Biomed Research International
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2017
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IF 2.476
Li Lv,Chunxia Liu,Zhengrong Li,Fangming Song,Guocheng Li,Xingzhen Huang
The purpose of this study was to evaluate the potential of micelle to change the pharmacokinetics of quercetin (QUT), with a primary goal of enhancing its oral bioavailability. QUT-loaded methoxy poly(ethylene glycol)--poly(L-lactic acid) micelle (QUT-loaded MPEG--PLLA micelle) was prepared by a thin-film hydration method, resulting in a particle size of 88.5 nm. A liquid chromatography tandem-mass spectrometry (LC-MS/MS) method was developed and validated for determination of QUT in rat plasma. The chromatographic separation was performed on an Agilent Eclipse-C18 (4.6 mm 50 mm, 3.5 m) with an isocratic mobile phase system consisting of water and methanol (, ) at a flow rate of 0.4 mL/min. Calibration curves were linear over the concentration ranges of 2.5–2000 ng/mL for QUT. The micelle was orally administered at a single does in rats, and the pharmacokinetic parameters were evaluated and compared with that administered with the QUT aqueous suspension. The results show that the micelle was able to increase the QUT’s oral bioavailability 9-fold compared to the QUT aqueous suspension. These results suggest that methoxy poly(ethylene glycol)--poly(L-lactic acid) is a potential carrier for the oral delivery of QUT.
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International Journal of Nanomedicine
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2013
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IF 3.463
Gaobo Long,Xiao-lan Yang,Yi Zhang,Jun Pu,Lin Liu,Hong-bo Liu,Yuan-li Li,Fei Liao
Purpose Magnetic submicron particles (MSPs) are pivotal biomaterials for magnetic separations in bioanalyses, but their preparation remains a technical challenge. In this report, a facile one-step coating approach to MSPs suitable for magnetic separations was investigated.Methods Polyethylene glycol) (PEG) was derived into PEG-bis-(maleic monoester) and maleic monoester-PEG-succinic monoester as the monomers. Magnetofluids were prepared via chemical co-precipitation and dispersion with the monomers. MSPs were prepared via one-step coating of magnetofluids in a water-in-oil microemulsion system of aerosol-OT and heptane by radical co-polymerization of such monomers.Results The resulting MSPs contained abundant carboxyl groups, exhibited negligible nonspecific adsorption of common substances and excellent suspension stability, appeared as irregular particles by electronic microscopy, and had submicron sizes of broad distribution by laser scattering. Saturation magnetizations and average particle sizes were affected mainly by the quantities of monomers used for coating magnetofluids, and steric hindrance around carboxyl groups was alleviated by the use of longer monomers of one polymerizable bond for coating. After optimizations, MSPs bearing saturation magnetizations over 46 emu/g, average sizes of 0.32 μm, and titrated carboxyl groups of about 0.21 mmol/g were obtained. After the activation of carboxyl groups on MSPs into N-hydroxysuccinimide ester, biotin was immobilized on MSPs and the resulting biotin-functionalized MSPs isolated the conjugate of streptavidin and alkaline phosphatase at about 2.1 mg/g MSPs; streptavidin was immobilized at about 10 mg/g MSPs and retained 81% ± 18% (n = 5) of the specific activity of the free form.Conclusion The facile approach effectively prepares MSPs for magnetic separations.
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ADVANCED POWDER TECHNOLOGY
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2022
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IF 4.969
Zhiwei Wang,Mingqiang Cheng,Jiaojiao Bu,Lei Cheng,Juanjian Ru,Yixin Hua,Ding Wang
Tin is one of the vital substances in the material and chemical industry. Deep eutectic solvent (DES) possesses excellent physicochemical properties for metal preparation. In this study, the electrochemical behavior of Sn(II) and metallic tin preparation in choline chloride-ethylene glycol (ChCl-EG) DES were investigated. Linear sweep voltammetry is carried out to study the effects of substrate material (Ni, Cu, Pt, C, Fe, Al, W, glassy carbon (GC) and Ti), temperature (313–353 K) and SnCl 2 concentration (10–100 mM) on the electrochemical behavior of Sn(II)/Sn. Results demonstrate that metallic tin is easier to be prepared on the Ni electrode, and increasing temperature and SnCl 2 concentration both facilitate the reduction of Sn(II). Electrospray ionization mass spectrometry (ESI-MS) shows that the main form of Sn(II) is [SnCl 3 ] - . Chronoamperometric tests indicate that with the increase of applied potential, the nucleation of Sn(II) on the nickel electrode becomes close to the instantaneous nucleation. Simultaneously, the nucleation rate and the number of active sites on the electrode surface increase significantly. Pure tin with a dendritic structure could be prepared with higher current efficiency of 96.4% and lower energy consumption of 320.5 kW·h·t −1 without any additives. All these studies provide a fundamental basis for the preparation of tin powders in ChCl-EG DES.
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Scientific Reports
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2020
·Vol. 10
·期 1
·1-9
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IF 3.998
Meng Xianglong,Zhou Pin,Li Lu,Liu Lizhong,Guo Mingming,Sun Tonghua
The selectivity of a facile reductive and extractive desulfurization process was studied. In this desulfurization method, polyethylene glycol was used as the extractant, and sodium borohydride was used as the reductant. Several different simulated fuels were prepared by dissolving thiophenic sulfides, methylbenzene and hexylene in octane. The results showed that methylbenzene and olefins had different effects on different sulfur compounds during this desulfurization process. The extraction and reduction mechanisms were also explained. Four factors could affect the desulfurization performance: (1) intermolecular hydrogen bonding: (a) active O bonding with aromatic H or (b) S bonding with H atoms in hydroxide radicals, (2) “like-dissolves-like” interactions between polyethylene glycol and thiophenic sulfides, (3) the methyl steric hindrance effect and the electron density of sulfur atoms, and (4) the combination of S atoms with produced nickel boride to form active desulfurization centres. The desulfurization reaction path was also deduced according to the GC/MS results.
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Journal of Energy Storage
·
2025
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IF 9.8
Peiyuan Li,Xinquan Zou,Yuwei Feng,Jiangfeng Luo,Shuolei Ma,Jianxiong Wang,Weihong Guo,Jikui Wang
Phase change materials (PCMs) are widely used in thermal energy storage and temperature regulation due to their ability to absorb and release latent heat during phase transitions. However, conventional PCMs often suffer from leakage and low thermal conductivity, which significantly limits their practical applications. Although polymer networks have been employed to encapsulate PCMs, challenges such as lack of functional modification, complex processing steps and high production costs still need to be resolved. We presented a strategy for synthesizing a double-network composite phase change material through the in situ self-assembly of graphene oxide (GO) within a sodium alginate (SA) matrix, combined with ionic crosslinking between SA and Ca 2+ , resulting in a reduced graphene oxide/calcium alginate/polyethylene glycol (RGO/CA/PEG) composite phase change material. CA imparted good dispersibility to RGO under the premise of effective encapsulation of PEG, and reduced the pressure of RGO encapsulation, resulting in a significant reduction in the preparation cost of the material. The results show that the RGO/CA/PEG has a high energy storage density (145.54 J/g) and can be maintained at 70 °C for 6 h without any leakage. Meanwhile, the construction of the RGO/CA double network enabled the PEG to have good thermal conductivity (127.78 % improvement over pure PEG) and photothermal conversion (85.54 %). The above studies show that the material has good application prospects for solar energy harvesting, battery thermal management, and thermal energy storage.
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CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Jiuli Chang,Lili Wang,Zhanqiang Hu,Songsong Zhi,Dapeng Wu,Kai Jiang,Zhiyong Gao
Selective ethylene glycol oxidation reaction (EGOR) to specific C2 species offers a promising approach to pair with cathodic hydrogen evolution reaction (HER) for electrochemical upcycling of waste polyethylene terephthalate (PET) plastic into high-value chemicals and H 2 . Efficient catalyst with tailored adsorptive interaction strength with intermediates is pivotal to fulfill such a scenario. Herein, a self-supported PdNi/NF electrode with deposition of PdNi hybrid onto nickel foam (NF) substrate was prepared by a gentle replacement reaction, which demonstrated high catalytic activity for EGOR toward glycolate with high faradaic efficiency (90 ± 2 %), decent yield (0.7 ± 0.01 mmol h −1 cm −2 ) and acceptable stability at a low applied potential of 0.8 V, which enabled electrosynthesis of glycolate via electrooxidation of PET hydrolysate. Meanwhile, a self-supported Cu, Co bimetallic phosphide onto NF substrate (CuCoP/NF) was prepared for HER catalysis, which featured a low overpotential of 117 mV at cathodic current density ( J ) of −100 mA cm −2 and decent durability. The further pairing of anodic EGOR and cathodic HER enabled electrolysis of PET hydrolysate to coproduce glycolate and H 2 at an energy-saving manner. This work provides a viable paradigm for coproduction of glycolate and H 2 from electrochemical upcycling of PET plastic, and presents essential instruction for reclamation of obsolete resource via sustainable and waste-to-treasure manner.
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EUROPEAN POLYMER JOURNAL
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2025
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IF 6.3
Yingying Li,Yali Liu,Ai Liu,Changjie Xu,Chijian Zhang,Jianyong Yu,Ruchao Yuan,Faxue Li
Introducing the renewable poly(trimethylene ether glycol) (PO3G) as soft segments into bio-based poly(propylene terephthalate) (PTT), which is synthesized from the bio-based propylene glycol (PDO) monomer, results in thermoplastic polyester elastomers (PTT-PO3G) with superior thermomechanical properties. As the PO3G content in PTT-PO3G copolymers increased from 20 wt% to 60 wt%, the melting temperatures of these copolymers decreased from 220 to 174°C, and the tensile strength decreased from 31.7 to 4.2 MPa with the Shore hardness falling from 60 to 26 D, whereas the elongation at break showed an increase tendency from 697 % to 1074 %. Characterizations utilizing dynamic thermomechanical analysis (DMA), small angle X-ray scattering (SAXS), and atomic force microscopy (AFM) revealed the presence of microphase separations in PTT-PO3G copolymers. The strength and moisture regain of PTT-PO3G-20 elastic fibers fabricated via an eco-friendly melt spinning technique reach 1.42 cN/dtex and 1.52 %, which are 58 % and 407 % higher than those of traditional wet-spun Spandex® fibers, respectively. Surprisedly, the resilience of PTT-PO3G-20 fibers exceeded 96 % at an elongation of 20 %, demonstrating its promising potential as a sustainable alternative to Spandex® fibers in textile applications. The excellent thermodynamic properties indicate that the bio-based PTT-PO3G copolymers have great potential to replace traditional petroleum-based elastomers for promoting the sustainable and low-carbon global development.
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JOURNAL OF MATERIALS SCIENCE
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2018
·Vol. 53
·期 18
·13067-13080
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IF 2.993
Zhang Xiaoguang,Qiao Jiaxin,Zhang Weiyi,Cheng Fei,Yin Zhaoyu,Huang Zhaohui,Min Xin
An innovative way to enhance the thermal conductivity of composite phase change materials (PCMs) is by carbonizing the carbohydrate-coated mineral substrate to modify its porous structure. Here, we study the effect of introducing different amounts of carbonized starch acting as a filler for enhancing the thermal conductivity of the shape-stabilized composite PCMs (ss-CPCMs) based on polyethylene glycol (PEG) and modified expanded vermiculite (MEV). The experimental exploration of the thermal behavior of composite PCMs has been explored sufficiently in depth. The MEV is shown by SEM images to tightly adhere to the carbon layer and to be composed of a dense micropore structure. Results from DSC indicate that the latent heat of the PEG/MEV ss-CPCMs gradually decreases with the increase of carbon layer mass fraction. Results obtained from FT-IR and TGA show that PEG/MEV ss-CPCMs exhibit good chemical and thermal stabilities. The thermal conductivity of the PEG/MEV ss-CPCMs increases with the carbon layer mass fractions and reaches up to 1.94 times that of PEG/EV ss-CPCMs. The PEG/MEV ss-CPCMs result in a promising material for applications in energy-efficient buildings due to its excellent thermal properties, ideal thermal conductivity and good chemical and thermal stability.
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CARBOHYDRATE POLYMERS
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2026
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IF 13.2
Chengzhe Niu,Mingyu Li,Gaofei Pan,Jingwen Lu,Huitao Yu,Xin Ge,Wei Feng
Integrating photothermal conversion, thermal storage, and electromagnetic interference (EMI) shielding into porous foams meets the demand for multifunctional high-performance composites. In this work, a novel composite was developed by intercalating sodium alginate (SA) between MXene and polyethylene glycol (PEG), followed by the fabrication of PEG/MXene/SA hydrogels through hydrogen bonding or coordination with Ca 2+ , Ce 3+ , and La 3+ ions. Following directional freeze-drying, a porous foam material with a unique sandwich-structured microstructure was obtained. This material demonstrates excellent shape stability. The composite material with 90% PEG content achieves a high latent heat value of up to 165.47 J/g and a relative latent heat efficiency of 97.17%, demonstrating exceptional dynamic temperature regulation capability. Its photothermal conversion efficiency reaches a maximum of 93.35%. Excellent electromagnetic interference (EMI) shielding performance is exhibited by the composite material at PEG loadings up to 50%. Across the 8.2–12.4 GHz frequency band, the SM@P3-H (with 30% PEG content) and SM@P5-H (with 50% PEG content) samples achieve total shielding effectiveness (SET) values exceeding 70 dB, with maximum values reaching 86.47 dB and 76.51 dB. Owing to its outstanding performance, this composite material demonstrates promising potential for application in thermal management and electromagnetic protection of electronic devices.
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CHEMICAL ENGINEERING JOURNAL
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2026
·
IF 12.5
Yu Zhang,Yuting Jiang,Yunsheng Xu,Pengwu Xu,Wenjun Peng,Weijun Yang,Shuangfei Xiang,Xianming Zhang
Soft iontronic materials are highly desirable for flexible electronics that operate under deformation and temperature fluctuations, yet practical platforms that combine solid state ionic transport, mechanical robustness, and reprocessability while integrating multiple responsive functions remain limited. Here, a series of X-PEG networks is constructed by integrating acylurea based dynamic covalent linkages, semicrystalline poly(ethylene glycol) segments, and a homogeneously dispersed imidazolium ionic liquid phase. This architecture couples dynamic exchange, associative reinforcement, and reversible crystallinity within one matrix, enabling microstructure governed regulation of mechanics and ion transport. A broad mechanical window is achieved across compositions, with high stretchability and useful strength retained at representative formulations, while ionic conduction is maintained in the 10 −3 to 10 −2 mS·cm −1 range. Robust electromechanical coupling is demonstrated by smooth and repeatable resistance outputs under bending and subtle physiological motions, together with stable cycling performance. Rapid thermal following and heat triggered shape regulation are enabled through PEG crystallization and melting coordinated with relaxation of hydrogen bonded hard domains. Notably, heating produces a resistance decrease that supports temperature triggered circuit warning, consistent with thermally driven microphase reconstruction, primarily through the melting of crystalline domains, which improves the effective connectivity of ion-conducting pathways. The networks are melt-reprocessable, and ionic conductivity as well as strain and temperature responsive sensing outputs are largely preserved after repeated hot pressing cycles. This work establishes a recyclable ionic network platform in which dynamic bonding and semicrystalline switching jointly program microstructure and function, offering a practical materials strategy for sustainable soft iontronic devices.
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ANALYTICAL LETTERS
·
2026
·
IF 1.8
Xuanying Lu,Xun Li,Xueqi Liu,Dongbin Qian,Liang Lu
Fast detection of trace heavy metals in aqueous media using the laser-induced breakdown spectroscopy (LIBS) technique is of critical importance because of their potential environmental and health risks. Among various strategies for liquid LIBS analysis, the dried droplet method has been widely adopted. However, the coffee-ring effect (CRE) remains a major obstacle to uniform LIBS signal distribution and accurate quantification of target elements. This work proposes a simple and rapid pretreatment strategy to control the deposition morphology of droplets on graphite substrates by adding polyethylene glycol 400 (PEG 400) to suppress the CRE. Experiments demonstrate that adding a PEG 400 mass fraction of 0.5% significantly improves deposition uniformity. Based on this optimized method, LIBS determination of trace cobalt (Co) and strontium (Sr) achieved limits of detection (LODs) of 1.46 and 0.091 mg/L, respectively. Compared to the PEG 400-free condition, the LODs improved by factors of 3.05 for Co and 2.42 for Sr, while the average relative standard deviations decreased from 38.74% to 9.04% for Co and from 32.58% to 10.47% for Sr. These results demonstrate that PEG 400-assisted modulation of droplet evaporation effectively suppresses the CRE, enhancing LIBS-based detection performance for trace metals in aqueous media. The strategy offers a viable solution for environmental monitoring and rapid analysis of industrial effluents.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
·
IF 5.4
Xiaomeng Lu,Wei Zhang
.Polymer-based adhesive with recyclability, thermo-responsivity, universal adhesion prepared via facile ring-opening reaction. • Temperature-regulated adhesion/cohesion balance endows polymer-based adhesive with rapid robust adhesion. • Polymer-based adhesive recycled and reused over five times with well-maintained adhesion in air and underwater. Synthetic polymer-based adhesives have attracted tremendous attention due to their excellent performance during adhesion under dry, wet, and underwater conditions. However, the practical development of such adhesives is hindered by the intricate synthesis of tailored polymers, the inherent challenge of balancing strong adhesion with cohesion, and the prevalent issues of long curing times (typically from tens of minutes to days in the absence of external stimuli). Here, a polymer-based adhesive was synthesized through a facile ring-opening reaction between ethylene glycol diglycidyl ether and aniline. The resulting polymer leverages a backbone rich in hydroxyl and phenyl groups. Heating the polymer-based adhesive to 80 °C for 3 min improves its flowability, promoting intimate contact with the substrate. Subsequent cooling to room temperature restores interactions within the adhesive, resulting in strong cohesion. This dynamic mechanism enables the polymer-based adhesive to achieve impressive adhesion strengths of 4.4 MPa in air and 3.5 MPa underwater on stainless steel. Importantly, the polymer-based adhesive can be recycled and reused over five cycles with well-maintained adhesive strength. This work thus provides a novel and feasible design strategy for next-generation reusable adhesives capable of performing in demanding dry and aqueous scenarios. Download: Download high-res image (245KB) Download: Download full-size image
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危险品化学品经营许可证（带存储）