SURFACE & COATINGS TECHNOLOGY
·
2024
·
IF 5.3
Dongjia Li,Bo Xiao,Xinyi Dai,Chao Wang,Yawei Wei,Haijun Chen,Yi Mai,Fuzhong Wu,Jiexi Wang
Amid the fast growth of lithium-ion batteries, LiNi 0.5 Mn 1.5 O 4 (LNMO) with a 4.7 V working voltage and cost advantages has gained significant attention. The instability of LNMO structure during high-voltage cycling leads to significant side reactions with the electrolyte, hindering its commercial development. Our study introduces a co-crystallization calcination strategy to enhance the optimization of LNMO. This study utilized a straightforward wet chemistry approach to combine the precursor of NASICON-type solid electrolyte Mg 0.5 Ti 2 (PO 4 ) 3 (MTP) with the precursor of LNMO. Subsequently, a MTP coating was formed in-situ on the surface of LNMO through a single-step calcination process. Co-crystallization and calcination processes limit LNMO particle secondary growth, shorten Li + diffusion path , achieve Mg 2+ and Ti 4+ co-doping, enhance structural stability , and result in triple modification, leading to a significant improvement in electrochemical performance . Among them, LNMO with a 1 % molar ratio modified by MTP reaches 81.7 % of the initial capacity after 500 cycles at room temperature and 84.3 % after 180 cycles at 55 °C. Under identical conditions, unmodified samples have 39.3 % and 76.3 %, respectively. Our research explores a novel application of NASICON-type solid electrolytes in modifying LNMO cathode material .
研究领域:
材料科学
·
能源存储与转换
✓ 已验证
DOI
高影响因子
PHARMAZIE
·
2018
·Vol. 73
·期 8
·465-468
·
IF 1.016
Ma Wenxue,Yao Yawen,Gu Yuyan,Li Fang,Cai Jiaxuan,He Baozhu,Chen Qiuyan,Fang Jian,Ouyang Zizhang
Acute phase protein pentraxin 3 (PTX3) is increased in patients with atherosclerotic cardiovascular diseases, such as acute coronary syndrome and coronary artery vulnerability, thereby serving as an important biomarker for the prognosis of cardiovascular diseases. This study was designed
to evaluate the effects of statins on the expression of PTX3 in human endothelial cells. We observed that PTX3 is a TNFα inducible protein in human endothelial cells. In contrast, treatment with simvastatin reduces basal as well as TNFα induced gene and protein expression of PTX3
in a dose- and time-dependent manner. Our study suggests that reducing PTX3 expression by statins could contribute to its protective effects against endothelial dysfunction and coronary artery plaque destabilization.
研究领域:
心血管疾病
·
药理学
·
分子生物学
✓ 已验证
DOI
高影响因子
THERMOCHIMICA ACTA
·
2016
·
IF 1.938
X.K. Gao,X. Wen,H. Zhou,Q. Zhu,J.L. Wang,X.Y. Li
In this work, a novel and simple method was put forward to measure the isobaric specific heat capacity for the kerosene RP-3 with a flow-calorimeter at the conditions of high temperature and high pressure. Based on the energy conservation principle, the formula for heat capacity was derived and its measurement was realized by the convective mixing method between the hot and cold fuel. Taking the precision of the instrument and the error transfer into account, the relative expanded uncertainty of this method was acquired of about ± 6.38% (coverage factor k = 2). Meanwhile, the accuracy and reliability were verified by the standard material of water and n -decane. In the temperature range from (296.2–719.0) K and under pressure range from (2.4–4.0) MPa, the measurement for the kerosene RP-3 was carried out and the experimental observations were compared and agreed well with the published data. At last, an empirical correlation relationship of heat capacity due to the temperature and pressure was presented by using Garg’s model with the measured experimental data.
研究领域:
物理化学
·
能源工程
✓ 已验证
DOI
高影响因子
Materials Express
·
2023
·Vol. 13
·期 8
·1339-1345
·
IF 0.7
Liao Wanrong,Fang Wang,Xu Juan
Lung cancer is a common malignancy of the respiratory system with a high morbidity and mortality. We intended to identify the apoptosis-promoting role of tripterine in lung cancer. Lung cancer SPC-A-1 cells were exposed to low, moderate, and high dosage of tripterine (2, 5 and 10 μmol/L)
with the model group not being intervened. After treatment, the role of tripterine in SPC-A-1 cell apoptosis was observed. In addition, lung cancer cells were transfected with TNF-α mimic (pc-TNF-α group) and TNF-α inhibitor (si-TNF-α group).
Tripterine +pc-TNF-α group was set up to determine the interaction between tripterine and TNF-α. The cell survival rate, TNF-α and Caspase-3 expression levels then were detected by MTT and flow cytometry. Tripteryglide treatment dose-dependently decreased
lung cancer cell viability and induced cell apoptosis, resulting in an increase of TNF-α expression. However, when TNF-α expression was inhibited upon transfection, SPC-A-1 cell apoptosis was suppressed. TNF-α mimics activated apoptosis and up-regulated
Caspase-3 expression. Combination of tripteryglide and TNF-α mimics more significantly elevated apoptotic rate of lung cancer cells when elevating the content of Caspase-3. SPC-A-1 cells are highly sensitive to TNF-α and TNF-α significantly increases
the activity and expression of Caspase-3. Tripteryglide can up-regulate TNF-α expression to facilitate lung cancer cell apoptosis and increase Caspase-3 expression.
研究领域:
肿瘤学
·
药理学
·
细胞生物学
✓ 已验证
DOI
高影响因子
GENOME BIOLOGY
·
2024
·Vol. 25
·期 1
·1-26
·
IF 10.1
Sun Daming,Bian Gaorui,Zhang Kai,Liu Ning,Yin Yuyang,Hou Yuanlong,Xie Fei,Zhu Weiyun,Mao Shengyong,Liu Junhua
Background The function of diverse ruminal microbes is tightly linked to rumen development and host physiology. The system of ruminal microbes is an excellent model to clarify the fundamental ecological relationships among complex nutrient–microbiome–host interactions. Here, neonatal lambs are introduced to different dietary regimes to investigate the influences of early-life crosstalk between nutrients and microbiome on rumen development. Results We find starchy corn-soybean starter-fed lambs exhibit the thickest ruminal epithelia and fiber-rich alfalfa hay-fed lambs have the thickest rumen muscle. Metabolome and metagenome data reveal that indole-3-carboxaldehyde (3-IAld) and prostaglandin D2 (PGD2) are the top characteristic ruminal metabolites associated with ruminal epithelial and muscular development, which depend on the enhanced ruminal microbial synthesis potential of 3-IAld and PGD2. Moreover, microbial culture experiment first demonstrates that Bifidobacterium pseudolongum is able to convert tryptophan into 3-IAld and Candida albicans is a key producer for PGD2. Transcriptome sequencing of the ruminal epithelia and smooth muscle shows that ruminal epithelial and muscular development is accompanied by Wnt and Ca 2+ signaling pathway activation. Primary cell cultures further confirm that 3-IAld promotes ruminal epithelial cell proliferation depending on AhR-wnt/β-catenin signaling pathway and PGD2 accelerates ruminal smooth muscle cell proliferation via Ca 2+ signaling pathway. Furthermore, we find that 3-IAld and PGD2 infusion promote ruminal epithelial and musculature development in lambs. Conclusions This study demonstrates that early-life ruminal microbiome-derived 3-IAld and PGD2 are effective promoters of rumen development, which enhances our understanding of nutrient–microbiome–host interactions in early life.
研究领域:
动物科学
·
微生物学
·
分子生物学
✓ 已验证
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
·
2020
·
IF 4.825
Ji Wu,Ke Cao,Cai-Yan Zhang,Tao-Tao Xu,Xin-Yu Wen,Bo Li,Junxiao Yang
A palladium catalyzed selective B(3)–H activation/oxidative dehydrogenative coupling for the synthesis of bis(o-carborane)s connected with B(3)–B(3′) and B(3)–B(6′) bonds has been developed for the first time. A plausible mechanism involving stepwise activation of B(3)–H and B(3′/6′)–H bonds by PdII and PdIV was proposed. This work is the first example and the most efficient protocol for synthesis of bis(o-carborane)s connected with B(3)–B(3′) and B(3)–B(6′) bonds, which has important reference for design, synthesis, and application of bis(o-carborane)s in related fields.
研究领域:
有机化学
·
材料科学
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2021
·
IF 3.498
Qiao Zhao,Hanbo Li,Yaan Cao
A series of the In(OH) 3 species modified ZnS (ZnS–In(OH) 3 X% (X = 2, 5, 7, 10)) photocatalysts were synthesized by a hydrothermal method . ZnS–In(OH) 3 X% (X = 2, 5, 7, 10) exhibited the improvement of photocatalytic activity for the photoreduction of CO 2 into CO compared with ZnS. Characterized by X-ray diffraction (XRD), fourier transforms infrared spectra (FT-IR), high resolution transmission electron microscope (HRTEM), X-ray photoelectron spectroscopy (XPS) valence band spectra, UV–vis diffuse reflectance spectra, photoluminescence (PL) and time-resolved PL decay curves, the crystal structure, band structure and behaviors of photogenerated charge carriers for photocatalyst were explored up. It was revealed that the modification of In(OH) 3 surface species on surface of ZnS can prolong the fluorescence lifetimes of photogenerated charge carriers, enhance the separate of photoinduced charge carriers efficiently and promote better matching between the band structure and the redox potential of the CO 2 /CO, resulting in improvement of photocatalytic activity efficiently for ZnS–In(OH) 3 X% (X = 2, 5, 7, 10) photocatalysts . This work may offer a new understanding to study the effect of surface species modification on photocatalytic performance of photocatalyst.
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
·
2018
·
IF 2.21
Zhenglong Yang,Jing Yu,Kangyu Fu,Fengfeng Tang
The poly(3-hexylthiophene) - multiwalled carbon nanotube hybrid material (P3HT-MWCNT) was successfully prepared in the Cu(I)/DBU catalyst system via in-situ click reaction. The properties of P3HT-MWCNT were measured by FTIR, 1 H NMR, UV-vis, XRD , TEM , SEM . The fluorescence spectrum of P3HT-MWCNT proved the covalent bond between P3HT and MWCNT, and P3HT could be coated on the surface of MWCNT. Compared with the physical blends of P3HT and MWCNT, P3HT-MWCNT prepared by click chemistry exhibited better thermal stability and a higher melting point of 243.2 °C. TG results also indicated that P3HT content of P3HT-MWCNT was 21.4%. It was expected to prepare novel organic-inorganic donor-acceptor hybrid material with good solubility, optical and thermal stability, which may be a promising material applied in preparation of organic photoelectron in the future.
研究领域:
材料科学
·
有机化学
✓ 已验证
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2021
·
IF 6.165
Dan Zhang,Junhui Pan,Deming Gong,Guowen Zhang
Indole-3-butyric acid (IBA) is a broad-spectrum efficient plant growth regulator. It has been widely used in crop production, but may have a potential security risk due to its residual accumulation in agricultural products. Herein, the binding mode between IBA and calf thymus DNA (ctDNA) and influence of IBA on the structure of ctDNA were explored by using spectroscopic methods, viscosity measurement, melting temperature studies coupled with computational approaches. Fluorescence titration results indicated that ctDNA induced IBA fluorescence quenching in a static manner. The measured thermodynamic parameters demonstrated that the structure of IBA-ctDNA complex was primarily stabilized by hydrogen bonds and van der Waals forces. Fluorescence experiments, viscosity analyses and circular dichroism (CD) measurements confirmed that IBA interacted with ctDNA in terms of groove mode with no significant conformational change of ctDNA. Furthermore, molecular docking showed that IBA was preferentially bound to the minor groove of ctDNA rich in A-T bases. Molecular dynamics simulation further revealed IBA and DNA forming a stable complex and IBA could slightly increase the flexibility of ctDNA base pairs. In addition, IBA did not cause significant damage to the structure of DNA. These findings may supply conducive insights into the toxicity mechanisms of IBA at the molecular level.
研究领域:
生物化学
·
分子生物学
·
毒理学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2021
·Vol. 11
·期 52
·32671-32679
·
IF 3.361
Hailian Bao,Xiaodi Chen,Rui Yuan,Chao Zhang,Shiai Xu
A surface heterojunction catalyst of g-C3N4–PEDOT/P3HT with P3HT and PEDOT as the polymer sensitizer and hole transport pathway is successfully prepared. The as constructed g-C3N4–PEDOT/P3HT composite exhibits a photocatalyst H2 evolution rate up to 427703.3 μmol h−1 g−1 which is 1059 times higher than that of g-C3N4, 118 times higher than that of g-C3N4–PEDOT with ascorbic acid as sacrificial reagents. What's more, the g-C3N4–PEDOT/P3HT can even show an obviously enhanced photocatalytic H2 evolution rate which is 6.1 times higher than that of pure g-C3N4 in pure water without any sacrificial reagent. Combining the experimental results and molecular dynamic (MD) simulation results, a possible mechanism can be drawn that the existed PEDOT possesses relatively higher hole mobility and can be used as a hole conductor between g-C3N4 and P3HT. Then, the photogenerated holes migration can be accelerated by PEDOT from the VB of g-C3N4 to the VB of P3HT. All those factors may benefit the synergy among g-C3N4, PEDOT and P3HT, which finally facilitates the rapid migration of photoinduced electron–hole pairs and eventually improves the photocatalytic H2 activity process of g-C3N4–PEDOT/P3HT with visible light. The present work may provide useful insights for designing a surface heterojunction composite photocatalyst with high photocatalytic activity for H2 production.
研究领域:
材料科学
·
化学
·
光催化
·
可再生能源
✓ 已验证
DOI
高影响因子
POWDER TECHNOLOGY
·
2024
·
IF 4.5
Liaoyuan Ouyang,Jingjie Wu,Zhiqiang Huang,Aleksandr E. Burdonov,Nadezhda V. Vchislo,Hongling Wang,Guichun He,Xinyang Yu,Jinpeng Ma,Wenyuan Li
How to flotation fine kaolinite efficiently is a challenge. For the improvement of fine kaolinite flotation recovery, a novel 3-tetradecylamine propyl amidoxime (TPA) collector was synthesized. In comparison to the conventional collector tetradecylamine (TDA), the fine kaolinite exhibited better floatability in the TPA system, with a recovery of 90.5% in micro-flotation experiments. It was indicated by contact angle tests that TPA was more effective in improving the hydrophobicity of kaolinite by increasing its contact angle from 24.5° to 85°. Fourier transform infrared spectroscopy (FTIR) indicated that the adsorption of TPA on kaolinite surface was by electrostatic interaction, and zeta potential tests showed a significant increase in the surface potential. In addition, it was learned that TPA interacts with the kaolinite surface more effectively than TDA by using density functional theory (DFT) calculation. Therefore, TPA with excellent performance is expected to be a novel and efficient fine kaolinite flotation collector.
研究领域:
矿物加工工程
·
表面化学
✓ 已验证
DOI
高影响因子
Microorganisms
·
2025
·Vol. 14
·期 1
·11
·
IF 4.2
Qianxin Lu,Huisha Du,Xin Jiang,Bingwen Zeng,Tianhui Li,Ying-Chun Dai
The GI.3 norovirus is the most detected and recombinant-rich genotype within genogroup I, yet the mechanistic basis for its epidemiological success remains poorly understood. This study integrates Bayesian evolutionary analysis with in vitro enzymology to investigate the link between RdRp function and the evolutionary dynamics of GI.3 NoV. We analyzed 831 GI.3 sequences, finding that prevalent strains (GI.3[P3] and GI.3[P13]) exhibited significantly higher evolutionary rates in both the RdRp and VP1 genes than non-prevalent strains (GI.3[P10] and GI.3[P14]). While the RdRp gene displayed a strong molecular clock signal, the VP1 gene’s evolution was more complex, showing cluster-specific trends. Functionally, the RdRps from prevalent strains demonstrated superior enzymatic activity and substrate affinity (Km: GI.3[P13] = 0.092 mM; GI.3[P3] = 0.176 mM) compared to non-prevalent strains (Km: GI.3[P14] = 0.273 mM). Notably, GI.3 RdRp required higher manganese ion concentrations for optimal activity than previously reported for GII strains, suggesting a potential biochemical constraint. Our findings demonstrate a clear correlation between RdRp enzymatic efficiency, evolutionary rate, and strain prevalence. We propose that a highly active RdRp may potentially accelerate VP1 evolution and confer a replicative advantage, underpinning the dominance of specific GI.3 lineages. This work provides crucial experimental evidence linking viral polymerase function to evolutionary and epidemiological outcomes.
✓ 已验证
DOI
PubMed
高影响因子
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