JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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2019
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IF 2.983
Xinqi Zhu,Cheng Chen,Jiaquan Chen,Guangfu Xu,Yingxiang Du,Xiaofei Ma,Xiaodong Sun,Zijie Feng,Zhifeng Huang
In this study, a carboxymethylated-β-cyclodextrin-based chiral ionic liquid (CIL), tetramethylammonium-carboxymethylated-β-cyclodextrin (TMA-CM-β-CD) was successfully designed and synthesized. This cyclodextrin-based ionic liquids (ILs) was used as the sole chiral selector in capillary electrophoresis, and it is very interesting to find that the chiral separation capability can be remarkably improved when a conventional cyclodextrin chiral selector evolved into an IL chiral selector. The ionic liquid showed satisfactory separation performance towards twelve tested drugs. A series of parameters affecting the enantioseparation, such as the type and proportion of organic modifier, buffer pH, chiral selector concentration, as well as applied voltage were systematically investigated. Additionally, the molecular docking program Autodock was applied to further demonstrate the mechanism of chiral recognition and the enhanced enantioselectivity of TMA-CM-β-CD, which kept in agreement with our experimental results.
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JOURNAL OF CHROMATOGRAPHY A
·
2019
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IF 3.858
Hui Xu,Yingxiang Du,Zijie Feng,Xiaodong Sun,Jie Liu
Recently, in separation science, ionic liquids (ILs) have been commonly used as modifiers for buffer solutions, dynamic coating solutions, or coating solutions on carriers in capillary electrophoresis. However, only several papers have reported the use of chiral ILs as the sole chiral selector. In this paper, a chiral ionic liquid, cholinium-clindamycin phosphate (Ch-CP), was synthesized and employed as a sole chiral selector in capillary electrophoresis (CE). A series of parameters affecting the separation were optimized, including chiral selector concentration, buffer pH, proportion of organic modifier, as well as the applied voltage. Under the optimal conditions, compared to clindamycin phosphate (CP), the IL selector showed better enantioseparation capability and improved peak shapes for five racemic drugs. In addition, Molecular docking program Autodock was employed to elucidate the chiral recognition mechanism of Ch-CP, the computing results conformed to the experimental results.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2019
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IF 5.107
Congfei Yao,Yucui Hou,Ying Sun,Weize Wu,Shuhang Ren,Hui Liu
The extraction of aromatics from aliphatics with both high distribution coefficient ( D ) and high selectivity ( S ) is a challenge in the industry. Hydrophobic dicationic ionic liquids (DILs) were demonstrated as efficient extractants with both high D and high S . However, the high viscosity of the DILs may influence their application. In this work, we found that a hydrophobic DIL ([C 5 (MIM) 2 ][NTf 2 ] 2 ) could dissolve a small amount of water with a solubility of 2.24 wt% at 303.15 K. The viscosity and density of the DIL with different contents of water were investigated from 293.15 K to 333.15 K. A small amount of water in the DIL could decrease its viscosity greatly, while had little effect on its density. The effect of water content in the DIL on the extraction performance was studied, and it was found that both D and S remained high when a small amount of water dissolved in the DIL. The highest selectivity and distribution coefficient for toluene were 45.7, 0.86 (water content: 1.10 wt%) and 41.5, 0.75 (water content: 1.59 wt%), respectively. With increasing the carbon chain of aliphatics, both D tol and D ali decreased, but S increased in the presence of water. All the results indicated that the DIL with a small amount of water not only had high D and S simultaneously, but also enhanced the extraction process. Importantly, the use of water in the extraction process accords with the concept of green chemistry.
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EUROPEAN POLYMER JOURNAL
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2019
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IF 3.621
Xiaofeng Ma,Xiaoyu Lan,Linlin Wu,Lei Wang,Qun Gu,Yijun Shi,Xiaoli Gu,Zhenyang Luo
A series of well-defined random copolymers comprising butyl acrylate (BA) and 4-phenylazophenylmethacrylate (AzoMA) (P(AzoMA- r -BA)) are prepared successfully by reversible addition fragmentation chain transfer (RAFT) polymerization. P(AzoMA- r -BA)s show LCST-type phase transition in 1-butyl-3-methylimidazolium bis(trifluoromethanesulfone)amide ([C 4 mim][NTf 2 ]). LCST depends on the photoisomerization state of azobenzene, as well as on the AzoMA composition in the random copolymers. LCST of (P( cis -AzoMA- r -BA) is significantly higher than that of P( trans -AzoMA- r -BA), because cis -AzoMA and trans -AzoMA behave as solvato-philic and solvato-phobic comonomer, respectively. At a bistable temperature, photo-induced phase separation is completely reversible. Secondly, based on this phenomenon, a thermo-/photo- responsive ion gel (BA-AzoMA ion gel) can be prepared by free radical polymerization of BA and AzoMA using ethylene glycol dimethacrylate (EGDMA) as crosslinker in [C 4 mim][NTf 2 ]. BA-AzoMA ion gel shows high temperature contraction and low temperature expansion behavior, due to LCST-type phase behavior of polymer system consisting of AzoMA and BA. Contraction temperature of BA-AzoMA ion gel depends on photoisomerization state of the azobenzene group in polymers. At a bistable temperature, photo-induced expansion-contraction is reversible. Finally, a Photo-induced actuator can be realized using BA-AzoMA ion gel at suitable temperatures, featuring reversible bending by alternate irradiating with visible and UV light. The bending behavior is also demonstrated.
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Journal of Environmental Chemical Engineering
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2022
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IF 7.968
Jie Tian,Junyan Wei,Yeping Liang,Ruixue Guo,Beibei Li,Ruijuan Qu,Dongmei Zhou,Zunyao Wang,Ping Sun
This study aimed to investigate the catalytic performance of Fe 3 O 4 /ZnO in the ozonation of 1-hexyl-3-methyl imidazolium bromide ([HMIM]Br). The Fe 3 O 4 /ZnO composite was prepared by a quick and convenient two-step coprecipitation method, and the optimum mass ratio of Fe 3 O 4 :ZnO was determined as 1:8. The structure, surface morphology, and chemical composition of the Fe 3 O 4 /ZnO composites were studied by characterization methods. The degradation efficiency of [HMIM]Br reached 96% in 5 min in catalytic ozonation with the Fe 3 O 4 /ZnO composite, an increase of 20% compared with ozonation alone. Moreover, the pseudo-first-order rate constant was 1.5 times higher than ozonation alone. With the increase in the catalyst dosage, the degradation efficiency of [HMIM]Br first improved and then decreased, and the optimum dosage was 0.25 g/L. The increase in pH value and the introduction of Cu 2+ effectively promoted the catalytic ozonation of [HMIM]Br with Fe 3 O 4 /ZnO, while the reducing inorganic ions inhibited the ozonation reaction. Different water matrices had little influence on the catalytic performance of Fe 3 O 4 /ZnO. Radical scavenging and EPR experiments showed that hydroxyl radicals (•OH), superoxide radicals (O 2 •- ) and singlet oxygen ( 1 O 2 ) were the main active species in this system. Meanwhile, product identification showed that the degradation of [HMIM]Br mainly included hydroxylation, imidazole ring cleavage and bond cleavage. Toxicity prediction illustrated that the catalytic ozonation of [HMIM]Br could effectively reduce its toxicity. The efficiency, toxicity, reusability, and stability experiments suggested that the developed catalyst, Fe 3 O 4 /ZnO composite, had promising prospects in catalytic ozonation.
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AIP Advances
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2023
·Vol. 13
·期 12
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IF 1.6
Liu Yuting,Chen Yiming,Liang Jianlin,Zhao Jianyuan,Li Kang,Zhao Weiwei
In this study, we explored the impact of ionic liquid gating on YBa 2 Cu 3 O 7−x superconductivity. We observed that direct contact of YBa 2 Cu 3 O 7−x and the ionic liquid N-diethyl-N-methyl-N-(2methoxyethyl)ammonium bis(trifluoromethanesulfonyl)imide (DEME-TFSI) results in irreversible electrochemical reactions, despite the application of a relatively low gate voltage at 220 K. Capping a thin layer of boron nitride (BN) on YBa 2 Cu 3 O 7−x enabled a reversible modulation of carrier density at 300 K. Benefiting from the higher ion mobility of ionic liquid at 300 K, this modification led to more than a one-time increase in carrier density, a 3-time improvement in voltage modulation efficiency, and a reversible tuning of the superconducting temperature. These findings suggest that using a BN capping layer holds promise for enhancing the stability and efficiency of devices using ionic liquid gating.
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HYDROMETALLURGY
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2023
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IF 4.7
Nian Zhang,Fujian Li,Haiyang Xue,Zhongzhi Wang,Sen Qiu,Bangyu Fan,Yanyan Cheng,Xiangping Zhang
Aluminum (Al) is often associated with rare earth resources, and the removal of Al 3+ from rare earth elements (REEs) is a difficult task due to its amphoteric properties. Aluminum ions (Al 3+ ) enrich in Sm 3+ -Gd 3+ solution with the traditional 2-Ethylhexylphosphoric acid mono-2-ethylhexyl ester (P507)-kerosene-HCl system, emulsifying the phases, polluting the rare earth products and reducing the separation efficiency. A readily industrialized ionic liquid (IL) was synthesized with methyltrioctylammonium chloride ([N1888]Cl) and industrial naphthenic acid (NA) for the purification of Al 3+ from GdCl 3 solution. Under the experimental conditions, the extraction properties of diluted [N1888][NA], diluted NA and saponified NA were comparatively investigated and the separation factors ( β Al/Gd ) of Al/Gd were 23.0, 3.5 and 1.3, respectively. The effects of the salting-out agent, extraction agent, pH value and phase ratio on metal extraction efficiency were optimized. Finally, the industrial GdCl 3 feed with a high Al 3+ impurity of 889 mg/L was lowered to 5 mg/L. The removal efficiency of Al 3+ was 99.4%, and the purity of Gd 3+ was 99.998%. It provides a potential method for Al 3+ purification from rare earth solutions with advantages of high efficiency, raw materials availability and ready industrialization.
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ACS Applied Polymer Materials
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2023
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IF 5
Liping Liang,Yuanqi Wang,Weirong Ren,Xinpei Gao,Liqiang Zheng,Fei Lu
Ionic liquid (IL)-based aqueous two-phase systems (ATPSs) are formed by the phase separation of aqueous mixture of ILs. Owing to their unique interfacial properties and stable interfacial zone, IL-based ATPSs can work as a promising confined space for membrane processing. Herein, for the first time, we proposed the thermoresponsive IL-based ATPSs as a platform for synthesizing covalent organic framework (COF) membranes. Upon the formation of aqueous biphasic interface at a corresponding temperature, the monomers and catalysts were separately dispersed in the IL-rich phase and water-rich phase. Due to the high viscosity of IL-rich phase and hydrogen bonding interactions in water-rich phase, the diffusion of both aldehyde and amine monomers could be controlled simultaneously and react within the aqueous biphasic interface zone. By optimizing the interfacial properties, the tight and crystalline COF membranes can be achieved with ultrahigh solvent flux and exceptional dye retention performance (>98.0%). For comparison, the homogeneous IL solution realized by temperature without affecting the integrity of the biphasic system was also applied as the medium for COF synthesis and only COF powders with low crystallinity can be obtained. As the pioneering exploitation to fabricate COF membrane at the IL-based aqueous biphasic interface, this work would supply a guiding direction for the green membrane processing strategy.
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MICROPOROUS AND MESOPOROUS MATERIALS
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2023
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IF 5.2
Fangfang Li,Yueyue Hu,Yong Cheng,Ying-Hua Zhou
Exploiting an effective catalyst for CO 2 conversion into value-added chemicals under mild circumstances still remains a challenge. Herein, UiO-66 decorated with ionic liquids (ILs) (denoted as UiO-66-ILs) were facilely synthesized by the mixed ligands of 1,4-benzene dicarboxylic acid and pyridyl-containing mono-carboxylic acid isomer (including nicotinic acid (NA), isonicotinic acid (INA), and 2-pyridine carboxylic acid (PCA)), followed by the further modification with different bromoalkanes. Among various UiO-66-ILs, UiO-66 derivative containing the ILs composed of PCA and bromoethane (named as UiO-66-ILs(PCA-EtBr)) displayed superior catalytic performance on CO 2 -epichlorohydrin cycloaddition into chloropropene carbonate, with a high yield of 90 % under 0.1 MPa CO 2 at 110 °C without the addition of any solvent and cocatalyst. Whereas, UiO-66-ILs(NA-EtBr) and UiO-66-ILs(INA-EtBr) as analogues of UiO-66-ILs(PCA-EtBr) presented a low yield of 77 % and 67 %, respectively, unveiling that the orientation of carboxyl at monocarboxyl pyridine ligand played a great influence on the catalytic activity. The excellent activity of UiO-66-ILs(PCA-EtBr) was attributed to the synergetic effect of Lewis acidity from MOF nodes for activating C–O bond of epoxide, CO 2 absorption by pyridyl moiety, and nucleophilicity of ILs decoration. In addition, UiO-66-ILs(PCA-EtBr) exhibited a broad scope of epoxide substrate, as well as a great recyclability. Moreover, a possible catalytic mechanism was proposed for CO 2 conversion into cyclocarbonate.
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FUEL
·
2023
·
IF 7.4
Yaping Liu,Chao Pan,Xiaomin Qiu,Xianjie Li,Hengjun Gai,Meng Xiao,Tingting Huang,Quanhong Zhu,Hongbing Song
Although fossil fuels bring convenience to the production and life of people, they also cause numerous environmental problems. As a result of overexploitation, fossil fuels are gradually being depleted as a nonrenewable resource. Biomass is a green and renewable resource and has attracted people’s attention. As a platform compound derived from renewable biomass, 5-hydroxymethylfurfural (HMF) is important for in-depth research. The oxidative esterification process from HMF to dimethyl furan-2,5-dicarboxylate (FDMC) was achieved using a gold (Au) nanoparticle (NP) catalyst supported on poly(ionic liquid)s (PILs). The comprehensive characterization of the synthesized catalyst showed that the Au NPs were successfully loaded on PILs, and a strong interaction occurred between the catalyst support and the metal. In this work, 10 %Au/PILs-Cl-1 was used as the best catalyst. The conversion of HMF ( C HMF ) and the selectivity to FDMC ( S FDMC ) reached 95.08 % and 96.82 %, respectively, under the conditions of 120 °C, 1.5 MPa, 12 h, and 0.5 equiv. CH 3 ONa. In addition, cycling experiments indicated the stability and successfully recycling of 10 %Au/PILs-Cl-1 catalyst.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2023
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IF 8.6
Yunfei Yu,Xue Yang,Chenchen Zhang,Jie Chen,Wei Lin,Jianqiang Meng
Ion gel membranes show great potential for carbon capture due to their excellent solubility selectivity for CO 2 . However, poor mechanical properties and limited stability as well as low gas permeability limit their application. Here, we report a environmentally friendly and simple strategy for preparing double-network(DN) ion gel membranes with both high strength and excellent gas separation performance. We use a “one-pot method” that the first network(FN) and the second network(SN) with ionic liquid were mixed evenly, and the DN membrane was prepared under heating and UV light. Wherein the FN was obtained by a ring-opening reaction between O, O-bis(2-aminopropyl) polypropylene glycol-block-polyethylene glycol-block-polypropylene glycol and a trimethylolpropane triglycidyl ether. And the SN was obtained by free radical polymerisation between 1 and vinyl-3-ethylimidazole bis(trifluoromethanesulfonyl)imide and a p -divinylbenzene (DVB) crosslinker. The crosslinking density of FN and SN, the mass ratio of the FN to the SN, as well as the content and type of free ionic liquid were optimized to improve the mechanical and gas separation properties of the DN membrane. When the crosslinking groups reacted quantitatively, the tensile strength of DN membranes is 1.5 MPa and the elongation at break is 120 %. With the increase of free ILs content, the crystallinity as well as the glass transformation temperature of the DN membrane decreases and the CO 2 permeability increases (PCO 2 :866 Barrer α (CO 2 /N 2 ):31). When 1-ethyl-3-methylimidazolium dicyanamide was used, the CO 2 /N 2 separation performance can surpass the 2008 upper bound (PCO 2 :464 Barrer α (CO 2 /N 2 ):63). The DN membrane has better gas separation and mechanical properties than the SN membrane and shows superior combination of the permeability and selectivity. This research provides a new approach designing a tough ion gel membrane which shows great potential for practical application in carbon capture.
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Advanced Energy Materials
·
2023
·Vol. 13
·期 45
·2302443
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IF 27.8
Kai Ding,Elijah J. Begin,Shouyi Yuan,Mingyang Zhong,Yang Wang,Yingjie Zhang,Xiaoyuan Zeng,Junwei Lucas Bao,Yonggang Wang
Given the high compatibility with Li metal anodes, ethereal electrolytes have found widespread use in Li metal batteries. Unfortunately, their applications in high-voltage Li metal batteries are hampered by a limited electrochemical window. In this study, a diluted ethereal electrolyte (with Li salt concentration < 1.5 m ) is developed containing 1 m lithium bis(fluorosulfonyl) imide (FSI) and 0.3 m LiNO 3 in a N -methyl- N -propylpiperidinium bis(trifluoromethanesulfonyl)imide (PP13TFSI):dimethyl ether (DME) (v:v = 1:4) mixture for Li metal batteries with an aggressive high-voltage cathode via the formation of an anion-enriched solvation sheath. In contrast to high-concentration electrolytes, the formation of the anion-enriched solvation sheath in this design is facilitated by the addition of ionic liquids. Further theoretical calculations indicate that the presence of FSI − and NO 3 − anions in the first solvation sheath weakens the desolvation energy of the DME solvent, suggesting a faster desolvation process at the electrode interphase. Consequently, the designed electrolyte enables long-term cycling of Li || LiNi 0.8 Co 0.1 Mn 0.1 O 2 (NCM811) full cells over 1000 cycles at a high rate of 10 C. More notably, it also allows for a long cycle life of 100 cycles under a high rate of 5 C, even with limited negative capacity to positive capacity (N/P) ratio of 1.
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