INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2024
·
IF 3.8
Ran Ran,Hanwen Yan,Guoliang Zhang,Zengxi Li,Gang Wang,Gongying Wang,Weiguang Su,Chunshan Li
Supported Cs-based catalysts are considered as potential candidates for methyl methacrylate (MMA) synthesis via one-step aldol condensation, but they suffer from low activity. In this paper, the acid–base properties of the Cs/SiO2 catalyst were modulated by loading different amounts of the Al element. The changes in structural and physicochemical properties following Al introduction were revealed by a series of characterizations. In-depth investigation of the catalytic mechanism through in situ DRIFT combined with DFT calculations unveiled the synergistic effects between the Al and Cs components on the promotion of catalytic performance. The results showed that the presence of Al species facilitated the formation of weak and medium acid and base sites, along with the dispersion of the active Cs component, leading to an improvement of MMA yield. Additionally, the kinetic studies indicated that the addition of Al efficiently reduced the activation energy in comparison to pristine Cs/SiO2.
研究领域:
化学工程
·
催化科学
✓ 已验证
DOI
高影响因子
Chemistry-An Asian Journal
·
2018
·Vol. 13
·期 9
·1206-1212
·
IF 3.692
Xiaojun Wang,Chang Gu,Hongzhi Zheng,Yu-Mo Zhang,Sean Xiao-An Zhang
A multi-state and multi-stimuli-responsive oxazine molecular switch that combines an electro-base property and sensitive base/acid-responsive properties was designed and synthesized. The multi-state structures of the molecular switch, with different colors, were predicted by comparing the optical properties with reference molecules and confirmed by using NMR spectroscopy. The color-switching mechanism under stimulation with acids and bases was investigated by using DFT calculations. Three single states can be obtained and the switching is unidirectional under acid and base stimulation. The electrochromic phenomenon of the molecular switch, which combines its electro-base and base-sensitive properties, was demonstrated. An electrochromic device that exhibited good electrochromic properties with excellent reversibility (2000 cycles) and high coloration efficiency (804 cm 2 C −1 ) was successfully constructed.
研究领域:
材料科学
·
化学
✓ 已验证
DOI
高影响因子
Inorganic and Nano-Metal Chemistry
·
2021
·
IF 1.716
Jiahua Guo,Yuqi Zhang,Shouwen Jin,Xiaoyun Ye,Kaikai Hu,Weiqiang Xu,Daqi Wang
Eight organic-inorganic hybrid salts [(HL1)(SbCl4)] (1) (L1 = N,N-dimethylbenzylamine), [(HL2)2(ZnCl4)] (2) (L2 = 4-chlorobenzylamine), [(HL2)(L2)(CuCl3)(H2O)2] (3), [(HL3)2(Sb2OCl6)] (4) (L3 = quinoline), [(HL4)4(Bi2Cl10)] (5) (L4 = 2-methylquinoline), [(HL5)(SbCl4)] (6) (L5 = 5,7-dimethyl-1,8-naphthyridine-2-amine), [(H2L6)(SbCl5)] (7) (L6 = 3,6-bis(imidazol-1-yl)pyridazine) and [(H2L7)2(CuBr4)2] · 7H2O (8) (L7 = di(2-benzimidazol-1-ylethyl)ether) were prepared and characterized by IR, XRD, EA and TG analysis. XRD analysis told that all of the complexes were 3 D net built from non-covalent bonds from the cations and the halometallates. The aryl rings of the cations in all of the compounds are essentially planar. The H2O also had crucial role in structure extension in 3 and 8. Extensive intermolecular interactions have been used in the self-assembly of diverse motifs, ranging from strong N-H···X (X = Br, Cl), N-H···O, N-H···N, O-H···O, O-H···Br H-bonds to weak CH2···O, CH3-Cl/CH2-Cl/CH-Cl, Cl-Cl, O-Br, CH3-π, CH2-π, Cl-π and π-π associations. The arrangements of the anions and cations in the solid are ruled not only by the size and symmetry of the cations, but also by the non-covalent bonds in the crystal structures.
研究领域:
无机化学
·
材料科学
✓ 已验证
DOI
高影响因子
POSTHARVEST BIOLOGY AND TECHNOLOGY
·
2020
·
IF 4.303
Taotao Li,Mingyang He,Jun Zeng,Zhongsuzhi Chen,Qu Hongxia,Xuewu Duan,Yueming Jiang
The effect of choline chloride (ChCl) on litchi pericarp browning and the potential regulating mechanism was investigated in this study. Results showed that 1 g L −1 ChCl significantly inhibited the development of pericarp browning and reduced respiration rate of litchi fruit. Meanwhile, choline chloride treatment delayed the programmed cell death (PCD) indicated by lower DNA laddering, inhibition of programmed cell death-related genes expression and higher soluble protein content. Additionally, ChCl treatment maintained higher ATP content and energy charge due to higher level of glycine betaine and regulation of energy metabolism related genes and ATPase activities by ChCl treatment. Finally, higher ATP status in ChCl treated fruit resulted in lower accumulation of reactive oxygen species via enhancing the activities of superoxide dismutase, catalase and ascorbate peroxidase. Taken together, the results obtained in this study suggested that choline chloride reduced pericarp browning of litchi fruit possibly through inhibiting energy deficiency mediated PCD .
研究领域:
植物生理学
·
食品科学
✓ 已验证
DOI
高影响因子
Journal of Energy Chemistry
·
2020
·
IF 7.216
Jin Xie,Ziren Zhou,Hongwei Qiao,Mengjiong Chen,Lijie Wang,Shuang Yang,Yu Hou,Huagui Yang
A controllable crystallization is of practical importance to produce high-quality perovskite thin films with reduced structural defects. Lewis bases as electron-pair donor chemicals can strongly coordinate to lead ions and have been extensively employed to manipulate the growth of perovskite crystals. In this work, we demonstrate a series of Lewis-base amides, for morphological regulation of methylammonium lead triiodide (MAPbI 3 ) thin films. The screened acetamide was demonstrated to decently improve the grain size, along with a spatial distribution at grain boundaries (GBs). The mesostructured solar cells of acetamide-modified absorbers yielded an optimized power conversion efficiency (PCE) of 20.04% with a mitigated open-circuit voltage ( V OC ) deficit of 0.39 V. This work provides a facile and cost-effective strategy toward controllable fabrication of high-performance MAPbI 3 solar cells.
研究领域:
材料科学
·
能源技术
✓ 已验证
DOI
高影响因子
Science China-Life Sciences
·
2024
·
IF 8
Zhang Zhen,Huang Weijun,Zhang Xiaoran,Wang Zhecun,Xie Manting,Xie Bingbing,Wang Yiling,Chen Xiaoyong,Xiang Andy Peng,Xiang Qiuling
Despite substantial advancements in modern medicine, the management of hypertension remains a major challenge. Stem cell-based therapies have recently demonstrated remarkable efficacy in treating cardiovascular diseases, including hypertension. However, the antihypertensive mechanism of mesenchymal stem cells (MSCs) has not been extensively explored. This study aimed to investigate the role of injected MSCs in regulating blood pressure homeostasis. Our previous study demonstrated that human induced pluripotent stem cell-derived mesenchymal stem cells (hiPSC-MSCs) are functional and homogeneous sources for MSC-based therapy. After the injection of hiPSC-MSCs, a significant reduction in blood pressure and end target organ inflammation were observed in spontaneously hypertensive rats (SHRs). Cell tracking assays demonstrated that the injected hiPSC-MSCs accumulated in the spleens of the SHRs. The injected hiPSC-MSCs accumulated adjacent to the splenic nerve, potentially contributing to the antihypertensive effects. Furthermore, the hiPSC-MSCs released abundant glutamate, which acts as a neuromodulator to activate the splenic sympathetic nerve. After inhibition of glutamate synthesis by siRNA, the ability of hiPSC-MSCs to activate sympathetic nerves was significantly diminished. In addition, the antihypertensive effects of hiPSC-MSCs were eliminated after splenic nerve denervation (SND), underscoring the critical role of the splenic nerve. Moreover, activation of the splenic nerve resulted in increased release of norepinephrine (NE), which increased the number of choline acetyltransferase-positive (ChAT + ) cells in the spleen and peripheral blood. Consequently, the acetylcholine (ACh) produced by elevated ChAT + cells could act as a vasodilator, lowering blood pressure and mitigating inflammation in end target organs. In summary, our findings indicate that hiPSC-MSCs effectively lower blood pressure in hypertension by influencing the splenic nerves and regulating ChAT + cells. The connection between blood pressure regulation and the splenic nerve may offer new insights into the treatment of hypertension.
研究领域:
干细胞治疗
·
心血管疾病
·
高血压
·
神经科学
·
药理学
✓ 已验证
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2014
·
IF 4.086
Qibo Zhang,Rui Wang,Konghao Chen,Yixin Hua
Electrochemical deoxygenation of porous CuO pellet to prepare copper was investigated in the 33.3-66.7 mol% Choline chloride (ChCl)-EG eutectic melt at 353 K. Cyclic voltammetry of the Pt-powder cavity microelectrode loaded with CuO powder exhibited that the solid CuO can be electrochemically reduced in solid state in the eutectic melt. Constant-voltage (2.0 to 2.4 V) electrolysis, with an assembled cathode of a sintered porous CuO pellet and a graphite anode, that performed in the eutectic melt demonstrated the conversion process of oxide-to metal as confirmed by scanning electron microscopy, energy-dispersive X-ray, and X-ray diffraction spectra. A mechanism for this reduction process has been proposed on the basis of the in situ formation of numerous gas at the cathode, emphasizing that the oxidation of cathodically generated O 2− ions occurred nearby along with the copper electroreduction , in which the new formed metal was served as a temporary anode, oxygen was generated at the interface of the reduced copper and electrolyte inside the cathode.
研究领域:
电化学
·
材料科学
·
冶金工程
·
无机化学
·
能源材料
✓ 已验证
DOI
高影响因子
TRANSITION METAL CHEMISTRY
·
2013
·Vol. 38
·期 4
·463-471
·
IF 1.184
Zhang Nan,Fan Yu-Hua,Bi Cai-Feng,Zhao Yu,Zhang Xia,Zhang Dong-Mei,Huang Gui-Mei
A pair of stereoisomers of nickel Schiff base complexes, namely [Ni(C 17 H 15 N 4 O 2 ) 2 ·2CH 3 OH] n ( 1 ) (C 17 H 15 N 4 O 2 = 2-acetylpyrazine- l -tryptophan) and [Ni(C 17 H 15 N 4 O 2 ) 2 ·2CH 3 OH] n ( 2 ) (C 17 H 15 N 4 O 2 = 2-acetylpyrazine- d -tryptophan), were synthesized and characterized by physico-chemical and spectroscopic methods. The X-ray diffraction single-crystal analyses indicate that the structure of 2 is essentially 0D monomeric, while a 2D layer structure is formed through N–H…O intermolecular hydrogen bonds for 1 . The interactions between complex 1 and calf thymus DNA were investigated by spectroscopic and viscometric methods. The results indicate that complex 1 interacts with DNA very strongly ( K
b = 1.01 × 10 7 mol −1 L and K
sq = 1.11). The nature of the binding seems to be mainly an electrostatic interaction between DNA and the complex. However, other binding modes, such as hydrogen bonding, may also be present in this system.
研究领域:
无机化学
·
配位化学
·
生物无机化学
·
分子药理学
·
核酸化学
✓ 已验证
DOI
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2020
·
IF 3.306
Shengling Li,Duanlin Cao,Xianjiao Meng,Zhiyong Hu,Zhichun Li,Changchun Yuan,Tao Zhou,Xinghua Han,Wenbing Ma
In this study, a novel schiff base fluorescent probe (E)- N' -(3-(benzo[d]thiazol-2-yl)-2-hydroxy-5-methylbenzylidene)-7-(diethylamino)-2-oxo-2 H -chromene-3-carbohydrazide ( CHS ) was synthesized for sequential detection of Al 3+ and pyrophosphate ions (PPi) in a DMSO/HEPES (4:1 v/v, pH = 7.4) buffer system and characterized by 1 H NMR, 13 C NMR, ESI-HR-MS and DFT calculation. Its detection limit was determined to be 0.16 μM for Al 3+ and 0.18 μM for PPi in a pH range of 4∼8, respectively. The Job’ s plot showed that the stoichiometric ratio to Al 3+ was 1:1, and CHS -Al 3+ showed highly selective recognition of PPi. The sensor CHS could also recognize Al 3+ and PPi and exhibited fluorescence enhancement and quenching properties in HeLa cells.
研究领域:
分析化学
·
生物分析
·
分子探针
·
细胞成像
·
金属离子检测
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLUTION CHEMISTRY
·
2015
·Vol. 44
·期 12
·2383-2392
·
IF 1.177
Zhou Li,Liu Chunli,Fan Liqun,Wang Jinhu,Wang Shumin
Enthalpies of solution and densities of diglycine in aqueous solutions of LiNO 3 , NaNO 3 and KNO 3 were measured at 298.15 K. Transfer enthalpies ( \( \Delta_{\text{tr}} H \) ) and transfer partial molar volumes ( \( \Delta_{\text{tr}} V_{\phi }^{0} \) ) were derived for diglycine. The transfer enthalpies of diglycine from water to the three alkali metal nitrates solutions are negative while the transfer partial molar volume values are positive. The absolute values of \( \Delta_{\text{tr}} H \) and \( \Delta_{\text{tr}} V_{\phi }^{0} \) from water to the same concentration in salt solutions in both cases vary in the relative order LiNO 3 < KNO 3 < NaNO 3 . The results are discussed in terms of electrostatic interaction and structural interactions. Electrostatic interaction between the diglycine zwitterion and salts gives large contributions to Δ tr
H and \( \Delta_{\text{tr}} V_{\phi }^{0} \) . But, structursal interaction is responsible for the abnormal behavior of diglycine in aqueous LiNO 3 solutions.
研究领域:
生物物理化学
·
溶液热力学
·
分子相互作用
·
药物溶解行为
·
生物相容性研究
✓ 已验证
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2017
·
IF 4.95
Dandan Song,Yan Li,Xiong Lu,Muxue Sun,Hui Liu,Guangming Yu,Faming Gao
A highly sensitive acetylcholinesterase (AChE) electrochemical biosensor for the quantitative determination of organophosphate pesticides (OPs) in vegetables and fruits based on palladium-copper nanowires (Pd-Cu NWs) was reported. AChE immobilized on the modified electrode could catalyze hydrolysis of acetylthiocholine chloride (ATCl), generating an irreversible oxidation peak. When exposed to the OPs, the activity of the AChE was inhibited and the current significantly decreased. The detection mechanism is based on the inhibition of AChE. The Pd-Cu NWs not only provide a large active surface area (0.268 ± 0.01) cm 2 for the immobilization of AChE, which was approximately 3.8 times higher than the bare glass carbon electrode, but also exhibit excellent electro-catalytic activity and remarkable electron mobility . The biosensor modified with Pd-Cu NWs displayed a good affinity to ATCl and catalyzed hydrolysis of ATCl, with a low Michaelis–Menten constant ( K M ) of 50.56 μM. Under optimized conditions, the AChE-Cs/Pd-Cu NWs/GCE biosensor detected malathion with wide linear ranges of 5–1000 ppt and 500–3000 ppb, and the low detection limit was 1.5 ppt (4.5 pM). In addition, the OPs biosensor has been applied to the analysis of malathion in commercial vegetable and fruit samples, with excellent recoveries in the range of 98.5%–113.5%. This work provides a simple, sensitive and effective platform for biosensors and exhibits future potential in practical application for the OPs assay.
研究领域:
分析化学
·
环境科学
·
生物技术
✓ 已验证
DOI
高影响因子
International Journal of Minerals Metallurgy and Materials
·
2024
·Vol. 31
·期 11
·2435-2444
·
IF 5.6
Tao Liming,Wang Jianjun,Liao Dejin,Jia Wenkai,Zhao Zihan,Che Wenfang,Qi Zhongxu,Sun Wei,Gao Zhiyong
Flotation is the most common method to obtain concentrate through the selective adsorption of collectors on target minerals to make them hydrophobic and floatable. In the hydrometallurgy of concentrate, collectors adsorbed on concentrate can damage ion-exchange resin and increase the chemical oxygen demand (COD) value of wastewater. In this work, we proposed a new scheme, i.e., desorbing the collectors from concentrate in ore dressing plant and reusing them in flotation flowsheet. Lead nitrate and benzohydroxamic acid (Pb-BHA) complex is a common collector in scheelite flotation. In this study, different physical (stirring or ultrasonic waves) and chemical (strong acid or alkali environment) methods for facilitating the desorption of Pb-BHA collector from scheelite concentrate were explored. Single-mineral desorption tests showed that under the condition of pulp pH 13 and ultrasonic treatment for 15 min, the highest desorption rates of Pb and BHA from the scheelite concentrate were 90.48% and 63.75%, respectively. Run-of-mine ore flotation tests revealed that the reuse of desorbed Pb and BHA reduced the collector dosage by 30% for BHA and 25% for Pb. The strong alkali environment broke the chemical bonds between Pb and BHA. The cavitation effect of ultrasonic waves effectively reduced the interaction intensity between Pb-BHA collector and scheelite surfaces. This method combining ultrasonic waves and strong alkali environment can effectively desorb the collectors from concentrate and provide “clean” scheelite concentrate for metallurgic plants; the reuse of desorbed collector in flotation flowsheet can reduce reagent cost for ore dressing plants.
研究领域:
矿物加工工程
·
环境科学与工程
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）