SENSORS AND ACTUATORS B-CHEMICAL
·
2022
·
IF 9.221
Lei Cao,Tongtong Zhu,Minghui Zan,Yulu Liu,Xiaoman Xing,Qing Qian,Qian Mei,Wen-Fei Dong,Li Li
Tea polyphenols (TP), which is accounting for 15–30% of the dry weight of green tea and are widely used in the food industry as antioxidants , preservatives, color preservatives, and flavoring agents . To determine the concentration of TP, a fluorescent method based on nitrogen and chlorine co-doped carbon dots (R-CDs) was investigated. The R-CDs we prepared showed red emission with an absolute quantum yield (QY) of approximately 16.67 ± 0.85%. The limit of detection (LOD) was calculated to be approximately 68 ± 0.94 ng/mL, with an R 2 of 0.999 over the TP range of 1–20 μg/mL. Compared to the ferrous tartrate standard curve method, the concentration of TP in green tea, which was purchased from the market, detected using our method showed an error within 5%, indicating good potential applications in the food industry. Cell imaging experiments suggested that the R-CDs exhibit excellent lysosomal targeting as the Pearson’s correlation coefficient (PCC) in colocalization analysis was found to be 0.91. Further experiments showed that owing to their excitation-independent emission and high QY, the R-CDs could be applied to not only for detecting TP content but also for targeting lysosomes as substitute for commercial dyes.
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高影响因子
FOOD RESEARCH INTERNATIONAL
·
2025
·
IF 8
Xinyao Lin,Chunling Yin,Leqian Hu,Liuchuang Zhao,Mengyao Chen,Xia Hua,Zhimin Liu,Peng Li
Fluorescent sensor arrays are becoming a hot topic in many fields because they can simultaneously detect multiple targets in complex research systems. However, most researches have only collected two-dimensional fluorescence spectral data from fluorescent sensor array interacting with target analytes. In contrast, three-dimensional fluorescence spectra can provide richer information than two-dimensional fluorescence spectra. Based on the hypothesis that collecting three-dimensional fluorescence spectra can obtain more abundant information of green tea samples from different regions, which can improve the accuracy and reliability of origin identification. This study aimed to explore the feasibility of using three-dimensional fluorescent sensor array combined with multi-way pattern recognition methods for the origin discrimination of green tea based on the differences in the contents and types of metal ions in green tea. To investigate this, we first designed a fluorescent sensor array based on amino acid-derived carbon dots and examined its ability to recognize common metal ions in green tea. Excitation-emission matrix spectra of green tea extracts from different geographical origins after interaction with the fluorescent sensor array were collected. Several multi-way pattern recognition methods were used to analyze the three-dimensional fluorescent array data of 100 green tea samples from five origins. The overall classification results of green tea from the five geographical origins were satisfactory, with the best prediction accuracy reaching 96.88%. In comparison, multilinear partial least squares discriminant analysis could make full use of the information of three-dimensional fluorescence data. And its correct identification results for green tea were superior to those of unfold partial least squares discriminant analysis. These results sufficiently demonstrated that the fluorescent sensor array integrated with multi-way pattern recognition, has promising potential for tracing the origin of Chinese green tea.
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PubMed
高影响因子
BIOCHEMICAL PHARMACOLOGY
·
2025
·
IF 5.6
Lei Wang,Yufeng Bai,Dan Ma,Wenxiu Liu,Zhiyu Shi,Chunnan Liu,Meng Zhao,Huiying Wang,Liying Luo,Jinyu Chi
Hypertension is a risk factor for cardiovascular diseases, primarily through its induction of pathological vascular and ventricular remodeling. TEA domain transcription factor 3 (TEAD3) is a transcription factor highly expressed in myocardial tissues. PDZ domain-containing 1 (PDZK1) has been reported to protect blood vessels. This study discovered decreased expression of TEAD3 and PDZK1 in the aortic tissues of spontaneously hypertensive rats (SHRs). TEAD3 overexpression in SHR vascular smooth muscle cells (VSMCs) driven by the SM22α promoter was achieved through adeno-associated virus delivery. TEAD3 overexpression alleviated aortic remodeling by reducing elastic fiber and collagen deposition. This improvement in vascular structure attenuated hypertension. Subsequently, ventricular remodeling was alleviated by reducing periaortic myocardial fibrosis and left ventricular posterior wall thickness. To elucidate the underlying mechanisms, we overexpressed TEAD3 or PDZK1 in SHR-derived VSMCs via adenoviral infection. Both interventions suppressed VSMC proliferation and migration. Crucially, TEAD3 overexpression upregulated PDZK1 expression, and DNA pull-down assays confirmed direct binding of TEAD3 protein to the PDZK1 promoter. PDZK1 knockdown abolished the anti-proliferative and anti-migratory effects of TEAD3. Further analysis suggested that PDZK1 exerted its protective role by inhibiting the phosphoinositide-3-kinase adaptor protein 1-mediated PI3K/Akt pathway. In conclusion, this study reveals that TEAD3-PDZK1 axis attenuates the abnormal proliferation and migration of VSMCs, which ameliorates aortic and left ventricular remodeling in hypertensive conditions. These findings establish a molecular basis for developing targeted therapies against hypertension-induced cardiovascular remodeling.
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高影响因子
FOOD HYDROCOLLOIDS
·
2026
·
IF 13.8
Kai Du,Zhaoxian He,Ziyang Ren,Xuefei Yang,Mingchun Wang,Zhi Zheng
The starch-polyphenol complexes have been extensively studied, but interaction mechanisms between starch and the specific monomer of tea polyphenols (TP) and the modulatory effect on the quality characteristics of rice noodles requires further investigated. In this work, a comparative analysis on the structures and quality characteristics of TP-fortified rice noodles derived three typical indica rice cultivars (Hly 16, Ly 6176, and Zz 83) was conducted, among which Zz 83 was further selected to assess the complexation mechanism between starch and four major TP monomers (EC, EGC, ECG, and EGCG). The results showed that the formation of starch-TP complexes improved the gel properties, in which Zz 83 with TP exhibited the highest final viscosity and setback value. The network structures of rice noodles became loose and cross-sectional pores were larger upon adding TP. Rice noodles prepared by Zz 83 with TP added (Zz 83-TP) exhibited the best quality performance, which showed increased hardness (2638.93 g) and lowest cooking loss (7.19 %). TP significantly inhibited starch hydrolysis rate, while Zz 83-TP showed the strongest anti-digestibility with the hydrolysis index of 45.60 % and eGI value of 64.74. The binding capacity of galloylated catechins (EGCG, ECG) to starch was significantly higher than that of non-galloylated catechins (EGC, EC) with affinity rankings as EGCG > ECG > EGC > EC. EGCG could effectively induce starch the V-type single helical structures with the relative crystallinity of 19.38 %. This study provides a theoretical basis for the development of starch-based food design with low digestibility.
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高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Weiwei Wu,Yanming Tuo,Zhihui Wang,Na Chen,Yuxue Jiang,Chuanjiu Wu,Yongquan Xu,Wen Zeng,Weijiang Sun
Tea flowers and seeds, non-leaf organs of Camellia sinensis , are often discarded, leading to inefficient resource utilization. This study evaluated the potential of tea flowers and seeds by preparing white teas from fresh leaves (WT), flowers (WTF), and seeds (WTS) of Camellia sinensis cv. Fuding Dabaicha. Sensory evaluation, targeted metabolomics, and molecular simulations were used to investigate taste components and their impact on pleasantness. WTF exhibited the highest pleasantness score (6.60), followed by WTS (6.36) and WT (6.10). Four sugars— d -fructose, glucose, D-galactose, and D-xylose—synergistically enhanced pleasantness, with a dose-dependent increase, especially d -fructose. Molecular simulations showed these sugars formed a stable binding network with the CHRM1 receptor (−60.04 kcal/mol), with d -fructose as the key contributor. Alanine scanning identified ARG123 as a critical binding residue. This study provides support for the high-value utilization of tea flowers and seeds and offers insights into enhancing the pleasantness of tea beverages.
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高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2026
·
IF 5.1
Ruohan Xu,Ming Liu,Tallat Munir,Shiyang Bai,Jihong Sun,Haoqian Guo,Zhongchao Sun,Xiaoyan Bai
This study explores the preparation of the Ni-based catalysts supported on clinoptilolite (CP) for dry reforming of methane (DRM) using three methods: impregnation, complex route, and one-pot synthesis. The impact of these strategies on Ni dispersion and catalytic performance was investigated. Triethylamine was utilized as a complexing agent to improve Ni dispersion, prevent catalyst sintering, and reduce carbon deposition. The physicochemical properties were characterized using X-ray diffraction patterns, Fourier transform infrared spectroscopy, Raman spectra, and X-ray photoelectron spectroscopy spectra, N 2 adsorption–desorption isotherms, scanning electron microscopy and transmission electron microscopy images, hydrogen temperature-programmed reduction and thermogravimetric analysis. The results indicate that the CP-TEA/4Ni catalyst prepared via the complex route exhibited a higher Ni content (2.84 wt%) and demonstrated the highest initial activity at 600 °C (44.5% CH 4 conversion, 43.4% CO 2 conversion). Conversely, the (3NiTEA)CP catalyst synthesized via the one-pot method confined Ni particles within the microporous structures of CP, significantly suppressing carbon deposition and Ni particle growth, and thereby ensuring exceptional stability (105 h at 600 °C). The amorphous and graphitic carbon deposition coexisted in the deactivated catalysts, whereas the I D /I G value of the deactivated CP/TEA-3Ni was higher. Furthermore, Grand Canonical Monte Carlo-Molecular Dynamics coupled simulations revealed that surface Ni clusters were conducive to enhancing CH 4 adsorption heat and facilitating CO 2 diffusion, which effectively inhibited carbon deposition. These findings underscore the role of synthetic strategies in designing high-performance Ni-based catalysts for DRM reaction, offering pathways to more cost-effective, stable, and efficient catalysts for industrial methane reforming and carbon emission reduction.
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高影响因子
FOOD AND CHEMICAL TOXICOLOGY
·
2026
·
IF 3.2
Lili Liu,Zhengyao Li,Xinlei Peng,Hongli Zhang,Yuying Yang,Jun Liu,Min Liu
TPs reduced oxidative stress in PFOA-exposed mice. • TPs reduced intestinal permeability and ERK/NF-κB pathway in the ileal tissue. • TPs reduced harmful bacteria and increased beneficial bacteria in PFOA-exposed mice. • TPs as a potential dietary intervention alleviate pollutant-induced enterotoxicity. Perfluorooctanoic acid (PFOA), a persistent environmental contaminant, has been found to induce intestinal damage. Dietary tea polyphenols (TPs) have been reported to alleviate gastrointestinal diseases, however, the underlying mechanism through which TPs alleviate PFOA-induced ileal barrier injury remains unclear. Here, the effects of TPs on oxidative stress, intestinal permeability, extracellular signal-regulated kinase (ERK)/nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway, and gut microbiota in mice were evaluated. The results showed that TPs alleviated oxidative stress by elevating the serum GSH and CAT activities, and reducing MDA levels. Moreover, TPs decreased intestinal permeability by reducing serum DAO and LPS levels, upregulating the expression of claudin-1 and occludin, and inhibiting the phosphorylation of ERK and NF-κB in the ileum. Additionally, 16S rRNA gene sequence analysis revealed that TPs reversed PFOA-induced gut dysbiosis by decreasing harmful bacteria of Desulfovibrio and Ileibacterium , and increasing beneficial bacteria of Lachnospiraceae_NK4A136_grou p and Ligilactobacillus . This study reveals positive effects of TPs as a potential dietary intervention against pollutant-induced enterotoxicity. Download: Download high-res image (250KB) Download: Download full-size image
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高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Jiaying Yang,Danqiu Li,Jiayi Chen,Wenkai Zhang,Zixin Ni,Hongjing Pan,Yuefei Wang,Xiaoli Li,Jihong Zhou
Microclimate shapes sensory, chemical, and microbial changes in Pu-erh raw tea. • Microbial shifts drive chemical evolution during natural tea storage. • Hyperspectral-based machine learning identifies storage years accurately. • Two-dimensional correlation spectroscopy reveals sequential component changes. • Random forest models predict and visualize key bacterial abundances from spectra. This study developed a non-destructive approach for identifying storage years and quality evolution of Pu-erh raw tea by integrating sensory evaluation, chemical analysis, electronic nose/tongue, hyperspectral imaging, and 16S rRNA sequencing. Results revealed that Bacillus and Pantoea shifts drive chemical transformations; notably, Bacillus abundance reached 40.44% in Hangzhou-stored samples after six years, correlating with significant degradation of polyphenols and ester-type catechins. Specific wavelengths at 1633, 1085, and 1250 nm were intrinsically linked to alterations in caffeine, polyphenols, and amino acids, respectively. Among tested models, Random Forest coupled with Standard Normal Variate preprocessing achieved 100% classification accuracy in the near-infrared band. Furthermore, Random Forest regression successfully visualized bacterial succession trends based on spectral data. Overall, this integrated strategy provides a rapid, non-invasive methodological framework for tea quality control, offering a valuable reference for the future expansion and validation of diverse tea aging processes.
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高影响因子
FOOD RESEARCH INTERNATIONAL
·
2026
·
IF 8.8
Taisong Fang,Songbai Liu
Curcumin (Cur) and anthocyanin (Ant) are typical plant-derived bioactives with promising biological benefits, but poor stability and bioavailability limit their applications. To address these challenges, we engineered a targeted co-delivery platform by systematically comparing two representative, probiotic-derived extracellular vesicle carriers: outer membrane vesicles (OMVs) from Escherichia coli Nissle 1917 and extracellular vesicles (EVs) from Lactobacillus plantarum . Encapsulation efficiency (EE) of Cur was 41.6% for OMVs and 35.9% for EVs, whereas EE of Ant was 25.4% and 24.6%, respectively. Both vesicle types were further synergistically functionalized with specifically acylated epigallocatechin palmitate (EGCp) and octenyl succinic anhydride-grafted hyaluronic acid (OSA-HA). The incorporation efficiency of EGCp was 27.2% for OMVs and 37.3% for EVs. The self-assembly process yielded composite nanovesicles with a reduced particle size (OMVs: from 165.6 nm to 143.2 nm; EVs: from 156.8 nm to 120.8 nm) and a more negatively charged surface (from −20.8 mV to −37.5 mV for OMVs; from −18.3 mV to −35.3 mV for EVs) compared to their native counterparts, indicating improved colloidal properties. In addition, both engineered nanovesicles effectively protected the encapsulated bioactives, significantly enhancing their stability against simulated gastrointestinal digestion and oxidative stress. For example, the retention of Cur under oxidative conditions increased from 24.2% in unmodified OMVs to 69.1% in the optimized formulation within 2 h. Cellular uptake assays confirmed the OSA-HA coating achieved targeted delivery to inflammatory macrophages, with OSA-HA-modified OMVs exhibiting higher cellular internalization (75.4% at 12 h) than similarly modified EVs (61.8% at 12 h). While both types of functionalized nanovesicles enhanced intracellular antioxidant activity to a similar extent, the OMV-based system demonstrated superior suppression of pro-inflammatory mediators (NO, TNF-α, and IL-6) in mitigating lipopolysaccharide (LPS)-induced cell damage. This comparative study establishes a biocompatible probiotic-based colloidal platform, demonstrating the potential of two selected engineered probiotic vesicles and functionalized polysaccharides for the encapsulation and targeted cellular delivery of sensitive bioactive compounds.
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高影响因子
RSC Advances
·
2026
·Vol. 16
·期 30
·27707-27717
·
IF 6.1
Yulu Liu,Jiamin Li,Yizhou Xiao,Yuchi Chen,Yunkai Zhou,Fangmei Zhou,Bingqi Zhu,Wenxiao Jiang,Xing Chen,Guangming Li
The application of biomass-derived carbon dots (CDs) in smart food packaging is often limited by their low photoluminescence quantum yield. Here, we report a one-pot hydrothermal synthesis of high-performance CDs from black tea waste using citric acid as a multifunctional modulator. FTIR, XPS, zeta potential, and TEM measurements collectively reveal that citric acid enhances photoluminescence primarily through surface passivation, accompanied by the formation of smaller and more uniform carbon cores with a narrower size distribution. This synergistic modulation, dominated by surface passivation, leads to a 25.5-fold quantum yield enhancement from 0.4% to 10.2%, a narrowed emission spectrum with full width at half maximum reduced from 105.59 nm to 64.95 nm, a prolonged fluorescence lifetime from 2.86 ns to 6.93 ns, and improved photostability. Leveraging these optimized properties, the as-prepared CDs are applied in two functional systems for food applications. As a fluorescent ink, they enable covert anti-counterfeiting patterns that are invisible under ambient light but emit bright blue fluorescence under UV excitation. Additionally, a nanocomposite coating incorporating these CDs significantly extends the shelf life of strawberries at room temperature, as evidenced by reduced weight loss, maintained firmness, and preserved soluble solids content over a six-day storage period. This work presents a citric acid-mediated strategy for upcycling agricultural waste into value-added carbon nanomaterials, advancing sustainable and intelligent food packaging technologies.
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PubMed
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Chen Chen,Zijun Li,Haiyan Yu,Lianbo Su,Huaixiang Tian,Haibin Yuan
Fresh walnuts are highly perishable due to high moisture and unsaturated lipid contents. A multifunctional coating was developed by grafting glycerol onto oxidized bacterial cellulose to form a stable nanonetwork and incorporating tea polyphenols. Structural analyses revealed a compact network with improved crystallinity and barrier integrity, supporting sustained release of tea polyphenols. The coating exhibited strong antioxidant activity (72% scavenging) and broad-spectrum antibacterial efficacy (inhibition rates up to 97.8%). Cytocompatibility assays using human gastric epithelial cells confirmed excellent biocompatibility. When applied to fresh walnuts, the coating reduced moisture loss (maintaining a moisture content of 23.4%), delayed lipid oxidation (suppressing acid value to 2.3 mg KOH·g −1 ), and preserved total phenolic content (3.52 mg/g) after 60 days. Furthermore, it effectively inhibited microbial growth, maintaining the total viable count at 3.8 log CFU/g, significantly below the safety threshold. These results demonstrate a green, effective strategy for sustainable preservation of perishable nuts.
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高影响因子
ACS Applied Polymer Materials
·
2026
·
IF 5.2
Nie Zixuan,Xu Yiting,Yang Xin,Yu Jiahui,Ye Dezhan,Chen Guoqi,Zhan Yanhu,Jiang Xiancai
Solar-driven interface evaporation technology offers
a green and
sustainable solution to alleviate the global freshwater crisis. However,
traditional hydrogel evaporators generally have problems such as small
pore diameters, limited water transmission, complex preparation processes,
and the high cost of photothermal materials. In this study, a green
and low-cost soybean protein isolate (SPI)/poly(vinyl alcohol) (PVA)/tea
leaf residue (SPT) biomass porous sponge solar evaporator was developed
based on the salting-out effect-induced phase separation strategy
and the tea polyphenol (TP)-Fe 3+ complex blackening strategy.
The whole preparation process of SPT has low energy consumption and
high efficiency. The mechanical properties, microscopic pore structure,
hydrophilicity, and photothermal behavior of the SPT sponge were measured.
The results show that SPT has excellent light absorption performance,
achieving an absorption rate of 92.6% in full-spectrum sunlight. DSC
results showed that SPT has a low evaporation enthalpy of 1478 J/g.
SPT achieves a pure water evaporation rate of 3.30 kg m –2 h –1 and an evaporation efficiency of 94.88% under
1 sun. Meanwhile, SPT also demonstrated outstanding salt resistance
and stability and exhibited excellent purification performance for
real seawater. This work has developed an environmentally friendly
and cost-effective strategy to fabricate an efficient biomass material-based
solar evaporator, which can be used for long-term sustainable seawater
desalination.
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高影响因子
危险品化学品经营许可证（带存储）