ACS Nano
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2025
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IF 16
Lianxue Zhang,Yun Teng,Hai Yang,Jianxiang Huang,Zhaoqi Shi,Cenhao Wu,Zaixing Yang,Liquan Huang,Jun Zou,Ruhong Zhou
Chordoma presents a formidable therapeutic challenge due to its distinct anatomical location, thus complicating its complete surgical resection coupled with marked resistance to both radiotherapy and chemotherapy. Currently, effective systemic therapies remain unavailable, contributing to a poor prognosis for patients. To address this critical unmet need, we have developed a targeted drug delivery system tailored to the tumor biology of chordoma. This system encapsulates the CDK7 inhibitor THZ1 within nanoparticles featuring diselenide bonds as dual-responsive release triggers. Upon exposure to low-dose X-ray irradiation (e.g., 2 Gy) and to the elevated reactive oxygen species (ROS) level in the tumor microenvironment, these diselenide bonds are cleaved and transformed into selenic acid (RSeOOH), which subsequently initiates rapid carrier disassembly and drug release. The synergy between RSeOOH and THZ1 enhances radiotherapy efficacy by modulating p53 signaling, inducing apoptosis, and promoting G2/M phase cell cycle arrest in U-CH1 cells, thereby overcoming the radiotherapy resistance commonly seen in chordoma. To further improve tumor-specificity, we functionalize the carrier with the EGFR-targeting GE11 peptide, which drives selective drug accumulation at tumor sites. In murine models, this delivery system has demonstrated substantial efficacy in combination with radiochemotherapy and yet produces minimal toxicity. Molecular dynamics simulations have further elucidated carrier self-assembly mechanisms, guiding the rational design of this nanoplatform.
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ACS Nano
·
2025
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IF 16
Xueyang Li,Jun Du,Yuxi Jia,Shu Hu,Gang Li,Boyu Zhang,Jingyi Zhu,Jingwei Guo,Kaifeng Wu
Liquid-state optical gain media are desired for high-power lasing applications due to their easier heat management than solid-state media, as well as for the emerging field of optofluidics. Colloidal quantum dots (QDs) are solution-processed materials that carry many attractive properties suitable for liquid lasing. To date, however, their lasing action is often achieved in close-packed films, as a high volume fraction of QDs is required for stimulated emission to outpace the ultrafast Auger decay of gain-active multiexciton states. Here we report liquid lasing from color-tunable (red, orange, and green) alloyed core/shell QDs with impeded Auger recombination. Lasing action is achieved by loading the QD-solutions into cavities under quasi-continuous-wave excitation. The light amplification behaviors of QD-solutions under ambient conditions are much more stable compared to those of both solid-state QD-films and dye solutions. Compatibility with aqueous solvents and ease of scalability are also demonstrated. An optimized optical power efficiency of 17.2% has been achieved. These results indicate that liquid lasing from colloidal QDs holds strong promise for real-world implementation.
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ACS Applied Optical Materials
·
2025
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IF 3.8
Lei Chen,Hui Jiang,Fanghai Liu,Syed Aamir Hussain,Hossein Chamkouri,Yang Song,Ping Chen,Asad Ali,Xianghua Wang
As an alternative to toxic Cd-based blue light-emitting quantum dots (QDs) and chemically unstable perovskite ones, heavy-metal-free and stable ZnSe QDs have great potential for quantum dot light-emitting diode (QLED) displays. Through overcoming the challenge of controllable synthesis of ZnSe QDs with desirable properties, this work reported the synthesis of super-narrow-band blue-emitting ZnSe/ZnS core/shell QDs with full width at half-maximum (FWHM) of photoluminescence/electroluminescence as narrow as 19/20 nm, peaked at 446/449 nm, respectively. The crystallization of the core/shell QDs was well controlled by systematic optimization on the molar ratios of cations to anions and the amount of precursor addition. The coating shell of ZnS, which has a wider band gap than ZnSe, could effectively suppresses the fluorescence tail in the emission spectrum that is caused by defects on the ZnSe core surface, narrowing the FWHM of the emission spectrum and increasing the fluorescence quantum yield of ZnSe/ZnS core/shell QDs. The prepared QLED using ZnSe/ZnS core/shell QDs exhibits superior color purity, particularly suitable for display applications. This work opens up a new route to synthesizing heavy-metal-free ultra-narrow-band blue-emitting QDs.
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LANGMUIR
·
2025
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IF 3.9
Liang Li,Chao-qun Wu,Zhi-xuan Zhang,Nan Zhang,Ting Huang,Yong Wang
The rapid development of modern industry has exacerbated water pollution, posing significant threats to environmental sustainability and human health. Semiconductor heterostructures have emerged as a promising strategy to enhance the photochemical properties and catalytic activity of heterogeneous catalysts, offering a viable solution to water pollution challenges. In this study, a series of CeO2/CdSe catalysts was successfully synthesized via chemical deposition. The results demonstrate that CdSe nanoparticles could effectively modulate the band gap, enhance visible light absorption ability, and improve the photochemical performance of CeO2/CdSe composites. The catalytic activity and practical application prospects of the as-synthesized samples were evaluated by reducing hexavalent chromium (Cr(VI)) and decomposing tetracycline hydrochloride (TCH). CeO2/CdSe composites exhibited significantly higher photocatalytic activities compared to pure CdSe and CeO2. Notably, CeO2/0.6CdSe demonstrated the highest photocatalytic activity, achieving 93.6% removal of Cr(VI), which was 4.39 and 1.77 times as high as those of pure CeO2 and CdSe in sequence. Furthermore, CeO2/0.6CdSe achieved a remarkable TCH removal rate of 97.0%. The enhanced photocatalytic performance of CeO2/0.6CdSe is attributed to the formation of heterojunction structures between CdSe and CeO2, which facilitates efficient charge separation and transfer. Cyclic experiments confirmed the excellent anti-interference ability and sustainability of CeO2/0.6CdSe. Reduction mechanisms of Cr(VI) and degradation mechanisms of TCH were thoroughly investigated, with DFT mechanistic analysis providing further insights into the superior catalytic activity of CeO2/0.6CdSe. This work highlights the potential of CeO2/0.6CdSe as a highly efficient photocatalyst with broad applications in wastewater treatment.
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Journal of Energy Chemistry
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2025
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IF 14.9
Chaoran Yang,Shuyu Liang,Cong Zhang,Tianyu Zhang,Wenfu Xie,Min Li,Qiang Wang
Copper (Cu)-based catalysts have demonstrated promising selectivity and activity in electroreducing CO 2 to multi-carbon (C 2+ ) products. Among them, oxide-derived Cu catalysts exhibit high selectivity for C 2+ products in the CO 2 electroreduction reaction (CO 2 RR). Cu chalcogenide-derived catalysts offer a promising approach to tune the electronic structure of Cu sites via surface reconstruction, thereby affecting the product distribution. However, the effect of in-situ anion dissolution, especially Se ions, on the electronic structure of Cu selenides at negative potentials remains overlooked, despite its potential to significantly affect catalytic activity. In this study, we developed a series of Cu selenide catalysts with varying Cu/Se ratios to optimize electronic structures and enhance CO 2 RR performance. Among them, Cu 1.8 Se, featuring Cu vacancies, exhibited the highest activity for C 2+ products formation and the highest C 2+ /C 1 products ratio, nearly 2–3 times greater than the others. This catalyst also demonstrated good stability over 38 h of electrolysis under −450 mA cm −2 , with a maximum C 2+ products Faradaic efficiency (FE) of up to 70 %. In-situ surface reconstruction analysis revealed Se loss and Cu + /Cu 2+ reduction of the initial Cu 1.8 Se catalyst, forming Cu/Cu x Se structures with Cu vacancies, identified as the real active sites. Density functional theory (DFT) calculations and in-situ infrared absorption spectroscopy confirmed that Cu vacancies play a critical role in stabilizing *CHOCO intermediates for C–C coupling while suppressing hydrogen evolution reaction and C 1 products formation. These findings highlight Cu vacancy engineering as an effective strategy for enhancing C 2+ selectivity in CO 2 RR.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2025
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IF 21.1
Ziwei Ma,Jingyi Wang,Wei Wang,Xueyi Song,Yating Liu,Shaobin Wang,Yunjin Yao
We engineered a NiSe/Ni₃Se₂ heterostructure on nickel foam that activates formic acid for rapid hexavalent chromium detoxification. We used one-step hydrothermal growth and probed structure and mechanism by diffraction and spectroscopy, electron microscopy, electron paramagnetic resonance with 5,5-dimethyl-1-pyrroline N-oxide, and batch and fixed-bed tests. The optimized catalyst removed 99.7% of 50 mg L⁻¹ hexavalent chromium in 40 minutes at 25 °C, achieved full removal of 1 mg L⁻¹ in 20 minutes, tolerated common ions, and maintained 100% removal for 180 h in continuous flow. Mechanistic analyses show a radical pathway dominated by hydrogen radicals (H ⁎ ) and carbon dioxide radical anions ( C O 2 • − ), promoted by selenium vacancies and tightly coupled nickel selenide interfaces that accelerate formic-acid activation and interfacial charge transfer. Operating without external energy input, this monolithic architecture avoids powder recovery and minimizes pressure drop and cost, offering a general route to defect-engineered selenides for efficient, low-cost environmental redox remediation.
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ADVANCED MATERIALS
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2025
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IF 26.8
Zengguang Shi,Yukun Xiao,Mian Li,Jianfeng Cai,Yanmei Chen,Jun Jiang,Xiaoping Ouyang,Zhifang Chai,Qing Huang
Van der Waals (vdW) layered materials have gained significant attention owing to their distinctive structure and unique properties. The weak interlayer bonding in vdW layered materials enables guest atom intercalation, allowing precise tuning of their physical and chemical properties. In this work, a ternary compound, Ni x In 2 Se 3 (x = 0–0.3), with Ni randomly occupying the interlayers of In 2 Se 3 , is synthesized via an intercalation route driven by electron injection. The intercalated Ni atoms act as “anchor points” within the interlayer of In 2 Se 3 , which effectively suppresses the phase transition of In 2 Se 3 at elevated temperatures. Furthermore, the disordered Ni intercalation significantly enhanced the electrical conductivity of In 2 Se 3 through electron injection, while reducing the thermal conductivity due to the interlayer phonon scattering, leading to an improved thermoelectric performance. For instance, the thermoelectric figure of merit (ZT) of Ni 0.3 In 2 Se 3 increased by 86% (in-plane) and 222% (out-of-plane) compared to In 2 Se 3 at 500 °C. These findings not only provide an effective strategy to enhance the performance of layered thermoelectric materials but also demonstrate the potential of intercalation chemistry for expanding the application scope of van der Waals (vdW) layered materials.
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ADVANCED FUNCTIONAL MATERIALS
·
2025
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IF 19
Hu Li,Hongbin Lin,Xiaohui Liao,Weiqin Huang,Jinrui Cai,Limei Lin,Dong Wei,Zhiping Huang,Zhigao Huang,Shuiyuan Chen,Wei Zhang,Guilin Chen
Cadmium sulfide (CdS) persists as the standard electron transport layer (ETL) in high-efficiency Sb 2 (S,Se) 3 solar cells. However, its narrow bandgap imposes critical performance limitations through parasitic short-wavelength absorption and interface mismatch. Here, this bottleneck is shattered through an innovative in situ ozone doping strategy. This approach revolutionizes CdS ETLs by simultaneously: 1) Widening the bandgap of CdS ETL to drastically suppress parasitic short-wavelength photon loss; 2) Triggering a hexagonal-to-cubic phase transition that disrupts coherent Sb 2 O 3 impurity growth during Sb 2 (S,Se) 3 deposition; and 3) Engineering an oxygen-rich, defect-resistant FTO/CdS interface (DFT-validated), thereby slashing recombination and enabling superior carrier extraction. As a result, a certified world-record power conversion efficiency of 9.0% for carbon-based Sb 2 (S,Se) 3 solar cell is achieved ( V OC of 0.4908 V, J SC of 26.88 mA cm −2 , and FF of 68.19%) using an FTO/CdS:O/Sb 2 (S,Se) 3 /PbS/carbon configuration. This work, beyond setting a new benchmark for carbon-based Sb 2 (S,Se) 3 solar cells, shows that these devices demonstrate exceptional intrinsic stability under long-term and extreme damp-heat conditions without encapsulation, thus propelling Sb 2 (S,Se) 3 technology toward commercial viability.
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ACS Nano
·
2025
·
IF 16
Weite Meng,Lixiang Xu,Shaoqing Lu,Mingquan Li,Mengyao Li,Yu Zhang,Qingyue Wang,Wen-Jun Wang,Siqi Huo,Miguel A. Bañares,Marisol Martin-Gonzalez,Maria Ibáñez,Andreu Cabot,Min Hong,Yu Liu,Khak Ho Lim
SnTe has attracted significant research interest as a lead-free alternative to PbTe; however, its intrinsically high hole concentration results in an undesirably low Seebeck coefficient and elevated electronic thermal conductivity, thus significantly limiting its thermoelectric (TE) performance. Herein, we present a cost-effective, binary thiol-amine-mediated colloidal synthesis method to synthesize Bi-doped SnTe nanoparticles, eliminating the use of tri-n-octylphosphine-based precursors. The introduction of an electron-rich Bi dopant reduces the hole concentration and increases the Seebeck coefficient. Furthermore, post-synthetic surface treatment with chalcogenidocadmate complexes promotes atomic interdiffusion during annealing and consolidation, leading to compositional redistribution and modulation of the electronic band structure. Density functional theory (DFT) calculations reveal that co-modification via Bi doping and CdSe-derived chalcogen incorporation reduces the energy offset at the valence band maxima from 0.30 eV to 0.10 eV, thereby enhancing valence band degeneracy. The synergistic structural and electronic band structure modulations produce an SnTe-based material with a record high power factor of 2.1 mW m–1 K–2 at 900 K, a maximum TE figure of merit (zT) of 1.2, and a promising theoretical conversion efficiency of 8.3%. This study reports a versatile and scalable colloidal synthesis strategy that integrates hierarchical structural modulation with electronic band engineering, offering a synergistic route to significantly enhance the TE performance.
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Frontiers in Plant Science
·
2025
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IF 4.8
Solomon Musoke Ssemalawa,Emmanuel Osei Asamoah,Muhammad Raza Farooq,Gary Bañuelos,Yuanqi Wang,Haoyuan Sun,Pincheng Rao,Yukun Guo,Youtao Chen,Xuebin Yin
Selenium (Se) biofortification of crops presents a sustainable strategy to address Se deficiency, which globally affects nearly one billion people. Although selenite [Se(IV)] fertilizers are commonly used for biofortification strategies, concerns over their potential toxicity in plants and low bioaccessibility have prompted interest in alternative Se sources, such as biogenic Se nanoparticles (BSeNPs). A field study was conducted to explore the effects of foliar BSeNPs and Se(IV) at 5, 10, and 20 mg L-¹ on soybean growth, nutritional quality, Se speciation, and bioaccessibility. Application of BSeNPs at 5 mg L-¹ enhanced shoot biomass (54.2%), seed protein content (62.3%), and total amino acids (76.2%) compared to both the control and corresponding Se(IV) treatments. Enhanced antioxidant enzyme responses (SOD, POD) and a decline in lipid peroxidation (MDA) were also observed with BSeNPs application, indicating enhanced stress tolerance. While Se(IV) led to higher total Se accumulation, BSeNPs promoted greater enrichment of organic Se species (SeMet, SeCys, MeSeCys). In vitro digestion showed that total bioaccessible Se (gastric + intestinal) ranged from 45-56% for BSeNPs versus 19.6-34% for Se(IV). In conclusion, these findings indicate that foliar BSeNPs at 5–10 mg L-¹ were more effective than Se(IV) for improving seed nutritional quality and Se bioaccessibility in soybean biofortification.
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APPLIED SURFACE SCIENCE
·
2025
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IF 6.9
Shaobo Huang,Fanhui Meng,Zexin Liang,Mengqi Li
The pursuit of sustainable hydrogen production via water electrolysis urgently demands electrocatalysts reconciling industrial-grade activity, durability, and cost-effectiveness for the hydrogen evolution reaction. While transition metal selenides (TMSs) offer noble-metal alternatives with tunable electronic structures, monophasic variants suffer from compromised charge transfer kinetics, limited active site exposure, and cathodic degradation. Herein, we propose selenium anion electric field engineering via molybdenum ions regulated heterointerface construction in Ni 3 Se 4 /MoSe 2 heterojunctions anchored on nickel foam (denoted as Ni 3 Se 4 /MoSe 2 @NF). Multiscale mechanistic studies reveal that the reconstructed built-in electric field around the selenium anions in MoSe 2 demonstrates a lower hydrogen adsorption free energy (ΔG H* = 0.166 eV) via d-band center, with accelerating interfacial charge transfer. The resultant catalyst achieves an ultralow overpotential of 60 mV at 10 mA cm −2 (η 10 ) with a Tafel slope of 65.17 mV dec −1 . Particularly noteworthy is its industrial-grade stability, which exhibits only a 20 mV (η 100 ) increase after 200 h of continuous operation in 1 M KOH, coupled with near-unity Faradaic efficiency (over 98 %). This work establishes a heterointerface microenvironment regulation paradigm to break the activity-stability trade-off, providing a universal design principle for durable, high-flux water electrolysis.
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NEW JOURNAL OF CHEMISTRY
·
2025
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IF 2.5
Zefeng Chenᵃᵇᶜ,Huan Liu,Xingwei Sun,Qi Wangᵃᵇᶜ,Weiyan Sun
Tungsten (W, 5d 4 6s 2 ), a transition metal, readily provides valence electrons during chemical reactions. Leveraging this property, this work employs a one-step hydrothermal method to introduce the strongly electronegative nonmetals oxygen (O) and selenium (Se) onto an oxidized carbon cloth (OCC) substrate, resulting in the fabrication of the electrode materials W18O49/OCC and WSe2/OCC. Material characterization and electrochemical performance analyses indicate that Se performs better in optimizing the chemical states of W, which exhibits characteristics of coexisting multiple valence states (W 4+ , W 5+ , W 6+ ). This enhances favorable sites for electron migration in subsequent electrochemical reactions, thereby improving the electrochemical performance of WSe2/OCC. Kinetic calculations reveal that the energy storage process of WSe2/OCC features both capacitive and diffusion control. Compared to W18O49/OCC, WSe2/OCC maintains a certain level of capacitive control during electrochemical reactions while allowing electrons at the liquid-solid interface and the near-surface to migrate into the bulk more easily via diffusion. This activation of internal redox reactions results in commendable performance of WSe2/OCC across a series of electrochemical tests (352.1 F g -1 at 1 A g -1 ). Furthermore, the WSe2/OCC exhibits excellent cycling stability, retaining 100 % of its initial capacitance after 10,000 cycles at 10 A g -1 , along with remarkable bending resistance.
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危险品化学品经营许可证（带存储）