JOURNAL OF MOLECULAR LIQUIDS
·
2022
·
IF 6.633
Hang Li,Qingsheng Zhao,Senlin Chang,Liwei Wang,Bing Zhao
Industrial hemp is an important economic crop. The extract of its leaves is well-known as cannabidiol full-spectrum oil (CFSO) and has great application potential. But the chemical composition of CFSO is still not clear, which limits its efficient application. Therefore, this work aimed to explore the phytochemical profile and composition-activity relationship of CFSO. The results showed that a total of 12 cannabinoids were identified by HPLC-ESI-MS and they were CBD-C 1 , CBGVA, CBGA, CBGV, CBDVA, CBG, CBDV, CBDA, CBD, CBD-C 4 , CBN, and CBT. CBD (559.3 mg/g) was the most abundant component, followed by CBDV (302.4 mg/g) and CBN (31.7 mg/g). Besides, the content of CBDV, CBD, and CBN of different polar extracts increased with the rise of ethanol concentration. The TPC and TFC of the extracts also increased with the rise of ethanol concentration. The extract of 90 % EtOH had the highest TPC (949.21 ± 2.37 mg GAE/g extract) and TFC (267.05 ± 1.21 mg RE/g extract) while the extract of 0 % EtOH displayed the lowest TPC (244.89 ± 2.13 mg GAE/g extract) and TFC (46.26 ± 0.85 mg RE/g extract). Furthermore, as ethanol concentration increased, the cytotoxicity, antioxidant, and antibacterial activities of the extracts had a significant increasing trend. And the correlation analysis demonstrated that the antioxidant activity and cytotoxicity of the extracts were closely related with the phenolic compounds and flavonoids, especially cannabinoids. These findings could provide data support for the application of CFSO.
研究领域:
药理学
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化学
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植物科学
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分析化学
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产品关联
DOI
高影响因子
FOOD AND BIOPRODUCTS PROCESSING
·
2024
·
IF 3.5
Meiling Huang,Chunling Lai,Yan Liang,Qin Xiong,Chaoyun Chen,Zhiran Ju,Yueming Jiang,Jun Zhang
The fermentation of navel orange juice with lactic acid bacteria (LAB) has rarely been investigated. In this study, an autochthonous LAB strain isolated from navel orange, Lactiplantibacillus paraplantarum M23, was found to effectively ferment navel orange juice, producing a juice with enhanced functional activities and organoleptic quality. The viable bacterial count in the fermented orange juice remained consistently above 8.51 log CFU/mL throughout the entire 7-day fermentation period. The content of vitamin C (VC), total phenolic content (TPC), total flavonoid content (TFC), and hesperidin in the fermented orange juice increased by a maximum of 28.88, 1.21, 1.13, and 1.16 times, respectively, compared to the unfermented orange juice. The fermented juice exhibited significantly higher antioxidant activity than the unfermented juice, with an increase of up to 255 % and 347 % based on 1,1-diphenyl-2-picrylhydrazyl (DPPH) and ferric ion reducing antioxidant power (FRAP) assays, respectively. This may be attributed to the increase in VC and flavonoids, as demonstrated by Pearson's correlation analysis. Additionally, the fermented orange juice demonstrated improved α-glucosidase inhibition, anti-MRSA, and anti-glycation activities compared to the unfermented juice. Furthermore, the fermented juice notably reduced the levels of NO and ROS in Raw 264.7 cells without any negative impact on cell viability. The findings of this study may help in the development of nutritious and healthy fermented navel orange juice products, and serve as a reference for the production of fermented beverages from other fruits using autochthonous strains.
研究领域:
食品科学
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微生物学
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营养学
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生物化学
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2020
·
IF 3.99
Miaolu He,Lei Wang,Yongtao Lv,Xudong Wang,Zhe Zhang,Qi Cui,Jiani Zhu
A thin-film composite (TFC) membrane with hydrophilic double-skinned support layer was developed to improve anti-fouling performance. The double-skinned separate casting technology was applied to obtain the double-skinned support layer and the polyacrylonitrile (PAN) concentration in the bottom casting solution was adjusted. Then, the support layer was carboxylated by immersing in a 1.5 M NaOH solution for 2 h. Finally, TFC membrane with hydrophilic double-skinned support layer was obtained by the interfacial polymerization. When the PAN concentration in the bottom casting solution was 10 wt%. TFC membrane with hydrophilic double-skinned support layer (TFC-10 %) showed the best performance. The water flux of TFC-10 % reached 17.6 LMH and the reverse salt flux was 5.6 gMH. Under the double interception effect of the double-skinned structure and the steric hindrance of the hydration layer on the support layer, good anti-fouling property of TFC-10 % was observed under bovine serum albumin (BSA) foulant. Compared to the traditional TFC membrane, the normalized flux of TFC-10 % increased by 80 %. The anti-fouling performance was also analyzed by microaction mechanisms using AFM and QCM-D. It was found that the adhesion force between TFC-10 % and BSA was small, therefore fewer pollutants were adsorbed on TFC-10 %, and its adsorption layer was loose and easy-cleaning.
研究领域:
膜科学
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水处理
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材料科学
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产品关联
DOI
高影响因子
DESALINATION
·
2022
·
IF 11.211
Yi-Xin Wang,Cheng-Ye Zhu,Jingliang Huang,Hao-Cheng Yang,Zhi-Kang Xu
Thin-film composite (TFC) membranes can find broad uses in desalination and wastewater treatment . However, industrialized interfacial polymerization involves many organic solvents and toxic monomers . An aqueous fabrication process can meet the standards of green and sustainable production, but fabricating defect-free thin films in a homogenous phase remains challenging. Herein, we fabricate a series of TFC nanofiltration membranes through a contra-diffusion process based on the cross-linking of metal ions and alginate . The film formation is confined at the ultrafiltration substrate surface due to the competition between reaction and restricted diffusion. Among a series of metal ion/alginate composites, the Cu 2+ /alginate composite membrane displays superior nanofiltration performance because of the strong affinity between Cu 2+ and alginate. The highly negatively charged membrane performs a high rejection to divalent anions and anionic dyes based on the Donnan effect . The effects of alginate concentration and diffusion time on membrane performance were investigated to achieve optimal fabrication conditions. The as-prepared membrane shows a rejection of 96.2% to Na 2 SO 4 with permeation flux around 50.2 L·m −2 ·h −1 under 0.6 MPa, and 99.5% to several dye molecules. Moreover, the membrane performs outstanding anti-fouling and anti-bacterial properties because of its excellent hydrophilicity and the existence of Cu 2+ .
研究领域:
环境科学
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材料科学
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化学工程
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水处理
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产品关联
DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2023
·
IF 8.1
Ruihong Dong,Mengting Zhu,You Long,Qiang Yu,Chang Li,Jianhua Xie,Yousheng Huang,Yi Chen
This study evaluated chemical compositions of green coffee beans from multi-production regions and correlated this information with thermal contaminants in roasted coffee. Using multivariate statistical techniques, formation of 5-hydroxymethylfurfural (5-HMF), furan, 2- and 3-methylfuran were positively correlated with lipid, sucrose, glutamic acid, phenylalanine, margaric acid, linolenic acid and trigonelline in green coffee beans. Moreover, significant positive correlations between acrylamide (AA) levels with aspartic acid, serine, alanine, histidine, asparagine, protein, and caffeine was found in green beans. Despite this, 5-HMF, furan, 2- and 3-methylfuran showed negative correlations with active constitutes (neochlorogenic acid, cryptochlorogenic acid, caffeine, total phenolics (TPC) and total flavonoids contents (TFC)), and several amino acids, and there were slight negative relationships between AA and myristic acid, palmitic acid, chlorogenic acid, sucrose, lipid, TPC and TFC. This study provides valuable enlightenment for the selection of proper coffee beans for production of coffee with high nutrition and low chemical hazardous risks.
研究领域:
食品科学
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分析化学
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营养学
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产品关联
DOI
PubMed
高影响因子
Science Advances
·
2024
·Vol. 10
·期 32
·
IF 11.7
Ayan Yao,Junjun Hou,Pengjia Dou,Jingcheng Du,Qian Sun,Ziye Song,Linghao Liu,Jian Guan,Jiangtao Liu
Thin-film composite (TFC) membranes have gradually replaced some traditional technologies in the extraction, separation, and concentration of high value-added pharmaceutical ingredients due to their controllable microstructure. Nevertheless, devising solvent-stable, scalable TFC membranes with high permeance and efficient molecule selectivity is urgently needed to improve the separation efficiency in the separation process. Here, we propose phenolphthalein, a commercial acid-base indicator, as an economical monomer for optimizing the micropore structure of selective layers with thickness down to 30 nanometers formed by in situ interfacial reactions. Molecular dynamics simulations indicate that the polyarylate membranes prepared using three-dimensional phenolphthalein monomers exhibit tunable microporosity and higher pore interconnectivity. Moreover, the TFC membranes show a high methanol permeance (9.9 ± 0.1 liters per square meter per hour per bar) and small molecular weight cutoff (≈289 daltons) for organic micropollutants in organic solvent systems. The polyarylate membranes exhibit higher mechanical strength (2.4 versus 0.8 gigapascals) compared to the traditional polyamide membrane.
研究领域:
材料科学
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化学工程
·
膜技术
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产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2019
·
IF 1.911
Yazhi Yang,Qianqian Lan,Yong Wang
Thin film composite (TFC) membranes represent a highly promising platform for efficient nanofiltration (NF) processes. However, the improvement in permeance is impeded by the substrates with low permeances. Herein, highly permeable gradient phenolic membranes with tight selectivity are used as substrates to prepare TFC membranes with high permeances by the layer-by-layer assembly method. The negatively charged phenolic substrates are alternately assembled with polycation polyethylenimine (PEI) and polyanion poly(acrylic acid) (PAA) as a result of electrostatic interactions, forming thin and compact PEI/PAA layers tightly attached to the substrate surface. Benefiting from the high permeances and tight surface pores of the gradient nanoporous structures of the substrates, the produced PEI/PAA membranes exhibit a permeance up to 506 L ∙ m −2 ∙ h −1 ∙ MPa −1 , which is ~ 2–10 times higher than that of other membranes with similar rejections. The PEI/PAA membranes are capable of retaining > 96.1% of negatively charged dyes following the mechanism of electrostatic repulsion. We demonstrate that the membranes can also separate positively and neutrally charged dyes from water via other mechanisms. This work opens a new avenue for the design and preparation of high-flux NF membranes, which is also applicable to enhance the permeance of other TFC membranes.
研究领域:
材料科学
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纳米技术
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膜技术
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环境工程
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产品关联
DOI
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2019
·Vol. 99
·期 12
·5565-5576
·
IF 2.422
Yongxiang Liu,Chunzhi Cai,Yiliang Yao,Baojun Xu
BACKGROUND Buckwheat products are receiving increasing attention because of their high nutritive values and significant health-promoting properties. In the present study, 15 buckwheat products grown in different parts of China were investigated. Representative common or tartary buckwheat samples were further subjected to soaking, roasting, microwave cooking, boiling and steaming treatments. Colorimetric analyses and high-performance liquid chromatography (HPLC) analyses were performed to determine the phenolic profiles and antioxidant capacities of the raw and thermally processed buckwheat samples, respectively. RESULTS Tartary buckwheat exhibited a remarkably higher total phenolic content (TPC), total flavonoid content (TFC), 2-diphenyl-1-picryhydrazyl (DPPH) free radical scavenging activity and ferric reducing antioxidant power (FRAP) compared to common buckwheat, although there were no significant differences between their 2,2′-azino-di-(3-ethylbenzthiazoline sulfonic acid) (ABTS) free radical scavenging capacity. All thermal treatments, particularly microwave cooking, contributed to the greatest losses of phenolics and antioxidant capacities in the common buckwheat samples, whereas boiling and steaming usually resulted in the lowest losses. For the tartary buckwheat samples, all thermal treatments (except roasting), especially boiling and steaming, led to significant increases in TPC, TFC, DPPH free radical scavenging activity, FRAP and ABTS free radical scavenging capacity. However, HPLC analyses indicated that all thermal treatments, especially microwave cooking, gave rise to the greatest losses of the total content of 14 phenolic acids and three flavonoids, whereas boiling led to the lowest losses. CONCLUSION Both steaming and boiling treatments are recommended when preparing common or tartary buckwheat food products because they can minimize thermal degradation or promote their phenolic compounds and antioxidant capacities to the greatest extent. © 2019 Society of Chemical Industry
研究领域:
食品科学
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营养学
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化学工程
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农业
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF FOOD BIOCHEMISTRY
·
2020
·Vol. 45
·期 3
·e13183
·
IF 1.662
Mengke Wang,Xing Liu,Zejie Zhang,Jiawen Yu,Jiajia Liu,Yiqiang Wu
This paper aims to investigate the constituent phytochemicals and biological activities of six Lithocarpus litseifolius (Hance) Chun ( L. litseifolius ) cultivars. Processed by UPLC-MS/MS and untargeted metabolomics analysis software (MS-DIAL and MS-FINDER), components of different L. litseifolius cultivars were analyzed qualitatively and quantitatively. By conducting a comprehensive analysis of spectra, MS/MS fragmentation, and retention time, 40 compounds (including 6 phenolic glycosides and 34 flavonoids) were identified rapidly and accurately. Moreover, the total phenolic content (TPC), total flavonoid content (TFC), antioxidant, antimicrobial effects, and pheochromocytoma (PC12) cell viability of different L. litseifolius varieties were evaluated. Purple small leaf (PSL) was found to be the most superior variety with the highest antioxidant activities (8.27, 10.09, and 10.80 mg TE/g for DPPH, ABTS, and FRAP assays, respectively), broad-spectrum antimicrobial activity, and lowest cell cytotoxicity. The results showed that these bioactivities were closely related to phytochemicals among the six cultivars. Practical applications L. litseifolius is well known as an important folk drink in the Southern China folklore for its specific efficacy in preventing diabetes. However, there is still a paucity of information on L. litseifolius , as other active components and bioactivities of it remain to be investigated. The wide range of flavonoids discovered in L. litseifolius provides abundant natural health-promoting agents for further applications in medicine and functional food.
研究领域:
药用植物学
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分析化学
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植物科学
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功能食品
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药用植物
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2021
·
IF 8.742
Junwen Ding,Heng Liang,Xuewu Zhu,Daliang Xu,Xinsheng Luo,Zihui Wang,Langming Bai
Nanofiltration (NF)-based brackish water desalination has been labeled an emerging avenue for alleviating water scarcity, however, membrane fouling still restricts its broad application. Herein, zwitterion-modified membranes were prepared with polydopamine (PDA) and sulfobetaine methacrylate (SBMA) monomers via surface-initiated atom-transfer radical-polymerization (SI-ATRP) and named TFC-PDA-PSBMA. Compared with the control membrane, the TFC-PDA-PSBMA possessed enhanced hydrophilicity, lower negative charge and smaller pore size. Superior salt retention of Na 2 SO 4 and NaCl of up to 99.1% and 80.7% was obtained for TFC-PDA-PSBMA with only a 10% decrease in permeance. Furthermore, TFC-PDA-PSBMA exhibited an outstanding flux recovery of 92.1% during humic acid (HA) filtration. The mechanism driving the improved antifouling properties was analyzed from the aspects of the modified layer, free interfacial energy and hydration layer. TFC-PDA-PSBMA also exhibited superior antibiofouling with reducing 86.1% of E. coli colonies adhered on membrane surface. The SBMA layer and hydration layer acted together as a buffer layer with robust repulsion of foulants. In addition, the TFC-PDA-PSBMA membrane was applied in authentic brackish water desalination and exhibited superior selectivity, desalination and antifouling performance, which matched the simulated solution results well. A new concept of a “buffer layer” was proposed in this work, which may provide insight into antifouling membrane design during brackish water treatment.
研究领域:
水处理
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膜科学
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环境工程
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材料科学
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Jiao Wu,Xiang-Tan Xu,Cheng Xing,Xin-Bao Hao,Xing-Yue Fang,Zhi-Hao Xie,Shan Zhao,Jing-Lin Gao,Lu Xu,Shi-Jie Wang
Honey has been recognized for its role in disease prevention through nutritional modulation. In this study, we comprehensively assessed the physicochemical parameters, metabolic profile, antioxidant and anti-inflammatory activities of multifloral honeys produced by Apis cerana cerana in Sansha City (SS), Hainan Province. Metabolomic analysis identified SS honey had multiple bioactive compounds known for antioxidant and anti-inflammatory properties. Compared to A. cerana cerana honey from central regions of Hainan Province, SS honey showed higher levels of TFC (113.80 mg RE/100 g) and TPC (45.86 mg GAE/100 g). Furthermore, SS honey demonstrated greater antioxidant activity, as evidenced by FRAP (1503.16 μmol TE/kg), DPPH IC 50 (36.13 mg/mL), and ABTS IC 50 (11.03 mg/mL). SS honey significantly reduced the levels of cyclooxygenase-2 (COX-2), interleukin-1β (IL-1β), interleukin-6 (IL-6), inducible nitric oxide synthase (iNOS), and tumor necrosis factor-α (TNF-α) in lipopolysaccharide (LPS)-induced RAW 264.7 cells, along with suppressing the mRNA expression of these inflammatory markers.
研究领域:
养蜂学
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生物化学
·
药理学
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营养科学
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代谢组学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）