Molecular Catalysis
·
2018
·
IF 0
Xia Chen,Xu Ye,Wen-Yu Liang,Qing Zhou,Giang Vo-Thanh,Ye Liu
The unique amphiphilic Zwitterionic P,O-hybrid ligand ( L1 ) containing phosphino-fragment and −SO 3 − group was synthesized and firstly applied in Au-catalyzed hydration of alkynes. Without the aid of any auxiliary additive such as acid or silver salt, L1 -based Au-catalyst exhibited excellent activity towards hydration of alkynes to yield ketones with 100% selectivity according to Markovnikov’s rule. On the other hand, L1 -based Au-catalyst could be recycled for 4 runs in room temperature ionic liquid of [Bmim]PF 6 without obvious activity loss, and also exhibited wide generality to the hydration of different alkynes.
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ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Jian Zhao,Zhuo-Hao Jiao,Sheng-Li Hou,Yue Ma,Bin Zhao
Carboxylative cyclization of propargylic alcohols with CO2 is significant in synthetic chemistry, but harsh conditions are often needed according to reported results. Herein, a new stable nitro-functionalized metal–organic framework (MOF) of {[Co3(L)2(bpy)4(H2O)2]·DMF·H2O·bpy}n (1) was fabricated through the solvothermal reaction, which exhibited excellent stability in acid and basic solutions. Owing to the porous structure, unsaturated metal sites, and uncoordinated 4,4′-bpy ligands, 1 can serve as an excellent platform for catalytic applications. Hence, Ag(I) ions were incorporated in 1 through a postsynthetic method, and the as-synthesized Ag-1 catalyst with low metal loading (0.64 mol %) displayed excellent catalytic performance in the chemical fixation of CO2 with alkynols under room temperature and atmospheric pressure. The results of 1H NMR analyses further confirmed that Ag-1 can efficiently activate hydroxyl groups and promote the reaction. Moreover, the turnover frequency (TOF) of the Ag-1 catalyst can reach 262 h–1 in a short period of time, which is a high TOF value among the state-of-the-art MOF-based catalysts for catalyzing cycloaddition of CO2 with propargylic alcohols.
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FOOD CHEMISTRY
·
2019
·
IF 5.399
Qiumin Ye,Xiaohui Chen,Jing Yang,Datong Wu,Jianfeng Ma,Yong Kong
In this study, a sensitive and selective electrochemical sensing platform for the detection of Sudan I was developed with CuO nanoparticles-decorated 3D N -doped porous carbon (CuO/3DNPC). 3D N -doped porous carbon (3DNPC) was first prepared by calcining the precursors of 3D integrated polysaccharides, and then it was decorated with CuO nanoparticles by hydrothermal method. The CuO/3DNPC modified electrode showed high sensitivity and wide linear range for the detection of Sudan I due to the excellent electrocatalytic activity of CuO and the accelerated electron transfer by 3DNPC. In addition, the proposed CuO/3DNPC also exhibited high selectivity, high reproducibility and stability in the detection of Sudan I. Finally, the CuO/3DNPC based Sudan I sensor was applied in the detection of Sudan I in ketchup and chilli sauces, and the results demonstrated the potential of the developed CuO/3DNPC as a promising electrode material for accurate assay of Sudan I in food samples.
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PubMed
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JOURNAL OF ORGANIC CHEMISTRY
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2020
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IF 4.335
Lujia Mao,Chunlei Li,Libo Xiang,Dejun Fu,Wangyang Ma,Qing Ye
The synthesis of allenyl-Bdan has been realized via the Cu(I)-catalyzed borylation of propargylic alcohols. This methodology offers a facile and efficient pathway toward allenyboronates with diverse functional groups due to the simple access to the substrates. The substrates bearing ester groups are well-tolerated in the synthesis of allenyl-Bdan under the Lewis acidic conditions. The structures of two allenyl-Bdan were further confirmed via single-crystal X-ray diffraction.
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FOOD HYDROCOLLOIDS
·
2022
·
IF 11.504
Weiwei Hu,Huan Cheng,Dongmei Wu,Jianle Chen,Xingqian Ye,Shiguo Chen
The rhamnogalacturonan I (RG-I) region of pectin shows health benefits and novel gel applications. Commercial pectin is extracted from citrus peel in most instances, whereas they are homogalacturonan (HG)-dominated productions and the methods to extract pectin targeting RG-I are limited. To take full advantage of citrus wastes and upgrading this pectin resources, a new extraction method based on a diluted NaOH assisted by a combination of ultrasound (US) and pressure, namely manosonication (MS), was established for RG-I enriched pectin extraction. MS significantly enhanced the pectin yield (21.47 ± 0.11%) while reducing the use of NaOH reagents (50 mmol/L) and processing time (50 min). Structurally, the MS (300 kPa) resulting products achieved nearly a 2-fold greater RG-I content (58.61 mol%) than that of commercial pectin (30.12 mol%). Moreover, for the investigation of the extraction mechanism, external pressure enhanced the cavitation effect, as the calorimetric intensity increased from 1.28 W/mL (100 kPa) to 3.3 W/mL (350 kPa). A sufficient ultrasonic mechanical action allowed for obtaining RG-I enriched products with large molecular weight (9.506 × 10 4 –2.813 × 10 5 ) and low degree of methoxylation. Transmission electron microscopy (TEM) and scanning electron microscopies (SEM) verified the increased disintegration of the cell wall tissue by MS. Raman imaging and immunofluorescence labeling suggested the synergistic effect of pressure and ultrasound on enhancing the yields and RG-I content. This new method provided alternations in functional polysaccharides extraction, and the yield and structure of citrus RG-I enriched pectin strongly indicates the potentials of MS in other RG-I rich vegetables applications.
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Journal of Materials Chemistry A
·
2018
·Vol. 6
·期 19
·8930-8939
·
IF 9.931
Yu-Xia Li,Shuai-Shuai Li,Ding-Ming Xue,Xiao-Qin Liu,Meng-Meng Jin,Lin-Bing Sun
Cu(I)-containing materials have great potential in various applications such as in CO adsorption; however, development of an efficient and controllable method to produce Cu(I) sites remains a significant challenge; herein, a two-step double-solvent (DS) strategy is reported for the first time to fabricate Cu(I) sites in a representative metal–organic framework, MIL-101(Cr); this strategy ensures that both introduction of the Cu(II) precursor and its reduction to Cu(I) occur inside the pores and significantly minimizes the aggregation of Cu species. This is difficult to realize through conventional methods used for Cu(II) introduction (wet impregnation) or reduction (liquid-phase reduction). The two-step DS strategy involves selective reduction of Cu(II) to form Cu(I) without the formation of any Cu(0). The obtained Cu(I)-containing materials exhibit an excellent CO adsorption capacity (up to 2.42 mmol g−1) at 298 K and 1 bar, much better than that of the benchmark adsorbents including CuCl/γ-Al2O3 (1.0 mmol g−1), CuCl/MCM-41 (0.57 mmol g−1), and CuZSM-5 (0.11 mmol g−1).
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JOURNAL OF ANALYTICAL CHEMISTRY
·
2024
·Vol. 79
·期 5
·595-600
·
IF 1
An Hongde,Xie Bo,Luo Duqiang
Abstract The development of facile, sensitive, and robust methods for the detection of metal ions is fascinating for chemists because traditional strategies for their detection usually involve complicated instrumentation and critical sample preparation procedures. In this work, bicinchoninic acid was used in a specific reaction with Cu(I) for the spectrophotometric determination of various metal ions. The optimization of experimental parameters led to the establishment of a simple, fast, and accurate analytical method. Mn(II), Co(II), and Fe(II) can be detected at submicromolar levels using this method. Calibration graphs for Mn(II), Co(II), and Fe(II) are rectilinear within the range of 8–40, 15–150, and 15–150 μM, respectively. The detection limit for Mn(II), Co(II), and Fe(II) were 0.83, 1.4, and 1.9 mg/L, respectively, and the relative standard deviation did not exceed 2.5% for five replicates. The bathocuproine reaction demonstrated that Cu(II) can be reduced to Cu(I) by Mn(II). Then bicinchoninic acid can bind to Cu(I), creating a purple-colored product at 562 nm. The method has been successfully applied to evaluate the reaction process and stability of metal-organic frameworks. Moreover, the results were found to be in satisfactory agreement with those acquired by using the inductively coupled plasma mass spectrometry technique, which will open up a new avenue for using the proposed strategy as a conventional method to detect metal ions in scientific research.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Qiangyu Zhao,Zhenyuan Zhao,Renzhi Rao,Yang Yang,Songyuan Ling,Fukun Bi,Xiaoyu Shi,Jingcheng Xu,Guang Lu,Xiaodong Zhang
In this paper, a simple solvothermal synthesis method was proposed for the preparation of metal organic framework/graphene oxide hybrid nanocomposite (UiO-67/GO). A series of UiO-67/GO composites were prepared by varying the addition forms and amounts of GO, and the optimal synthesis conditions were screened. The composites were characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR), transmission Electron Microscope (TEM), scanning electron microscopy (SEM), X-ray photoelectron spectroscopic (XPS), water contact angles (CA) and thermogravimetric analysis (TGA). The adsorption capacity and the adsorption process of toluene were investigated by dynamic adsorption and adsorption kinetics , respectively. The results indicated that 67/GO-0.5% reached the maximum adsorption capacity (876 mg g −1 ), which far exceeded the other adsorbents. Kinetic model and the Weber-Morris model correlated satisfactorily to the experimental data. The improved adsorption performance was attributed to GO, which enhanced π-π interaction, promoted defect generation and provided more adsorption sites. Finally, the excellent regeneration performance of the adsorbent was verified by temperature programmed desorption (TPD) and cyclic adsorption–desorption experiments. Moreover, the adsorption mechanism was further revealed. Combined with the related adsorption experiments and the density functional theory (DFT) analysis, the efficient removal of toluene by UiO-67/GO was attributed to the cooperation of defects, π-π interaction and hydrogen bonding .
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Advanced Optical Materials
·
2025
·
IF 7.2
Lin Shi,Junchun Li,Zengce Liu,Ping Chen,Yang Jiang
Rare-earth metal halides have emerged as a compelling class of luminescent materials, offering an environmentally benign alternative to toxic lead-based halides. This work reports the successful synthesis of Cs 3 CeX 6 (X = Cl, Br, I) with tunable emission and excellent photoluminescence quantum yield (PLQY) of Cs 3 CeCl 6 . Through controlled halogen substitution in the Cs 3 CeX 6 (X = Cl, Br, I) system, composition-dependent emission redshift (Cl→Br→I) is observed. Among them, Cs 3 CeCl 6 achieves a photoluminescence quantum yield (PLQY) of 99.89%, significantly surpassing the 92.57% PLQY of Cs 3 CeBr 6 and the 7.53% PLQY of Cs 3 CeI 6 , meanwhile surpassing that of most previously reported lead-free metal halides, highlighting its exceptional potential for efficient luminescent applications. Thermal stability analysis reveals that Cs 3 CeCl 6 maintains remarkable emission efficiency at elevated temperatures, retaining > 85% of its room-temperature luminescence intensity at 438 K, compared to only 60% for Cs 3 CeBr 6 and a mere 10% for Cs 3 CeI 6 . The exceptional thermal robustness originates from their characteristically high activation energies for thermal quenching, which effectively suppress non-radiative relaxation pathways. White light-emitting diodes (LEDs) based on Cs 3 CeI 6 exhibit a remarkable color rendering index (R a ) of 95.1, in contrast to those based on Cs 3 CeCl 6 (R a = 77.6) and Cs 3 CeBr 6 (R a = 79.6); all WLEDs based on Cs 3 CeX 6 (X = Cl, Br, I) demonstrate excellent atmospheric stability. With near-unity PLQY and remarkable thermal stability of Cs 3 CeCl 6 , coupled with the outstanding white LEDs performance of Cs 3 CeI 6 , Cs 3 CeX 6 (X = Cl, Br, I) compounds emerge as promising candidates for next-generation environmentally friendly optoelectronic applications, particularly in advanced display technologies and solid-state lighting systems. This work contributes to the advancement of eco-friendly emitters with both high efficiency and practical utility in next-generation optical technologies.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2025
·
IF 3.8
Gao Hongfan,Zhang Shujing,Li Xin
Biotinylated antibodies are widely used in ELISA. However, their preparation typically requires labor-intensive purification steps to remove the excess biotinylating reagent. Here, we present a novel one-pot, purification-free strategy for preparing biotinylated antibodies, enabling a robust sandwich ELISA platform for the detection of the cardiac troponin I-C complex, a key biomarker for acute myocardial infarction. By introducing glycine (Gly) as a quenching agent to inactivate the residual biotinylating reagent (NHS-biotin esters) during the labeling process, our method eliminates the need for post-labeling purification while effectively reducing nonspecific background. Systematic optimization of labeling conditions yielded an assay with a detection limit of 1.08 pM and a broad linear quantification range from 3.6 pM to 1 nM ( R 2 = 0.99). The platform demonstrated high specificity, with recovery rates ranging from 91.5 to 101.8% and intra-assay variation below 2.9%. Furthermore, successful validation in a serum amyloid A detection model confirmed the generalizability of the Gly-mediated background suppression strategy. This cost-effective, streamlined ELISA workflow offers a powerful tool for rapid and reliable clinical diagnostics, with potential for broad application in biomarker detection. Graphical abstract This schematic contrasts the conventional and novel one-pot strategies for antibody biotinylation in ELISA. The traditional method requires a cumbersome purification step to remove excess biotin-NHS reagent after labeling. In contrast, our one-pot approach introduces a key innovation: an in-solution quenching reaction. The addition of a small molecule (e.g., glycine) efficiently inactivates residual biotin esters, allowing the biotinylated antibody to be used directly in subsequent steps, thereby streamlining the workflow.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Rui Zhou,Miao Dong,Yiwei Wu
N, Si, S co-doped graphene quantum dots (N, Si, S-GQDs) were synthesized from waste toner and glutathione (GSH) via a one-pot hydrothermal method. Combined with o-phenylenediamine (OPD), a rapid, visual, and autocatalytic ratiometric fluorescence sensor of N, Si, S-GQDs/OPD was fabricated for detecting Ag(I) and Fe(III) ions by producing 2,3-diaminophenazine (oxOPD) under pH 8, which emits yellow fluorescence at 560 nm while quenching the blue fluorescence of N, Si, S-GQDs at 440 nm due to an inner filter effect. With the increase of Ag(I)/Fe(III), the blue fluorescence of N, Si, S-GQDs at 440 nm was gradually weakened, along with the enhancement of yellow fluorescence at 560 nm. Hence, this color change from blue to yellow under UV light enables semi-quantitative visual detection. The sensor demonstrates high sensitivity with detection limits of 0.016 µg mL −1 for Ag(I) and 0.010 µg mL −1 for Fe(III), and it successfully detects these ions in lake and tap water without pretreatment. The autocatalytic mechanism involves Ag(I) and Fe(III) reduction to Ag nanoparticles and Fe(II), respectively, which further catalyze the reaction, enhancing selectivity and efficiency. The method is cost-effective, simple, and suitable for on-site environmental monitoring.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Shihua Wang,Yiting Qiu,Lichao Yu,Kongqin Lu,Bing Du,Jin Zhang,Hangxin Gong,Aocheng Ren,Min Chen,Hongchen Zhang,Xu-Feng Zang,Xiaoxia Ye,Leyi Cai,Yun-Yun Quan,Zu-Sheng Huang
The precise distribution and subcellular localization of photosensitizers (PSs) play a crucial role in maximizing the utilization of reactive oxygen species (ROS) and enhancing photodynamic therapy (PDT). However, the therapeutic efficacy of PDT is significantly compromised by the hypoxic microenvironment, particularly in malignant tumors. To address these challenges, we designed and synthesized three donor–donor-π-bridge-acceptor (D-D-π-A) type aggregation-induced emission (AIE) PSs: TCM-OTs , TCM-OH , and TCPy-OH . By fine-tuning the acceptor and donor substituents, we successfully modulated organelle-targeting specificity and ROS generation to mitigate hypoxia-related limitations. Among these compounds, TCM-OH emerged as a highly promising PS, exhibiting selective mitochondrial targeting and efficient type-I ROS generation. To further enhance its pharmacological properties, we encapsulated each PS into DSPE-PEG2k to form nanoparticles (NPs). Notably, TCM-OH NPs facilitated the production of superoxide (•O 2 − ) and hydroxyl radicals (•OH) within mitochondria, leading to mitochondrial dysfunction and subsequent cell death via a synergistic ferroptosis-apoptosis pathway under light irradiation. Both in vitro and in vivo experiments demonstrated the potent therapeutic efficacy of this strategy, with minimal toxicity, underscoring its potential for hypoxic cancer treatment. Overall, this study provides a rational design framework for developing potent type-I PSs with multimodal capabilities for biomedical applications.
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