MICROCHIMICA ACTA
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2025
·Vol. 192
·期 9
·1-13
·
IF 5.3
Kang Jia,Qi Meng,Wang Yasen,Li Linchun,Zhou Xinda,An Xiaoshuo,Hammock Bruce D.,Zhang Jinlin,Huo Jingqian
Nanobodies specifically recognizing atrazine were successfully obtained through immunization of alpacas and phage display libraries, and an indirect competitive immunoassay (ic-ELISA) based on nanobodies was constructed with an IC 50 of 0.062 μg/mL and a minimum detection limit of 0.01 μg/mL. An Au@PtNPs with excellent colorimetric performance, high catalytic activity, and high stability was synthesized. The combination of Au@PtNPs and nanobodies led to the development of a direct competitive immunoassay (dc-ELISA) with higher specificity, convenience, lower cost and an IC 50 value of 0.032 μg/mL which was lower than the ic-ELISA. Based on the Au@PtNPs and nanobodies, a novel LFIA model for qualitative and semi-quantitative detection of atrazine was constructed with a visual detection limit of 5 ng/mL. The present study is of great significance for the construction of atrazine immunoassay combining nanobodies and nanoenzymes, which provides a sensitive, specific, simple and reliable method for the detection of atrazine in the environment.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Xiaoxiao Dong,Chang Lu,Shuaijie Guo,Siqi Zhang,Xuelian Hu,Wenliu Wang,Yiwei Tang,Shuo Wang,Xiuying Liu
A magnetic NiFe 2 O 4 @TiO 2 @Au composite was successfully synthesized via layer-by-layer assembly approach and exhibited excellent SERS performance. The composite was functionalized with an aptamer modified with Cy3, serving as the Raman signal reporter, and was hybridized with complementary DNA oligonucleotides (cDNA) to construct the NiFe 2 O 4 @TiO 2 @Au@ssDNA SERS aptasensor. This aptasensor enabled the development of a sensitive, specific, and straightforward SERS assay for acetamiprid detection, exhibiting good accuracy. Under optimized conditions, an inverse correlation was established between the acetamiprid concentration and the Raman intensity at the characteristic peak of 1132 cm −1 , spanning a range of 10 −1 -10 4 nmol/L with a LOD of 8.4 × 10 −1 pmol/L. Standard addition experiments to three types of leafy vegetables samples yielded recoveries ranging from 94.30 % to 111.83 %, with a relative standard deviation of <5.56 %. This method shows potential for detecting other hazardous substances in food and environmental samples by simply changing the corresponding aptamers and cDNA.
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RUSSIAN JOURNAL OF ELECTROCHEMISTRY
·
2025
·Vol. 61
·期 5
·189-197
·
IF 0.8
Yunxia He,Chen Jianlei,Zhang Tianruo,Liu Yang,Wang Qingkui,Qu Keming,Cui Zhengguo
We have developed an electrochemical sensor for the rapid detection of nitrofurazone (NFZ) in aquaculture seawater, utilizing a glassy carbon electrode (GCE) modified with Au nanoparticles (AuNPs). Compared to the unmodified electrode, the modified electrode exhibited higher electrocatalytic activity than the GCE and could be used efficiently for the detection of NFZ. It was found that the AuNPs modified electrode exhibited a higher specific surface area, as determined by scanning electron microscopy characterization. The effects of various parameters, including the number of electrodeposition cycles for modified electrode preparation and the pH of the electrolyte for NFZ detection were optimized. Under optimized experimental conditions, the peak current and concentration of NFZ exhibited a linear relationship in the range of 3 to 100 μM when analyzed using square wave voltammetry (SWV), with a limit of detection of 0.24 μM. The proposed sensor was successfully utilized for the detection of NFZ in aquaculture seawater. The spiked recoveries ranged from 96.35 to 107% (RSD < 4.13%), indicating that the method demonstrates satisfactory accuracy and performance for detecting NFZ in real seawater.
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INORGANIC CHEMISTRY
·
2025
·
IF 4.7
Xin Wan,Wensong Wang,Enze Tian,Jun Zhou,Congqiang Long,Fan Liu,Qiao Zhang,Jinxuan Fan,Feipeng Du,Bin Li,Si Chen
Nanomaterials offer enhanced stability and functionality for photothermal agents; however, their efficacy is often limited by suboptimal cellular internalization and photothermal conversion efficiency. To address these challenges, we designed a multicomponent inorganic–organic hybrid photothermal agent that integrates a virus-mimicking morphology and stimuli-responsive components. Gold nanostars (GNS) were functionalized with a pH-responsive epigallocatechin gallate (EGCG) polyphenol network, followed by in situ growth of CuS, yielding star-shaped GEC nanoassemblies with a rough surface. This biomimetic design leverages (i) the plasmonic photothermal properties of the GNS core, (ii) the acid-triggered disassembly of the EGCG network (mimicking viral protein shells), and (iii) the in situ synthesized CuS layer exhibiting a virus-mimetic rough surface and targeting capability, which enhances near-infrared light absorption and promotes endocytosis by the target cells. The synergistic integration of GNS and CuS significantly enhanced the photothermal conversion efficiency. Under tumor acidic conditions, the EGCG network disintegrated, leading to the shedding of the CuS shell and a reduction in overall size, which facilitated deep tissue penetration. Structural characterization confirmed the hierarchical architecture and pH-responsive size transition. Compared to unmodified GNS, the cellular uptake of GEC by 4T1 cells was approximately 4.5-fold higher, attributable to its virus-like rough surface, acid-responsive disintegration, and targeting ability. This work demonstrates a rational biomimetic strategy for engineering stimuli-responsive inorganic–organic hybrids with optimized photothermal performance through biomimetic component engineering.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Xiaomu Shan,Jie Pan,Xuejian Du,Jian Shi,Zhuofan Wei,Yuanze Xu,Shouzhen Jiang
The excellent performance of surface-enhanced Raman spectroscopy (SERS) is closely related to the intensity, density and uniformity of hotspots. In this study, we introduce a PET/Au NPs@COF Raman substrate featuring three-dimensional hotspots. The spacing between each layer of gold nanoparticles (NPs) is precisely controlled by adjusting the thickness of the COF via the interfacial synthesis technique, causing the strong coupling between gold particles across the layers. The porosity of the COF enables the substrate to adsorb numerous analyte molecules into the large-area uniform hotspots. Through simulations and adsorption detection on the substrate, Raman testing further demonstrated that the substrate with double-layer Au NPs@COF exhibited the most favorable SERS performance. Additionally, the substrate allows for selective detection based on the particle size of the target molecule. The flexibility of the substrate enables it to conform to irregular surfaces, effectively capturing analytes from a variety of real samples.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yahui Ji,Nana You,Xiaoping Hu,Fei Wang,Gen Liu
The environmental hazards posed by bisphenol A (BPA) have become a critical global concern. Consequently, the development of rapid, user-friendly, and highly sensitive methods for BPA detection is essential for pollution control and health risk assessment. In this study, a novel electrochemiluminescent (ECL) sensor was designed using Ru(bpy) 3 2+ -encapsulated Zn-based metal–organic frameworks (Ru-ZnMOF) integrated with gold nanoparticles (Au@Ru-ZnMOF) as efficient ECL probes. Notably, BPA caused a significant quenching effect on the ECL signal of Au@Ru-ZnMOF in the presence of tripropylamine (TPA) as a coreactant. Under optimized experimental conditions, a glassy carbon electrode modified with Au@Ru-ZnMOF (glassy carbon electrode (GCE/Au@Ru-ZnMOF) demonstrated exceptional ECL performance for BPA detection, with a broad linear detection range (1.0 × 10 −9 to 5.0 × 10 −4 mol·L −1 ) and an ultra-low detection limit of 2.5 × 10 −11 mol·L −1 . The proposed sensor was successfully applied for the quantification of BPA in thermal paper samples, achieving recovery rates between 95.8 % and 98.5 %, confirming its high accuracy and reliability.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Weilin Zhong,Chao Wang,Hailun Zhao,Suqing Peng,Zhipeng Tian,Riyang Shu,Ying Chen
Constructing efficient photothermal catalysts and understanding their photothermal synergistic effects for solar-driven conversion of biomass derivatives towards clean energy carriers are essential in the development of renewable energy and waste disposal. In this study, Au nanoparticles loaded on TiO 2 nanoflakes were synthesized as photothermal catalysts for bio-derived glycerol photothermal reforming hydrogen production. The results found that the generation of photogenerated carriers is a crucial process in the photothermal reforming of glycerol. In particular, the hot electrons excited by plasmonic Au nanoparticles did not participate in the hydrogen production reaction through neither direct nor indirect transfer. Instead, the hot carriers promoted the intermolecular collisions between reactants through thermalization. In addition, such generated local heat could reduce the semiconductor impedance and improve the migration efficiency of photogenerated carriers, resulting in an efficient conversion of gas phase intermediates. As obtained, photothermal enhanced reforming can improve hydrogen yield by 58%, while the hydrogen generated constant and the absorption equilibrium constant was calculated as 2.38 mmol∙g −1 ∙h −1 and 7.00 mL∙mmol −1 .
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2016
·Vol. 28
·期 5
·4138-4145
·
IF 1.798
Yu Mei,Meng Yanbing,Zhang Jindan,Liu Jianhua,Li Songmei
Super helical Au/TiO 2 nanocomposites were synthesized using plasmid DNA and incorporated into photoanode of dye-sensitized solar cells (DSSCs). The performance of photoanode films and DSSCs was investigated. Plasmid DNA can not only support as bio scaffold to synthesize Au/TiO 2 nanocomposites, but also act as an effective reducing agent under ultraviolet (UV) irradiation. Compared with TiO 2 -only DSSCs, the light harvesting (LH), corresponding photocurrent and power conversion efficiency (PCE) of DSSCs were enhanced by incorporating of mechanically mixed Au-TiO 2 NPs and Au/TiO 2 nanocomposites. Compared to the TiO 2 -only DSSCs samples (5.12%), the PCE of DSSCs with mechanically mixed Au-TiO 2 nanoparticles (NPs) (6.41%) increased by 25.20%, and DSSCs with Au/TiO 2 nanocomposites (8.17%) increased by 59.57%. The best PCE (8.24%) of DSSCs was obtained with the incorporation of Au/TiO 2 nanocomposites. Two reasons were presented for the best performance of DSSCs with Au/TiO 2 nanocomposites. Firstly, the localized surface plasmon resonance (LSPR) effect of Au NPs enhanced the absorption visible light. Secondly, the super helical structure of Au/TiO 2 nanocomposites provided a path for the transmission of photoelectrons.
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CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Zizhen Yu,Li Jiang,Rongyang Liu,Weidan Zhao,Ziheng Yang,Jinyao Zhang,Shangzhong Jin
The emergence of antibiotic-resistant bacterial strains has caused bacterial infections to become a more serious worldwide health problem. The development of multi-functional platform that can quickly and sensitively detect bacteria and effectively inhibit or kill bacterial is important and urgent. Herein, a novel versatile MXene-Au nanocomposite was successfully synthesized by self-assembly method for rapid detection of bacteria and photothermal sterilization. The typical gram-negative Escherichia coli (E. coli) and the gram-positive Bacillus subtilis (B. subtilis) were used as models to perform label-free, rapid and sensitive detection of bacteria based on SERS method. The antibacterial performance of the material was proved by the colony counting method, and the survival rates of E. coli and B. subtilis were as low as 8.05% and 0.06%, respectively. The Ti 3 C 2 T x -Au nanoparticles (NPs) irradiated with 808 nm light showed significant antibacterial effect within only 6 min, and the germicidal rates for E. coli and B. subtilis were 99.25% and 100%, respectively. The photothermal conversion efficiency reached as high as 43.40%. Accordingly, this multi-functional nanocomposite material can not only detect bacteria sensitively, but also has antibacterial and photothermal sterilization effects, which provides a greatly promising countermeasure for clinical treatment of diseases caused by multi-drug resistant bacteria.
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Materials Horizons
·
2025
·
IF 10.7
Zhenghuan Yin,Yajun He,Peiyu Huang,Wenjie Ma,Jian Liang,Tianyi Wang,Yuhao Peng,Wei Xiao,Dong Gu
Formaldehyde (HCHO) is a major indoor air pollutant that poses serious risks to human health, making its efficient removal a critical environmental concern. Catalytic oxidation at room and sub-ambient temperatures has attracted significant attention due to its potential to completely decompose HCHO into harmless CO2 and H2O. However, practical implementation remains challenging because of low reaction activation energy and limited catalyst performance at reduced temperatures. In this study, Au-loaded manganese oxide nanowire catalysts (x% Au/MnO2-NWs) were synthesized using a colloidal deposition strategy to achieve efficient HCHO removal under ambient and sub-ambient conditions. The optimized 1% Au/MnO2-NWs catalyst achieved complete conversion of 280 ppm HCHO at 30 °C and, remarkably, fully oxidized 20 ppm HCHO even at 0 °C, demonstrating outstanding low-temperature activity and practical potential. Comprehensive characterization studies including H2-TPR, EPR, Raman spectroscopy, and in situ DRIFTS revealed that Au nanoparticles induced abundant oxygen vacancies, which acted as active sites for HCHO adsorption and promoted O2 activation. The synergistic interaction between Au and MnO2 significantly enhanced low-temperature catalytic performance, providing mechanistic insights and a solid foundation for the rational design of highly efficient catalysts for indoor formaldehyde removal.
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CRYSTENGCOMM
·
2025
·
IF 2.6
hanchi Ma,Hao Wang,Xiya Yan,Bin Liu,Jianhui Yang
Au@Pd@Pt core-shell nanoparticles (CSNs) with mesoporous structures and nanocavities were synthesized through a seed-mediated growth method. The process involved the initial formation of Au@Pd CSNs via the reduction of PdCl₄²⁻ by ascorbic acid (VC), followed by a reduction of PtCl62- by VC and a galvanic replacement reaction between the Pd shell and PtCl₆²⁻. The galvanic replacement reaction is a critical step in the formation of Au@Pd@Pt CSNs featuring distinctive void in the mesoporous structures. The electrocatalytic performance of the as-synthesized Au@Pd@Pt CSNs for the ethanol oxidation reaction (EOR) was systematically evaluated. Due to the unique hierarchical structure featuring both mesoporosity and internal nanocavities, the Au@Pd@Pt CSNs exhibited significantly enhanced electrocatalytic activity compared to Au@Pd CSNs, Au@Pt CSNs, and commercial Pd/C catalysts. This work presents a facile strategy for constructing hierarchical core-shell nanostructures, demonstrating considerable potential for application in electrocatalytic ethanol oxidation.
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International Journal of Electrochemical Science
·
2023
·
IF 1.5
Na Li,Changhong Wang,Tingzhen Li,Brendan Latimer,Zhen Liu,Zhenghua Tang
Bimetallic nanoparticles with core-shell structure usually demonstrate enhanced catalytic performance due to the lattice strain created between the core and the shell region. The Au@Ag core-shell nanoparticles with different Au-to-Ag molar ratios were firstly fabricated by a facile method under mild conditions, and the n(Au): n(Ag) = 1: 2 sample showed the best electrocatalytic activity toward oxygen reduction reaction (ORR), a key reaction which plays an important role in fuel cells and metal-air batteries. Subsequently, the Au@Ag nanoparticles of n(Au): n(Ag) = 1: 2 were loaded on carbon nanotubes to prepare nanocomposite catalysts with different metal mass ratios of 20% Au@Ag/CNTs, 30% Au@Ag/CNTs, 40% Au@Ag/CNTs, and 50% Au@Ag/CNTs. The characteristics of the as-synthesized nanocomposites were examined by transmission electron microscopy (TEM), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) as well. The nanocomposites demonstrated effective electrocatalytic performance toward ORR. Electrochemical tests showed that the 30% Au@Ag/CNTs sample exhibited the highest activity among the series, in aspects of onset potential and kinetic current density. Furthermore, the sample of 30% Au@Ag/CNTs exhibited markedly higher long-term stability than Pt/C. The results clearly illustrate that the Au@Ag core-shell nanoparticles-based nanocomposites hold great potentials as efficient ORR catalysts for fuel cell applications.
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