MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Guoni Huang,Jiezhen Pan,Junfang Zhu,Ye Zhang,Xiaohe Zhang,Shihua Luo
In this study, we introduce an ultrasensitive electrochemical RNA biosensor based on hyperbranched primer exchange reaction (HPER) cascade amplification and Au@Pt@UiO-66-NH 2 nanozymes. This strategy employs catalytic hairpin assembly (CHA) for precise target RNA recognition, which trigger the immobilization of HPER products onto the electrode surface, thereby providing binding sites for nanozymes. Then, the sDNA@Au@Pt@UiO-66-NH 2 signal probes (sDAPU probes) attach to the HPER scaffolds through base-pairing interactions, facilitating signal amplification. The nanozymes catalyze the decomposition of hydrogen peroxide into H 2 O and O 2 , producing a significantly amplified electrochemical signal. By combining CHA-HPER cascade amplification with the catalytic activity of sDAPU probes, the established biosensor achieves remarkable sensitivity, with a detection limit as low as 14.68 aM, and high specificity that enables the differentiation of non-target pathogen RNA. Furthermore, the biosensor also demonstrates excellent recovery rates in serum samples. Therefore, this electrochemical strategy shows great potential as a diagnostic tool for ultrasensitive Mycobacterium tuberculosis detection.
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NEW JOURNAL OF CHEMISTRY
·
2026
·
IF 2.6
Mengjia Sheng,Xiang Zhang,Zhen Song,Hongye Cheng,Zhiwen Qi
The rapid development of dye industry has led to a significant amount of wastewater discharged. As a widely-used dye, toxic and non-degradable methylene blue is becoming a serious threat to our ecosystem. Thus, wastewater containing methylene blue must be treated properly. Considering the strengths of ionic liquid (IL) and metal organic framework (MOF) in molecular separation, a convenient solution strategy is proposed in this work for designing and preparing IL@MOF composite adsorbent in order to efficiently remove methylene blue from water. As a kind of water-stable MOFs, UiO-66 was synthesized by a one-pot method under very mild conditions using deep eutectic solvent (DES) as reaction media instead of conventional organic solvents. The easily obtained UiO-66-DES has superior MB adsorption kinetics but limited adsorption capacity. To mitigate this weakness, a computational and systematic IL screening framework is developed. [EtOHMIM][PF6] is eventually selected from 3569 candidates and incorporated into the UiO-66-DES. The resulted IL@MOF composite maintains the fast MB adsorption while importantly increasing the adsorption capacity from 45.85 mg/g to 227.57 mg/g. Given 10 mg/L MB solution, the removal rate is improved from 34% to 91% in 5 minutes. Meanwhile, the adsorption capacity is almost unchanged after 5 regeneration cycles, which offers great potentials for practical applications. Finally, the detailed mechanism analysis reveals that the loaded IL introduces new adsorption sites with stronger interactions with MB. These results show that the [EtOHMIM][PF6]@UiO-66-DES composite resulted from DES-assisted MOF synthesis and IL-based post-synthesis is a promising material for efficient MB wastewater treatment.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.7
Zeyun Yang,Hao Guo,Yanrui Hao,Yu Yan,Wenting Niu,Jianpeng Ma,Ruixue Yan,Wu Yang
Although caffeic acid (CA) has important physiological effects, such as antioxidant and antibacterial properties, high concentrations of CA can increase the risk of cancer. Therefore, it is very necessary to establish a simple and sensitive detection method for it. Herein, a novel CA electrochemical sensing interface was constructed by in-situ growing NH 2 -UiO-66, a zirconium-based metal-organic framework (MOF), on semiconductor cupric bismuthate CuBi 2 O 4 (CBO) and further loading acidified multi-walled carbon nanotubes (MWCNTs). The obtained nanocomposite fully leverages the respective advantage of each component, including the excellent electrocatalytic activity of CBO, the selective adsorption ability of MOF, and the high conductivity and signal amplification effect of MWCNTs. Particularly, the acid-functionalized MWCNTs possess sufficient surface electroactive groups (sp 2 -C-OH), which can generate a stable electrochemical response through the reversible transformation between hydroxyl and quinone groups, thereby providing an important guarantee for constructing a self-referencing ratiometric electrochemical sensor. The electrochemical sensor was prepared by modifying the composite CBO@NH 2 -UiO-66/MWCNTs on glassy carbon electrode (GCE) to realize CA detection in wide range of 0.2–150 μM with a low detection limit (LOD = 0.052 μM) and excellent reproducibility, stability and selectivity. The analysis of actual beverages including red wine, green tea and coffee also achieved satisfactory recovery results and precision.
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PubMed
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Reaction Kinetics Mechanisms and Catalysis
·
2026
·
IF 2.1
Wang Jiahao,Liu Feng,Xie Lei,Yang Hailiang,Ma Sanjian,Lin Zixia,Liu Xin,Wang Suqin
Refractory wastewater treatment via Fenton reactions is hindered by iron sludge. Herein, fluorinated UiO-66(Zr)-F4 was employed as a hydrogen-storage carrier to confine Pd⁰ catalytic centers, and an [H]-mediated (H 2 -precursored) Fenton-like system was constructed for carbamazepine degradation under ambient conditions. With 25 μM Fe 2 + and 60 mL min⁻ 1 H 2 flow, 53% carbamazepine removal was achieved in 1 h via ⋅OH/ 1 O 2 oxidation, and > 59% efficiency was retained over six 3-h cycles. However, [H]-driven hydrogen spillover reduced C-F bonds, causing a 92.3% drop in specific surface area that compromised long-term stability. It was concluded that fluorination is suboptimal; modulating the carrier’s hydrophobicity via electron-donating groups (instead of fluorination) is critical for stable Zr-MOF-based catalysts in [H]-assisted advanced oxidation, offering alternative perspectives for process optimization. Graphical abstract
The alternative text for this image may have been generated using AI.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2022
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IF 9.136
Jiacong Wu,Juan Han,Yanli Mao,Lei Wang,Yi Wang,Yuanyuan Li,Yun Wang
A metal–organic frameworks (MOFs) with adjustable mesopores was prepared through bionic mineralization using protein as template in this paper. By regulating the content of bovine serum, pore structures of different sizes (6.46, 7.55, 10.80 nm) were obtained, used for the immobilization of enzymes (HRP, laccase and cellulase). It was found that the UIO-66 with a pore size of 6.46 nm exhibited the highest loading capacities for the investigated three enzymes. Under optimized conditions for immobilization, the maximum loading capacity of HRP, laccase and cellulase was 205.7, 214.2 and 203.9 mg g −1 , respectively. It should be noted that the stabilities of the three immobilized HRP@UIO-66, laccase@UIO-66 and cellulase@UIO-66 were significantly improved due to the favorable fitting between the pore size of the carrier material and the enzyme molecular size. In particular, the substrate affinity of the immobilized HRP@UIO-66 (0.120 g L −1 ) is similar to that of free HRP (0.122 g L −1 ). It is mainly due to that the appropriate porous structure of the carrier could avoid the obstruction of the substrate mass transfer channel after the adsorption of enzyme molecules. Moreover, the porous structure has a certain enrichment effect on the substrate, which promotes the catalytic efficiency of immobilized enzymes.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2023
·
IF 5.2
Yan Fan,Xueqin Sun,Wenyuan Zhang,Jiacheng Liu
A novel fluorescent sensor material of Eu 3+ @ Citric acid-functionalized UiO-66 (denoted as Eu 3+ @UiO-66-CA) was prepared successfully via a two-step post synthetic modification towards UiO-66. The as-obtained Eu 3+ @UiO-66-CA presented the characteristic emission of Eu 3+ ions (λ ex = 270 nm), which could be used for rapidly detecting Fe 3+ and Cr 2 O 7 2- ions by luminescence quenching in aqueous solution. The detection process for Fe 3+ ion (detection limit, 18.1 μ M) and Cr 2 O 7 2- ion (detection limit, 8.5 μ M) exhibited the high selectivity and excellent anti-interference ability. Systematic investigations were employed to make clear the mechanism of fluorescence quenching after adding Fe 3+ and Cr 2 O 7 2- ions. Moreover, the Eu 3+ @UiO-66-CA was also used for the determination of Fe 3+ and Cr 2 O 7 2- ions in the Yellow River and tap water.
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APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Chunwen Chang,Qiang Xue,Rong Wang,Zeyu Liu,Yao Liu,Lin He,Fei Liu,Haijiao Xie
Development of an efficient monitoring technology for rapid detection of toxic Pb(Ⅱ) ion in water environments is extremely important. Here, a novel and highly sensitive sensor was prepared using one-step calcination technique, based on Bi 2 O 3 nanoparticles and carbonized metal–organic framework (MOF) nanocomposite. Scanning electron microscopy, transmission electron microscopy, contact angle and X-ray photoelectron spectroscopy characterization methods were used to analyze the morphology and structure of the prepared materials. Based on the electrical double-layer capacitance theory and Raman spectroscopy, changes to the active sites of different modified materials were investigated. Besides, differential charge densities and adsorption energies of the different modified materials in Zr-O clusters were calculated using density functional theory (DFT). A Bi 2 O 3 and carbonized UIO-66-NH 2 (Bi 2 O 3 /C-UIO-66-NH 2 ) -modified glassy carbon electrode was used to detect Pb(Ⅱ) by differential pulse anodic stripping voltammetry. Under optimal experimental parameters, the developed electrochemical sensor has a wide linear range (2–130 μg/L) and a low detection limit (0.05 μg/L). Meanwhile, the sensor has excellent stability, repeatability, and anti-interference properties and has been successfully applied to detect Pb(Ⅱ) in actual water samples. The results of this paper show that our developed sensor an efficient and rapid sensor technology for monitoring lead in water environment.
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Energy Technology
·
2023
·Vol. 11
·期 4
·2201438
·
IF 3.8
Qi Zhang,Sijia Wang,Ye Liu,Mengting Wang,Rentian Chen,Zongyuan Zhu,Xiangyun Qiu,Shoudong Xu,Tao Wei
Benefiting from employing solid composite electrolytes (SCEs), all-solid-state lithium-ion batteries (ASSLBs) are recognized to occupy with high energy density and safety. Herein, a polymer-based SCE membrane (SCE-66@67) with core–shell structured metal–organic frameworks (MOFs) (UiO-66-NH 2 @67) as the fillers is presented. The SCE has combined the advantages of the two kinds of MOFs and shows a satisfying ionic conductivity (2.09 × 10 −4 S cm −1 at 60 °C) and a wide electrochemical stability window of ≈5.0 V. The full cell (Li/SCE-66@67/LiFePO 4 ) also maintains a high capacity of 120.9 mAh g −1 at 3 C. This research might help to promote the development of future SCEs for ASSLBs.
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FOOD CHEMISTRY
·
2023
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IF 8.8
Xiaohai Yan,Yahong Yuan,Tianli Yue
Patulin (PAT) is a potentially harmful mycotoxin to human health and is known to contaminate apple juice. In this work, we developed a ratiometric fluorescence aptasensor using tetrakis(4-carboxyphenyl)porphyrin (H 2 TCPP)-treated octahedral UiO-66-NH 2 (defined as UiO-66-TCPP) to detect PAT. This 2-aminoterephthalic acid and H 2 TCPP functionalized metal-organic framework showed multiple adsorption effects (hydrogen bonding and π–π stacking) on the aptamer (Apt) and served as a quenching material. When the target PAT bound specifically to the Apt, the fluorescence of the 6-carboxyfluorescein-labeled Apt would recover, and the fluorescence of the H 2 TCPP ligand remained unchanged. This ratiometric fluorescence property improved the accuracy of PAT detection. Moreover, the introduction of the H 2 TCPP ligand enhanced the quenching efficiency of UiO-66-NH 2 , thus improving the sensitivity of the fluorescent aptasensor (UiO-66-TCPP vs. UiO-66-NH 2 : 0.0162 ng/mL vs. 1.8 ng/mL). In addition, we used UiO-66-TCPP to detect PAT in apple juice samples. This work provides a good paradigm for the construction of ratiometric fluorescence aptasensors with high sensitivity and accuracy.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Yumin Chen,Weiwei Cheng,Yuling Yang,Di Wu,Yan Zhang,Xiaozhi Tang
A versatile Surface-enhanced Raman Spectroscopy (SERS) aptasensor was fabricated for ultrasensitive and stable aflatoxin B1 (AFB1) detection using complementary DNA strands (cDNA) modified Fe 3 O 4 @UiO-66-NH 2 as capture probe and aptamer modified Au@ 4-MBA@AgNPs as signal probe . The surface of the Fe 3 O 4 beads was functionalized with UiO-66-NH 2 to improve the surface area and content of reactive amino groups for stable immobilization of cDNA and capture of more signal probes. Raman tag (4-mercaptobenzoic acid, 4-MBA) embedded Au@AgNPs nanoparticles (Au@4-MBA@AgNPs) was used as signal probes to achieve strong SERS intensity and protect the tag molecules from external interference. When no AFB1 existed, a strong SERS intensity of the signal probe was observed due to the DNA hybridization reaction between the capture and signal probe. While, the addition of AFB1 led to the dissociation of signal probes from the capture probes, leading to a decreased Raman intensity . As a result, a low limit of detection of 1.47 × 10 −7 ng/mL and wide linear range from 10 −6 to 10 2 ng/mL were obtained for determination of AFB1 based on the fabricated aptasensor. Moreover, an excellent selectivity and desirable recoveries from 94.3 % to 103.3 % in real maize samples were obtained, demonstrating the fabricated SERS aptasensor is promising in practical applications.
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APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Jiaqian Zhang,Jinjuan Xue,Zhenbo Wu,Mingxin Wang,Yiting Lv,Zhaoxia Chen,Shuaishuai Ma
In this work, we fabricated a multifunctional membrane by in-situ growth of tetrakis (4-carboxyphenyl) porphyrin-doped UiO-66-NH 2 on stainless steel mesh (SSM), denoted as TCPP/UiO@SSM, for gravity-driven oil–water/seawater mixtures separation and visible-light-driven bacterial inactivation. The as-prepared membrane exhibited high permeation flux (up to 46312 ± 1583 L m −2 h −1 ) as well as separation efficiency (above 98%) towards various oil–water/seawater mixtures separation, which resulted from the rough hierarchical structure and the inherent super-wettability. In particular, the membrane can effectively deal with viscous oil fouling to achieve a desired flux recovery ratio (FRR) after separating crude oil from water, attributing to the self-cleaning property originated from the photo-active TCPP/UiO. Furthermore, the as-fabricated TCPP/UiO@SSM has the ability to efficiently inactivate typical Gram bacteria (6 log units) in water under visible light . Both the oil–water separation and photocatalytic sterilization performances of TCPP/UiO@SSM are superior to UiO@SSM. The doping of photosensitive TCPP in UiO-66-NH 2 not only improved the hydrophilicity, but also enhanced the photocatalytic activity by creating a Z-scheme heterojunction to promote the separation of charge carriers and amplify the photothermal effect. This work provides a new platform for water disinfection and the treatment of oily wastewater containing viscous oil phase based on UiO metal–organic framework.
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Journal of Water Process Engineering
·
2022
·
IF 7.34
Mengjie Fu,Chun Wang,Guangwu Sun,Changfa Xiao,Ying Ding
3D flower-like UiO-66-NH 2 @ZiF-8 (UZ) nanoparticles have porous structural properties and multifunctional functional groups exposed on the surface, which provide significant advantages in improving compatibility with polymers and exceptional molecular sieve performance. Poly( p -phenylene terephthamide) PPTA is an acid/alkali resistant porous membrane material. However, the preparation of highly permeable and selective nanofiltration (NF) membranes is still a challenging problem due to the low permeability of PPTA NF membranes. Therefore, in this study, PPTA/UiO-66-NH 2 @ZiF-8 (PUZ) membranes were prepared using spacer spray-assisted interfacial polymerization. It was investigated that the effects of different additions of 3D flower-like UZ nanoparticles on the physicochemical properties and structure of PUZ membranes. The results showed that the polyamide structures with different morphologies were formed on the PUZ membranes surface by depositing 3D flower-like UZ nanoparticles at a spraying frequency of 12 min −1 . When 1.3 g/L of 3D flower-like UZ nanoparticles were interval sprayed, the PUZ4 membranes surface showed a unique doughnut-like structure and featured tubular and doughnut-like interconnections. PUZ4 membranes exhibited 4.4 times higher permeance and maintained excellent dye rejection (methylene blue dye permeance up to 58.23 L/m 2 ∙h∙MPa and methylene blue dye rejection of 99.60 %) compared to pristine PPTA NF membranes (methylene blue dye permeance up to 13.25 L/m 2 ∙h∙MPa and methylene blue dye rejection of 92.10 %). In addition, the modified PUZ4 membranes had a great antifouling performance with a recovery ratio of 99.43 % for more than 6 cycles and a high rejection rate of 98.51 % at 0.1 MPa.
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