Catalysis Science & Technology
·
2020
·Vol. 10
·期 6
·1609-1618
·
IF 5.721
Chao Zhang,Jiandong Liu,Xingliang Liu,Shiai Xu
Two novel covalent bond photocatalysts, namely, g-C3N4NSs/TC1 and g-C3N4NSs/TC2 were prepared for the first time via the generation of an amide covalent bond between g-C3N4 nanosheets (g-C3N4NSs) and acyl chloride synthesized from triphenylamine-type dyes, 2-cyano-3-(4-(diphenylamino)phenyl)acrylic acid (TC1) or 3,3′-(4,4′-(phenylazanediyl)bis(4,1-phenylene))bis(2-cy-anoacrylic acid) (TC2). The experimental results indicated that triphenylamine D–π–A-type organic dye moieties covalently bonded to g-C3N4 successfully and the spectral response regions of both g-C3N4NSs/TC1 and g-C3N4NSs/TC2 could be extended from ∼460 nm to more than 600 nm. Due to the introduced amide covalent bond, the constructed g-C3N4NSs/TC1 photocatalyst showed remarkably enhanced H2 evolution activity with about 73 555.8 μmol h−1 g−1 and exhibited high apparent quantum yields (AQY) of 35.2%, 27.1%, 16.9% and 5.4% at 420 nm, 500 nm, 520 nm and 600 nm monochromatic light, respectively. Compared with the results for pure g-C3N4 NSs, about 100 times higher H2 production rate and 978 times higher AQY value were obtained for g-C3N4NSs/TC1 with the amide covalent bond under visible light irradiation. Compared to g-C3N4NSs/TC1, g-C3N4NSs/TC2 exhibited slightly lower H2 evolution activity with about 70 986.8 μmol h−1 g−1. Combining the experimental and density functional theory (DFT) calculation results, a possible mechanism can be conjectured that the electronic and geometric structures of g-C3N4NSs/TC1 are more conducive to the charge separation and the unidirectionality of electron transport in the excited state than those of g-C3N4NSs/TC2. The research reveals that this introduction of simple triphenylamine-type dyes into the surface of g-C3N4via covalent links results in a strong covalent interaction between functionalized moieties and g-C3N4 to synergistically improve the electronic and optical properties and photocatalytic performance. The present work highlights the potential use of organic dye covalent-functionalized g-C3N4via post modification as a novel photocatalyst in applications such as H2 production.
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JOURNAL OF MOLECULAR LIQUIDS
·
2021
·
IF 6.165
Yannan Du,Hongjun Zang,Yimo Feng,Kai Wang,Yaxin Lv,Zhipeng Liu
This paper briefs the emerging strategies for the designing of catalytic systems, which direct conversion of chitin biomass monomer N -acetyl- d -glucosamine (NAG) to 3-acetylamino-5-acetylfuran was studied systemically. Twelve catalysts were investigated, and pyrazine hydrochloride ([Pyz]Cl) ionic liquid exhibited the good performance-achieving 3A5AF with yields of 36.94% from NAG . Further adding boric acid and CaCl 2 , treating at 190 °C for 60 min, the conversion rate of NAG is 100%, and the yield of 3A5AF can be increased to 69.54% in DMA. Furthermore, functional group changes before and after the reaction have been characterized by FTIR, HPLC-MS and 13 C NMR were applied to monitor the reaction process with [Pyz]Cl as the catalyst. The reactive intermediate was clearly detected by these techniques. Accordingly, a possible reaction pathway was proposed. The results of this experiment provide a mild and efficient reaction route for the degradation of biomass, and enrich the theoretical research of quaternary amine catalysts in the conversion of biomass waste into high value-added chemicals.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2025
·
IF 6.2
Meilan Xue,Xuehan Zhang,Yifan Zhou,Jiayi Yan,Haiqi Gao,Yixian Bai,Jing Shi,Yuhan Liu,Yan Xu,Nan Zhang,Lu Li,Shaobo Shi,Hui Liang
This study was aimed to reveal the neuroprotective effect of sulfated fucooligosaccharides (FOS) in an aging mouse model induced by d-galactose. The results showed that FOS treatment ameliorated inflammation, improved behavioral decline in memory and cognition, and exerted neuroprotective effects. FOS reduced microglia activation by decreasing the expression of P38 mitogen-activated protein kinase (P38 MAPK), cyclic-AMP response binding protein (CREB), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2). In addition, FOS improved intestinal mucosal barrier damage and reduced the release of lipopolysaccharide. FOS increased the diversity of the gut flora and promoted a significant enrichment of the Akkermansia genus. FOS also increased the butyric acid level and reduced the expression of histone deacetylase 3 (HDAC3), Toll-like receptor 4 (TLR4), and nuclear factor kappa-B (NF-κB). Fecal microbiota transplantation from the FOS-treated mice showed a similar effect to FOS treatment in inhibiting neuroinflammation and reduced d-galactose-induced cognitive dysfunction. The results suggested that FOS supplementation ameliorated d-galactose-induced neuron damage and exerted neuroprotective effects through the gut–brain axis.
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Journal of Materials Chemistry A
·
2023
·Vol. 11
·期 26
·14311-14319
·
IF 11.9
Lantao Liu,Ziyu Sun,Yaping Lu,Jiapeng Zhang,Yiming Li,Gaixia Zhang,Xiaohong Chen,Sasha Omanovic,Shuhui Sun,Huaihe Song
Due to the environmental friendliness and high safety of aqueous Zn-ion hybrid capacitors (ZIHCs), the exploration of high-performance porous carbon electrodes for ZIHCs has recently attracted significant attention. However, most of the reports focus on the preparation method and modification of porous carbon, and rarely explore the mechanisms of material synthesis/fabrication in the carbonization process. In this study, we developed a simple self-template method for preparing N-doped porous carbon from D-calcium pantothenate (DCP). More importantly, the morphology evolution, heteroatom doping, and defect generation of the DCP during carbonization are clarified. Based on a clear understanding of the carbonization mechanism, assisted by DFT theoretical simulations, we find the optimal carbonization temperature of the DCP-derived porous carbon for ZIHCs. The assembled ZIHCs exhibit excellent rate performance (140 mA h g−1 at 0.2 A g−1 and 86.2 mA h g−1 at 6.4 A g−1), and high energy density and power density (111.1 W h kg−1 and 4835.2 W kg−1, respectively). This work provides a constructive avenue for designing high-performance ZIHC electrode materials.
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ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Qi Huang,Liping Guo,Ning Wang,Xiang Zhu,Shangbin Jin,Bien Tan
Conjugated microporous polymers (CMPs) with high surface areas, tunable building blocks, and fully conjugated structures have found important applications in optoelectronics. Here, we report a new series of CMPs with tunable band gaps by introducing thiazolo[5,4-d] thiazole as the linkage. Because they are synthetic polymers, the geometries and structures could be rationally designed. Their intrinsic wide visible-light absorption properties and layered architectures endow them with a promising photocatalytic performance. The role of geometries, surface areas, and morphologies of the CMPs in photocatalysis abilities is examined and discussed. The results indicate that geometries have a direct impact on the surface areas and morphologies of the CMPs and thus exert great influence on photocatalysis.
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SYNTHETIC METALS
·
2014
·
IF 2.222
Peng Liu,Chao Yang,Xue Wang,Jinshan Guo,Baohua Hou
A facile method was developed for growing the alignment of polyaniline (PANI) nanofibers on three-dimensional (3-D) templates, via the chemical oxidative polymerization of aniline in dilute solution at 0–5 °C in presence of sulfonated polystyrene (SPS) microspheres and hydrochloric acid as template and dopant, respectively. Then the “hairy” PANI hollow microspheres were obtained after etching the templates with toluene. It was found that the formation of the “hairy” PANI hollow microspheres could be well controlled by altering the template concentration, thus the possible formation mechanism was deduced. The unique “hairy” PANI hollow microspheres prepared with the template concentration of 2.0 mg mL −1 possessed the specific capacitance of 298 F g −1 and the capacitance retention of 63.6% after 900 cycles.
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JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
·
2026
·
IF 1.6
Fen Qiu,Xue-Qin He,Yi-Zhang Li,Chun-Feng Wu,Du-Dong Wei,Hao-Yu Liu,Li-Ba Xu
We established in vivo models of hippocampal oxidative injury to investigate the protective effect of Angelica dahurica polysaccharide (ADP) on the hippocampus. ADP alleviated ovariectomized/D-Galactose (OVX/D-Gal)-induced hippocampal damage and enhanced antioxidant capacity (increased SOD/GSH-Px, decreased MDA). Additionally, ADP activated the Nrf2 pathway (upregulated Nrf2, downregulated NQO1/HO-1) and inhibited apoptosis (upregulated Bcl-2, downregulated Bax/cleaved caspase-3). Untargeted metabolomics revealed that ADP reversed seven oxidative stress-related metabolites, and pathway analysis implicated glycerophospholipid metabolism in its antioxidant mechanism. These results demonstrated that ADP protects against OVX/D-Gal-induced hippocampal oxidative injury by activating Nrf2, enhancing antioxidant capacity, inhibiting apoptosis, and regulating glycerophospholipid metabolism.
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Foods
·
2022
·Vol. 11
·期 3
·386
·
IF 5.561
Ying Xu,Xuan Yu,Jiaqi Gui,Yiqun Wan,Jinping Chen,Ting Tan,Fan Liu,Lan Guo
A rapid and effective ultra-high performance liquid chromatography (UHPLC) method was developed for the determination of five anthraquinones (emodin, physcion, aloe-emodin, rhein, and chrysophanol) inPolygonum multiflorum. The target compounds were ultrasonically extracted with 70% methanol, followed by dispersive solid-phase extraction (d-SPE) with HC-C18 and desorption with acetonitrile. The five anthraquinones were separated on an ACQUITY UPLC®HSS T3 column (2.1 × 100 mm, 1.8 μm) and detected by a photodiode array detector (PDA) at 254 nm. Under the optimized conditions, linear relationships were achieved in the range of 0.3~100 mg/L for emodin, 0.3~40 mg/L for physcion, 0.1~20 mg/L for aloe-emodin, and 0.05~20 mg/L for rhein and chrysophanol. The limits of detection of the five analytes ranged from 0.01 to 0.08 mg/L, and the recoveries were within the range of 82.8~118.4% with an RSD (n= 6) of 1.0~10.3%. The intra-day and inter-day precision (n= 5) of the five targets were in the range of 1.0~1.8% and 3.0~3.1%, respectively. Furthermore, this method was applied to analyses ofPolygonum multiflorumsamples collected from different regions in China with satisfactory results. All the results indicated that this method is suitable for the detection of five anthraquinones inPolygonum multiflorum.Keywords:anthraquinones;Polygonum multiflorum;d-SPE;UHPLC
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DYES AND PIGMENTS
·
2023
·
IF 4.5
Qiushuang Li,Bing Zhao,Xiangdong Kong,Liyan Wang,Wei Kan,Bo Song,Rui Yu,Pengfei Zhang
Designation and application of the luminescent COFs remains a tough challenge and imperative task because of their limited building block structure, the unavailable raw material, the tedious modification process, or the onefold sensing function. Herein, a fluorinated fluorescent covalent organic framework containing a phenanthro[9,10- d ]imidazole moiety [TFPB-PI(F)–COF] had been successfully designed for Cu 2+ and Al 3+ detection relayed by PO 4 3− . TFPB-PI(F)–COF serves as a highly sensing platform with the superior selectivity toward Cu 2+ and Al 3+ based on the coordination interaction and the chelation enhancement quenching (CHEQ) effect, and the detection limits are 2.3 and 4.2 n mol L −1 , respectively. Subsequently, accompanied with the gradual introduction of PO 4 3− , TFPB-PI(F)–COF@M (Cu 2+ and Al 3+ ) complex is wrecked due to electrostatic attraction with the detection limit of 10 n mol L −1 , led to the fluorescent recovery of TFPB-PI(F)–COF. Furthermore, the reversible fluorescent performance by the mode of “on–off–on” is perfect. Besides, the established relayed method can be successfully employed for the analysis of Cu 2+ and Al 3+ in environmental water samples with recoveries of 96.00–104.63 % and RSD <4.62 %. Moreover, the fluorescent images for the visual detection of Cu 2+ is also fabricated in living HeLa cells, which provides a modest contribution and an effective platform to the biological analysis.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2020
·Vol. 21
·期 5
·1836
·
IF 4.556
Kaiyue Sun,Yingting Sun,Heyang Li,Dongyao Han,Yuting Bai,Rong Zhao,Zijiao Guo
We aimed to study the effects of an ethyl acetate fraction ofPhysalis alkekengi(PAE) ond-galactose (d-gal)-induced senescence and the underlying mechanism. Firstly, analysis of the phytochemical composition revealed total flavonoids, total phenolics, total saponins, rutin, and luteolin contents of 71.72 ± 2.99 mg rutin equivalents/g, 40.19 ± 0.47 mg gallic acid equivalents/g, 128.13 ± 1.04 mg oleanolic acid equivalents/g, 1.67 ± 0.07 mg/g and 1.61 ± 0.01 mg/g, respectively. The mice were treated withd-gal for six weeks, and from the fifth week, the mice were administered with PAE by gavage once a day for five weeks. We found significantd-gal-induced ageing-related changes, such as learning and memory impairment in novel object recognition and Y-maze, fatigue in weight-loaded forced swimming, reduced thymus coefficient, and histopathological injury of the liver, spleen, and hippocampus. The PAE effectively protected from such changes. Further evaluation showed that PAE decreased the senescence-associatedβ-galactosidase of the liver, spleen, and hippocampus, as well as the oxidative stress of the liver, plasma, and brain. The abundance of flavonoids, phenols, and saponins in PAE may have contributed to the above results. Overall, this study showed the potential application of PAE for the prevention or treatment of ageing-associated disorders.Keywords:Physalis alkekengi;learning and memory;exercise endurance;cellular senescence;oxidative stress
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JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2020
·
IF 2.734
Qihong Zhang,Wei Ren,Alexandr V. Dushkin,Weike Su
Olmesartan medoxomil (OM) has been used in treatment of hypertension disease, as a prodrug of olmesartan. However, its clinical application is limited by the low oral bioavailability (~28%). Ternary solid dispersion of OM was prepared with hydroxypropyl- β -cyclodextrin and N -methyl- d -glucamine to improve its oral bioavailability using roll mill ML 007. Its physicochemical characterization was measured by scanning electron microscope, differential scanning calorimetry , powder X-ray diffraction and transform infrared spectroscopy . The solutions properties of OM in ternary solid dispersion were investigated involving the solubility, dissolution profiles, 1 H NMR analysis, phase solubility study and PAMPA study. Instrument analysis results revealed an amorphous solid dispersion had been synthesized without any side-products. It also showed enhanced solubility and dissolution rate in vitro . Pharmacokinetic study demonstrated an improved oral bioavailability in vivo . The rapid storage assay showed that the chemical stability of inclusion complexes had no change. The synthesized OM ternary solid dispersion is promising to be a better alternative to its pure formation in the market with improved oral bioavailability.
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JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
·
2021
·Vol. 109
·期 12
·2506-2515
·
IF 4.396
Jing Wei Jin,Min Zhi Rong,Ming Qiu Zhang,Wing-Leung Wong
β-1,3-D-glucan has been reported to have a series of bioactivities including antitumor, antimicrobial, anti-inflammatory and antioxidative effects; however, its insolubility in neutral aqueous solution significantly restricts the potential application in biological and medicine fields. Herein, a water-soluble aminated β-1,3-D-glucan (AG) was synthesized and the anti-inflammatory effect, cytotoxicity and plasmid DNA (pDNA) binding capacity of AG, serum stability, the particle sizes and zeta potentials of AG/pDNA nanocomposites, and the transfection efficiency and mechanism of action were studied. AG shows no obvious cytotoxicity within the range of working concentration (1–64 μg/ml) and it exerts potent anti-inflammatory effect independent on Dectin-1 and TLR2. AG/pDNA nanocomposites prepared by electrostatic interaction possess an appropriate particle size ranged from 192.8 to 118.4 nm and zeta potentials ranged from 20.880 to 27.16 mV with the N/P ratios from 5 to 100. AG/pDNA nanocomposites at the N/P ratios of 10 and 20 were able to show superior transfection efficiencies in RAW 264.7 cells as a result of their suitable particle size, zeta potential, anti-inflammatory effect, and the specific interaction with pattern recognition receptors (Dectin-1 and TLR2). These results indicate that AG is a potential candidate for DNA delivery system due to its potent anti-inflammatory effect and high transfection efficiency.
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