ACS Catalysis
·
2017
·
IF 10.614
Wenwu Zhou,Meifang Liu,Qing Zhang,Qiang Wei,Sijia Ding,Yasong Zhou
Mesoporous MY-xGa zeolites exhibiting both crystallized pore walls and narrowly dispersed mesopores with different Ga content were successfully synthesized. The synthesized samples were characterized by XRD, N2 adsorption desorption isotherms, SEM, TEM, XPS, FTIR, 29Si MAS NMR, 71Ga MAS NMR, and Py-FTIR methods. The results show that the synthesized samples exhibit unique open channel like mesopore systems and outstanding crystallite natures; no nonframework Ga species were observed over the MY-xGa series samples, and their acidic properties can be modulated by varying the Ga/Al ratio in the initial synthesis gel. The corresponding NiMo/HMY-xGa catalysts were prepared via the incipient wetness coimpregnation method; the morphologies of the sulfide catalysts were characterized by HRTEM, and the covalent states of the active metals were characterized by XPS. The catalytic activities of the investigated catalysts for the 4,6-DMDBT HDS reaction were assessed, and the collected products were analyzed by GC and GC-MS methods. The catalyst NiMo/HMY-0.5Ga showed the highest catalytic activity due to the synergistic effect of modulated acidic properties, excellent morphology, highest sulfidation degree, and proper proportion of NiMoS phase. More importantly, 4-MDBT, DBT, and BP were observed and identified as the products of the 4,6-DMDBT HDS reaction, designated as the demethylation pathway (DM) for the 4,6-DMDBT HDS reaction. Finally, a reaction network including DDS, HYD, ISO, and DM pathways for the 4,6-DMDBT HDS reaction over catalyst NiMo/HMY-0.5Ga was proposed.
研究领域:
催化化学
·
材料科学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 51
·45864-45872
·
IF 3.289
Yafei Wang,Jiang Fan,Tianyi Li,Qiong Wang,Junwei Shi,Zuoming Qu,Hua Tan,Yu Liu,Weiguo Zhu
Two binuclear platinum metallomesogens possessing a 6,12-dihydro-indeno[1,2-b]fluorene bridge, FJ-1 and FJ-2, have been synthesised and characterised by 1H and 13C NMR, TOF-MS and elemental analysis. Their thermal properties were studied by polarised optical microscopy and differential scanning calorimetry. Upon photoexcitation in solution, both complexes exhibited dual fluorescence (1π–π*)/phosphorescence (3π–π*) emission covering most of the visible spectrum (from about 460 nm to 750 nm). This uncommon behaviour has been further investigated by time-resolved optical spectroscopy, including nanosecond time-resolved transient absorption spectroscopy, and further insights were obtained by means of density functional theory (DFT) and time-dependent DFT (TD-DFT). An organic light-emitting diode (OLED) using FJ-1 was prepared. Importantly the two emission bands are retained in electroluminescence. This result suggests that controlling spin–orbit coupling to obtain dual emission can provide an effective way of achieving broadband emission based on a single molecule.
研究领域:
化学
·
材料科学
·
光物理学
✓ 已验证
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2026
·
IF 6
Jialong Wang,Jinmeng Xiang,Huihui Cao,Renze Chen,Xinyu Long,Changheng Chen,Jiwen Chang,Chongfeng Guo
Cr 3+ -activated phosphor has become the mainstream choice to obtain broadband near-infrared phosphor-converted light-emitting diodes (NIR pc-LED) for the applications of bio-imaging and component nondestructive detection. However, exploring efficient and stable Cr 3+ -activated NIR phosphors is still an important yet formidable challenge. Herein, a series of Na y K 3- y LiMg 4 (Si 2 O 5 ) 6 :Cr 3+ phosphors was synthesized, which exhibits a broadband emission spectrum spanning 650-1100 nm. Utilizing the innovative non-main lattice substitution strategy, the internal quantum efficiency (IQE) of Cr 3+ was enhanced from 21% to 80%, and thermal stability was also improved from 42% to 70%@150 °C. Based on the first-principles theory calculation, the IQE and thermal stability improvement are attributed to the strengthened local structure stability around Cr 3+ caused by the introducing of Na + . Finally, a NIR pc-LED device was packaged by combining the optimized Na 3 LiMg 4 (Si 2 O 5 ) 6 :4%Cr 3+ phosphor with blue LED chip, which demonstrates potential applications in biological imaging and night vision systems.
✓ 已验证
DOI
高影响因子
POLYMER
·
2026
·
IF 5.1
Yuzeng Li,Zhen Fan,Zhenyu Feng,Zixiang Xu,Nurimangul Muntiza,Yi Ru,Qinran Li,Hongfeng Zhang,Jin Zhao,Qiliang Deng,Donglan Sun,Tianjun Liu
A novel strategy for cytochrome c (Cyt c) selective recognition with the epitope imprinting and host-guest interaction dual-mechanism recognition was developed via reversible addition-fragmentation chain transfer polymerization regulated by a cucurbit[6]uril-functionalized chain transfer agent (CB[6]-CPAD). CB[6]-CPAD attaches to N-terminal epitope GI-9 through host-guest interactions between cucurbit[6]uril and lysine-residue. It regulates the imprinted polymers via the modulatory effect of disulfide esters, thereby enhancing the accessibility of cucurbit[6]uril within the imprinted sites. After polymerization and template removal, the imprinted particles exhibited well binding affinity for GI-9 (8.40 mg⋅g -1 , IF = 1.62) and Cyt c (11.32 mg⋅g -1 , IF = 1.62) at 45°C and obvious selective recognition of Cyt c over other proteins with a significantly higher IF, which were driven by the combination of molecular imprinting and host-guest interactions. It indicated that the construction of temperature-sensitive dual-mechanism recognition combining epitope imprinting and host-guest interactions can effectively achieve selective recognition of the target protein.
✓ 已验证
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2026
·
IF 7.3
Ruizhi Tang,Shujuan Ma,Quan Bai,Yangyang Bian,Zichao Tang,Junjie Ou
Host–guest interactions by artificially synthesized macrocyclic molecules, such as cucurbit[n]uril (CB[n], n refers to the number of glycoluril units), exhibited comparable affinity to natural biological interactions, offering orthogonal selectivities. These unique high-affinity interactions are crucial in bioseparation, particularly in the separation of complex biomacromolecules. However, to date, the application of supramolecular systems in bioseparation remains insufficient and challenging. In this work, a site-specific host–guest interaction-based method by CB[6] and CB[7] was developed for the selective enrichment of basic peptides, and their recognition for basic lysine/arginine (K/R) residues exhibited distinct selectivity. Although they both exhibited affinity to basic peptides, CB[6] tended to bind to peptides containing multiple K/R residues, while CB[7] preferred to adsorb peptides containing both phenylalanine residues and basic K/R residues. This difference was attributed to their distinct cavity sizes. Furthermore, CB[6]-containing monolith was employed for the enrichment of basic peptides from mouse liver sample digested with Staphylococcus aureus protease V8 (Glu-C). It is noteworthy that basic peptides containing 3–4 K/R residues can be successfully enriched, whereas those with more than 5 K/R residues cannot be effectively eluted. It was also observed that 1043 unique peptides were newly identified from 2.5 μg of mouse liver after the capture of basic peptides, with a markable increase in the identification coverage (31%). These newly identified peptides are generally more acidic and shorter than those depleted by CB[6], with median isoelectric point (pI) values of 5.8 and 7.0 and median lengths of 10 and 16 amino acids, respectively.
✓ 已验证
DOI
PubMed
高影响因子
Pharmaceutics
·
2022
·Vol. 14
·期 11
·2534
·
IF 6.525
Bo Wei,Yuanfang Li,Meiying Ao,Wenxiang Shao,Kun Wang,Tong Rong,Yun Zhou,Yong Chen
Previously, we found that exogenous ganglioside GM3 had an antiatherosclerotic efficacy and that its antiatherosclerotic efficacy could be enhanced by reconstituted high-density lipoprotein (rHDL). In this study, we hypothesized that GM3-functionalized rHDL (i.e., GM3-rHDL) as a nanocarrier can promote the efficacy of traditional antiatherosclerotic drugs (e.g., statins). To test this hypothesis, lovastatin (LT) was used as a representative of statins, and LT-loaded GM3-rHDL nanoparticle (LT-GM3-rHDL or[email protected]; a mean size of ~142 nm) and multiple controls (e.g., GM3-rHDL without LT, LT-loaded rHDL or LT-rHDL, and other nanoparticles) were prepared. By using two different microsphere-based methods, the presences of apolipoprotein A-I (apoA-I) and/or GM3 in nanoparticles and the apoA-I-mediated macrophage-targeting ability of apoA-I/rHDL-containing nanoparticles were verified in vitro. Moreover, LT-GM3-rHDL nanoparticle had a slowly sustained LT release in vitro and the strongest inhibitory effect on the foam cell formation of macrophages (a key event of atherogenesis). After single administration of rHDL-based nanoparticles, a higher LT concentration was detected shortly in the atherosclerotic plaques of apoE−/−mice than non-rHDL-based nanoparticles, suggesting the in vivo plaque-targeting ability of apoA-I/rHDL-containing nanoparticles. Finally, among all nanoparticles LT-GM3-rHDL induced the largest decreases in the contents of blood lipids and in the areas of atherosclerotic plaques at various aortic locations in apoE−/−mice fed a high-fat diet for 12 weeks, supporting that LT-GM3-rHDL has the best in vivo antiatherosclerotic efficacy among the tested nanoparticles. Our data imply that GM3-functionalized rHDL (i.e., GM3-rHDL) can be utilized as a novel nanocarrier to enhance the efficacy of traditional antiatherosclerotic drugs (e.g., statins).Keywords:ganglioside GM3;atherosclerosis;reconstituted high-density lipoprotein (rHDL);lovastatin (LT);drug delivery system;statins;ApoA-I
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2022
·
IF 6.056
Qibin Li,Quanyi Chen,Yueying Wu,Zhibao Chen,Ying Liu,Zhijia Fang,Qi Deng
The bacteriocin CAMT6 is a novel bacteriocin produced by Enterococcus durans YQ-6 isolated from Larimichthys polyactis in the South China Sea. In this study, the bacteriocin CAMT6 was purified by extraction using ethyl acetate, Sephadex LH-20 column chromatography, cation exchange chromatography and reversed-phase high-performance liquid chromatography, in sequence. The Liquid Chromatograph Triple Quadrupole Mass Spectrometer (LC-MS/MS) analysis revealed that the relative molecular mass and amino acid sequence of the bacteriocin CAMT6 were 1254.63 Da and N-GAVHDVKDVLDS, respectively. Combined with the circular dichroism (CD) spectroscopy results, CAMT6 was determined to be a novel Class IId bacteriocin. CAMT6 exhibited broad-spectrum antibacterial activity, inhibiting both gram-negative and gram-positive bacteria, even fungi. CAMT6 exhibited strong temperature stability, was stable over pH 2–7, and was inactivated by proteases. CAMT6 also significantly removed L. monocytogenes biofilms and inhibited L. monocytogenes by disrupting the permeability of the cell membrane. Furthermore, CAMT6 can effectively inhibit the growth of L. monocytogenes in chicken breast. These results suggest that the bacteriocin CAMT6 could serve as a potential biological preservative for food.
✓ 已验证
产品关联
DOI
高影响因子
RENEWABLE ENERGY
·
2022
·
IF 8.634
Quan Wang,Wenlei Xie,Lihong Guo
The development of feasible ecofriendly processes for biodiesel production is highly desirable to meet the requirement of green chemistry and sustainable development. To reach this goal, the molybdenum and zirconium oxides were incorporated into commercial available KIT-6, mesoporous silica nanoparticle , by a solvothermal method, to form MoO 3 /ZrO 2 /KIT-6 catalyst. The targeted solid composite catalysts were structurally characterized using XRD , TEM, SEM, XPS , EDS, TG, and nitrogen porosimetry measurement. The characterization results showed that the ordered porous structure of the support was well persevered with high surface area, and the molybdenum and zirconium oxides could be highly dispersed on the mesoporous support. The acidic nature of the solid catalyst was evaluated in detail by means of NH 3 -TPD and infrared spectra of adsorbed pyridine techniques. It was indicated that the acidities of the solid catalysts, with both Brønsted and Lewis acid sites, could greatly affected their catalytic activity . This catalyst displayed high activities to the transesterification of triglycerides and esterification of free fatty acids (FFAs) simultaneously owing to the synergistic effect of Brønsted and Lewis acid sites, thus achieving one-pot heterogeneous production of biodiesel as the low-quality oil was used as feedstocks . The influence of reaction parameters and the catalyst reusability were also investigated, and the best oil conversion of 92.7% was obtained under the optimized reaction conditions. The targeted catalyst exhibited a better FFAs and water tolerant for the reaction, advantageously with no noticeable decline in the catalytic performance even after five reaction cycles.
✓ 已验证
产品关联
DOI
高影响因子
DALTON TRANSACTIONS
·
2022
·Vol. 51
·期 11
·4414-4422
·
IF 4.569
Zhi Wang,Xu Li,Mingyang Li,Jinxing Zhao,Zhenyang Liu,Dawei Wang,Li Guan,Fenghe Wang
With the increasing demand for new inorganic functional materials, more and more attention is paid to rare earth ion doped luminescent materials. In this work, an Eu2+ doped Ba4La6O(SiO4)6 phosphor was synthesized by the high temperature solid-phase method. In the phosphor, two Ba2+ sites could be occupied by Eu2+ cations to provide two different kinds of coordination environments, resulting in broad emitting bands in the range of 450–630 nm and ultra-wide excitation bands in the range of 250–500 nm. The presence of two different Eu2+ emitting centers is verified by measuring the photoluminescence spectra and decay curves in Ba4La6O(SiO4)6 phosphors. The temperature dependence of emission intensity and full width at half maximum of Eu2+ in the range of 293–453 K were investigated systematically. The substitution of Ba2+ by Sr2+ can adjust the crystal field; thus, the luminous intensity was improved by 2.07 times and T50 was increased from 380 K to 453 K. Due to the Sr2+ ion doping, some of the Eu3+ ions cannot be reduced and remain in the trivalent state. In addition, by integrating the as-prepared Ba1.42Sr2.5La6O(SiO4)6:Eu phosphor, commercial blue and red phosphors, and a 385 nm LED chip, a white-LED lamp was made, which realized an applicable color rendering index (Ra = 94.6). For the Ba0.42Sr3.5La6O(SiO4)6 phosphor, the emission can be shifted from yellow to green and to yellow by excitation wavelength variation from 250 to 360 and 480 nm, which proves that the phosphor is a promising candidate for anti-counterfeiting applications.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
·
2022
·Vol. 97
·期 8
·2055-2067
·
IF 3.709
Xiaolong Liu,Jingye Ma,Minxin Wang,Hong Yuan
BACKGROUND A series of mesoporous Pt@KIT−6/SAPO−11 catalysts with SiO 2 :Al 2 O 3 molar ratios of 0.3, 0.4, or 0.5 and Pt loadings of 0.4, 0.8, or 1.2 wt% were prepared via an in situ encapsulation process using a PEO − PPO − PEO triblock copolymer (EO 20 PO 70 EO 20 , P123) as the mes. China 750001 oporous template and KIT−6 molecular sieves as the silicon source. RESULTS These catalysts were characterized by transmission electron microscopy (TEM), specific surface area analysis, and pyridine–infrared spectroscopy (Py − IR). The results showed that Pt nanoparticles with particle sizes of 3–7 nm were uniformly dispersed on the supports. These materials also exhibited good mesoporous structures with specific surface areas of 138–197 m 2 /g and average pore sizes of 7.1–9.9 nm. The specimens having a SiO 2 :Al 2 O 3 molar ratio of 0.4 also showed an orderly strip−shaped pore structure. The Py − IR results indicated that the catalysts had both Brønsted acid and Lewis acid sites, with total acid contents in the range of 77.8–131.1 μmol/g. CONCLUSION The decarboxylation of oleic acid using these materials under CO 2 was examined. The catalyst with a SiO 2 :Al 2 O 3 molar ratio of 0.4 and a Pt loading of 0.8 exhibited the best catalytic performance and a C8 − C17 alkanes yield as high as 85.1% at 340 °C by using a catalyst−to−oil mass ratio of 1:10 and a reaction time of 5 h. This performance was attributed to the ordered mesoporous structure of this catalyst along with its high surface area (173 m 2 /g), good crystallinity (92.8%), suitable acid content (98.6 μmol/g), and abundant Pt metal active sites. © 2022 Society of Chemical Industry (SCI).
✓ 已验证
产品关联
DOI
高影响因子
SOLVENT EXTRACTION AND ION EXCHANGE
·
2022
·
IF 3.695
Huifang Xing,Liangrong Yang,Lu Wang,Mengfang Li,Jiemiao Yu,Diannan Lu,Gang Ye,Huizhou Liu
The effect of ion species and concentration on the extraction percent of Cs+ by 1,3-Diisopropoxycalix [4] arenecrown-6 (BPC6) in octanol/water solvent extraction system has been studied by molecular dynamics simulations and experiments. The results show that the anionic species play an important role on the enhancement of the extraction percent of Cs+. Specifically, the order in which anions promote the extraction percent is different at different total anion concentrations. At a relatively low anion concentration of 0.5 M, the extraction percent follows the sequence: ClO4−> I−> NO3−> Br−> Cl−> SO42−> F−. At a relatively high concentration of 2 M, the extraction percent of Cs+ follows the following sequence: I−> ClO4−> Br−~ NO3−> Cl−> SO42−> F−. It is indicated that the extraction percent is dominated by the anion’s interface propensity, which is the probability of anion distribution in the interface compared to the water phase. However, at low concentration of anions, strong coordination effect of NO3− promotes the extraction effect compared to Br−. At the high anion’s concentration, the stronger salting-out capacity of Br− leads to a considerable increase of extraction percent. In addition, the cations also slightly affect the extraction percent. The extraction percent is affected by both cations’ concentration and the salt-out effect. On this basis, a neutral Cs+ extraction system has been established, and one stage extraction percent could reach 62.5%.
✓ 已验证
产品关联
DOI
高影响因子
BIOMEDICAL CHROMATOGRAPHY
·
2022
·Vol. 36
·期 10
·e5435
·
IF 1.911
Jing Zhang,Jun-qing Yang,Ying Luo,Jian-sha Li,Tao Gong,Su-qiong Huang,Yan Xiong,Xin-hui Jiang
The study of brain diseases has long been of interest to researchers worldwide, and stroke is the third leading cause of death that threatens human health. At the same time, cerebral ischemia–reperfusion injury is closely associated with high rates of disability and mortality. The conditions of the 6-aminoquinolyl N -hydroxysccinimidyl carbamate method for the derivatization of amino acids in the bone marrow fluid and hippocampus of C57BL/6 mice with cerebral ischemia–reperfusion injury were explored and optimized, such as the column temperature, concentration of derivatization reagents and mobile phase concentration. The mobile phase consisted of 20 m m sodium acetate solution (phosphoric acid to adjust pH 5.0) and 60% acetonitrile solution at a flow rate of 1 ml min −1 . The 23 analytes were separated and determined in a gradient elution procedure; the correlation coefficient r was >0.9990 in the range 0.1–8.0 μg ml −1 . The results showed that the content of relevant analytes was significantly changed in the cerebral ischemia–reperfusion injury model, and the method was suitable for the simultaneous determination of 23 amino acids in the bone marrow fluid and hippocampus of C57BL/6 mice.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）