework-derived Au-doped In2O3 nanotubes with high electrical conductivity are synthesized by pyrolysis of the Au-doped metal–organic framework (In-MIL-68) as a template. Gas-sensing experiments reveal that the detection limit of 0.2% Au-doped In2O3 nanotubes (0.2% Au, mass fraction) is as low as 750 ppb. Meanwhile, the sensing material shows a response value of 18.2 to 50 ppm of CO at 240 °C, which is about 2.8 times higher than that of pure In2O3. Meanwhile, the response and recovery times are short (37 s/86 s). The gas-sensing mechanism of CO is uncovered by in situ DRIFTS through the reaction intermediates. In addition, first-principles calculations suggest that Au doping of In2O3 significantly enhances its adsorption energy for CO and improves the electron transfer properties. This study reveals a novel synthesis pathway for Au-doped In2O3 nanotubular structures and their potential application in low concentration CO detection.
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ORGANIC ELECTRONICS
·
2025
·
IF 2.6
Taotao Rao,Qian Qiao,Jun Zhou,Jian Zheng,Xuan Yu,Xiaoming Yu,Cunxi Zhang,Rui Wang
Self-powered hybrid plasmonic photodetectors based on Zinc oxide (ZnO) nanorod arrays (NRAs)/ZnO quantum dots (QDs)/poly(3-hexylthiophene) (P3HT) incorporated with gold nanoparticles (Au NPs) were successfully fabricated. The photoresponse performance of the ZnO NRAs/ZnO QDs/P3HT hybrid photodetectors was enhanced by the incorporation of Au NPs. The optimal ZnO NRAs/ZnO QDs-Au(250) NPs/P3HT organic-inorganic hybrid plasmonic photodetector exhibits a photo-to-dark current ratio of 2450, a responsivity of 46 mA/W and a specific detectivity of 1.88 × 10 11 Jones under 525 nm light illumination and zero bias voltage. This study offers novel insights into the utilization of metal nanoparticles to enhance the performance of organic-inorganic hybrid photodetectors.
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JOURNAL OF CATALYSIS
·
2024
·
IF 6.5
Qiang Zhou,Xinyu Wang,Tao Xing,Mingqing Wang,Mingbo Wu,Wenting Wu
Hydrogen peroxide (H 2 O 2 ) is widely used as an oxidant for photocatalytic oxidation of methane to value-added chemicals under mild conditions, but suffers from low utilization efficiency. Herein, we propose a comprehensive strategy for the proper amount of hydroxyl radicals (•OH) generation from H 2 O 2 by regulating the Pd/Au molar ratios and the total Au-Pd contents loaded on In 2 O 3 . For the photocatalytic oxidation of methane at ambient temperature, the yield and selectivity of CH 3 OH over the optimized 1.0% AuPd 0.5 /In 2 O 3 catalyst were as high as 2187.0 μmol g −1 h −1 and 94.0% respectively, exceeding most reported literatures. Mechanism investigations revealed that the formation of Au-Pd alloys may contribute to the homolytic cleavage of H 2 O 2 into •OH radicals and improve the selectivity of •OH generation. This work provides some guidance for the delicate design of photocatalysts to manipulate selective H 2 O 2 activation and efficient photocatalytic methane oxidation.
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Journal of Physical Chemistry C
·
2024
·
IF 3.3
Wenhao Xu,Yujie Cao,Binhang Wang,Zitao Zhang,Xiang Li,Libo Sun,Guangnan Liu,Yun Tang
Metal–metal oxide nanostructures have drawn increasing research attention due to their unique properties enabled by strong interfacial interactions. However, the synthesis of metal–metal oxide nanocomposites with well-controlled architectures such as the core@shell structure remains challenging. Additionally, introducing plasmonic metal can endow the nanomaterials with photoresponsive functions, offering opportunities for optical modulation of catalytic properties. In this work, we designed and fabricated an over-reduced Au@CoOx-Co core–shell nanostructure using an improved seed growth process involving carbonyl precursors. The Au core serves as an in situ catalyst facilitating the over-reduced CoOx-Co shells, and the strong interfacial interaction introduces abundant oxygen vacancies (OVs) to provide reactive sites. Meanwhile, the Au core generates excitons under light irradiation, which can significantly enhance the activation of peroxymonosulfate (PMS) for degrading fluorine-containing pollutants. This design synergistically integrates structural design, photoelectronic regulation, and catalytic enhancement, demonstrating a promising application in the future.
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npj Clean Water
·
2025
·Vol. 8
·期 1
·1-12
·
IF 11.4
Zhu Yujiao,Yeung Pui Hong,Lo Tsz Wing,Chai Yao,Wong Yat Lam,Chen Ying,Yang Huaming,Yu Weixing,Zayats Anatoly V.,Xie Fengjia,Zhang Xuming
Photocatalytic water purification is an environmentally sustainable approach, but limited by low efficiency due to challenges with photocatalysts and mass transfer. Optofluidic microreactors can address these constraints, yet optimizing reactor configurations and photocatalyst designs remains challenging. Here, we present a novel planar packed-bed optofluidic microreactor (PPOM) using titanium dioxide nanoflowers (TNFs) decorated with gold nanoparticles (Au/TNFs) and conduct a pilot study on efficient visible light-driven water purification. Compared to TNFs in slurry-mode, the Au/TNFs achieve 46-fold enhancement in photodegradation efficiency due to the plasmonic effect, further boosted to 2,700-fold enhancement in the PPOM configuration by improving surface area, light harvesting, and mass transfer. The PPOM also shows a 7-fold efficiency increase compared to planar film-mode microreactors. Theoretical analysis elucidates the influences of plasmonic effect and reactor configuration on the enhanced photocatalytic activity, emphasizing the potential of integrated optofluidic systems and plasmonic-semiconductor heterostructures for sustainable water treatment and energy applications.
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Nanomaterials
·
2024
·Vol. 14
·期 8
·719
·
IF 4.4
Xueyan Li,Zeyi Wu,Xiangyu Song,Denghua Li,Jiajia Liu,Jiatao Zhang
Nowadays, metal oxide semiconductor gas sensors have diverse applications ranging from human health to smart agriculture with the development of Internet of Things (IoT) technologies. However, high operating temperatures and an unsatisfactory detection capability (high sensitivity, fast response/recovery speed, etc.) hinder their integration into the IoT. Herein, a ternary heterostructure was prepared by decorating WO3nanoplates with Au and SnO2nanoparticles through a facial photochemical deposition method. This was employed as a sensing material for 3-hydroxy-2-butanone (3H-2B), a biomarker ofListeria monocytogenes. These Au/SnO2–WO3nanoplate-based sensors exhibited an excellent response (Ra/Rg= 662) to 25 ppm 3H-2B, which was 24 times higher than that of pure WO3nanoplates at 140 °C. Moreover, the 3H-2B sensor showed an ultrafast response and recovery speed to 25 ppm 3H-2B as well as high selectivity. These excellent sensing performances could be attributed to the rich Au/SnO2–WO3active interfaces and the excellent transport of carriers in nanoplates. Furthermore, a wireless portable gas sensor equipped with the Au/SnO2–WO3nanoplates was assembled, which was tested using 3H-2B with known concentrations to study the possibilities of real-time gas monitoring in food quality and safety.
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Science China-Materials
·
2024
·
IF 6.8
Chai Jin,Qu Changzhen,Li Kunpeng,Liang Jiaheng,Zhou Qian,Zhuang Rong,Wang Shuo,Xu Fei,Jia Qingyan,Li Peng
Highly pathogenic-resistant bacteria infections seriously hinder the wound healing process and induce a catastrophic threat to human health. Incorporating multiple antibacterial strategies into nanostructured materials has been verified to possess paramount promise for ameliorating therapeutic efficiency against resistant bacteria. Herein, a multifunctional yolk–shell nanocomposite (Au@HCN) comprised of an aurum (Au) core and hollow carbon nanosphere (HCN) shell was prepared via one-step copolymerization and carbonization. The electron plunder by Au@HCN on the bacterial membrane leads to bacterial membrane depolarization and enhanced reactive oxygen species (ROS) metabolism, resulting in remarkable efficacy against drug-resistant bacteria under dark conditions. Moreover, the synergetic photothermal therapy (PTT) displayed significant antibacterial properties (∼98%) when exposed to near-infrared (NIR) irradiation in vitro . Meanwhile, efficient eradication of drug-resistant bacteria in the infected wound in vivo was observed under NIR exposure, thereby promoting wound healing through the prominent antibacterial properties of Au@HCN. The yolk–shell Au@HCN possesses tremendous potential for combating multidrug resistance with high efficiency.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Xiaoxiao Dong,Chang Lu,Shuaijie Guo,Siqi Zhang,Xuelian Hu,Wenliu Wang,Yiwei Tang,Shuo Wang,Xiuying Liu
A magnetic NiFe 2 O 4 @TiO 2 @Au composite was successfully synthesized via layer-by-layer assembly approach and exhibited excellent SERS performance. The composite was functionalized with an aptamer modified with Cy3, serving as the Raman signal reporter, and was hybridized with complementary DNA oligonucleotides (cDNA) to construct the NiFe 2 O 4 @TiO 2 @Au@ssDNA SERS aptasensor. This aptasensor enabled the development of a sensitive, specific, and straightforward SERS assay for acetamiprid detection, exhibiting good accuracy. Under optimized conditions, an inverse correlation was established between the acetamiprid concentration and the Raman intensity at the characteristic peak of 1132 cm −1 , spanning a range of 10 −1 -10 4 nmol/L with a LOD of 8.4 × 10 −1 pmol/L. Standard addition experiments to three types of leafy vegetables samples yielded recoveries ranging from 94.30 % to 111.83 %, with a relative standard deviation of <5.56 %. This method shows potential for detecting other hazardous substances in food and environmental samples by simply changing the corresponding aptamers and cDNA.
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