ELECTROANALYSIS
·
2021
·Vol. 33
·期 9
·2016-2024
·
IF 3.223
Yongliang Guo,Lili Tian,Jiangming Wu,Yang Wu,Yongmei Liu,Jie Du,Xiaoquan Lu
In this study, we found that spermine (SPM) could enhance electrochemiluminescence (ECL) intensity of Au−Ag bimetallic nanoclusters (Au−Ag BNCs) with triethylamine (TEA) as a co-reactant. An ECL sensor was fabricated to detect SPM, which contained Au−Ag BNCs as ECL emitters and conductive hydrogel containing polyaniline-amino trimethylene phosphonic acid (PANI-ATMP) as an immobilizing matrix. The increased ECL intensity of SPM was linear with the logarithm of concentrations of SPM in the range of 1 pM to 10 μM with high selectivity, excellent stability, and the limit of detection is 0.11 pM (S/N=3). This sensor realized the detection of SPM in urine samples, which was fast and economic, possessing potential applications for SPM detection in clinical and bioanalysis.
研究领域:
分析化学
·
生物医学
✓ 已验证
产品关联
DOI
高影响因子
ACS Omega
·
2021
·
IF 3.512
Qiuzheng Du,Ziwei Jing,Hang Qi,Lihua Zuo,Lin Zhou,Hua He,Zhi Sun
The work described a new colorimetric sensor for the quantitative detection of clindamycin based on Au@Ag core–shell nanoparticles (Au@Ag NPs). The obtained Au@Ag NPs were characterized by transmission electron microscopy (TEM) and ultraviolet and visible spectrophotometry (UV–vis). When Au@Ag NPs were added to a clindamycin solution, it can be observed that the color immediately changed from bright yellow to gray-blue and the absorption spectrum also changed, realizing the visual detection of clindamycin. Under optimal conditions, the absorption ratio (A546/A400) of the UV–vis spectra increased linearly with the concentration of clindamycin ranging from 6.25 × 10–7 to 7.50 × 10–6 mol/L (R2 = 0.9945), with a limit of detection (LOD) of 2.00 × 10–7 mol/L and good recovery of 100.0–102.0% (relative standard deviation (RSD) < 2%). The detection process was convenient without complicated instruments. Compared with other analytes, the Au@Ag NPs detection system has good selectivity for clindamycin. In addition, the Au@Ag NPs colorimetric sensor was successfully used to determine clindamycin in human urine samples. This study provides a simple, rapid, intuitive, and low-cost visualization analysis method of clindamycin, which was helpful for the visualization detection of other targets.
研究领域:
分析化学
·
纳米技术
·
药物分析
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials
·
2023
·Vol. 16
·期 3
·1169
·
IF 3.4
Qian Wei,Beibei Lu,Qing Yang,Can Shi,Yulan Wei,Minmin Xu,Chenjie Zhang,Yaxian Yuan
Fenton technology is one of advanced oxidation process (AOP) methods to treat wastewater through chemical oxidation. Due to the limitations of classical iron-based catalysts, it is still challenging to find suitable catalysts for Fenton-like reactions. Here, MoS2/Au heterojunctions were successfully synthesized by reduction of chloroauric acid in the solution of layered MoS2prepared by hydrothermal method. As a model molecule, methylene blue (MB) was used as the species to be degraded to evaluate the performance of the catalyst. It was determined by UV–visible spectra that the optimal catalyst can be obtained when MoS2(mg): HAuCl4(wt. % mL) is 2:2. The Fenton-like reaction process was monitored by introducing highly sensitive surface enhanced Raman spectroscopy (SERS). The results show that MB can be degraded by 83% in the first 10 min of the reaction, indicating that MoS2/Au has good catalytic performance. In addition, as a fingerprint spectrum, SERS was used to preliminarily analyze the molecular structure changes during the degradation process. The result showed that C-N-C bond was easier to break than the C-S-C bond. NH2group and the fused ring were destroyed at the comparable speed at the first 30 min. In terms of application applicability, it was showed that MB degradation had exceeded 95% at all the three pH values of 1.4, 5.0, and 11.1 after the reaction was carried out for 20 min. The test and analysis of the light environment showed that the catalytic efficiency was significantly improved in the natural light of the laboratory compared to dark conditions. The possible mechanism based on ·OH and ·O2−from ESR data was proposed. In addition, it was demonstrated to be a first-order reaction from the perspective of kinetics. This study made a positive contribution to broaden of the applicable conditions and scope of Fenton-like reaction catalysts. It is expected to be used as a non-iron catalyst in practical industrial applications. From the perspective of detection method, we expect to develop SERS as a powerful tool for the in situ monitoring of Fenton-like reactions, and to further deepen our understanding of the mechanism.Keywords:MoS2/Au heterojunctions;Fenton-like reaction;methylene blue;surface enhanced Raman spectroscopy
研究领域:
催化
·
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2021
·
IF 6.901
Jiankun Wei,Yidan Jing,Zelin Zhao,Zhengwen Fan,Zijia Liang,Junling Huang,Han Wu,Zhizhong Xie,Dan Liu,Deyu Qu,Haolin Tang,Junsheng Li
Electrochemical nitrogen reduction reaction (ENRR) is a promising supplement to the existing Haber-Bosch process due to its mild reaction condition and high theoretical efficiency. However, rational design of efficient ENRR catalyst remains to be the key challenge for the future development of practical ENRR process. In this work, we propose a strategy to enhance the performance of ENRR catalyst by catalyst-support interactions. This strategy is verified with Au/ZrO 2 catalyst. Both experimental and theoretical investigations show that electron is transferred from ZrO 2 substrate to Au. Such an electron transfer process modifies the electronic structure of Au, which enhances the ENRR activity HER performance of the Au active components. Benefiting from the catalyst-support interactions, the optimal Au/ZrO 2 catalyst shows a high ammonia yield of 54.84 μg h −1 mg −1 Au .
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry C
·
2019
·Vol. 7
·期 48
·15259-15268
·
IF 6.641
Lingling Zhang,Xiaodie Li,Weihua Liu,Rui Hao,Hongrui Jia,Yanzhu Dai,Muhammad Usman Amin,Hongjun You,Tao Li,Jixiang Fang
The fabrication of flexible surface-enhanced Raman scattering (SERS) substrates with high sensitivity and signal consistency in a simple and low-cost way have been a crucial and urgent challenge. In this study, we demonstrated a flexible transparent three-dimensional (3D) ordered micro-hemisphere (MHS) array PDMS film with self-assembled Au nanoparticles (NPs) (an Au NP-MHS array film) as a surface-enhanced Raman scattering (SERS) platform for the in situ detection of pesticides in food. According to the finite difference time domain (FDTD) simulation results, the Au NP-MHS array film possesses high-density and ordered “hot spots” to enhance the electromagnetic field (EMF), so that the sensitivity and signal consistency are effectively improved. The optimized Au NP-MHS array film exhibits fascinating SERS sensitivity, with a limitation of crystal violet (CV) reaching 10−12 M as well as excellent consistency (RSD = 4.89% at 10−8 M). For in situ pesticide detection in fruits, this flexible film was pasted on the surfaces of tomatoes. The carbendazol and parathion were directly detected, and distinctly identified even at a low concentration (10−8 M). The flexible Au NP-MHS array film could be a potential candidate for the SERS substrate applied in the rapid and true inspection.
研究领域:
材料科学
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分析化学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
Materials
·
2019
·Vol. 12
·期 12
·1978
·
IF 2.972
Wei Sun,Shaowen Huang,Siyu Zhang,Qi Luo
Nanomaterials extensively studied by nanotechnology scientists have been extensively applied in biomedicine, chemistry, physics and other fields nowadays. Magnetic nanoparticles, surpassing nano applications, are found to possess many advantages over nonmagnetic nanomaterials. Graphene oxide (GO), in particular, draws growing scholarly attention due to its large surface area, good water solubility and biocompatibility, rich surface functional group and easy-to-modify property. In this paper, we modify the Polyethylene mide (PEI) molecule on the surface of GO to increase its biocompatibility. The Au-Fe3O4nanoparticles and folic acid molecules on the ligand make the resulting composite applicable both in magnetic resonance imaging and in cancer cell targeting. In addition, the π-π accumulation of doxorubicin used to load the anticancer drug can release the drug under the acid condition of the cancer cells, detect the cancer cells by fluorescence and realize the multi-mode detection of cancer cells.Keywords:graphene oxide;Au-Fe3O4nanoparticles;targeting cancer cells;drug delivery
研究领域:
生物医学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2022
·
IF 7.129
Dandan Kong,Xinyue Li,Yang Tang,Ming Sui,Jinping Li,Yonggui Ma,Gaofeng Wang,Wei Gu,Xuegang Guo,Meihua Yang
Environmental pollution and medicine safety have aroused increasing public concerns due to human health. Amongst various contaminants, mercury is of special attention owing to their environmental persistence and biogeochemical recycling and ecological risks. Herein, a simple and highly parallel electrochemical biosensor for Hg determination was designed and investigated. The proposed biosensor was prepared and compared between (1) DTT/MB-DNA/Au with configuration occupation approach and (2) MCH/MB-DNA/Au with passivation approach. According to the combined results of scanning electrochemical microscope (SECM) and Randles-Sevcik equation, the DTT modified electrode exhibited high uniformity on DNA distribution and superb stability on electron transfer in Hg 2+ detection. Evidentially, the response value of proposed DTT/MB-DNA/Au was increased from 57.518% to 97.607%, while RSD% between duplicate runs had dropped from 22.658% to 0.223% (n = 3). Moreover, the increased proportion of effective working area was 467.380% compared with general sensors. Besides, DTT concentration, DNA concentration as well as assembly time were optimized, utilizing electrochemical impedance spectroscopy (EIS), Cyclic Voltammetry (CV) and Square Wave Anode Stripping Voltammetry (SWASV). This optimized biosensor exhibited an excellent selectivity toward Hg 2+ over Cu 2+ , As 2+ , Cd 2+ , Pb 2+ , Cr 3+ , Ni 2+ and Zn 2+ etc., and the stability of DTT/MB-DNA/Au were at least two times better even after 3 days under room temperature. Also, a linear relation was observed between the peak current and Hg 2+ concentrations in a range from 0.25 nM to 2.00 μM with a detection limit of 53.00 pM under optimal conditions. Finally, DTT/MB-DNA/Au was applied for plants and medical products analysis. In all, this optimized DTT/MB-DNA/Au with advantages of high repeatability and sensitivity would provide a new insight into the design and application of biosensor for reliable sensing in safeguarding plant protection and medicinal safety.
研究领域:
环境科学
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生物传感技术
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2025
·
IF 5.1
Yuxin Wu,Qi He,Heng Zhang,Xiaolin Meng,Yuanyuan Min,Yi Wang,Xiaohu Wu,Pu Zhang,Yanyun Ma,Yiqun Zheng
In-plane interface engineering of two-dimensional ultrathin CuS–Au and CuS@Au nanohybrids is realized, showcasing the potential in near-infrared photothermal conversion. The synthesis involves creating high-purity ultrathin CuS nanoplates, followed by controlled Au deposition on their edges in two patterns: a layer-by-layer approach for a seamless shell and an island-growth method for isolated nano-islands. This technique precisely manipulates the CuS–Au interface, enhancing their interaction and electronic structure. When irradiated with 808 nm and 1064 nm lasers at 0.4 W m−2, the optimized CuS–Au hybrids achieve photothermal conversion efficiencies of 67.31% and 32.02%, respectively, along with outstanding photothermal stability. Finite difference time domain (FDTD) simulations suggest that attaching spherical particles to the plate edges significantly boosts electric field strength and temperature distribution under NIR light. Additionally, CuS–Au HNPs-I demonstrated remarkable efficacy in killing prevalent clinical pathogens with 10-minute exposure to near-infrared light, achieving an impressive antibacterial efficiency of over 99.9%. This study provides a versatile strategy for the in-plane interface engineering of two-dimensional hybrid nanostructures, paving the way for efficient photothermal materials.
研究领域:
材料科学
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生物医学工程
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2019
·Vol. 35
·期 5
·924-928
·
IF 1.071
Xiang Siyuan,Meng Qingnan,Zhang Kai,Gu Yue,Liu Wendong,Yang Bai
Using dextran as both reductant and stabilizing agent, nanopetals(ZnO-Au NPs) were easily synthesized and possessed a petal-like morphology. The feature structure and size of such ZnO-Au NPs were adjustable by regulating the amount of chloroauric acid(HAuCl 4 ). Moreover, the electrochemical property of the obtained NPs was evaluated by being immobilized on the glassy carbon electrode(GCE), which performed both high sensitivity and stability in dopamine(DA) determinations. Furthermore, the as-prepared ZnO-Au NPs could also detect DA and uric acid(UA) simultaneously in the mixture without interference, indicating good selectivity and showing promising potential in biosensing.
研究领域:
材料科学
·
生物传感
·
分析化学
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2018
·
IF 4.439
Yuxue Zhou,Pengfei Lv,Wei Zhang,Xiangdong Meng,Hui He,Xianghua Zeng,Xiaoshuang Shen
Pristine Bi 2 WO 6 hollow microspheres have been fabricated in ethylene glycol-water system with CTAB as crystal growth director for the first time, hybrid Au- Bi 2 WO 6 hollow microspheres was also obtained by in situ decoration of Au nanoparticles, the formation mechanisms were explored. Their photocatalytic activities on photo-reduction of Cr(VI) and photo-degradation of phenol in aqueous solution were investigated under visible light irradiation. Hybrid Au- Bi 2 WO 6 hollow microspheres displayed the highest photocatalytic activity, exhibiting a nearly complete reduction of Cr(VI) to Cr(III) within only 20 min. The excellent photocatalytic activities of heterogeneous Au-Bi 2 WO 6 hollow microspheres can be induced by the increased light harvesting efficiency (due to light multi-scattering effect of hollow architecture), high separation of photogenerated electron-hole pairs caused by electron trapping effect and surface plasmon resonance (SPR) effect of Au nanoparticles.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2021
·
IF 6.986
Danli Hu,Haiyan Cui,Xinyang Wang,Fang Luo,Bin Qiu,Weicheng Cai,Hui Huang,Jian Wang,Zhenyu Lin
An Au/GaN photoelectrode was prepared by sputtering 30 nm thick Au film on the surface of n-type gallium nitride (GaN). When the electrode contacts with multilayered molybdenum disulfide (MoS2), photogenerated electrons and photogenerated holes transfer to MoS2 because of the band gap matching of MoS2 and GaN. The presence of Au promotes charge transfer and results in a greater recombination of electrons and holes; by this means, a more significant suppression of photocurrent can be detected. This characteristic has been coupled with the high selectivity of an aptamer and applied to develop a novel photoelectrochemical aptasensor for cancer biomarkers (alpha-fetoprotein (AFP) as a model). The aptamer of AFP was modified on the surface of the Au/GaN photoelectrode by Au–S bonds, which can bind to the target protein with high selectivity. Then, the transfer process of the charge carriers of GaN to MoS2 can be blocked by the target protein so that the suppression of photocurrent is reduced. The difference of the photocurrent in the presence and absence of AFP (ΔI) showed a linear relationship with AFP concentration that ranged from 1.0–150 ng/mL (R2 = 0.9995), and the detection limit was 0.3 ng/mL. The standard addition recovery rates ranged from 85.2 to 91.7%. The method possessed good sensitivity and high selectivity for AFP detection. The developed biosensor can be modified to detect other cancer biomarkers by simply replacing the aptamer used.
研究领域:
生物传感技术
·
癌症诊断
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Peng Wang,Tao Dong,Changchao Jia,Ping Yang
ZnO flowers with thin sheet and hemisphere shapes were fabricated via thermal decomposition in an organic solvent. Especially, typical hemisphere morphology with exposed (002) crystal face were created for the first time. Because of exposed (002) facet increased, a facet-like heterostructure of ZnO formed to get enhanced sensor performance, especially after loading Au nanoparticles (NPs) using a supersonic chemistry way. Gas sensing tests indicate that the hemisphere Au/ZnO sensor with the best performance and a nice selectivity to acetone. This is ascribed that the unique second-level structure provides more active centers and diffusion channels for acetone molecules. Au NPs increases the thickness of the surface electron depletion layer, which enhanced the sensitivity of the gas sensor.
研究领域:
材料科学
·
传感器技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）