INORGANIC CHEMISTRY
·
2026
·
IF 4.7
Chaofeng Zhang,Yinhui Yi,Yong Zhao,Gangbing Zhu
This study prepared UiO-66-NH2 MOFs embedded with Ru-tris(2,2′-bipyridyl)(II) hybrids as a nanozyme (designated as Ru/UiO-66-NH2) to propose a bioenzyme-free homogeneous electrochemical (HEC) sensing strategy for detecting organophosphorus pesticides (OPs). Experimental investigation coupled with density functional theory calculation demonstrated that the Ru incorporation significantly amplifies the peroxidase-like (POD-like) activity of UiO-66-NH2 MOFs and that the Ru/UiO-66-NH2 nanozyme exhibits selective responsiveness to coordinate with the OP molecules. Upon OP exposure, the specifical coordination between OPs and MOF structure effectively inhibits the nanozyme’s activity. Utilizing o-phenylenediamine as the catalytic substrate and glyphosate as a model of OPs, the optimized HEC sensor achieves an extensive linear detection range (0.5–10,000 ng/mL) and a low detection limit of 0.13 ng/mL as well as satisfactory recoveries in the real samples of tomato extract and water. It is expected that this innovative bioenzyme-free HEC sensing strategy represents a promising advancement for practical OP residue analysis with potential applications in various fields.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2026
·
IF 7.6
Muze Han,Jiayi Li,Jinjing Liu,Ronghua Yu,Yifu Zhu,Yujie Huang,Kunkun Tu,Shihang Li
Dust pollution threatens ecological stability and human health, but conventional suppressants suffer from short durability, high water demand, and toxicity. This study developed a bio-inspired bacterial/sodium alginate (SA) hydrogel (BSH) dust suppressant composed of Bacillus mucilaginosus (B.m), SA, and NaHCO3. Its application uses a two-step process: first spraying BSH for physical dust adhesion and then CaCl2 to supply Ca2+ ions. Carbonic anhydrase secreted by B.m catalyzes the hydration of ambient CO2 into CO32–, which reacts with Ca2+ to form CaCO3; NaHCO3 further enhances CO32– availability, promoting stable calcite and dust matrix consolidation. The BSH exhibits favorable interfacial properties: a low surface tension of 31 mN/m and strong wettability, with a contact angle of 60°. The hydrogel suppressant achieves a dust suppression efficiency of up to 99.76%, outperforming conventional formulations, and maintains >95% efficiency over a 7 day wind erosion trial, alongside superior water retention. This scalable, biodegradable hydrogel enables long-term dust mitigation and synergizes with greenhouse gas sequestration, shifting the paradigm from passive dust control to climate-friendly environmental management.
✓ 已验证
产品关联
DOI
高影响因子
ACS Omega
·
2026
·
IF 4.3
Fei Guo,Junfeng Wang,Shuaishuai Zhao,Chuanmin Xiao,Xiaofeng Li,Yanfu Pi,Li Liu
To address the pronounced heterogeneity and preferential water channeling through high-permeability zones in the medium- to high-permeability reservoirs of Block J16, Liaohe Oilfield─factors that constrain recovery and limit the effectiveness of water flooding─this study systematically investigates chemical-flooding strategies for enhanced oil recovery. We conducted a comprehensive characterization of the supplied polymer (L-PAM), surfactant, and pre-cross-linked gel particles (PPG). Using a large-scale, three-dimensional heterogeneous physical model, we compared the displacement performance of a binary composite system (polymer + surfactant) and a heterogeneous composite system (polymer + surfactant + PPG). Experimental results show that L-PAM exhibits satisfactory thermal stability, salt tolerance, and long-term property retention. The binary system attains ultralow interfacial tension, whereas the heterogeneous system markedly enhances viscoelastic characteristics. Oil-displacement experiments indicate that the heterogeneous + binary composite system delivers the best recovery outcome, achieving a final recovery of 77.75%, representing an improvement of approximately 28.7% over conventional water flooding. By effectively plugging high-permeability channels, this system substantially improves sweep efficiency in medium- and low-permeability zones and reduces water cut by up to 36.49%. Monitoring of oil-saturation distribution further confirms that the heterogeneous + binary system promotes fluid diversion and profile modification through physical plugging and flow-path alteration, thereby increasing fluid intake in medium- and low-permeability layers. These findings provide experimental evidence and technical guidance for the design and optimization of chemical-flooding strategies for field application.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2026
·
IF 7.3
Bo Wang,Xinyi Luo,Wenting Guo,Ping Hu,Yong Wang,Guohua Qi,Yongdong Jin
Hydrogen sulfide (H2S) is the third gasotransmitter after nitrogen oxide and carbon monoxide, playing vital roles in physiological controls, such as angiogenesis, vascular homeostasis, thrombosis, inflammation, and remodeling. Monitoring the content level and dynamic variations of H2S within cells will help understand its involvement and relationship in cancer proliferation and may also lead to new cancer therapy options. Herein, we developed a simple and effective approach for ionic rectification sensing detection of H2S in single living cells using p-azidobenzoic acid (PA)-functionalized glass nanopores (PA-nanopores), in which the glass nanopores were successively functionalized with 3-aminopropyltrimethoxysilane and PA, and the exposed azido groups on the inner wall of the nanopore caused a negative rectification ratio (R) and varied upon reaction with the intracellular H2S. In the presence of H2S, azido groups could be reduced to amino groups, leading to a shift in the rectification ratio. The developed H2S nanopore sensing platform showed high resolution and excellent selectivity, making it reliable for the quantification of H2S in individual cells. The H2S concentrations in individual HeLa cells, MCF-7 cells, and HL7702 cells were effectively quantified using the approach.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Food Science & Technology
·
2026
·
IF 3
Jiayi Chen,Dandan Zhang,Lu Liu,Xiaoli Wu,Meihan Guo,Hong Yan Zou,Xi Yang
Herein, a cost-effective, naked-eye-readable platform for on-site biogenic amines (BAs) detection and shrimp freshness monitoring was developed based on a ratiometric fluorescent CDs–RhB hybrid nanosystem that was constructed by integrating carbon dots (CDs) with rhodamine B (RhB). Biogenic amines induced a significant enhancement in the green fluorescence emission of CDs, while the red fluorescence emission of RhB remained unchanged, enabling an instant self-calibration during detection. Loaded on filter paper to form disposable test strips, the nanosystem enabled a visible color transition from orange to green with increasing BAs concentration. Readable via a smartphone RGB app, the paper-based assay showed a linear response of 5.0–250 μM with a limit of detection (LOD) of 3.56 μM using histamine as the model analyte. Validated through on-site shrimp quality evaluation, the paper-based sensor established a reliable “nanoprobe–paper–phone” strategy, facilitating on-site and quantitative freshness assessment in real-world demand scenarios.
✓ 已验证
产品关联
DOI
高影响因子
Research
·
2026
·
IF 12.9
Changming Lan,Jing Liang,Jie Xu,Xinxin Wang,Xiao Liu,Yiran Ni,Yingnan Zhou,Ming-Bang Wu,Chao Zhang,Junqiu Liu,Baiheng Wu
Leveraging living materials such as algae as sustainable photocatalytic platform is highly promising for mitigating antibiotic water pollution; however, they are confronted with low catalytic efficiency and difficulty in recovery, as imposed by their passive, static working mode. Herein, we report a Janus microgel robot (JMR) that features the integration of magnetic-controlled mobility and living photocatalytic function, allowing for substantially boosting antibiotic degradation efficiency and efficient recovery in an actively magnetic-controlled manner. The key to the JMR lies in harnessing gas shear microfluidic technique to manipulate the spatial distribution of TiO2–Chlorella pyrenoidosa and Fe3O4 phases into a Janus architecture, followed by gel encapsulation to prevent cell leakage. Under simulated sunlight, the JMR system achieves 77% antibiotic degradation within 10 h, which is 10 times that of the free C. pyrenoidosa (7.6%). Moreover, we demonstrate that the JMR can be imparted with enhanced degradation efficiency by 10.6% and over 95% effectiveness through 3 consecutive operational cycles in actively magnetic-controlled mode. This work establishes a prototype for sustainable environmental biorobots and provides a novel strategy for photocatalytic-biological hybrid system design, advancing the next-generation living materials for water treatment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
·
2026
·
IF 5.9
Hui Li,Dadi Liu,Qianrou Fan,Yulu Li,Cheng Lv,Xinlu Wang,Yang He,Jinbing Cheng,Yebin Guan,Yumin Leng
Gold nanoclusters (AuNCs) have attracted significant interest due to their unique fluorescence properties in the environmental monitoring field. In this work, we report the first pH-dependent preparation of glutathione-protected AuNCs (Glu-AuNCs) with different fluorescent emission. The Glu-AuNCs shows the intense yellow emission from samples pH 1.0–5.5, and red emission from samples pH 11.0 to 12.5, respectively. The size of AuNCs depends on the pH of the reaction solution. The characterizations of UV–vis and photoluminescent (PL) spectra show the size of AuNCs increases with increasing samples pH value. The strongly red-emitting Glu-AuNCs were applied to detect Hg 2+ ions by fluorescence quenching. Owing to the specific Hg 2+ -Glu interactions, the fluorescent AuNCs protected by the interference biothiol, Glu, showed superior selective detection of Hg 2+ . The red-emitting Glu-AuNCs provided high sensitivity for Hg 2+ detection with widely linear range of 0–20 μM and a detection limit of 1.6 nM (0.32 ppb), which is compared with the reported data in literature. To show a potentially practical application, the developed assay method was applied to detect Hg 2+ in real samples and a certified reference material. The developed simple method for Hg 2+ detection with high selectivity and sensitivity opens a new idea for other sensor development.
✓ 已验证
产品关联
DOI
高影响因子
PLoS One
·
2026
·Vol. 21
·期 2
·e0340257
·
IF 2.8
Xiumei Wang,Qingyu Song,Lulu Li,Wenting Lin,Xiaoxu Zhao,Jie Pang
The preparation, structural characterization and properties analysis of novel konjac glucomannan (KGM)/soy protein isolate (SPI)/fatty acid (KS-FA) films were carried out in this paper. KS-FA films exhibited higher crystallinities than KS film. Moreover, incorporating fatty acids significantly affected the surface roughness and morphologies of KS film. KS-FA films had significantly (p < 0.05) higher water contact angle values than KS film. The rheological properties of the film-forming solution, thermal stabilities, mechanical, water vapor barrier and water resistance properties of KS film were also improved after incorporating appropriate concentrations of fatty acids. There were a 21.3-percent increase of glass transition temperature value, a 17-percent increase of water contact angle value, a 14.5-percent decrease of water solubility value, a 43-percent decrease of water vapor permeability value, a 1.08-fold increase of tensile strength value, and a 1.52-fold increase of elongation at break value in KS film with 0.7% lauric acid when compared with those of KS film. Furthermore, molecular docking and fourier transform infrared spectroscopy analyses suggested that KS-FA films were formed through hydrogen bonds and hydrophobic interactions. These findings highlight fatty acid-modified KGM/SPI films as promising biodegradable food packaging materials.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2026
·
IF 5.9
Shengnan Huang,Weiwei Zhi,Mengjie Zhao,Gaojian Wei,Manyu Zhang,Yu Chen,Yijing Li,Lihua Cao,Jingyi Qiao,Yurong Hu,Hui Zhao,Mingsan Miao,Xiali Zhu
To exploit the therapeutic synergy of nanoparticle-induced calcium overload and oxidative stress dysregulation, we developed a core-shell nanoplatform, termed CK@PTM (comprising kaempferol-loaded calcium peroxide nanoparticles coated with a PEG-tannic acid/manganese metal-phenolic network), to amplified therapeutic efficacy against breast cancer. Structurally, kaempferol (KAE)-loaded calcium peroxide (CaO₂) nanoparticles served as the functional core, subsequently enveloped by a dual-responsive metal-phenolic network (MPN) formed through Mn²⁺coordination with polyethylene glycol-modified tannic acid (PEG-TA). This hierarchical architecture enabled pH/glutathione (GSH) dual-responsive payload co-release, facilitated by acid-triggered CaO₂ dissolution concurrent with pH/GSH- triggered MPN decomposition. Critically, CK@PTM orchestrated a severe redox imbalance via concomitant GSH depletion and reactive oxygen species (ROS) burst, thereby amplifying tumoricidal activity. Cellular uptake assays revealed efficient CK@PTM internalization into breast cancer cells, potentially attributable to TA-enhanced membrane affinity. Both in vitro and in vivo evaluations demonstrated significant tumor growth suppression of CK@PTM, driven primarily by the synergistic reciprocal potentiation of KAE-augmented Ca²⁺ overload and nanoplatform-induced oxidative stress. Furthermore, CK@PTM triggered immunogenic cell death (ICD), as evidenced by damage-associated molecular pattern (DAMP) release, suggesting potential for activating T-cell-mediated antitumor immunity. Collectively, this nanotherapeutic strategy established a proof-of-concept paradigm for bidirectional amplification of calcium-overload and oxidative-stress signaling cascades, presenting a promising approach for solid tumors.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Cell Host & Microbe
·
2026
·
IF 23.2
Weijie Wen,Runping Su,Yunyun Liu,Zhiyang Feng,Yancai Li,Jieli Li,Ziyu Huang,Fen Zhang,Shanshan Gao,Yingfei Ma,Qinghua Zhou,Emad M. El-Omar,Jeremy J. Barr,Tao Zuo
The human gut harbors a diverse virome, believed to play a crucial role in maintaining intestinal homeostasis. However, the magnitude of heterogeneity of the gut mucosal virome, and how it differentially regulates host inflammation phenotypes, such as those observed in Crohn’s disease (CD), remains unclear. Here, we identify two mucosal DNA virome enterotypes (E1 and E2) in humans, with E2 subjects exhibiting higher virome diversity and nuanced bacteriophage-bacteria correlations. Moreover, E2-enterotyped CD patients exhibited higher Wulfhauvirus abundance than healthy controls. The E2 virome is causally more proinflammatory in inducing intestinal inflammation in mice. Mechanistically, the novel E2-virome-enriched phage øBTZT001P (belonging to Wulfhauvirus ) lysogenically infects Bacteroides thetaiotaomicron , increasing sphingosine production. Downstream, sphingosine suppresses the commensal bacterium Blautia obeum in the gut, leading to worsened intestinal inflammation. Our findings reveal that configurational differences in the gut virome may dictate disease outcome through a phage-bacteria-metabolite-intestine axis, highlighting the importance of gut phage-bacteria crosstalk in health.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL LETTERS
·
2026
·
IF 1.8
Quanxiu Wang,Zijin Chen,Jiaoyan Gao,Xingshuo Wang,Xinlei Huang,Yuting Shen,Hui Lu,Leilei Guo
Glutathione (GSH) is a critical bioactive molecule that plays an essential part in regulating the body’s redox homeostasis, and its concentration is of significant importance for the diagnosis of clinical conditions. In recent years, colorimetric techniques utilizing nanoenzymes have emerged as a novel approach for GSH determination. The development of nanoenzymes featuring straightforward synthesis, high catalytic efficiency, and cost-effectiveness is essential for achieving rapid and sensitive GSH determination. In this study, palladium nanocrystals (PdNCs) exhibiting peroxidase-like activity were successfully synthesized via a facile microwave-assisted method. Based on the specific thiol-PdNCs interaction and the associated color change of the catalytic system, a fast, straightforward, and highly sensitive colorimetric method was developed for the determination of GSH. Small-sized PdNCs with exposed (100) crystal planes exhibited exceptional peroxidase-like activity and efficiently catalyzed the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by H2O2 to produce a blue product. By exploiting the inhibitory effect of GSH on this catalytic system, sensitive GSH determination was achieved with linear ranges of 3–40 μM and 55–110 μM, as well as a low limit of detection (LOD) of 0.14 μM, outperforming previously reported methods. The method was further validated using serum samples, showing recovery rates of 96.36%–103.65% and relative standard deviations (RSDs) of 1.99%–3.38%. This PdNCs-based colorimetric strategy demonstrates promising potential for real-time GSH determination in clinical diagnostics.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry A
·
2026
·
IF 9.2
Yang Yao,Wanlin Wu,Rui Xiong
The construction industry faces an urgent need to develop sustainable alternatives to conventional energy-intensive materials such as concrete and ceramics. However, many existing alternatives are often constrained by insufficient mechanical strength, lack of recyclability, poor thermal insulation, or limited fire resistance. Drawing inspiration from historical building techniques that utilized plant fiber-mineral binder systems, this study overcomes their inherent limitations through advanced material design. We report a high-performance, low-carbon building bio-mineral composite fabricated under mild conditions by integrating a thermally induced hardening amorphous calcium carbonate mineral binder with waste wood sawdust. The synergistic interaction between these components endows the composite with outstanding mechanical properties, including a specific compressive strength of 36.87 MPa (g−1 cm−3) and a specific compressive modulus of 10.73 GPa (g−1 cm−3), substantially exceeding those of most conventional construction materials. Furthermore, the mineralized porous structure contributes to a UL-94 V-0 flame-retardant rating and a low thermal conductivity of 0.06 W (m−1 K−1). By bridging ancestral natural wisdom with modern materials science, this work not only delivers a high-performance material but also establishes a sustainable architectural pathway that “learns from yet surpasses antiquity,” offering a practical and scalable solution for greening the construction industry.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）