SusMat
·
2024
·Vol. 4
·期 3
·e220
·
IF 18.7
Xunliang Hu,Xiaoju Yang,Bingyi Song,Zhen Zhan,Ruixue Sun,Yantong Guo,Li-Ming Yang,Xuan Yang,Chun Zhang,Irshad Hussain,Xiaoyan Wang,Bien Tan
Highly crystalline organic semiconductors are ideal materials for photocatalytic hydrogen evolution in water splitting. However, the instability and complex synthesis processes of most reported organic molecule-based photocatalysts restrict their applications. In this study, we introduce benzo [1,2-b:4,5-bʹ] bis [1] benzothiophene-3,9-dicarboxylic acid, 5,5,11,11-tetraoxide (FSOCA), a highly crystalline, stable molecular crystal that is easy to synthesize and serves as an efficient photocatalyst for the hydrogen evolution reaction. FSOCA exhibits high efficiency in sacrificial hydrogen evolution reaction (760 µmol h −1 , 76 mmol g −1 h −1 at 330 mW cm −2 ; 570 µmol h −1 , 57 mmol g −1 h −1 at 250 mW cm −2 ), and FSOCA remains stable during photocatalysis for up to 400 h. Experiments and theoretical studies confirmed the presence of hydrogen bonds between the sulfone group and the sacrificial agent (ascorbic acid). This interaction significantly improved the oxidation reaction kinetics and boosted the photocatalytic performance. This study presents a scalable and convenient approach to synthesize highly crystalline, active, and stable organic photocatalysts with potential applications in large-scale photocatalysis.
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Hanwen Wang,Jiawei Wang,Hangyuan Zhang,Xinyang Wang,Xiaoping Rao
Emulsion-based delivery systems are extensively employed for encapsulating functional active ingredients, protecting them from degradation, and enhancing bioavailability and release efficiency. Here, a CO 2 -responsive surfactant synthesized from rosin displays rapid responsiveness to CO 2 at room temperature, transitioning reversibly switches between active and inactive states multiple times. The dual tertiary amines on the rosin rigid structure contributes to its CO 2 sensitivity. When in its active cationic form, in conjunction with silica nanoparticles , it exhibits desired Pickering emulsification performance across various oil phases. In the Pickering emulsion loaded with quercetin , the encapsulation efficiency and loading efficiency reached 80.50% and 0.69%, respectively, with stability lasting at least 30 days. The system provides robust protection for quercetin against external factors, such as UV and heat, revealing sustained release effects. This study investigated the potential of using rosin-based CO 2 -responsive surfactants alongside nanoparticles to design stable Pickering emulsion systems for active substance encapsulation and sustained release.
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ENERGY & FUELS
·
2024
·
IF 5.2
Yuchen Li,Dayu Liu,Xin Peng,Mengjiao Cao,Chenwei Zou,Bin Yuan,Yining Wu
Deep profile control is crucial for enhancing oil recovery due to the depletion of oil and gas resources in the near-well zone. However, using waterflooding to displace the oil in far-well zones with low permeability faces challenges related to limited swept volume and low recovery efficiency. In response, we synthesized PEO-b-PS amphiphilic self-assembled polymer nanoparticles using the reversible addition–fragmentation chain transfer polymerization (RAFT) method. The PEO-b-PS polymers with PS as the core-forming block and PEO as the outer stabilizer self-assemble into uniform spherical particles in water with a size of 100 nm, as demonstrated through DLS/AFM/TEM experiments. These PEO-b-PS nanoparticles do double duty as plugging agents in water breakthrough channels and oil displacement agents once encountering oil. The NMR online displacement experiment shows that the PEO-b-PS nanoparticles can migrate into in-depth formations and plug preferential water pathways. In addition, following the plugging of preferential water pathways, the PEO-b-PS amphiphilic self-assembled polymer emulsifies crude oil and enhances the oil displacement efficiency. Overall, this PEO-b-PS amphiphilic self-assembled polymer offers a pragmatic solution for enhanced oil recovery.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-11
·
IF 15.7
Hou Changshun,Guo Junjia,Sun Bonan,Chan Kai Fung,Song Xin,Zhang Li
Natural biological tissues exhibit different mechanical and surface properties. These disparate features make their connections with engineering materials quite difficult due to the lack of universal methods for tuning the interfacial bonding over a wide range. However, the precise control of interfacial properties, including modulus and adhesion on diverse biological tissues, requires overcoming multiple inherent and external barriers. Here we propose an interface-enhanced strategy by spatial and temporal anchoring of magnetic nanostickers for controlled bioadhesive properties. Fully exploiting the interactions from nanostickers by remote control enables the attached patch to achieve extremely high adhesion energy ( ~ 1250 J m -2 ) and interfacial fatigue resistance with a threshold of ~50 J m -2 , at a very low area density of nanostickers (4 μg/mm 2 ). The controlled interfacial properties as well as space and time for anchoring, lead to comprehensively tunable bioadhesion on diverse tissues such as skin, intestine, liver, and kidney, which are strongly desired in biomedical applications. Integration with fragile tissues in female Sprague-Dawley rats for 10 days further demonstrates that the anchored biointerface can adapt to the in vivo environment and promote postoperative recovery. The biointerface bridged by intelligent nanostickers prompts the methodology for bioadhesion towards controllable orientation.
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JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2025
·
IF 4.9
Wenlan Wu,Mengyi Zhang,Yang Lin,Xuening Li,Ying Liang,Ju Liang
Despite the development of numerous prodrugs for tumor therapy, their clinical application remains limited due to issues such as non-targeted delivery, uncontrolled release, and excessively rapid drug release rates. In this study, we synthesized a dual-functional prodrug, glycyrrhizic acid-polyethylene glycol-disulfide curcumin (GA-PEG-SS-CUR), by conjugating glycyrrhizic acid (GA), which possesses liver-targeting capabilities, with the anticancer agent curcumin (CUR). GA-PEG-SS-CUR can self-assemble in aqueous solutions to form micelles with an approximate diameter of ∼140 nm. In vitro drug release studies demonstrated that GA-PEG-SS-CUR exhibits a sensitive glutathione (GSH) response and sustained release characteristics; after 72 hours, the drug release rate was 30.5% at low GSH concentrations and 46.7% at high GSH concentrations. Due to GA receptor-mediated targeting, the uptake of GA-PEG-SS-CUR in HepG2 cells was significantly higher than that in L02 cells, and the internalization of GA-PEG-SS-CUR in HepG2 cells was markedly greater compared to unmodified PEG-SS-CUR. Cytotoxicity assays indicated that GA-PEG-SS-CUR enhanced the cytotoxicity against tumor cells compared to free CUR, while exhibiting lower toxicity towards normal L02 cells. Pharmacokinetic studies revealed that the half-life of CUR in GA-PEG-SS-CUR was 8.3 times longer than that of free CUR, extending the in vivo circulation time, with CUR accumulation at the tumor site being 6 times greater than that of free CUR, indicating significant tumor-homing ability. Therefore, the developed GA-PEG-SS-CUR represents an ideal delivery system for curcumin in tumor therapy.
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Advanced Science
·
2025
·
IF 14.1
Xiangyu Tang,Linlin Zhao,Yunfeng Guo,Ying Wang,Zhenke Wei,Xinyan Fan,Zefang Xiao,Haigang Wang,Yanjun Xie,Yonggui Wang
The growing environmental crisis caused by petroleum-based polymers has intensified the development of sustainable alternatives, with many biomass-derived polymers demonstrating potential for degradability, renewability, and low carbon footprints, though these properties can vary depending on structure and processing. However, traditional bio-based systems often lack tunability in mechanical properties, making it challenging to achieve both high strength and ductility. Herein, we report a high-performance, recyclable bio-based film (CAF-L) constructed via Diels-Alder dynamic covalent chemistry between furfuryl-functionalized cellulose acetate and maleimide-modified lignin. Thermally responsive dynamic Diels-Alder bonds, activated through heat-treatment, enable programmable network crosslinking that allows a smooth transition between strength- and ductility-dominated regimes, while maintaining high mechanical performance (tensile strength up to 52.3 MPa and elongation at break up to 545%). Structural characterization and molecular simulations reveal that Diels-Alder bond dynamics drive thermally induced structural reorganization of the polymer network, imparting rare adaptivity to biomass-based systems. In addition, CAF-L films exhibit outstanding UV shielding, oxygen barrier properties, and dual-mode recyclability through solvent dissolution and hot pressing. This work provides a scalable platform for constructing mechanically tunable, structurally reconfigurable, and environmentally resilient cellulosic bioplastic for sustainable packaging and circular material systems.
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COMPOSITES PART B-ENGINEERING
·
2024
·
IF 12.7
Tianchen Zhang,Yijiao Xue,Fei Song,Zheng Pan,Meng Zhang,Yonghong Zhou
As we all know, in the field of safety protection, it is crucial to develop protective materials with fire-retardant and vibration-damping properties. However, it is a challenging task to integrate different properties into a single polymer. To meet this challenge, we successfully developed a functionalized nano flame retardant (UiO-66-NH 2 @DOPO) by modifying UiO-66-NH 2 with 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO). This flame retardant was then incorporated into a porous polyurethane foam (MPUF) synthesized from a bio-based polyol, resulting in a bio-based MPUF composite with excellent vibration-damping, fire-retardant, smoke-suppressing, and anti-dripping properties. Due to the intumescent fire-retardant system formed by UiO-66-NH 2 and DOPO, when the additional amount of UiO-66-NH 2 @DOPO reached 25 %, the LOI value of the MPUF composite material was increased to 31.2 %, and the total smoke production (TSP) was reduced by 80.64 %. In addition, it obtained a V-0 rating in the UL94 test and exhibited excellent anti-dripping properties. In addition, owing to the reinforcement effect and stress dissipation of UiO-66-NH 2 @DOPO, the MPUF composites exhibited excellent energy dissipation and vibration-damping properties (maximum loss factor of 1.32 at 1.0 Hz). This new bio-based MPUF composite material has broad application prospects. It can become an innovative self-supporting vibration-damping and protective material in sports, transportation, and aerospace.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Feixiang Zhou,Linfeng Fu,Qingping Wu,Chao Ding,Le Yu,Weidong Zhou,Fahai Cao,Hui Liu,Jun Xu
Composite solid polymer electrolytes (SPEs) with metal organic frameworks (MOFs) fillers offer a promising route to improve lithium (Li)-ion transport and mechanical stability, but challenges such as poor filler/polymer compatibility and uncontrolled anion mobility. Herein, we present a molecularly engineered approach by covalently grafting a single-ion conductor (LiSTFSI) onto UIO-66-OH via an organosilane coupling agent (KH570), yielding a functional filler denoted as Li@UIO. When integrated into a PEO/LiTFSI matrix, Li@UIO constructs tripartite Li + conduction pathways through polymer segmental motion, intrinsic MOF ion-conducting sites, and MOF/polymer interfacial transport routes, while simultaneously immobilizing TFSI − anions and weakening Li + solvation structure. This synergistic design significantly enhances ion transport dynamics, achieving high ionic conductivity (2.57 × 10 −4 S/cm at 30 °C), enabling stable Li plating/stripping for over 3000 h with a low overpotential of 19 mV. In LiFePO 4 ‖Li@UIO/PL‖Li full cells, it delivers 85.1 % capacity retention after 600 cycles at 1C (60 °C). This study provides a new paradigm for designing multi-channel, single-ion-enhanced SPEs, offering a viable route toward safe, dendrite-free, high-energy-density lithium metal batteries.
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DYES AND PIGMENTS
·
2025
·
IF 4.2
Ke Sun,Zhongquan Zhu,Guowei Li,Yizhi Shao,Heng Xia,Hui Deng,Jianjun Zhang,Jiangang Gao,Gaopeng Shi,Yangyang Xu
Due to its widespread usage but high toxicity, the detection of cyanide has drawn special attention. However, in many works usually only one colorimetric or fluorescent detector was put forward for chemical sensing. Here in this contribution, two kinds of polydiacetylene (PDA) derivatives substituted by either o -hydroxybenzaldehyde or dicyanovinyl group were designed and explored for the optical sensing of cyanide. Firstly, these two PDA derivatives were polymerized in the form of vesicle individually and showed chromatic transition from blue to purple or red after the addition of cyanide into the aqueous solution. Then polyvinylidene fluoride membrane was chosen to incorporate the PDAs to form strip-based solid sensors, which could exhibit obvious blue-to-red colorimetric response upon exposure to cyanide aqueous solution with different concentrations in an orthogonal way. Interestingly, these two PDA derivatives remained blue phase in the presence of many common anions, thus demonstrating excellent selectivity for the distinguishment of cyanide. Besides the experimental characterization methods, such as UV–visible absorption and Raman spectroscopy, to study the underlying chemical mechanism, the principal component analysis method was also applied for the multivariate statistical analysis in combination with RGB (Red, Green, Blue) values to obtain a deep insight into the chromatic sensing of PDAs.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2025
·
IF 2.8
Jianhang Qiu,Xinrui Chai,Heguo Han,Linjian Sang,Yuxuan Sun,Yaohan Chen,Shenghai Li,Suobo Zhang
Polyurea emerges as a promising material for acid nanofiltration membranes due to its high hydrogen-bonding capacity and low electron density from carbonyl groups. However, conventional polyurea-based composite membranes suffer from limited separation performance and acid stability due to insufficient hydrophilicity and conjugated structures. In this study, a novel monomer, 3,5-diisocyanate benzoyl chloride, was synthesized and employed as the organic-phase precursor in interfacial polymerization to fabricate thin-film composite (TFC) membranes with polyurea-amide active layers. During polymerization, the acyl chloride groups undergo partial hydrolysis, introducing carboxylate anions into the active layer. The NF membrane shows over 98.6% rejection of MgSO 4 at pH 7, and membrane water permeability can reach 3.41 L m −2 h −1 bar −1 . Additionally, the aqueous phase monomer 2,4-diaminobenzenesulfonic acid was incorporated to construct a fully aromatic active layer, which strengthens intermolecular conjugation and acid resistance. Comparative analysis demonstrated that the synthesized membranes outperform traditional polyurea-based membranes (prepared via toluene diisocyanate and fatty amines) in acid stability: after soaking in 20 wt% H 2 SO 4 for 100 days, the MgSO 4 rejection remained nearly unchanged. This study establishes a molecular design strategy integrating hydrophilic functionalization and conjugated aromatic structures to address critical limitations in polyurea membranes, offering a pathway toward robust nanofiltration systems for acid-resistant applications.
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JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Hongmiao Wu,Xiao Shen,Mingjie Wei,Feng Zhang,Ze-Xian Low,Weihong Xing
Oil-water separation is a vital process across various industries, where membrane separation stands out as a promising, energy-efficient solution. Despite its potential, the widespread application is hindered by the limited durability of existing membrane surface engineering effects. This study introduces an innovative fabrication strategy to create a superhydrophobic and durable nanofibrous membrane for efficient oil-water separation. Utilizing electrospinning and a two-step sequential covalent-bonding dip-coating process, the membrane was chemically decorated with vinyl trichlorosilane, followed by a thiol-ene “Click” reaction with 1H, 1H, 2H, 2H-perfluorodecanethiol, resulting in a stable superhydrophobic and oleophilic surface. The membrane exhibited high permeation fluxes for various organic solvents, achieving separation efficiencies exceeding 99.5 % for non-emulsified mixtures (oil:water = 1:1) and over 99.7 % for hydrocarbon oil/water emulsions (oil:water = 99:1). Furthermore, the membrane demonstrated remarkable stability, enduring multiple filtration cycles and harsh chemical environments, including extended exposure to NaOH solutions. To validate its industrial applicability, the nanofibrous membrane was employed in a membrane extraction process post amide synthesis, successfully separating dichloromethane and water, thereby streamlining the extraction process. This work showcases a robust membrane surface engineering strategy for efficient oil-water separation.
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Pharmaceutics
·
2025
·Vol. 17
·期 10
·1263
·
IF 5.5
Jin Xue,Zifan Qiao,Shiyu Huang,Mubarak G. Bello,Lihua Chen
Background/Objectives:Ulcerative colitis (UC) involves chronic colon inflammation and oxidative stress. Treating UC is challenging due to systemic drug side effects and poor targeted delivery. Nanocarriers responsive to the UC microenvironment, particularly elevated reactive oxygen species (ROS), could overcome these limitations. This study developed an oral delivery system for ROS-triggered drug release and active targeting. Using ferulic acid (FER), a system was designed to enhance site-specific accumulation and therapeutic efficacy against colitis.Methods:A ROS-sensitive covalent organic framework (COF) was synthesized from γ-cyclodextrin and functionalized with folic acid (FA) to create a carrier (COF-FA) designed for potential active targeting. This carrier was loaded with FER to form FER@COF-FA. The system was characterized (SEM, FTIR, TGA), and its ROS scavenging and sustained drug release profiles were confirmed in vitro. Biocompatibility was evaluated in cell lines, and therapeutic efficacy was tested in a DSS-induced murine colitis model.Results:The synthesized FER@COF-FA demonstrated high drug loading, potent ROS-scavenging capability, and a sustained drug release profile. It showed excellent biocompatibility and, in the murine model, significantly outperformed free FER. Treatment alleviated disease severity, prevented colon shortening, restored healthy tissue histology, and rebalanced pro- and anti-inflammatory cytokines.Conclusions:The FER@COF-FA system represents a highly promising therapeutic strategy for UC. Its superior efficacy is attributed to a synergistic multi-mechanism approach, combining sustained release, ROS-responsive drug delivery, intrinsic antioxidant activity, and potential folate receptor-mediated targeting, which collectively enhance site-specific accumulation and therapeutic outcomes in the inflammatory colon microenvironment.
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