LWT-FOOD SCIENCE AND TECHNOLOGY
·
2025
·
IF 6.6
Wenbi Tuo,Jun Zhao,Xiaoli Yi,Siwei Xiong,Weidong Zhang,Yunzhi Tian,Yingying Du,Yanqing Shu,Yanan He,Yan Qu
Food safety is essential for protecting public health. This study introduces a novel microneedle (MN) patch that employs a pH-responsive colorimetric mechanism for the real-time, easy, and visible detection of meat freshness. The patch is a pH-responsive colorimetric microneedle (C3G/HAMA@MN) patch composed of eco-friendly bio-based components, specifically methacryloylated hyaluronic acid (HAMA) and cyanidin-3-O-glucoside (C3G). Its mechanical strength reaches 7 N per needle, capable of penetrating over 85% of meat tissue. The distinctive structural design allows the microneedle tip to quickly and directly penetrate the meat tissue, extracting interstitial fluid in situ and promptly transferring it to the backing layer. The backing layer visually indicates pH changes in real time. The color change from light to dark matches freshness levels at different deterioration stages. Without sophisticated instruments, consumers may notice the patch's color change in two minutes using their vision, allowing for simple and reliable food quality inspection. A powerful new instrument for on-site food safety monitoring combines real-time display, easy interpretation, and biodegradable materials.
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DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Yaohong Gu,Qianqian Pang,Zhiting Deng,Zhichao Chen,Yaling Yang
Herein, a novel fluorometric approach is developed for the precise quantification of nicotine. This method utilized the derivatizing reaction between o-phthalaldehyde (OPA) and reduced glutathione (GSH), and derivatized product with tricyclic conjugated structure generate fluorescent emission. And the derivative exhibits a quantum yield of 33.46 % and distinct fluorescence “turn-off” quenching behavior in the presence of Cu 2+ ions due to the GSH-Cu 2+ complex formation. More importantly, when nicotine is introduced reaction system, the fluorescence restored (“turn-on”) based on the nicotine-Cu 2+ complex formation. Therefore, a fluorimetric sensor for nicotine detection is developed with lower detection limit (LOD) of 0.21 μg/mL. The developed method was successfully utilized to analyze nicotine content in electronic cigarette and cigarette bag samples, yielding satisfactory recovery rates ranging from 85.2 % to 111.8 %. The obtained results demonstrated comparable accuracy and confirmed the method's reliability and practical applicability.
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DOI
PubMed
高影响因子
Advanced Science
·
2025
·
IF 14.1
Xiran Xiong,Jun Song,Shihan Li,Lu Jin,Qi He,Baohui Zhang,Yan Cao,Shanyong Yi,Yanfang Yang,Xiang Li,Juan Li,Wei Huang
O -Methylation catalyzed by plant O -methyltransferase plays a crucial role in both drug design and biosynthesis of natural products. However, their practical applications are often restricted by strict substrate specificity and a strong dependence on the expensive methyl donor S-adenosyl-L-methionine (SAM). Herein, an O -methyltransferase, SmOMT, is identified from the medicinal plant Selaginella moellendorffii , exhibiting substrate promiscuity and regioselectivity. SmOMT catalyzed the methylation of 25 structurally diverse substrates and demonstrated detectable N -methylation activity. Combined ternary complex structure and molecular dynamics studies of SmOMT elucidate its catalytic and regioselectivity mechanisms. A double mutant, SmOMT M2 , with enhanced catalytic activity is obtained based on structural analysis. To overcome SAM dependence, a cascade system for SAM regeneration is successfully constructed by coupling SmOMT M2 with a mutant halide methyltransferase, AtHMT V140T . Employing the iMARS platform, a highly active fusion enzyme, AtHMT V140T -L 95 -SmOMT M2 , is designed. This fusion enzyme outperforms the free-enzyme cascade system and facilitates the gram-scale synthesis of a series of methylated compounds with enhanced anti-inflammatory activity. This work provides a versatile methylating biocatalyst and establishes an efficient SAM regeneration methylation platform, overcoming limitations in enzymatic methylation and enabling the sustainable production of high-value pharmaceuticals.
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DOI
PubMed
高影响因子
Nature Communications
·
2026
·
IF 18.1
Chang Xingchen,Yu Tao,Wang Han,Jiang Jie,Yan Dong,Chang Jinfa,Jin Yongcheng,Yang Yang,Hou Chun-Chao
The conversion of polyethylene terephthalate waste into valuable bulk chemicals through electrochemical upcycling represents a viable strategy for waste valorization. The direct involvement of hydroxyl species is crucial for C-C bond cleavage during ethylene glycol oxidation in polyethylene terephthalate hydrolysate, thereby enhancing catalytic efficiency. However, excessive or competitive hydroxyl adsorption often suppresses ethylene glycol adsorption and activation, impeding the formation of key intermediates toward formic acid. Here we show a crystal boundary engineering strategy to construct an asymmetric Co 2+ -O-Co δ+ bridged electrocatalyst within cobalt oxides. This design integrates two catalytic sites: Co 2+ sites preferentially facilitate hydroxyl adsorption, while Co δ+ sites exhibit enhanced affinity for ethylene glycol, thereby reducing the energy barrier for formic acid formation. Consequently, the Asy-Co 2+ -O-Co δ+ exhibits a high Faradaic efficiency of 96.12% and selectivity of 93.75%. It delivers an industrial-level current density of 1000 mA cm −2 under membrane electrode assembly conditions, with competitive stability over multiple polyethylene terephthalate hydrolysate electrolysis cycles. This study provides valuable insights for the design of advanced catalysts in the upcycling of polyethylene terephthalate waste.
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高影响因子
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
·
2021
·
IF 5.234
Weiqiang Hu,Lei Wang,Zongqing Ma,Liming Yu,Yongchang Liu
This work proposed an innovative technology to fabricate Mo–La–O nanoparticles strengthened Mo alloys with ultrafine nano grains via freeze-drying and low temperature sintering . These novel nano Mo–La–O particles including La 7 Mo 7 O 30 , La 5 Mo 3 O 16 , La 6 Mo 2 O 15 , La 5 Mo 4 O 12 , La 4 Mo 2 O 11 and La 2 (MoO 6 ) remain coherent or semi-coherent interfaces with Mo matrix to strengthen their phase boundaries. Moreover, nano Mo–La–O particles enriched in excess oxygen absorb nearby impurity oxygen and then lead to the purification of Mo matrix. Furthermore, the low temperature sintered Mo–La x Mo y O z alloys possess high relative density (98.1%), which is due to the high sintering activities of ultrafine powders (56 nm). Comparing with available literature which involves oxide-dispersion-strengthened-molybdenum alloys (ODS-Mo), the freeze-dried Mo–La x Mo y O z alloys in our work possess the finest grain size (440 nm), the finest oxide particle size (mainly <5 nm), the highest hardness (495 HV 0.2 ) and high strength (1201 MPa) at 30% deformation.
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高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2026
·
IF 4.6
Shaolong Liu,Zhifeng Su,Zhiming Qiu,Xitao Guo,Minghua Liu,Yurong Yan
Biomass-derived porous carbon holds great promise as an electrode material for supercapacitors due to its low cost and sustainability. However, single-activator strategies typically fail to achieve microporous-mesoporous structure with high specific surface area (SSA) and micropore volume of such carbon materials, thereby limiting their capacitive performance. Therefore, inspired by the pyrolysis behavior of sodium lignosulfonate, we innovatively propose a novel activation system for preparing N/O/S co-doped biomass microporous-mesoporous carbon (SLCA): utilizing chitosan carbon and sodium lignosulfonate as self-doping carbon sources, potassium hydroxide as the primary activator, and sodium lignosulfonate as the self-templating activator. The microporous volume is a key factor influencing specific capacitance. Specifically, the SLCA-700 (activated at 700 °C) has a microporous-mesoporous structure with abundant N/O/S heteroatoms doping and a SSA of 2378.7 m 2 ·g −1 , and achieves a high micropore volume of 0.84 cm 3 ·g −1 , which is 0.24 cm 3 ·g −1 higher than that of the KOH activation system alone. Furthermore, the SLCA-700 electrode exhibits an outstanding specific capacitance of 305.9 F·g −1 at 0.5 A·g −1 , and supercapacitor shows excellent cycling stability (97.0% capacitance retention after 10,000 cycles). This study proposes a dual activation mechanism for preparing microporous-mesoporous carbon with a high SSA, providing a viable strategy for producing high-performance supercapacitor electrode materials.
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高影响因子
COMBUSTION AND FLAME
·
2026
·
IF 6.2
Shubao Song,Lin Zhang,Jinghua Wu,Meishuai Zou,Jiankun Shao
A detailed experimental and modeling study was conducted to investigate the high-temperature decomposition and ignition behavior of nitromethane (CH 3 NO 2 ) and its relevance to the development of a comprehensive C–N–O kinetic model. Shock tube experiments coupled with high temporal resolution and low detection limit laser absorption diagnostics were employed to measure time-resolved species profiles of NO, CO, and CH 4 during CH 3 NO 2 pyrolysis under argon-diluted conditions (1.0 % and 1.3 % CH 3 NO 2 in Ar). In addition, ignition delay times (IDTs) of CH 3 NO 2 /O 2 /Ar mixtures were measured over a wide range of equivalence ratios ( φ = 0.5, 1.0, and 2.0) at near-atmospheric pressure. To further constrain the kinetics, the rate constant for the unimolecular decomposition reaction R1 (CH 3 NO 2 (+M)=> CH 3 + NO 2 (+M)) was experimentally determined at high temperatures, the resulting rate constant data can be represented by the Arrhenius equation k R1 (1043–1350 K, 1.5 atm) = 4.98 × 10 12 exp(-44,990 cal/mol/ RT ) s -1 . A refined kinetic model for CH 3 NO 2 combustion was developed by integrating the newly obtained rate constant data of R1 and updating the CH 3 NO 2 sub-mechanism within a previously established NH 3 –syngas model. Rate of production and sensitivity analyses were performed to identify the dominant reaction pathways governing species formation, with particular emphasis on the role of R1 and its competition with secondary reactions. This work advances the understanding of nitroalkane combustion, offering a robust and transferable kinetic framework for future simulations of energetic materials in propulsion and energy systems.
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高影响因子
FOOD CONTROL
·
2026
·
IF 6.3
Yiting Duan,Weidong Su,Xinru Deng,Chongyang Liu,Qi Li,Yuan Gao,Xiuzhu Yu
Oxidized triacylglycerols (OxTGs) formed during frying degrade oil quality and raise safety concerns. To resolve oxygen provenance under frying-like conditions, a dual hydrogen–oxygen stable-isotope tracing design (D 2 O, H 2 18 O, 18 O 2 ) was applied to triolein heated at 180 °C for 0–4 h under 3 atm: natural air (NA) + H 2 O, synthetic air (SA)– 16 O 2 + H 2 18 O, and SA– 18 O 2 + D 2 O. Diagnostic fragment ions revealed five triacylglycerols and eight OxTGs dominated by hydroperoxide (–OOH) and hydroxyl (–OH) functionalities, while isotopologue ratios (M+1–M+4)/M quantified label incorporation. Pronounced enrichment occurred only under SA– 18 O 2 + D 2 O, particularly for hydroxylated OxTGs; ratios remained comparatively stable in NA + H 2 O and SA– 16 O 2 + H 2 18 O, consistent with water acting primarily as a kinetic modulator of hydroperoxide turnover and interfacial processes rather than as a direct oxygen donor to OxTGs.The labeling pattern demonstrates that oxygen incorporated into OxTGs derives primarily from molecular oxygen (O 2 ). Mechanistically grounded process controls that limit oxygen availability—such as vacuum or otherwise deaerated frying—are therefore expected to suppress OxTG formation. For decision-ready surveillance and oil-turnover management, an integrated indicator panel is recommended, combining total polar compounds (TPC), sentinel glycerol-core aldehydes (e.g., 9-oxo/10-oxo species), and representative –OOH/–OH OxTGs. Collectively, these findings clarify OxTG formation pathways and provide a practicable basis for risk-informed quality and safety control of frying oils.
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2026
·
IF 21.1
Jie Yang,Yu Luo,Zhichao Chen,Junjiang Zhu
The selective catalytic reduction of NO with NH 3 (NH 3 −SCR) reaction is governed by the interplay of surface acidity and redox activity, yet the mechanism of their cooperation remains elusive. Herein, Ce–O–W linkages were constructed on Ce/ZrO 2 to couple Ce 4+ /Ce 3+ redox cycle with tungsten-derived acidity. Operando DRIFTS and transient experiments revealed that gaseous NO reacts directly with NH 3 adsorbed on Lewis Ce 4+ sites, following an Eley–Rideal pathway. Brønsted acid sites from Ce–O–W acted as NH 4 + reservoirs, dynamically replenishing Lewis-bound NH 3 and sustaining continuous reactivity. Operando UV–vis spectroscopy confirmed that NO + NH 3 exposure reduced Ce 4+ to Ce 3+ , while O 2 re-oxidized Ce 3+ to Ce 4+ , establishing the redox cycle. Density functional theory calculations supported that NH 3 dehydrogenation on Ce sites and subsequent coupling with gaseous NO were energetically favorable, while O 2 -assisted Ce 3+ re-oxidation required the highest energy barrier. These results highlight the cooperative function of Ce–O–W acid–redox site in promoting SCR activity through dynamic L–NH 3 /B–NH 4 + interplay and sustained Ce redox cycling.
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高影响因子
CERAMICS INTERNATIONAL
·
2024
·Vol. 50
·期 24
·52228-52239
·
IF 5.1
Dongjiang Wu,Weijie Lv,Zheng Li,Xuexin Yu,Cong Zhou,Bi Zhang,Wei Wang,Huanyue Zhang,Guangyi Ma,Fangyong Niu
High-entropy oxides (HEOs) have attracted extensive research interest due to their unique structural features, customizable elemental compositions, and tunable functional properties. Nevertheless, the complexity, low efficiency, and high cost of the existing HEO synthesis methods place limitations on them. In this study, Laser directed energy deposition (LDED) was employed to synthesize (Mg, Co, Ni, Cu, Zn)O oxides. Additionally, the novelty of applying the LDED process to multicationic systems was emphasized. The comparison between specimens fabricated from mixed powder via LDED(MP) and those fabricated from pre-sintered powder via LDED(SP) encompasses macroscopic morphology, microstructure, and performance. The results showed that SP significantly enhanced the density from 86.44 % to 96.70 % compared to MP. The macro-segregation of Cu and Cu 2 O in the phase composition was observed in MP and SP. High-temperature pre-sintering promoted the solid solution formation of Co and Ni during LDED, leading to more severe micro-segregation of Co and Ni. When employed as anodes in lithium-ion batteries, MP and SP have outstanding long-term cycle stability, according to electrochemical performance studies. At a current density of 100 mAg −1 , these specimens maintained a capacity retention rate of 100 % even after 200 cycles. The initial discharge capacities of MP and SP were respectively 477.73 mAh g −1 and 373.86 mAh g −1 . This study is expected to present a novel approach for the rapid synthesis of (Mg, Co, Ni, Cu, Zn)O oxide ceramics .
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高影响因子
International Journal of Electrochemical Science
·
2023
·Vol. 11
·期 8
·6466-6476
·
IF 1.5
Changling Yan,Jin Li,Tingting Meng,Xun Liu,Ruixing Zhang,Yujuan Chen,Gongke Wang
A simple and reliable method was proposed for rapid detecting ciprofloxacin, based on molecularly imprinted technology. The molecularly imprinted ciprofloxacin hydrochloride (CPX) sensor was prepared by electropolymerization of pyrrole (Py) and o-phenylenediamine (o-PD) on the pencil graphite electrode (PGE). The performance of the sensor was characterized by square wave voltammetry (SWV) using potassium ferricyanide as molecular probe. Under optimal conditions, the sensor displayed high selectivity and stability towards CPX. A linear relationship between the change in current (Δi) and the logarithm of CPX concentrations from 1×10 −9 to 1×10 −3 mol/L was obtained with a detection limit of 7.58×10 −11 mol/L (S/N=3). Furthermore, the MIP sensor was applied for the analysis of real tablet samples with high accuracies.
研究领域:
分析化学
·
药物分析
·
电化学传感
·
分子印迹技术
·
药物残留检测
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高影响因子
MICROCHEMICAL JOURNAL
·
2021
·
IF 4.821
Zhihao Wu,Ruchun Chen,Shuang Pan,Hui Liu,Xiaoli Hu
Herein, a convenient method is developed for ratiometric fluorescence detection of ATP (adenosine triphosphate) based on CDs-OPD (carbon dots- o-phenylenediamine). In the absence of ATP, oxOPD, the colored oxidation product of OPD fabricated by a redox reaction occurred between OPD and Cu 2+ , not only quenches the fluorescence of CDs, but also emits a yellow fluorescence which acts as another signal element. However, ATP will compete with OPD to chelate Cu 2+ inhibiting the redox reaction, which hampers the formation of oxOPD resulting in the diminution of IFE (inner filter effect) between CDs and oxOPD, then the fluorescence of CDs restores. ATP-induced dual-signal response of the CDs-OPD/Cu 2+ system makes ratiometric assay possible. The method exhibits high sensitivity toward ATP with a detection limit of 0.43 μmol L −1 . Furthermore, the semi-quantitative measurement of ATP is available by naked eyes through the color of fluorescence and solution. Finally, the developed method is employed for the quantification of ATP in practical samples with satisfactory results.
研究领域:
分析化学
·
生物传感
·
纳米材料
·
分子生物学
·
临床检验
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高影响因子
危险品化学品经营许可证（带存储）