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FOOD RESEARCH INTERNATIONAL · 2025 · IF 8

Polysaccharide from Ganoderma atrum delay senescence and enhance stress resistance through modulating IIS and MAPK pathway in Caenorhabditis elegans

Jiayan Xie,Mengni Shu,Xinyi Chen,Jianhua Xie,Yi Chen,Xiaobo Hu,Chunchao Nie,Danyan Liu,Qiang Yu

Ganoderma atrum is an edible and medicinal fungi in oriental countries with various bioactivities, such as antioxidant, anti-inflammatory and anti-aging properties. The study was to evaluate the effects of polysaccharide from Ganoderma atrum (PSG) on lifespan, healthspan (locomotion, pumping, lipofuscin, ROS, chemotaxis and intestinal permeability) and defense system (stress resistance, antioxidant enzymes activities), as well as to investigate its anti-aging mechanism in Caenorhabditis elegans . The findings indicated that PSG prolonged the lifespan (optimal concentration at 400 μg/mL, with an increased average lifespan by 23.10 %) and improved senescence-related physiological indicators of worms. Furthermore, the lipid accumulation was reduced, while stress resistance and antioxidant enzymes activities were enhanced after PSG intervention. Meanwhile, studies with mutants demonstrated that DAF-16/FOXO and SKN-1/Nrf-2 were required for lifespan-extension, which might be attributed to the IIS and MAPK pathways. Overall, these demonstrated that PSG was a potential dietary supplement to promote health and ameliorate aging-associated pathologies.

✓ 已验证 产品关联 DOI PubMed 高影响因子
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INORGANIC CHEMISTRY COMMUNICATIONS · 2025 · IF 5.4

Simple synthesis of fluorine-doped carbon quantum dots for fluorescence-based Amaranth quantification in food matrices

Xiaofang Tian,Meijie Xie,Xinyu Luo,Boyan Zheng,Yongxia Ao,Jiaxin Liu,Mei Wang,Qianchun Zhang,Yun Wu

The detection of food pigments is essential for ensuring food quality and safety. This study presents the efficient preparation of fluorine-doped carbon quantum dots (F-CQDs) through a simple solvothermal reaction using Zanthoxylum and NH 4 F as precursors. The resulting F-CQDs displayed optimal fluorescence characteristics, along with a quantum yield of 4.81 %. Notably, the as-prepared F-CQDs exhibited excellent photostability and were effectively quenched by amaranth, demonstrating their potential as reliable probes for amaranth detection. The probe showed a strong linear response ( R 2  = 0.9992) to amaranth concentrations of 0.15–75 μM, yielding a limit of detection as low as 50 nM. Validation tests across various food matrices, including bayberry, a sugar-sweetened beverage, and candies, yielded good recovery rates of 89.0 %–119 % and a relative standard deviation of less than 4.9 % ( n  = 5), indicating high reliability. These findings suggest that F-CQDs are viable candidates for detecting amaranth in foods, which can help enhance food safety and quality control.

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SEPARATION AND PURIFICATION TECHNOLOGY · 2025 · IF 9

Ultrahigh-flux 1D metal–organic framework nanowires membranes for selective dye separation

Meipeng Jian,Qi Hong,Xiao Tian,Yuqi Pan,Houkun Wei,Haiyan Li

Low-dimensional metal–organic frameworks (MOFs) have attracted substantial research interest in the field of water treatment. However, the simultaneous realization of ultra-high flux and precise molecular sieving remains a critical challenge. Herein, we report a novel one-dimensional (1D) Ni-MOF nanowires via a solvothermal method. By systematically tuning the reaction temperature, Ni-MOF nanostructures with distinct dimensionalities − including nanosheets (NSs), nanoneedles (NNs), and nanowires (NWs) were successfully prepared. Notably, the Ni-MOF NWs exhibited an exceptional adsorption capacity of 567 mg·g −1 for Brilliant Blue (B.B.), while demonstrating negligible adsorption towards Acid Red 18 (A.R.18). This selective adsorption was attributed to preferential hydrogen bonding and π–π interactions. Benefiting from their high specific surface area and hierarchical porosity, the Ni-MOF NWs were deposited onto cellulose acetate substrates to fabricate membranes with tunable thickness. The optimized 3.0 μm-thick membrane achieved a superior water permeance of 250 LMH·bar −1 and nearly complete (∼ 100 %) rejection of B.B., while allowing A.R.18 to pass through unimpeded. The results of molecular simulation showed that the stacked nanochannels by 1D Ni-MOF NWs   and the strong coordination effect within the Ni-MOF NWs membrane enhanced the dyes separation effect and rejection. Moreover, the membrane maintained 100 % B.B. removal efficiency over 10 regeneration cycles and exhibited an effective antifouling ability, underscoring its outstanding operational stability and recyclability. This work not only introduces a scalable strategy for constructing low-dimensional MOF-based membranes but also offers a promising solution for energy-efficient, high-throughput treatment of dye-containing wastewater.

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CHEMICAL ENGINEERING JOURNAL · 2024 · IF 13.3

Retrievable ultrafast covalent triazine framework membranes for organic solvent nanofiltration

Guiliang Li,Yang Liu,Zhaoyi He,Ke Shi,Fu Liu

Covalent organic frameworks (COF) membranes are considered as promising candidates for organic solvent nanofiltration (OSN) due to their well-defined porosity, high perm-selectivity, and exceptional resistance to solvents. However, irreversible membrane fouling caused by filter cake layers or pore clogging challenges the robust separation over long-term operation especially for well-known COF membranes. Here, we present novel ultrafast covalent triazine frameworks (CTF) membranes with retrievable separation performances for OSN processes. CTF-1 membrane with unitary nanopore and CTF-m membrane with binary nanopore are fabricated via an air-organic solvent interfacial polymerization technique for comparison, which demonstrates molecular-level selectivity (MWCO, ∼320 Da for CTF-1 and ∼ 625 Da for CTF-m) and ultrafast permeability for polar organic solvents. Moreover, the heterogeneous skeleton nanopores structure of CTF-m membranes facilitates efficient separation of photogenerated carriers, thus resulting in retrievable permselectivity. This work offers an efficient strategy via Donor-Acceptor structure modulation to tackle OSN membrane fouling, paving the way for applications of framework membranes.

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FOOD CHEMISTRY · 2024 · IF 8.5

Relatively reliable and rapid identification of colorant compounds in food matrices by HPLC-DAD-QTOF-MS combined with theoretical calculation

Jie Shi,Mingquan Huang,Qiang Yang,Yin Xu,Jihong Wu,Hongqin Liu,Jinglin Zhang,Fuping Zheng,Wei Dong

A new convenient method for identifying colorant compounds (CCs) in food matrices was developed using high-performance liquid chromatography with a diode array detector and quadrupole-time-of-flight mass spectrometer (HPLC-DAD-Q/TOF-MS) combined with theoretical calculations. A model sample containing three typical CCs was completely separated via HPLC-DAD. The obtained 3D ultraviolet-visible (UV–vis) spectra revealed the maximum absorption wavelengths (MAWs) of all CCs (yellow, 430 nm; red, 520 nm; blue, 620 nm) in the range of 400–800 nm, and their colors were determined based on their MAWs. Temporary structures of the CCs were obtained using Q/TOF-MS analysis. Theoretical calculations were then performed to obtain the theoretical MAWs and colors of the CCs according to their calculated UV–vis spectra based on temporary structures. The structures of the CCs were confirmed without the need for authoritative standards by comparing the consistency between their experimental and theoretical MAWs and colors. This method is particularly suitable for identifying CCs or compounds with UV–Vis absorption, including new compounds, compounds for which standards are difficult to obtain, and known compounds without reporting relevant molecular information.

✓ 已验证 产品关联 DOI PubMed 高影响因子
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Science Advances · 2025 ·Vol. 11 ·期 46 · IF 12.5

Bioinspired wettability boundary stabilizes water sloshing

Jie Ma,Zidong Zhan,Zihao Zhang,Zhuoxing Liu,Jia Peng,Cunlong Yu,Lei Jiang,Lei Wu,Zhichao Dong

Liquid sloshing leads to spillage, waste, and operational inefficiency across multiple industries. Although strategies such as baffle designs and foam inserts exist, they often fall short in real-world dynamic conditions. Inspired by liquid-stabilizing mechanisms of pitcher plants and impact-dampening notches of water lilies, we introduce a dual-biomimetic cup design that enhances liquid stabilization using three-dimensional printing to construct structures and superhydrophobic coating for wettability boundary modification. Our system integrates patterned hydrophilic-superhydrophobic boundaries with strategically placed superhydrophobic notches, synergistically stabilizing water surfaces and dissipating oscillatory energy. Comprehensive tests—including centrifugal, vibrational, and real-world transport scenarios—demonstrated a spill rate of approaching 0%, as well as robust resistance to water sloshing. Notably, a four-tier tower of dual-biomimetic cups mounted on a car retained nearly 100% of their liquid after traversing 50 alternating speed bumps, whereas conventional cups lost more than 40%. Our bioinspired method demonstrates a scalable and versatile approach that bridges natural wetting strategies with practical engineering applications in liquid transport and containment.

CAS / MDL: 3844-45-9
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Bioactive Carbohydrates and Dietary Fibre · 2025 · IF 3.6

Protection against intestinal damage in female Drosophila melanogaster: Comparative contribution of arabinoxylan and its non-covalent/covalent complexes with catechin

Dima Atehli,Tianyu Qi,Rui Liu,Wan Wang,Qiaomei Zhu,Yuanlin Sun,Qingbin Guo,Ji Kang

Both arabinoxylan (AX) and catechin (CA) have shown promising therapeutic potential for inflammatory bowel disease (IBD). However, the efficacy of their covalent (S, CP) and non-covalent (PM) complexes against IBD remains largely unexplored. This study evaluated the therapeutic effects of AX, CA, and their respective complexes in a Drosophila melanogaster model of dextran sodium sulfate (DSS)-induced colitis. Results demonstrated that covalent AX-CA complexes generated by ultrasonic treatment provided the greatest therapeutic benefits, followed by those produced using cold plasma treatment. These complexes significantly improved survival rates, restored locomotor activity, enhanced metabolic rate, improved intestinal barrier function, markedly reduced the expression of genes associated with JAK/STAT signaling pathway, and concurrently upregulated the expression of genes within the Nrf2/Keap1 pathway.

CAS / MDL: 3844-45-9
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY · 2025 · IF 6.2

Standardized Synergistic Strategy for Insect Growth Regulators: Incorporation of RNA Pesticides via a Co-Delivery Nanoplatform Achieves High Control Efficacy with Low-Dosage Application

Yunhui Zhang,Qinhong Jiang,Xiaoqian Wu,Xin Qian,Shiheng An,Jie Shen,Jianyu Meng,Shuo Yan

Insect growth regulators (IGRs) face limitations of slow action and high dosage, while RNA pesticides are constrained by the scarcity of effective RNAi targets. Here, we propose a standardized strategy to develop multicomponent nanopesticides by combining IGRs with RNA pesticides via a co-delivery nanoplatform. The star polycation (SPc) nanocarriers and diflubenzuron (DFB) were assembled into nanoscale DFB/SPc complexes, enhancing toxicity against green peach aphids by disrupting chitin biosynthesis. RNA-seq analysis identified chitin synthase (CHS) as a synergistic RNAi target. The hpCHS/SPc complex effectively silenced CHS, inducing more than 50% aphid mortality. Co-loading dsCHS and DFB produced stable nanoparticles with improved leaf adhesion, plant uptake, aphid cuticle contact, and translocation, achieving up to 82.2% mortality at only LC20 of free DFB. This work establishes a generalizable, scalable approach for designing multicomponent nanopesticides with high efficacy and low dosage for sustainable pest control.

CAS / MDL: 15332-10-2 3844-45-9
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JOURNAL OF MEMBRANE SCIENCE · 2025 · IF 9

Molecular welded interface engineering to synthesize covalent organic framework membranes for ultrafast molecular sieving

Junkai Gong,Zhiwei Zhou,Hao Wang,Chuang Lei,Qiangqiang Yang,Xiaoguang Wang,Lu Shao,Yanqiu Zhang

Covalent organic framework (COF)-based membranes exhibit exceptional potential for molecular separation owing to their well-defined nanoporosity, tailorable pore apertures, and high surface-to-volume ratios. However, achieving precise pore-size regulation remains a critical challenge in membrane design. Herein, we report a defect-engineering strategy for COF membranes through in-situ polydopamine (PDA) incorporation during interfacial polymerization. Dopamine undergoes oxidative self-polymerization in the p -phenylenediamine (Pa) aqueous phase, generating PDA that simultaneously reacts with Pa monomers and infiltrates TpPa-COF framework defects via Schiff-base chemistry. This dual-function modification not only repairs structural imperfections, but also introduces hydrophilic moieties that enhance surface wettability. The optimized PDA-TpPa membrane demonstrates superior separation performance, achieving 99 % rejection of organic dyes while maintaining a high water permeance of 117.3 L m −2  h −1 bar −1 . Furthermore, the membrane exhibits considerable permeance towards various organic solvents, notably for n-hexane, which reached as high as 337 L m −2  h −1 bar −1 . This work establishes a novel paradigm for fabricating high-performance COF membranes.

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