CELLULOSE
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2022
·Vol. 29
·期 4
·2553-2563
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IF 6.123
Luo Ruiqing,Liu Ruihua,Li Yongqiang,Li Yarong,He Chiyang
The main challenge in developing polymer/covalent organic framework (COF) hybrid matrix membrane is to find effective strategies for strongly attaching crystalline COF to the supporting surface as defect-free membrane layers. In this article, we demonstrated for the first time a method for the preparation of a chitosan (CS)/COF mixed matrix dual-layer membrane based on solvothermal synthesis method. A novel surface modification strategy was developed using p-phthalaldehyde as covalent linkers between COF and CS membrane substrate, and then the nitrogen-containing covalent organic framework (NCOF) membrane was further grown in situ on the modified CS membrane substrate utilizing solvothermal synthesis methods. The resultant CS/NCOF dual-layer membrane exhibited highly homogeneous texture due to the excellent compatibility between NCOF crystals and CS matrixes. The combination of NCOF and CS membrane formed a large number of channels in the nitrogen environment, enabling the CS/NCOF dual-layer membrane to have an enhanced iodine uptake capacity up to 3.15 g/g. Furthermore, the CS/NCOF dual-layer membrane could be recycled at least five times while maintaining 95% iodine capture capacity. These properties make the obtained CS/NCOF dual-layer membrane ideal absorbent material for reversible iodine capture. This ingenious dual-layer membrane preparation strategy provides a new avenue to customize synthesis of novel membrane materials for clean energy and environmental remediation. Graphical abstract
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CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Liangyu Wang,Lin Du,Mengmeng Wang,Xing Wang,Saihua Tian,Yan Chen,Xiaoyue Wang,Jie Zhang,Jun Nie,Guiping Ma
Restricted by the rigid chain structure, chitosan-based materials are very fragile and easy to break up. Herein, a stable and positively charged chitosan/Ti 3 C 2 T x suspension was successfully constructed by adjusting mixing sequence, pH and ratio of chitosan to Ti 3 C 2 T x to prepare a multifunctional membrane (P-CM) with self-standing ability, good flexibility, biocompatibility, excellent photothermal antibacterial properties , and sensitive humidity sensing properties. In the first stage, protonated chitosan acted as sugar coatings was able to be encapsulated on the surface of Ti 3 C 2 T x nanosheets by electrostatic self-assembly, in turn achieving charge reversal of the nanoparticles . In the second stage, chitosan acted as molecular needles to suture the membrane formed by chitosan/Ti 3 C 2 T x particles via vacuum filtration (VAF) with the commercial flexible poly(vinylidene fluoride) (PVDF) membrane. The as-prepared P-CM membrane simultaneously solves the problem of insufficient flexibility of a single component chitosan membrane and the poor bonding between pure Ti 3 C 2 T x membranes and substrate membrane.
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Food Bioscience
·
2022
·
IF 5.318
Bin Nie,Hong Wang,Yanwei Zhang,Chaohui Rao,Huifang Wang,Xianghua Gao,Wenfeng Li,Baolong Niu
Biodegradable chitosan (CS) films can meet the demand for sustainable development. However, the performance of pure CS membrane still exists a particular gap compared with the traditional film. Inorganic nanomaterials with the controllable release are added to improve its physical and chemical properties. Herein, a series of CS/phosphate-stabilized amorphous calcium carbonate (CS/ACCP) and CS/sodium alginate/ACCP (CS/Alginate/ACCP) composite films were prepared by the flow method. The effects of ACCP and Alginate/ACCP nanoparticles on the physical and chemical properties of the composite membrane were investigated. The results showed that the composite nanoparticles could significantly improve CS film's compactness, hydrophobicity , and mechanical properties and enhance its ultraviolet (UV) blocking ability, water resistance, and water vapor blocking ability. When the number of nanoparticles was 8%, the mechanical properties of the CS composite membrane reached optimum value, and the comprehensive performance was better. In addition, the controlled-release properties of CS composite membranes were also studied, and the antioxidant, antibacterial, biocompatibility, and fresh-keeping effects of the composite membranes were explored. The results indicated that the CS composite membranes had not only excellent bacteriostatic (72%) properties ( Escherichia coli ) but also presented well fruit preservation (15 days) properties (sugar orange). In particular, the controlled release range of CS composite membrane at 12 h was between 30% and 90%, which provided a theoretical basis for its use as an edible membrane. Therefore, based on ACCP and Alginate/ACCP nanoparticles, CS composite membranes with more excellent application value in the biological field were prepared through further optimization design.
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DESALINATION
·
2023
·
IF 9.9
Pei Xiao,Xin Li,Lei Li,Fei Liu,Yi (Alex) Wang,Jian Li
Applications of environmentally friendly and low-cost biomaterials for membrane preparation offer unparalleled advantages over traditional synthetic polymer membrane. Herein, a novel collagen/casein/chitosan composite material was designed to synthesize TFC membrane for acid recovery from acidic waste stream. A vacuum filtration method was used to precious adjust the thickness of the functional layer while glutaraldehyde was adopted as crosslinking agent to preserve surface charge property of anion-exchange membranes (AEM) at acidic conditions. The electrostatic interactions and hydrogen bonding of these biopolymers endowed the TFC membrane with enhanced stability. At optimized conditions with 0.15 mL collagen/casein/chitosan composites decoration, the TFC membrane with a functional layer thickness of around 628.4 nm exhibited an excellent acid permeance (U H + = 0.034 m h −1 ) and a high H + / Fe 2+ separation factor up to 33.8. This facile strategy provides a useful guideline for constructing highly efficient TFC membrane for acid recovery and broadens the application of biomaterials for membrane application at harsh environments.
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ACS Applied Materials & Interfaces
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2021
·
IF 9.229
Wenjuan Wang,Miaomiao Liu,Weiqun Gao,Yan Sun,Xiaoyan Dong
β-Amyloid (Aβ) fibrillogenesis is closely associated with the pathogenesis of Alzheimer’s disease (AD), so detection and inhibition of Aβ aggregation are of significance for the theranostics of AD. In this work, the coassembled nanoparticles of chitosan and hyaluronic acid cross-linked with glutaraldehyde (CHG NPs) were found to work as a theranostic agent for imaging/probing and inhibition of Aβ fibrillization both in vitro and in vivo. The biomass-based CHG NPs of high stability exhibited a wide range of excitation/emission wavelengths and showed binding affinity toward Aβ aggregates, especially for soluble Aβ oligomers. CHG NPs displayed weak emission in the monodispersed state, while they remarkably emitted increased red fluorescence upon interacting with Aβ oligomers and fibrils, showing high sensitivity with a detection limit of 0.1 nM. By comparing the different fluorescence responses of CHG NPs and Thioflavin T to Aβ aggregation, the Aβ oligomerization rate during nucleation can be determined. Moreover, the fluorescence recognition behavior of CHG NPs was selective. CHG NPs specifically bind to negatively charged amyloid aggregates but not to positively charged amyloids and negatively charged soluble proteins. Such enhancement in fluorescence emission is attributed to the clustering-triggered emission effect of CHG NPs after interaction with Aβ aggregates via various electronic conjugations and hydrogen bonding, electrostatic, and hydrophobic interactions. Besides fluorescent imaging/probing, CHG NPs over 360 μg/mL could almost completely inhibit the formation of Aβ fibrils, exhibiting the capability of regulating Aβ aggregation. In-vivo assays with Caenorhabditis elegans CL2006 demonstrated the potency of CHG NPs as an effective theranostic nanoagent for imaging Aβ plaques and inhibiting Aβ deposition. The findings proved the potential of CHG NPs for development as a potent agent for the diagnosis and treatment of AD.
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Foods
·
2021
·Vol. 10
·期 12
·3003
·
IF 4.35
Kaibo Yu,Jing Xu,Lei Zhou,Liqiang Zou,Wei Liu
Mango (Mangifera indicaLinn.) is a famous climacteric fruit containing abundant flavor and nutrients in the tropics, but it is prone to decay without suitable postharvest preservation measures. In this study, the chitosan (CH)-cinnamon essential oil (CEO) Pickering emulsion (CH-PE) coating was prepared, with cellulose nanocrystals as the emulsifier, and applied to harvested mangoes at the green stage of maturity. It was compared with a pure CH coating and a CH-CEO emulsion (CH-E) coating, prepared with the emulsifier Tween 80. Results showed that the CH-PE coating had a lower water solubility and water vapor permeability than the other coatings, which was mainly due to electrostatic interactions, and had a better sustained-release performance for CEO than the CH-E coating. During mango storage, the CH-PE coating effectively improved the appearance of mangoes at 25 °C for 12 d by reducing yellowing and dark spots, and delayed water loss. Hardness was maintained and membrane lipid peroxidation was reduced by regulating the activities of pectin methyl esterase, polygalacturonase, and peroxidase. In addition, the nutrient quality was improved by the CH-PE coating, with higher contents of total soluble solid, titratable acid, and ascorbic acid. Therefore, the CH-PE coating is promising to comprehensively maintain the postharvest quality of mangoes, due to its enhanced physical and sustained-release properties.Keywords:emulsion;cinnamon essential oil;edible coating;mango;postharvest quality
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ANALYTICAL CHEMISTRY
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2016
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IF 5.886
Lingshan Gong,Hong Dai,Shupei Zhang,Yanyu Lin
In this work, we first exposed that the application of p-type semiconductor, silver iodide-chitosan nanoparticle (SICNP), acted as peroxidase mimetic to catalyze the bioprecipitation reaction for signal-amplification photocathodic immunosensing of human interleukin-6 (IL-6). After immobilization of captured antibody onto a polyethylenimine-functionalized carbon nitride (CN) matrix, SICNPs as photoactive tags and peroxidase mimetics were labeled on secondary antibodies, which were subsequently introduced onto the sensing interface to construct sandwich immunoassay platform through antigen–antibody specific recognition. Due to the matched energy levels between CN and AgI, the photocurrent intensity and photostability of SICNP were dramatically improved with rapid separation and transportation of photogenerated carriers. Moreover, the insoluble product in effective biocatalytic precipitation reaction served as electron acceptor to scavenge the photoexcited electron, leading to great amplification of the photocurrent signal of SICNP again. With the help of multiamplification processes, this photocathodic immunosensor presented a turn-on photoelectrochemical performance for IL-6, which showed wide linear dynamic range from 10–6 to 10 pg/mL with the ultralow detection limit of 0.737 ag/mL. This work also performed the promising application of SICNP in developing an ultrasensitive, cost-effective, and enzyme-free photocathodic immunosensor for biomarkers.
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APPLIED SURFACE SCIENCE
·
2026
·
IF 6.6
Han Zhang,Lingui Li,Jianing Zhang,Yinxing Xu,Lijuan Li,Xiang Li
A TpPa-1@CS/β-CD aerogel is fabricated via freeze-drying and in-situ self-assembly. • The composite aerogel exhibits exceptional BPA adsorption capacity of 163.40 mg/g. • The TpPa-1@CS/β-CD aerogel is ultra-lightweight, elastic and regenerable. • After treatment with the aerogel, the COD of BPA meets the emission standard. The presence of bisphenol A (BPA), a significant industrial chemical, in aquatic environments poses persistent ecological risks and requires effective mitigation. Herein, a novel composite aerogel, TpPa-1@CS/β-CD, was fabricated by integrating freeze-drying and in-situ self-assembly. The TpPa-1 COF and chitosan/β-cyclodextrin (CS/β-CD) matrix provide abundant sites for synergistic BPA removal. The adsorption mechanism involves hydrogen bonding between the composite’s N- and O-containing groups and BPA hydroxyls, π-π stacking between BPA benzene rings and TpPa-1 conjugated frameworks, and hydrophobic inclusion in β-CD and TpPa-1 cavities. The aerogel exhibits a high BPA adsorption capacity of 163.40 mg/g, with kinetics and isotherm fitting the pseudo-second-order and Freundlich models, respectively. It also demonstrates ultra-lightweight, mechanical elasticity, and satisfactory regeneration. In dynamic filtration, the aerogel achieved 95.85% BPA removal at 20 mg/L. When applied to raw sewage, the aerogel achieved a BPA removal efficiency of 79.49% and reduced the COD from 174.18 to 55.99 mg/L, meeting the GB 31572–2015 emission standard. This study presents a valuable strategy for in-situ preparation of COF-based composite aerogels as high-performance adsorbents for advanced wastewater treatment. Download: Download high-res image (243KB) Download: Download full-size image
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Jin Liu,Tianhao Wang,Qilin Lv,Yunshan Meng,Zideng Gao,Shuwen Hu,Xueqin Ren
Chitosan is widely used in reactive oxygen species (ROS)-responsive films but remains great challenges owing to its weak mechanical strength and strong hydrophilicity . Herein, we synthesized novel hydrophobic crosslinked CS films with ROS-responsive properties and excellent physicochemical properties. A novel crosslinker, 2-((10-carboxydecyl)thio)succinic acid, with long-chain alkanes, three carboxyl groups, and sulfhydryl groups was synthesized and then used to produce thioether-containing crosslinked CS membranes. The results suggested that crosslinking could significantly increase the tensile strength of the film from 15.67 MPa to 24.32 MPa. The compact structure of crosslinked chitosan film improved the hydrophobicity and degradability, reduced the thermal stability and swelling rates, exhibited excellent non- cytotoxicity. The in vitro release studies revealed that crosslinked chitosan films could displayed the highest flux about 1.40 mg/ (cm 2 h) and significant NR fluorescence change over 80 %. Collectively, our results demonstrate the applicability of these films as ROS-responsive drug delivery systems.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Haoran Cui,Junjie Cai,Hanjiao He,Sheng Ding,Yi Long,Song Lin
Wound infection control is a primary clinical concern nowadays. Various innovative solutions have been developed to fabricate adaptable wound dressings with better control of infected wound healing. This work presents a facile approach by leveraging 3D printing to fabricate chitosan/glycerol into composite dressings with tailored micropatterns to improve wound healing. The bioinks of chitosan/glycerol were investigated as suitable for 3D printing. Then, three tailored micropatterns ( i.e. , sheet, strip, and mesh) with precise geometry control were 3D printed onto a commercial dressing to fabricate the micropatterned composite dressings. In vitro and in vivo studies indicate that these micropatterned dressings could speed up wound healing due to their increased water uptake capacity (up to ca. 16-fold@2 min), benign cytotoxicity (76.7 % to 90.4 % of cell viability), minor hemolytic activity (<1 %), faster blood coagulation effects (within 76.3 s), low blood coagulation index (14.5 % to 18.7 % @ 6 min), enhanced antibacterial properties (81.0 % to 86.1 % against S. aureus , 83.7 % to 96.5 % against E. coli ), and effective inhibition of wound inflammation of IL-1β and TNF-α factors. Such tailored micropatterned composite dressing is facile to obtain, highly reproducible, and cost-efficient, making it a promising implication for improved and personalized contaminated wound healing.
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Progress in Natural Science-Materials International
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2023
·
IF 4.7
Kaiting Cheng,Yiming Fang,Liang Bai,Feng Gui,Junchi Ma,Huimin Gao,Yadong Zhao,Xingtao Xu
In everyday life, traditional dressings such as band-aid and gauze are used for dealing with small wounds. However, these dressings have shortcomings such as pain caused by tearing, inapplicability to joints, single functionality, and adverse reactions. Therefore, there is a great need for an inexpensive, comfortable, and multi-functional wound dressing. In this study, quaternized chitosan (QCS) with a high degree of substitution (107.84 %) was successfully prepared and characterized using ultraviolet–visible (UV–vis) spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), and proton nuclear magnetic resonance ( 1 H NMR). A series of QCS/F127 thermosensitive hydrogels were prepared by physical cross-linking and used as potential wound dressings. Then the temperature sensitivity, hemostatic ability, antibacterial activity, and sustained drug release effect of the hydrogels were investigated to evaluate their multifunctionality as wound dressings. Finally, the effect of QCS concentration on hydrogel properties was explored. The results show that the composite hydrogels have significant hemostatic, antibacterial, and sustained drug release abilities, and they can be rapidly transformed into a gel state and adhere to skin upon reaching body temperature. In addition, the properties of the hydrogels can be adjusted by varying the concentration of QCS, which allows for the preparation of wound dressings that are responsive to needs. Therefore, multifunctional QCS/F127 hydrogels with temperature-response characteristics are of great clinical research value as wound dressings.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Xinyue Zhao,Dingyang Chen,Nan Zhang,Minsi Shi,Wei Hu,Guangli Yu,Rui Zhao
Combining adsorption with other technologies holds great potential in fast and deep arsenic ion removal. Herein, chitosan‑zirconium composite adsorptive membranes (CS-Zr CM) were successfully prepared using simple casting and sodium hydroxide coagulation strategies, which was demonstrated the use in arsenic ion-capture electrodialysis based on their good adsorption performance. In the batch adsorption tests, the maximum adsorption capacities of CS-Zr CM for As(III) and As( V ) were 134.2 mg/g and 119.5 mg/g, respectively. CS-Zr CM also exhibited satisfying adsorption selectivity and good reusability toward As(III) and As(V). However, the adsorption kinetics showed that they needed 48 h to reach the adsorption equilibrium and the adsorption ability toward trace arsenic ion was ineffective. Furthermore, CS-Zr CM was applied as the adsorptive membrane in the electrodialysis process. Under the influence of electric field, the As(III) and As( V ) removal equilibrium time was shortened to 12 h and the concentrations of As(III) and As(V) ions could be efficiently reduced to below the WHO limit in drinking water (10 μg/L), which far surpassed the physicochemical adsorption method. Such good arsenic ion removal ability of CS-Zr CM together with the ease scalable fabrication, low cost, and biodegradable properties shows its huge prospects in arsenic-containing wastewater treatment.
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