MICROCHIMICA ACTA
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2020
·Vol. 187
·期 12
·1-9
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IF 6.232
Peng Bo,Fan Mimi,Xu Jiamei,Guo Yang,Ma Yongjun,Zhou Min,Bai Jialei,Wang Jingfeng,Fang Yanjun
Blue carbon dots (BCDs) and red gold nanoclusters modified by bovine serum albumin (BSA-Au NCs) were selected as luminescent nanomaterials, and the nanohybrid materials were successfully prepared and applied to the fluorescent measurement of copper ions. The prepared ratio fluorescent probe has two emission peaks near 452 and 654 nm under an excitation of 330 nm. The fluorescence intensity was gradually quenched because Au NCs was aggregated in the presence of Cu 2+ , resulting in a gradation of the fluorescent color from red to pink to purple to blue for visual detection. BCDs have almost the same fluorescence intensity due to their light stability and chemical inertness to Cu 2+ and serve as a background reference in the sensing system. Under the optimal condition, the detection limit (LOD) is 16 nM, the linear range is 0.05–1.85 μM, and the coefficient of determination R 2 is 0.9987 for copper determination. Compared with other single probes, the ratio fluorescent probe in the current study has good water solubility, low cytotoxicity, and is easy to synthesize. The nanoprobe provides a high-quality and sensitive visible light platform for monitoring copper ions.
Graphical abstract
研究领域:
分析化学
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材料科学
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环境科学
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2017
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IF 5.401
Dongjian Zhu,Aishan Ren,Xingcun He,Yanghe Luo,Zhenhua Duan,Xiaowei Yan,Yuhao Xiong,Xing Zhong
A novel hemicyanine-based ratiometric fluorescent probe 3 for Cu 2+ was described. The probe exhibited fluorescence emission at 448 nm. Upon addition of Cu 2+ , the emission at 448 nm quenched and simultaneously generated a significant bathochromic shift of the emission maximum to 503 nm due to the Cu 2+ -triggered hydrolysis reaction of the picolinate moiety. Thus, a single-excitation, dual-emission ratiometric measurement with a large red shift in emission (Δ55 nm) and remarkable changes in the ratio (F 503nm /F 448nm ) of the emission intensity (R/R 0 up to 22-fold) could be established. Moreover, the probe exhibited a large Stokes shift, high sensitivity (detection limit of 1.1 nM), and high selectivity for Cu 2+ over other metal ions in complete aqueous solution.
研究领域:
分析化学
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生物化学
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DOI
高影响因子
Scientific Reports
·
2017
·Vol. 7
·期 1
·1-9
·
IF 4.259
Wang Yulong,Wang Limin,Su Zhenhe,Xue Juanjuan,Dong Jinbo,Zhang Cunzheng,Hua Xiude,Wang Minghua,Liu Fengquan
We use the multiple antibiotic resistance regulator (MarR), as a highly selective biorecognition elements in a multipath colourimetric sensing strategy for the fast detection of Cu 2+ in water samples. The colourimetric assay is based on the aggregation of MarR-coated gold nanoparticles in the presence of Cu 2+ ions, which induces a red-to-purple colour change of the solution. The colour variation in the gold nanoparticle aggregation process can be used for qualitative and quantitative detection of Cu 2+ by the naked eye, and with UV–vis and smartphone-based approaches. The three analysis techniques used in the multipath colourimetric assay complement each other and provide greater flexibility for differing requirements and conditions, making the assay highly applicable for Cu 2+ detection. Under optimal conditions, the Cu 2+ concentration was quantified in less than 5 min with limits of detection for the naked eye, UV–vis and smartphone-based approaches of 1 μM, 405 nM and 61 nM, respectively. Moreover, the sensing system exhibited excellent selectivity and practical application for Cu 2+ detection in real water samples. Thus, our strategy has great potential for application in on-site monitoring of Cu 2+ , and the unique response of MarR towards copper ions may provide a new approach to Cu 2+ sensing.
研究领域:
分析化学
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环境科学
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纳米技术
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DOI
PubMed
高影响因子
MOLECULES
·
2024
·Vol. 29
·期 10
·2167
·
IF 4.2
Yuxia Li,Min Li,Liuzhi Hu,Baozhu Zhang
In this study, Cu2+modulated silver nanoclusters were constructed for the turn-on, label-free detection of L-histidine. Six Ag NCs protected by oligonucleotides (DNA-Ag NCs) were tested in a series of experiments. Finally, A-DAN-Ag NCs were chosen as the best candidate due to their excellent fluorescent properties. The fluorescence of A-DAN-Ag NCs was quenched using Cu2+through energy or electron transfer. However, quenched fluorescence could be restored dramatically in the presence of L-histidine due to Cu2+liberation from A-DAN-Ag NCs and because of the chelation between the imidazole group of L-histidine and Cu2+. The proposed sensor exhibited high selectivity towards L-histidine over other amino acids, with a limit of detection (LOD) of 0.096 μM ranging from 0 to 8 μM. The proposed sensor succeeded in detecting L-histidine in diluted human urine. Therefore, the sensor has promising practical applications in biological systems.
研究领域:
生物化学
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分析化学
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生物医学
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产品关联
DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
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2024
·
IF 10.7
Xiuqin Fang,Chang Wang,Hong-Hui Shu,Sheng-Li Han,Cheng-Mei Liu
Bisphenol A (BPA), a prominent endocrine-disrupting compound, has garnered considerable attention due to its urgent need for rapid removal from water. Herein, we first used a novel reactive phosphine oxide containing tertiary amines as crosslinker to prepare water-insoluble crosslinked β-cyclodextrin (β-CD) adsorbent via radical-mediated thiol–ene polymerization. Owing to the synergistic hydrogen-bond (H-bond) interactions of functional groups (tertiary amine and P O groups) toward BPA, the resulted adsorbents showed fast adsorption kinetics to BPA with an adsorption equilibrium time of 5 min. After six adsorption–desorption cycles, the removal efficiency of BPA was 92.5 %, indicating its excellent reusability. Due to the presence of the C S bonds, the β-CD -derived bio-adsorbents offered binding sites for Cu 2+ ions, resulting in a maximum adsorption capacity of 113.89 mg g −1 .
研究领域:
环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2024
·
IF 8.1
Chengmin Hou,Ying Zhang,Qianqian Liao,Qianruo Chen
A novel adsorbent material, nylon@Fe 3 O 4 , was prepared by co-precipitation of nylon and FeSO 4 /FeCl 3 /NaOH solution. The structure of the composite was characterized using FTIR and TG methods. The results of FTIR and TG indicated that nylon@Fe 3 O 4 was successfully synthesized. The adsorption effect of nylon@Fe 3 O 4 on Cu(II) was explored under different experimental conditions. The optimum adsorption conditions of nylon@Fe 3 O 4 on Cu(II) were reached when the amount of composite was 12.50 mg, the concentration of Cu(II) was 15.36 mg/L, the reaction temperature was 50 °C, and the pH value was 9. Under the above conditions, the optimum adsorption efficiency was 94.67 % and the optimum adsorption capacity was 11.57 mg/g. The kinetic modeling indicated that the adsorption of nylon@Fe 3 O 4 belonged to chemisorption, and the initial adsorption rate (h = 69.92 mg/g/min) was larger, which indicated that the nylon@Fe 3 O 4 adsorption rate was faster. The adsorption isotherm experiments showed that the nylon@Fe 3 O 4 adsorption process occurred in the monomolecular layer adsorption, and the separation coefficients 0 < R L = 0.322/0.300/0.287 < 1, which indicated that the adsorption process of nylon@Fe 3 O 4 for Cu(II) was favorable adsorption. The adsorption thermodynamics showed that Δ G 0 < 0, Δ S 0 = 118 J/mol/K > 0, and Δ H 0 = 31.14 kJ/mol > 0, indicating that the adsorption process of nylon@Fe 3 O 4 on Cu(II) was spontaneous and favorable adsorption. Through 8 cycle experiments, the adsorption efficiency decreased from 94.67 % to 61.55 %, so nylon@Fe 3 O 4 had good regenerative performance. In conclusion, nylon@Fe 3 O 4 has potential applications in the adsorption of heavy metal ions.
研究领域:
材料科学
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环境科学
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产品关联
DOI
高影响因子
ANALYTICA CHIMICA ACTA
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2025
·
IF 6
Yingli Guo,Xingping Zhang,Hualin Yang,Yu Zhou
Background Ochratoxin A (OTA) is a widespread mycotoxin with nephrotoxic, neurotoxic and immunotoxic properties. It exhibits elevated thermal stability and a prolonged half-life and is resistant to removal. Long-term exposure to OTA increases the risk of carcinogenesis and influences human health. The detection methods of single signal mode had poor anti-interference ability and were prone to false positive results, while the detection method of multi-signal mode has higher adaptability to conditions and can offset environmental interference through self-correction. Therefore, proposing multi-signal and high-sensitivity strategies to detect OTA levels in various foods is all-important. Results A triple-readout immunoassay based on copper ions trigger was developed for detecting Ochratoxin A. The ascorbic acid 2-phosphate (AAP) was hydrolyzed to ascorbic acid (AA) by alkaline phosphatase (ALP). The unreacted AAP rapidly coordinated with Cu 2+ to produce green Cu 2+ -AAP complexes which emitted blue/green (B/G) signals. Meanwhile, Cu 2+ oxidized AA to produce dehydroascorbic acid (DHAA) which reacted with o-phenylenediamine (OPD) to form the blue-fluorescence quinoxaline derivative (DFQ). Simultaneously, Cu 2+ oxidized the unreacted OPD to form yellow 2,3-diaminophenazine (DAP) which produced yellow signals (Y). The B/G and Y was read by a smartphone. The limits of detection (LOD) of B/G, fluorescence and Y value readout models were 0.13 ng/mL, 0.16 ng/mL and 0.15 ng/mL. Their linear ranges were 6.25–100 ng/mL, 6.25–200 ng/mL and 3.13–12.5 ng/mL. Besides, all three readout models showed excellent specificity for OTA, and the recovery rates were satisfactory from 94.79 % to 112.68 %. Significance A triple-readout immunoassay based on copper ions trigger for the detection of ochratoxin A was constructed. The materials for detection are accessible and economical. Triple signal modes not only complement and verify each other to improve the reliability of the results but also can be selected according to the detection scenes to increase the freedom of detection. It can be used to detect other targets by altering the coated antigen and its corresponding antibody.
研究领域:
食品安全检测
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分析化学
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生物化学
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产品关联
DOI
PubMed
高影响因子
Journal of Physical Chemistry C
·
2025
·
IF 3.2
Xiaohui Li,Jie Wang,Guohao Li,Yingxinjie Wang,Zerui Chen,Ziying Zhang,Xiuqiang Xie,Nan Zhang
MXenes attract interest in diverse fields but suffer from fast structural degradation in aqueous solutions and even worse in the presence of transition metal ions. This hinders the storage of MXenes and the preparation of MXene-based composites. Here, we report an efficient way to stabilize Ti3C2Tx MXene in the presence of Cu2+ in aqueous solution by chelation chemistry using trisodium citrate dihydrate (SC). Furthermore, a BiCuS1.5/Ti3C2Tx composite was successfully prepared with SC, during which Ti3C2Tx is more stable than that without additives. The results show that the stabilization of Ti3C2Tx is beneficial in utilizing the synergistic advantages of Ti3C2Tx and metal compounds for zinc ion batteries. This work provides a simple paradigm for enhancing the antioxidation of MXene at room and high temperatures in water in the presence of transition metal ions, opening new prospects for MXene applications.
研究领域:
材料科学
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电化学
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纳米技术
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产品关联
DOI
高影响因子
Journal of Materials Chemistry B
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2025
·
IF 5.7
Ying Hu,Mingjun Li,Xun Xu,Nan Ma,Jiahao Luo,Xiaoxuan Wu,Qixiang Ping,Xiao Lin,Tingbin Zhang,Chunyong Liang,Lei Yang
Prosthetic joint infection (PJI) remains a significant challenge in clinical applications. It not only impedes the recovery of bone tissue at the site of bone defect but also leads to multiple debridements, long-lasting antibiotic treatment and even secondary replacement. Titanium alloy Ti6Al4V (TC4) is widely used in orthopedic implants due to its excellent mechanical properties and biocompatibility; however, it lacks inherent antibacterial and osteoinductive functions. In this study, a composite coating based on polyvinyl alcohol (PVA) with tissue repair and antibacterial properties was applied on the surface of TC4. A PVA gel coating functionalized with terpyridine and catechol groups (PVA–TP–CA) was synthesized and subsequently complexed with copper (Cu) ions. The differential binding affinities of TP and CA groups to Cu enabled a sustained and controlled release of metal ions. Furthermore, a micro–nano surface structure was fabricated on TC4 using femtosecond laser technology to achieve a micro–nano structure interface and enhanced bonding strength. Biological evaluations demonstrated that the modified surface significantly improved the antibacterial, angiogenic, and osteogenic properties of TC4. These findings indicate that this multifunctional composite coating holds great promise for surface modification of orthopedic implants, offering an effective strategy for preventing PJI while promoting bone regeneration.
研究领域:
生物医学工程
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材料科学
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组织工程
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产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2022
·
IF 8.008
Ye Ma,Ming Li,Kun Pang,Minggang Zhao
Trace analyte detection in a complex environment such as in seawater is usually challenging for classic redox-based electrochemical sensors since the matrix effect of high salinity and various interfering species with similar redox properties can generate false positive/negative signals, thus impacting the sensitivity and specificity of the sensors. In this work, unlike redox-based approaches, we propose a novel sensing mode that relies on dual-modulated interfacial energy barriers of heterojunctions. By constructing the hierarchical structure of Ni/TiO2/porous-reduced graphene oxide/chitosan (CS), we introduce interfacial energy barriers of Schottky junctions into the electrochemical sensors for Cu2+. Most importantly, we found that two factors, light and the electrostatic interactions between the heterojunctions and Cu2+, can be coupled to regulate the height of the interfacial energy barrier and at last exponentially magnify the sensing signals in response to Cu2+. Since the electrostatic interaction is inert to redox, the proposed sensor is robust against most interfering species even in seawater. Illumination further enhances its sensitivity by 6.23 times and endows it a limit of detection of 0.22 nM. Such a dual-modulated sensing mode is also valid in other heterojunctions such as in the p–n junctions of Ni/NiO/MoS2/CS, demonstrating its potential in more universal applications.
研究领域:
材料科学
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环境科学
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电化学传感
✓ 已验证
DOI
高影响因子
JOURNAL OF LUMINESCENCE
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2013
·
IF 2.144
Weiguang Kong,Huizhen Wu,Zhenyu Ye,Ruifeng Li,Tianning Xu,Bingpo Zhang
Carbon dots with unique characters of chemical inertness, low cytotoxicity and good biocompatibility, demonstrate important applications in biology and optoelectronics . In this paper we report the optical properties of pH-sensitive carbon dots with different surface modifications. The as-prepared carbon dots can be well dispersed in water by modifying with acid, alkali or metal ions though they tend to form a suspension when being directly dispersed in water. We find that the carbon dots dispersed in water show a new emission and absorption character which is tunable due to the pH-sensitive nature. It is firstly proved that the addition of bivalent copper ions offers a high color contrast for visual colorimetric assays for pH measurement. The effect of surface defects with different modification on the performances of the carbon dots is also explored with a core–shell model. The hydro-dispersed carbon dots can be potentially utilized for cellular imaging or metal ion probes in biochemistry.
研究领域:
生物技术
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材料科学
·
光学
✓ 已验证
DOI
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
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2025
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IF 3.7
Zhicheng Tang,Tianwei Wang,Hua Lin,Shoulong Hao,Shufen Zhang,Rongwen Lu
Amination of 1-amino-4-bromoanthraquinone-2-sulfonic acid (BAA), crucial for anthraquinone-type dyes production, relies on Cu+ catalysis. However, Cu+ disproportionation causes catalyst deactivation, requiring large amounts of Cu catalysts (e.g., CuSO4 or CuCl) and reductants (e.g., FeSO4), introducing heavy metals and increasing water consumption to remove byproducts and metals, raising both environmental and economic costs. To address these challenges, we introduce a groundbreaking strategy for the in-situ generation of Cu+ using symmetrical Cu electrodes under alternating current (AC) electrolysis. This method achieves 100% conversion of BAA in the amination with 3,5-diamino-2,4,6-trimethylbenzene sulfonic acid (M Acid) with 95% yield, while also providing a solution to the issue of Cu+ disproportionation without the need for any additional copper catalysts or reductants, demonstrating a broad substrate scope and significantly reducing water usage in post-treatment. Characterization techniques, including X-ray photoelectron spectroscopy, X-ray diffraction, and electrochemical impedance spectroscopy, reveal that the passive Cu2O film formed on the symmetrical Cu electrodes under AC electrolysis continuously generates Cu+, which is crucial for the reaction. This approach is scalable, environmentally friendly, and holds great potential for industrial applications, offering substantial economic benefits while reducing environmental impact.
研究领域:
化学工程
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）