BIOMACROMOLECULES
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2023
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IF 6.2
Qizhen Zheng,Jinhan Sheng,Ji Liu,Xianghan Chen,Ming Wang
Biomineralization of metal–organic frameworks (MOFs) provides a powerful approach for intracellular protein delivery, enabling the study of biological function and therapeutic potential of proteins. However, the potency of this approach is largely challenged by the low efficiency of current strategies for interfacing proteins with MOFs for biomineralization and intracellular delivery. Here, we report a versatile and convenient biomineralization strategy for the rapid encapsulation and enhanced delivery of proteins using MOFs, accelerated by histidine-rich proteins. We demonstrate that the histidine-rich green fluorescent protein (H39GFP) can accelerate the biomineralization of MOFs by promoting the coordination between proteins and metal ions, leading to enhanced protein delivery efficiency up to 15-fold. Moreover, we show that the delivery of H39GFP-fused cytotoxic ribonuclease and bacterial-derived RAS protease can effectively inhibit tumor cell growth. The strategy of promoting the biomineralization of MOFs via histidine-rich proteins for enhanced intracellular delivery could be expanded to other biomacromolecules, advancing their therapeutic potential and the biomedical scope of MOFs.
研究领域:
生物医学工程
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材料科学
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生物化学
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癌症研究
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DOI
PubMed
高影响因子
Materials Today Sustainability
·
2023
·
IF 7.8
L. Xie,J. Ding,X. Kong,J. Qin,J. Wang
With the development of modern industry and increasing population around the world, the overuse of fossil fuels for energy supply has produced large amounts of CO 2 in the atmosphere. Metal-organic frameworks (MOFs) with tailorable structures and developed porosity have emerged as promising candidates for CO 2 adsorption and separation. However, the synthesis of MOFs by conventional hydrothermal method faces challenges like low crystallization rate and yield, which limits their industrial application for gas adsorption. In this work, a highly efficient microwave (MW)-assisted method was employed for the synthesis of Mg-gallate. The effects of MW conditions on the structure, morphology, and CO 2 adsorption properties of Mg-gallate were systematically investigated. The highest CO 2 adsorption performance (5.37 mmol g −1 at 298 K and 1 bar) was achieved on the Mg-gallate synthesized at 100 °C for 20 min under an MW power of 100 W. The obtained Mg-gallate also exhibited high adsorption selectivity of CO 2 over N 2 (1500) and superior recyclability . Furthermore, the Mg-gallate@PEI composite beads were designed by incorporating the MOF crystals into the polymeric matrix in order to satisfy the industrial application demands. The combined advantages of rapid MW synthesis, excellent adsorption performance, and shaping make the Mg-gallate a promising material for practical CO 2 capture.
研究领域:
化学工程
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材料科学
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环境科学
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能源科学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2017
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IF 6.216
Yijun Xue,Wei Sun,Qian Wang,Limei Cao,Ji Yang
MOFs (metal-organic frameworks) are stable materials with both organic and inorganic pores, and possess high surface area fascinating structures. Owing to the unique octahedral of aluminum center and strong Al–O bonds, Al-based MOFs show excellent thermal stability. In this paper, MIL-96(Al) is proved to be effective at dispersing Pt particles evenly and sparsely as it is employed as catalyst support. MIL-96(Al) is synthesized via a water based route and different contents of Pt particles are directly deposited on the surface of MIL-96 in one step by hydrothermal method to prepare Pt X MIL-96 (x represents Pt content) catalysts. The catalyst are sprayed evenly on carbon paper, with Pt content of 0.03%, 0.11%, 0.27% and 0.41%, respectively, and are applied in a gas diffusion reactor with snakelike flow field for low temperature H 2 -SCR. For Pt 5 MIL-96/CP, the NO removal efficiency can reach up to 100% at 60 °C. Electron transfer between Pt and MIL-96 is observed via X-ray photoelectron spectron (XPS). It reveals that the deposited Pt is in metallic state. Meanwhile, the electronic structure of MIL-96 is kept intact in the process of Pt depositing. The excellent performance of Pt 5 MIL-96/CP catalyst strongly suggests its potential application.
研究领域:
材料科学
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环境科学
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催化化学
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DOI
高影响因子
JOURNAL OF LOSS PREVENTION IN THE PROCESS INDUSTRIES
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2026
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IF 4.8
Qi Cheng,Chongyang Du,Tingting Chen,Yong Pan,Juncheng Jiang
Epoxy resin (EP), a widely utilized thermosetting polymer, is inherently flammable and poses significant fire hazards. Drawing inspiration from the surface chemistry of mussels, this study presents the fabrication of biomimetic flame-retardant microcapsules, termed PDA@MOFs (M = Cu, Fe, Co) at room temperature and pressure for meeting the requirements of intrinsic safety. These microcapsules were synthesized through the oxidative self-polymerization of dopamine (DA) under alkaline conditions, resulting in polydopamine (PDA) on the surface of metal-organic frameworks (MOFs). We incorporated these PDA@MOFs into EP matrix to evaluate their impact on the mechanical and flame-retardant properties of EP composites. Compared to unmodified EP/MOFs, EP/PDA@MOFs exhibited enhanced interfacial compatibility and improved mechanical performance. Limiting oxygen index (LOI), vertical burning (UL-94), and cone calorimetry test (CCT) confirmed that PDA@MOFs significantly enhanced the flame retardancy and smoke suppression. Among them, EP/PDA@Co-MOF demonstrated the best performance, achieving a 32.2% reduction in peak heat release rate (pHRR) and a 14.2% decrease in total heat release (THR) compared to neat EP. Furthermore, residual char analysis revealed that the flame-retardant mechanism involved physical barrier effect, catalytic char formation, and radical trapping, establishing a foundation for designing high-performance flame-retardant EP composites.
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DOI
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
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2026
·
IF 4
Ying Wang,Yi-Tong Du,Wen-Bo Yan,Zi-Tao Jiang,Jin Tan
BACKGROUND Cherry tomatoes are prone to postharvest deterioration and spoilage at room temperature, whereas chemical preservatives pose safety and environmental risks. Clove essential oil (CEO) has excellent antibacterial activity but is limited by high volatility, poor water solubility and dosage sensitivity. Cyclodextrin metal-organic frameworks (β-CD-MOFs) can improve CEO stability, but their poor processability and aqueous dispersibility hinder fruit preservation applications. Chitosan (CS), a natural hydrogel with film-forming and antibacterial properties, offers an ideal matrix to address these limitations. RESULTS A CEO-loaded CS/β-CD-MOFs composite coating (CS-CEO/MOFs) was constructed and evaluated on cherry tomatoes stored at 25 °C via physicochemical analysis, electronic eye color detection and texture profile analysis (TPA). Compared with control, CS and high-concentration CEO-chitosan (CS-CEO-H) groups, high-concentration CS-CEO/MOFs (CS-CEO/MOFs-H) delayed spoilage. Principal component analysis of electronic eye data showed the recognition index (a parameter reflecting the distinguishability of color characteristics among groups) increased from −3 (day 0) to 97–98 (days 6–21), indicating distinct inter-group ripening rate differences. TPA results indicated CS-CEO/MOFs-H slowed hardness decline (effect positively correlated with hydrogel concentration) and maintained higher soluble sugar, vitamin C and titratable acid contents, as well as reduced weight loss, extending room-temperature shelf life to 21 days. CONCLUSION The CS-CEO/MOFs coating combined the gas barrier property of CS and the controlled release capability of β-CD-MOF, forming a synergistic fresh-keeping mechanism. As a safe, natural preservative, it provides a promising solution to reduce cherry tomato postharvest losses and lays a foundation for the development of plant-derived composite preservatives with controlled-release and gas barrier synergistic properties. © 2026 Society of Chemical Industry.
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高影响因子
MICROCHEMICAL JOURNAL
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2025
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IF 5.1
Xinmei Qian,Chunxiang Li,Mingyu Zheng,Keqin Deng
A flower-like S, N-codoped carbon nanosheets loaded with hybrid magnetic nanoparticles (HMNPs/S,N-CNSs) by using MOF as precursor was prepared. The morphology, composition, microstructure, and property were evaluated by SEM, HRTEM, EDS, XRD, XPS, magnetic analysis, and cyclic voltammetry. The hybrid nanoparticles were composed of most Fe 3 O 4 , some CoFe alloy, and a few Fe 2 S. The magnetic material showed high magnetism and brilliant electrocatalysis towards the electrochemical reduction of antibiotic nitrofurazone (NFZ). By utilizing screen-printed electrode (SPE) and HMNPs/S,N-CNSs, a disposable electrochemical NFZ sensor (HMNPs/S,N-CNSs/SPE) was fabricated by magnetic control. The current signal of NFZ at HMNPs/S,N-CNSs was 6.38 times higher than that of bare SPE. It displayed a wide detection range of 0.01–50 μM with a detection limit of 4.2 nM (S/N = 3). The practical applicability of the sensor in real samples presented satisfactory results. The disposability, low cost, high sensitivity, low consumption volume in analyses, and good selectivity make the proposed sensor a promising tool for NFZ detection.
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高影响因子
Journal of Materials Chemistry A
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2026
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IF 9.5
Qing Cheng,Yuqi Zhang,Yingying Cao,Long Liu,Yanqiang Zhang
The novel ionic liquid-H2O2 propellants are urgently to solve the intrinsic ignition problem for achieving the aerospace applications. We addressed this issue by tuning the d-band center to adjust the catalyst's adsorption strength for IL/H2O2 toward the optimal value, thus enhancing catalytic activities for the efficient decomposition of H2O2 to generate reactive oxygen species. Herein, the regulation of the d-band center of Cu(I) in Cu(I)-MOF catalyst by precise ligand engineering design was studied. Remarkably, The Cu-S3 coordination of Cu-SH' shifts its d-band center closer to the Fermi level, promoting the adsorption of [BMIM]N(CN)2 and H2O2. Cu-SH' enables efficient H2O2 activation and robust •OH and 1 O2 generation to trigger the rapid self-ignition of [BMIM]N(CN)2-H2O2 propellant. The resulted tid as low as 18.4 ms is nearly 34% lower than that of homogeneous catalyst [FcCH2N(CH3)3]2[Cu2I4]. This work provides fundamental insights into the design of efficient ligand-based combustion catalysts for the higher performance of rockets and spacecrafts.
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高影响因子
FUEL
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2026
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IF 7.5
Muhammad Kashif Majeed,Rashid Iqbal,M.Umar Majeed,Muhammad Akram,M.Zeeshan Ashfaq,Adil Saleem
Heterogeneous catalysis is highly desirable for the self-condensation of cyclohexanone, an important step in producing intermediates for fine chemicals and polymers. Conventional methods often rely on toxic reagents and long reaction times, limiting their industrial viability. In this study, Zr- and Hf-based metal–organic frameworks (UiO-66 and NUS-6) were developed as efficient, environmentally friendly catalysts for the self-condensation of cyclohexanone. Their high surface area and hierarchical porosity, combined with bifunctional Brønsted and Lewis acid sites introduced through partial linker substitution, enable excellent catalytic performance. UiO-66(Zr) achieved 81 % conversion in 6 h and 98 % in 48 h, while NUS-6(Zr) reached 85 % and 86 % under the same conditions, with high selectivity toward the desired dimer products. The catalysts also showed strong thermal stability and reusability, maintaining activity at elevated temperatures. This work demonstrates a sustainable catalytic pathway for cyclohexanone dimerization, avoiding corrosive chemicals while offering both efficiency and selectivity.
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DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2026
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IF 4.1
Zhou Hongtao,Sun He,Zhang Zebin,Fang Xin,Bu Shengjun,Li Chenxi,Wan Yue,Li Nan,Hao Zhuo,Ma Chengyou,Lv Na,Wan Jiayu
This study presents a signal-amplified detection platform integrating magnetic separation, PtAuRu@PCN-224 nano-enzyme catalysis magnification, and smartphone RGB analysis. The developed detection system has the following advantages: ultra-high sensitivity, the detection limit in ultraviolet-visible light mode is 1 CFU/mL; it features rapid response and excellent selectivity, capable of distinguishing common foodborne pathogenic bacteria; the nanozyme exhibits excellent stability, with its activity remaining above 92% after being stored at 4℃ for 10 days; the recovery rates in four food samples were 98 to 103%; and the relative standard deviations were less than 3%. This platform combines the high catalytic performance of MOFs nano-enzymes with the convenience of RGB analysis on smartphones, providing a new solution for the detection of foodborne pathogens. Graphical abstract
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DOI
PubMed
高影响因子
DALTON TRANSACTIONS
·
2017
·Vol. 46
·期 23
·7412-7420
·
IF 4.029
Zhe Wang,Ying Huang,Jian Yang,Yongsheng Li,Qixin Zhuang,Jinlou Gu
The primary pollutant, radioactive iodine (I2), has become a worldwide concern due to its serious ill effects of radiotoxicity on human health. Therefore, it is of great significance to develop novel adsorbents for effectively eliminating I2 from nuclear waste. Herein, we reported a Zr-based MOF adsorbent constructed by utilizing pyridine-containing pyridine-dicarboxylic acid (PYDC) as organic ligands (UiO-66-PYDC) as well as active sites for the efficient removal of I2. UiO-66-PYDC MOFs were synthesized by a hydrothermal strategy and featured good chemical and thermal stabilities, endowing them with the ability to work in harsh environments. The abundant and inherent pyridine moieties in the developed adsorbent worked as active adsorption sites to capture I2. The correlation between the most significant parameters such as the contact time, adsorbate concentration, and reusability was optimized, and the interaction mechanism between I2 and UiO-66-PYDC was investigated in detail. As for the current adsorbent, a pseudo-second order rate equation was used to explain the removal kinetics, and the Langmuir model exhibited a better fit to the adsorption isotherm than the Freundlich model. Thanks to the strong affinity of PYDC ligands to I2 and high porosity, the adsorption capacities of UiO-66-PYDC for I2 could reach as high as 1250 mg g−1, which was much higher than those of many other reported MOFs. Additionally, the UiO-66-PYDC MOFs exhibited excellent renewable adsorption properties, prefiguring their great promise as green adsorbents for I2 removal in nuclear waste management.
研究领域:
环境科学
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材料化学
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核废物处理
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吸附科学
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功能材料
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DOI
高影响因子
Nano Energy
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2016
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IF 11.553
Zhaoqiang Li,Caixia Li,Xiaoli Ge,Jingyun Ma,Zhiwei Zhang,Qun Li,Chengxiang Wang,Longwei Yin
Reduced graphene oxide (RGO) wrapped metal-organic frameworks (MOFs) derived cobalt doped porous carbon polyhedrons synthesized via a carbonization process, are for the first time used for sulfur immobilizers (RGO/C–Co-S) as cathodes for high performance lithium-sulfur (Li–S) batteries. The RGO/C–Co–S cathode exhibits greatly improved electrochemical performance, showing excellent specific capacity of 949 mAh g −1 at 300th cycle at a current density 0.3 A g −1 , displaying enhanced rate capability with specific capacity of 772, 704 and 606 mAh g −1 at current density of 0.5, 1 and 2 A g −1 , respectively. The synergetic effect of MOFs-derived porous carbon, homogeneously distributed Co nanoparticles and RGO nanosheets simultaneously contributes to the confinement of sulfur species. The presence of abundant mesopores and micropores is conducive to immobilize large amounts of S species. The homogenously inlaid ultrafine Co nanoparticles can further immobilize sulfur by chemical interactions between Co and S/polysulfides. The RGO nanosheets tightly wrapped on carbon hosts act as barrier layers to prevent polysulfides from diffusing out of the matrix, further suppressing shuttle effect. The porous structure and the RGO can effectively alleviate the volume changes resulted from charge–discharge process. This design strategy can be inspiring for MOF-derived materials in energy storage applications .
研究领域:
材料科学
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电化学
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能源存储
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纳米材料
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电池技术
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DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2022
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IF 7.968
Qinglian Sun,Sheng Huang,Zaoyuan Li,Donghua Su,Jinfei Sun
Metal-organic frameworks (MOFs) effectively remove hazardous contaminants and are widely used for wastewater treatment . In this work, Co-doped bimetallic MIL-88B(Fe/Co) was synthesized via the hydrothermal method to activate potassium persulfate (KPS) for methylene blue (MB) degradation. XRD , IR, XPS, and SEM were conducted to investigate the crystalline structure, chemical valence state, and morphology of MIL-88B(Fe/Co). The synthesis time and Fe 3 + /Co 2 + molar ratio were optimized. Results showed that 10% Co-doped MIL-88B(Fe/Co) could efficiently activate KPS to achieve 100% MB removal in 15 min, thereby indicating that Co 2 + could accelerate metal-to-metal charge transfer during activation. A quadratic model was established by fitting the experimental data to optimize the degradation parameters. The reaction system with a temperature of 70 °C, KPS concentration of 30 mM, MOFs concentration of 0.8 g/L, and initial pH of 10 could effectively remove 99.85% MB in 5 min. Quenching experiments and EPR analysis revealed that·OH, 1 O 2 , and·O 2 − were the dominant reactive oxygen species (ROS) during MB degradation. The active sites (N15, N7, S10, and N18) most vulnerable to ROS attack in MB were identified by DFT calculation. MB degradation intermediates were identified through MALDI.
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