TALANTA
·
2024
·
IF 5.6
Konghao Han,Zilong Yan,Zhuang Ding,Pengfei Zhou,Cheng Ye,Ling Qin,Zhiyong Bao,Maofeng Zhang,Wei Zhang
The proliferation of micro/nanoplastics (MNPs) has emerged as a pivotal environmental issue, largely due to their potential for human exposure. Consequently, the development of sensitive and efficient detection methodologies is paramount for elucidating their environmental footprint. Here, we report a novel three-dimensional (3D) surface-enhanced Raman scattering (SERS) sensor, which integrate Ti 3 C 2 T x /TiO 2 /W 18 O 49 semiconductor heterostructure, for the rapid and sensitive detection of MNPs in environmental matrices. The sensor's unique layered architecture and efficient charge transfer mechanism endow it with high sensitivity. It has demonstrated remarkable detection capabilities, achieving a sensitivity of 10 −8 M for Rhodamine 6G (R6G), equating to an enhancement factor (EF) of 2.33 × 10 6 . This level of sensitivity allows for the detection of polystyrene (PS) microplastics at concentration as low as 25 μg/mL, with a relative standard deviation (RSD) of 12.58 %, signifying superior reproducibility. Moreover, the sensor's fingerprinting capabilities enable the identification of a variety of MNPs, including polyethylene (PE) and polyethylene terephthalate (PET), thus facilitating the analysis of complex MNPs mixtures. The sensor's applicability to real-world samples was confirmed through the quantitative detection of PS microplastics in rainwater, soil, and industrial wastewater, with a detection limit of 25 μg/mL and exhibiting good linearity. It is concluded that the 3D SERS sensor is a promising tool for the rapid and precise detection of MNPs across diverse environmental matrices. The advent of this technology marks a significant leap forward in environmental analysis, providing a robust method for the monitoring of MNPs pollution.
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JOURNAL OF HAZARDOUS MATERIALS
·
2024
·
IF 12.2
Xingqi Huang,Haibo Wang,Lingce Kong,Zihao Chen,Jingjing Zhang,Yanjun Zuo,Wenming Chen
The microwave-assisted hydrothermal method has facilitated the straightforward and efficient production of nanoscale Ce x Zr 1−x O 2 /Ti 3 C 2 T x composites. This technique has greatly shortened the synthesis time several hours required by conventional hydrothermal method to merely 10 min. Due to the unique mechanism of microwave-hydrothermal synthesis, composites with excellent crystallinity, uniform particle size, and superior degradation capabilities can be obtained without calcination. Our investigation systematically explores the influence of various factors including mineralizer concentration, dispersant types, synthesis duration, cerium-to-zirconium ratio, as well as MXene content on the material properties. Optimal degradation of 2-chloroethyl ethyl sulfide (2-CEES), sulfur mustard simulants, is achieved using PEG1000 as the dispersant, a cerium-to-zirconium ratio of 1:2, along with 15 mL of MXene, resulting in a remarkably short half-life of only 6.5 min. Furthermore, it is confirmed that the incorporation of cerium atoms into ZrO 2 lattice, forming a solid solution that is deposited onto the interlayer and surface of Ti 3 C 2 T x nanosheets, with the composite particles measuring approximately 5.01 nm. The reduced size and increased specific surface area, coupled with the synergistic effects of oxygen vacancies and acid-base sites, ultimately contribute to the hydrolysis and elimination reactions occurring on 2-CEES. This research offers fresh perspectives on the development of novel materials for the degradation of chemical warfare agents.
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MICROCHEMICAL JOURNAL
·
2021
·
IF 4.821
Yunfei Wang,Wenjie Sun,Yixiao Li,Xuming Zhuang,Chunyuan Tian,Feng Luan,Xiuli Fu
Human immunodeficiency virus (HIV) is still a significant global health concern. Hence, developing a rapid and sensitive method for the detection of HIV is important in early detection. In this paper, we focus on the preparation of a sensitive electrochemical luminescence (ECL) biosensor that uses Ti 3 C 2 T x modified ZIF-8 as an ECL emitter to detect HIV-1 protein. This ECL biosensor used 0.05 M K 2 S 2 O 8 as the co-reactant and conductive carbon black combined with magnetic nanoparticles as the quenching agent. Under the optimized experimental conditions, the relationship was linear in the range from 1 fM to 1 nM (R 2 = 0.993) and the detection limit was 0.3 fM (S/N = 3). Finally, we used the constructed Ti 3 C 2 T x /ZIF-8 nanocomposites to detect HIV-1 in real serum samples and obtained great recoveries. The results demonstrated that this biosensor, which not only exhibited improved electrical conductivity but also demonstrated an excellent ECL response, could be a promising candidate for HIV-1 detection.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2020
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IF 7.1
Fenghe Duan,Chuanpan Guo,Mengyao Hu,Yingpan Song,Minghua Wang,Linghao He,Zhihong Zhang,Riccardo Pettinari,Liming Zhou
A promising nanocarrier of the complementary DNA (cDNA) toward miRNA-155 was synthesized on the basis of the nanohybrid type of Ti 3 C 2 T x MXene nanosheets decorated using iron phthalocyanine quantum dots (FePc QDs) (denoted as Ti 3 C 2 T x @FePcQDs) to construct a novel ultrasensitive impedimetric aptasensing system for microRNA-155 (miRNA-155). Owing to π–π* stacking interaction between Ti 3 C 2 T x nanosheets and FePc QDs, the homogeneous nanostructure of the Ti 3 C 2 T x @FePcQD nanohybrid that comprises mixed-valence states (Ti 2+ /Ti 3+ and Fe 2+ /Fe 3+ ), multicomponent (Ti-O and Ti-C), and various N-related groups was achieved. The constructed Ti 3 C 2 T x @FePcQDs-based aptasensor displayed an ultrahigh sensitivity for detecting miRNA-155 with a low detection limit of 4.3 aM (S/N = 3) within the miRNA-155 concentration ranging from 0.01 fM to 10 pM. Compared with the individual component-based aptasensors and other reported miRNA-155 aptasensors, the proposed impedimetric aptasensing system exhibited substantial merits of a feasible preparation process, non-use of labels or electrochemical indicators, fast response time, and comprehensive sensing performances for detecting miRNA-155. This strategy for determining miRNAs can extensively be applied as the platform for anchoring other kinds of aptamers in detecting diverse targets, thus indicating its great potential application for the early diagnosis of cancer biomarkers.
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ACS Applied Nano Materials
·
2025
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IF 5.5
Feng Ding,Xiong Shuai,Shuping Peng,Cijun Shuai
Nitric oxide (NO) is a small, gaseous, and highly diffusible signaling molecule that plays a pivotal role in numerous physiological and pathological processes. Its therapeutic application, however, presents two major challenges: the cytotoxicity arising from high concentrations of NO that generate reactive nitrogen species and the difficulty in controlling its release due to an extremely short half-life (seconds to minutes). Herein, a GSNO-loaded mesoporous silica/Ti3C2Tx nanosheet composite was constructed by combining mesoporous SiO2 loaded with the NO donor GSNO and Ti3C2Tx nanosheet. Then, silica/Ti3C2Tx nanosheet composites were introduced into poly-l-lactide to fabricate a magnetic field-responsive electrostimulation/NO codelivery scaffold. This system achieves spatiotemporally coupled wireless electrical stimulation and NO delivery, significantly enhancing the regenerative capacity of damaged nerves. The results demonstrated that the scaffold exhibited synergistic wireless electrostimulation/NO codelivery. Under a rotating magnetic field, the current intensity was positively correlated to the magnetic field speed. Meanwhile, the stent achieves precise spatiotemporal control of the NO release. The mechanism of NO release is induced by the pulse effect of the rotating magnetic field, which acts on the S-NO chemical bond of GSNO. This process significantly promotes the neural differentiation and proliferation of mesenchymal stem cells. Through PCR and immunofluorescence analysis, the expression of MAP2 and Tuj was upregulated, while Nestin expression was downregulated. Summarily, the scaffold with electrical stimulation and NO release can further enhance nerve differentiation.
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Biosensors-Basel
·
2021
·Vol. 11
·期 11
·462
·
IF 5.519
Yangguang Zhu,Qichen Tian,Xiufen Li,Lidong Wu,Aimin Yu,Guosong Lai,Li Fu,Qiuping Wei,Dan Dai,Nan Jiang,He Li,Chen Ye,Cheng-Te Lin
Considering the vital physiological functions of dopamine (DA) and uric acid (UA) and their coexistence in the biological matrix, the development of biosensing techniques for their simultaneous and sensitive detection is highly desirable for diagnostic and analytical applications. Therefore, Ti3C2Tx/rGO heterostructure with a double-deck layer was fabricated through electrochemical reduction. The rGO was modified on a porous Ti3C2Txelectrode as the biosensor for the detection of DA and UA simultaneously. Debye length was regulated by the alteration of rGO mass on the surface of the Ti3C2Txelectrode. Debye length decreased with respect to the rGO electrode modified with further rGO mass, indicating that fewer DA molecules were capable of surpassing the equilibrium double layer and reaching the surface of rGO to achieve the voltammetric response of DA. Thus, the proposed Ti3C2Tx/rGO sensor presented an excellent performance in detecting DA and UA with a wide linear range of 0.1–100 μM and 1–1000 μM and a low detection limit of 9.5 nM and 0.3 μM, respectively. Additionally, the proposed Ti3C2Tx/rGO electrode displayed good repeatability, selectivity, and proved to be available for real sample analysis.
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TRIBOLOGY INTERNATIONAL
·
2024
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IF 6.1
Han Yan,Leifeng Shi,Dezhi Zeng,Lin Zhang
Friction damage is always a major threat to the wide application of smart anticorrosion coatings. Here, the tribological properties of a smart Ti 3 C 2 T x -based epoxy coating (MLT@EP) is adjusted by the reasonable collocation of mesoporous silica nanocapsules loading onto Ti 3 C 2 T x -based plane (MLT). MLT@EP not only maintains good smart anticorrosion, but also has remarkable anti-friction and anti-wear properties. Its friction coefficient exhibits a low and steady trend, and the wear rate arrived at 1.14 × 10 −5 mm 3 /N·m, which is decreased by 58.3 ∼ 93.3 % compared to control groups. The excellent tribological properties are mainly attributed to the synergistic effect of MXene-based lubrication film, high resistance to plastic deformation, and strong internal interaction.
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CHEMICAL ENGINEERING SCIENCE
·
2026
·
IF 5.1
Siraj Ullah,Waqas Ahmed,Shuozhen Hu,Xinsheng Zhang
Electrochemical water splitting is a potential method for sustainable hydrogen production. Achieving efficient and durable bifunctional electrocatalysts for alkaline water splitting remains challenging due to sluggish OER/HER kinetics and a reliance on noble metals. Here, we introduce MX-CoFe/EMN, a binder-free hybrid electrocatalyst fabricated by sequential electrodeposition of Ti 3 C 2 T x MXene integrated CoFe layered double hydroxide (LDH) nanosheets onto nickel foam. Combining CoFe LDH with MXene, which serves as both conductive scaffold and active component, yields beneficial interfacial electronic interactions, enhanced charge transfer, and a high density of active sites. In 1.0 M KOH, MX-CoFe/EMN shows low overpotentials of 260 mV (OER) and 279 mV (HER) at ±100 mA cm −2 , small Tafel slopes 39 mV dec −1 (OER), 68 mV dec −1 (HER), and excellent durability of over 80 h at ±500 mA cm −2 . These findings demonstrate a scalable electrodepositin-based approach for developing highly active and durable non-noble-metal electrocatalysts for sustainable hydrogen generation.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.6
Yi Zhao,Yidong Hu,Yingchun Guo,Kai Ge,Binyuan Liu,Yongfang Yang
In-situ construction of a Ti 3 C 2 T x @MOF heterojunction with the heterovalent Cu 2+ /Cu + sites. • Exceptional CO production rate of 141.6 μmol·g −1 ·h −1 via synergistic photothermal and pseudo-greenhouse effects. • The proper ratio of Cu 2+ /Cu + endows the 2D Ti 3 C 2 T x @MOF-CuII/CuI heterojunctions with good cyclic catalysis. • DFT reveals Cu + sites facilitate CO 2 adsorption and reduce energy barrier in the rate-determining step during CO 2 reduction. The direct photocatalytic reduction of CO 2 into valuable chemicals and fuels using non-precious metal catalysts offers a promising strategy to address the energy crisis and mitigate carbon emissions. However, designing highly efficient photocatalysts remains a significant challenge. In this work, we fabricate two-dimensional (2D) Ti 3 C 2 T x @MOF-CuII/CuI heterojunctions that exhibit a CO evolution rate of 141.6 μmol·g −1 ·h −1 , which is approximately 21.8 and 13.0 times that of pristine 2D Ti 3 C 2 T x and 2D MOF Cu, respectively. Furthermore, the synergistic combination of the photothermal effect of Ti 3 C 2 T x and the nanoscale pseudo-greenhouse effect of the MOF-Cu layers further enhances the photocatalytic activity of the heterojunction, surpassing that of previously reported MXene-based materials. Characterization and computational studies reveal that the high intrinsic reducibility of Ti 3 C 2 T x drives the reduction of about 53% of Cu 2+ to Cu + in the resulting 2D Ti 3 C 2 T x @MOF-CuII/CuI heterojunctions. The abundant Cu 2+ /Cu + sites are uniformly distributed throughout the heterostructure, leading to a reduced energy barrier for key reaction intermediates. In addition, the proper ratio of Cu 2+ /Cu + endow the 2D Ti 3 C 2 T x @MOF-CuII/CuI heterojunctions with good cyclic catalysis, thus realizing the continuous photocatalytic reduction. This study provides deep insights into the construction of heterovalent Cu 2+ /Cu + heterojunctions based on MOFs and MXene, enabling the highly efficient collaborative photothermal and photocatalytic CO 2 reduction. Schematic illustration of the 2D Ti 3 C 2 T x @MOF-CuII/CuI heterojunction for synergistic photothermal and photocatalytic CO 2 reduction. Download: Download high-res image (104KB) Download: Download full-size image
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2023
·
IF 5.2
Yuncong Yang,Wenmin Song,Balaji Murugesan,Xiuwen Cheng,Mingming Jiang,Zhuo Chen,Beifa Yan,Yurong Cai
Flexible strain sensors have attracted the attention of researchers due to their wide range of applications in wearable electronic skin and healthcare monitoring. The fabrication of flexible strain sensors with high strength , good linear sensitivity, stability and comfort is still challenging. Here, an anisotropic silk fibroin (SF) based hydrogel is fabricated through an oriented freezing method and a low-temperature concentration is to follow. This approach combines HA with SF to increase the hydrogel's water-holding capacity, and Ti 3 C 2 T x MXene is doped as a conductive-sensitive component. Benefitting from the synergy of its well-designed components and the oriented internal crosslinking network structure, the hydrogel has a wide working range and a stable resistance response under 0∼80% compression strain. Especially the oriented hydrogel has ultra-high compression resilience (∼ 99%) in the orientation direction, and it is stable and durable for up to 10,000 cycles under 50% compression self-rebound. Flexible sensors made of conductive hydrogel were attached to the human body or combined with out-of-body clothing to detect human movement. Based on these findings, the prepared conductive hydrogel could be used as a wearable strain sensor material.
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Nano Today
·
2023
·
IF 17.4
Xianyu Zhu,Wenqi Zhang,Huandong Xiang,Qingchao Chang,Ruixue Liu,Yilong Wan,Ruiting Zhang,Feng Zhao,Yongxing She,Hui Yuan,Jigang Yang,Qiqiang Li,Shanshan Wang,Liang Yan
Synergistic radiosensitization of cancer cells by metal-based nanomaterials and natural products is a forward-looking alternative for radiotherapy enhancement while inhibiting tumor metastasis. This work explores a phase change material (PCM)-gated Ti 3 C 2 T x nanosheet as a photothermal-responsive drug delivery system for loading natural trans -resveratrol (RSV), aiming at such synergistic radiosensitization in a controlled manner. This system can improve the biodispersity of RSV in the physiological solutions and inhibit the radiation-enhanced enzymatic activity of Ti 3 C 2 T x nanosheets to a large extent. Upon 808 nm near infrared light illimitation, Ti 3 C 2 T x -mediated photothermal heating makes the loaded PCM to be melted, resulting in the controlled release of RSV and simultaneous recovery of radiation-enhanced enzymatic activity of Ti 3 C 2 T x nanosheets. By further irradiating with X-ray, Ti 3 C 2 T x nanosheets is responsible for enhanced catalytic decomposition of H 2 O 2 to highly toxic hydroxyl radical as well as the consumption of intracellular glutathione . Both in vitro and in vivo studies demonstrate that those excess radical oxygen species can synergize with the released RSV to induce cancer cell death by apoptosis/ferroptosis hybrid pathway, fully inhibiting growth and metastasis of orthotopic breast cancer. These results reveal that the combination of PCM-gated Ti 3 C 2 T x nanosheets with RSV is capable of fabricating the photothermal-responsive theranostic systems and aiding the confinement of synergistic radiosensitization exclusively in the cancer cells for radiotherapy enhancement against tumor metastasis.
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ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Haoqiang Wang,Yu Wang,Yani Liu,Shuming Dou,Wei Gan,Qunhui Yuan
To alleviate kinetics imbalance and capacity insufficiency simultaneously, a novel hierarchical structure (SnCu2Se4/d-Ti3C2Tx/NPC) composed of delaminated Ti3C2Tx, SnCu2Se4 nanoparticles, and N-doped porous carbon layers is designed as a battery-type anode for lithium/sodium ion hybrid capacitor (LIC/SIC). The combination of SnCu2Se4 nanoparticles with high specific capacity, d-Ti3C2Tx with accelerated ion diffusion path, and NPC with enhanced electronic conductivity makes the SnCu2Se4/d-Ti3C2Tx/NPC composite possess excellent cycling stabilities in half-cell lithium-ion and sodium-ion batteries (LIB and SIB), with capacities of 114 mAh g–1 after 6000 cycles at 10 A g–1 for LIB and 296 mAh g–1 after 900 cycles at 1.0 A g–1 for SIB. The rate performance is also outstanding, with recovered capacity of 738 mAh g–1 at 0.1 A g–1 after cycles at current densities up to 50 A g–1 for LIB. Subsequently, LIC and SIC based on the SnCu2Se4/d-Ti3C2Tx/NPC anode and activated carbon cathode exhibit high energy densities of 147.9 and 158.6 Wh kg–1 at a power density of 100 W kg–1, respectively. They also possess distinctive long lifespans with capacity retentions of 78 and 81% after 10,000 cycles at 1.0 A g–1, respectively, demonstrating the feasibility of SnCu2Se4/d-Ti3C2Tx/NPC toward energy devices requiring high energy density, power density, and long-term stability.
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