Sensing and Bio-Sensing Research
·
2025
·
IF 4.9
Xiaohua Jiang,Zhiwen Lv,Changquan Rao,Xiaowen Chen
Foodborne pathogenic bacteria pose severe threats to human health and often coexist within the same environment. Thus, developing a sensitive and reliable method for their simultaneous detection is critically important. In this study, we first synthesized Ti 3 C 2 T x MXene nanoribbons/copper nanoparticles (Ti 3 C 2 T x NR/Cu) via a simple self-reduction method to modify electrodes for signal amplification. Concurrently, we constructed UiO-66 MOFs encapsulated with distinct probes and gated by target-specific aptamers (Apts) as bio-gatekeepers. We then proposed an innovative electrochemical strategy for the simultaneous detection of two model pathogens: Staphylococcus aureus ( S. aureus ) and Listeria monocytogenes (LM). The Ti 3 C 2 T x NR/Cu nanohybrid synergistically enhanced the current signals of the probes by leveraging the combined advantages of Ti 3 C 2 T x NR and Cu nanoparticles. For S. aureus detection, methylene blue (MB) and S. aureus -specific aptamer (S-Apt) were employed as the probe and bio-gatekeeper, respectively, while ferrocene (Fc) and LM-specific aptamer (L-Apt) were used for LM. Upon target binding, the Apts dissociated from the UiO-66 MOFs, releasing the encapsulated probes (MB or Fc). The resulting current signals, measured at the Ti 3 C 2 T x NR/Cu electrode, enabled the quantitative and simultaneous detection of both pathogens. This platform's modular design allows easy adaptation for detecting other bacteria by simply replacing the aptamers, offering broad potential applications in controlling food safety.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Fahang Xu,Qianqian Zhang,Rushun An,Ling Li,Limin Zhou
A novel Z-scheme 3D flower-like NH 2 -UIO-66/BiOCl composite was fabricated by a facile solvothermal method. The structural characterization results demonstrate that NH 2 -UIO-66 is embedded on the smooth surface of the flower-like BiOCl, forming a tight contact interface. As a visible light collector, NH 2 -UIO-66 expands the optical absorption range of BiOCl, which is confirmed by the UV-Vis diffuse reflectance spectra (DRS). By combining UV-Vis DRS, Mott-Schottky (MS) plots and VB-XPS, a well-matched band structure between NH 2 -UIO-66 and BiOCl is obtained. Photoelectrochemical characterizations indicate that the synergistic effect between NH 2 -UIO-66 and BiOCl interfaces facilitates the separation and transfer of photogenerated electron-hole pairs. In the case of photocatalytic performance experiments, the removal efficiency of the prepared NU66/BOC composites for TC-HCl was higher than either NH 2 -UIO-66 or BiOCl under simulated solar irradiation. NU66/BOC-20 exhibited the best performance with K app value (0.01269 min −1 ), which is 84 and 3 times more than the pristine NH 2 -UIO-66 (0.00015 min −1 ) and BiOCl (0.00410 min −1 ), respectively. In addition, NU66/BOC-20 composite demonstrates remarkable stability with a TC-HCl removal rate of 83% in the third cycle. The radical quenching experiments indicate that the primary active species is superoxide radicals (·O 2 − ) while holes (h + ) play a role to some extent. Based on the above experimental results and in-situ irradiated XPS , Z-scheme was proposed to explain the electron transfer pathway in the photocatalytic process.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Qunfeng Chen,Daobin Tang,Qi Zhang,Zhiyuan Tang,Longlong Ma,Xinghua Zhang
Electron-metal support interactions (EMSI), which can tailor the microenvironment through electron transfer and coordination structure design, are an effective strategy to augment the intrinsic catalytic activity of catalysts. However, it remains challenging to establish the interfacial structure and interfacial electron configuration of catalysts to precisely regulate and enhance EMSI. In this work, the spatially defective sites and specific electronic states of Pd-UiO-66 were modified by in-situ constructing a W-O-Zr interface to strengthen the EMSI between Pd nanoparticles (Pd NPs) and UiO-66 support via implanting W into the defective Pd-UiO-66, realizing the effective hydrodeoxygenation (HDO) of vanillin (VAN) at room temperature (RT). The as-prepared catalyst Pd-UiO-66–0.24 W achieved > 99 % conversion of VAN and > 99 % yield of 2-methoxy-4-methylphenol (MMP) within 12 h, which surpassed the previous reports. The DFT analysis revealed that the narrow band-gap energy between Pd-UiO-66–0.24 W and H 2 molecule, along with the σ or π coordination adsorption between p and d orbitals of the implanted W and O in C=O, facilitated the activation of the H 2 molecules and reactant molecules. In addition, the constructed electron-deficient W-O-Zr interfacial sites provided more acidic sites that favor the cleavage of C-O bonds, promoting the HDO process of VAN. This work provides important insights into the modulation of EMSI, structural defects and acidic sites of metal–organic frameworks (MOFs)-based catalysts for efficient HDO of lignin-derived oxygenated compounds.
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Journal of Materials Chemistry B
·
2021
·Vol. 9
·期 43
·9031-9040
·
IF 6.331
Jilin Zheng,Peng Zhao,Shiying Zhou,Sha Chen,Yi Liang,Fengchun Tian,Jun Zhou,Danqun Huo,Changjun Hou
Integrating metal–organic frameworks (MOFs) of different components or structures together and exploiting them as electrochemical sensors for electrochemical sensing has aroused great interest. Furthermore, the incorporation of noble metals with MOFs is conducive to the improvement of catalytic performance. In this work, Pd@UiO-66-on-ZIF-L nanomaterials were successfully synthesised onto a self-supported flexible carbon cloth (Pd@UiO-66-on-ZIF-L/CC) through a novel strategy called MOF-on-MOF. Then, Au nanoparticles were electrodeposited onto Pd@UiO-66-on-ZIF-L/CC to obtain Au–Pd@UiO-66-on-ZIF-L/CC, which can serve as an excellent electrocatalyst for the reduction of hydrogen peroxide (H2O2). The obtained flower-like Pd@UiO-66-on-ZIF-L/CC hybrid MOF changes the structure of the monomeric MOF alone and adds more attachment sites. The synergy of the bimetals greatly improved the catalytic performance of the as-developed sensor. Electrochemical experiment results show that the proposed sensor based on Au–Pd@UiO-66-on-ZIF-L/CC has an extended linear range from 1 μM to 19.6 mM with a sensitivity of 390 μA mM−1 cm−2, and a low limit of detection (LOD) of 21.2 nM (S/N = 3). Moreover, it has good anti-interference, reproducibility, repeatability and excellent stability. Furthermore, the real-time in situ detection of H2O2 secreted from human adenocarcinomic alveolar basal epithelial cells (A549 cells) was achieved by culturing cells on Au–Pd@UiO-66-on-ZIF-L/CC, which indicates the potential of the sensor for applications in cancer pathology. Both the synthesis strategy and the sensor design provide new methods and ideas for the production of ultrasensitive H2O2 electrochemical sensors.
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高影响因子
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
·
2025
·
IF 3.8
Kaiqiang Wang,Xiaoyan Duan,Ye Tian,Hong Lin,Limin Cao,Jianxin Sui
In this work, a novel method for sensitive detecting heavy metal Pb (II) in aquatic products was developed using UiO-66-NH 2 @tannic acid (UiO-66-NH 2 @TA) solid-phase extraction combined with laser-induced breakdown spectroscopy (LIBS). UiO-66-NH 2 @TA adsorbent could effectively extract Pb (II) from the digestive solution of aquatic products. Characterization of the morphology of the adsorbent was performed using transmission electron microscopy and scanning electron microscopy. The optimal experimental conditions for LIBS detection, including sample preparation, substrate type, laser energy, and delay time, were investigated. The results showed that the strongest Pb I 405.7 nm spectral signal can be obtained by dripping UiO-66-NH 2 @TA adsorbent onto a silicon wafer for LIBS testing. The limit of detection and limit of quantification for Pb (II) in aqueous solution were 0.18 μg/mL and 0.61 μg/mL, respectively. The calibration curve demonstrated good sensitivity and accuracy for Pb (II) detection with a correlation coefficient of 0.9905. Spiked recovery experiments on large yellow croakers and scallops yielded recovery rates of 75.25 % - 99.08 %, which was consistent with the results from atomic absorption spectrometry. This study underscores the potential of the solid-phase extraction combined with laser-induced breakdown spectroscopy for practical application in food safety monitoring, demonstrating its effectiveness and reliability in detecting Pb (II) in aquatic products.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Haojie Zeng,Qi Wang,Dingyu Xing,Jiajia Yuan,Feiyun Sun
To solve the freshwater dilemma, photothermal membrane distillation (PMD) has become a promising and sustainable method for desalination and wastewater purification. Ti 3 C 2 T x has attracted much attention in the field of Janus PMD membrane preparation due to its hydrophilic surface and high photothermal conversion efficiency. However, the shortcomings of easy stacking and surface light reflection limit its application. In this work, electrostatic adsorption self-assembly between Ti 3 C 2 T x and UiO-66-NH 2 by pH adjusting is designed, and the Ag-modified Ti 3 C 2 T x aims to significantly improve the photothermal conversion efficiency-Ag@Ti 3 C 2 T x /UiO-66-NH 2 membrane. Compared to the origin Ti 3 C 2 T x membrane, the photothermal layer containing UiO-66-NH 2 contributes to the unimpeded transport of water, and this 3D photothermal layer structure can maximize the capture and absorption of light, which contributes to enhanced high light absorption, photothermal conversion ability and more efficient mass transfer. Thus, a consistently high vapor flux of 1.13 kg/m 2 h and photothermal efficiency over 77.3 % were synchronously obtained, under one solar irradiation. Specifically, Ag@Ti 3 C 2 T x /UiO-66-NH 2 membrane meanwhile exhibits commendable water permeate production and high stability in anti-scaling tests, as well as reliable physical stability, which offers great application potential in PMD process. Our work provides a novel strategy for constructing PMD membrane with stably enhanced mass transfer and photothermal properties to satisfy real application.
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APPLIED ORGANOMETALLIC CHEMISTRY
·
2026
·Vol. 40
·期 4
·e70546
·
IF 4.3
Hangyu Zhang,Shuang Yao,Zhiwen Jiang,Lei Xie,Zixia Lin,Guoliang Dai,Juanhong Li,Xin Liu,Feng Liu
In Fenton-like reactions, the catalysts generally have an inherent drawback: Their active centers are prone to being lost from the catalyst supports, leading to a continuous decline in catalytic efficiency and causing secondary pollution. To address this issue, two catalysts, including Fe 3 O 4 @UiO-66(Zr) and Fe 3 O 4 @UiO-66(Zr)-COOH, were prepared in this study by confining Fe 3 O 4 active centers within the pores of UiO-66(Zr) and grafting -COOH groups to enhance metal coordination interactions. The Fe 3 O 4 @UiO-66(Zr)-COOH achieved 99% removal efficiency of carbamazepine within 5 min under the conditions of pH = 3.0, 40 mM H 2 O 2 , 20 mg·L −1 carbamazepine, and 2 g·L −1 catalyst. This efficiency far exceeded that of Fe 3 O 4 @UiO-66(Zr) (61.5%) and was 3.96 times higher than that of the Fenton-like system. The rapid degradation of CBZ was realized through stabilized active centers and enhanced metal coordination. In this work, the iron-based material was found to enhance the coordination between Fe and Zr. As confirmed by quenching experiments, electron spin resonance, electrochemical tests, and density functional theory calculations, ·OH and 1 O 2 were identified as the dominant active species. The -COOH, acting as electron bridges, enhanced electrical conductivity and reduced electron transfer barriers, thereby facilitating faster charge transfer processes. In addition, it was demonstrated by six cycles of experiments that Fe 3 O 4 @UiO-66(Zr)-COOH possessed excellent stability. It was also shown by the characterization of the catalyst after the cycles that both the performance and morphology of the composite material could be maintained unchanged.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Fan Xiao,Ming Cao,Yingbo Chen,Xiaofeng Lin
Oil-contaminated wastewater, a pervasive byproduct of industrial processes, poses severe ecological threats, particularly surfactant-stabilized emulsions (SSEs) with high dispersion stability and resistance to conventional separation. Addressing this challenge demands innovative materials with superior separation efficacy. Electrospun nanofiber membranes, though promising, are often limited by low flux and poor durability. To address the issues, we presented an amidoxime functionalized UiO-66 (UiO-66-AO) mediated polyacrylonitrile (PAN) composite nanofiber membrane fabricated through a novel coaxial two-component electrospinning coupled with sacrificial template strategy. The membrane design utilized UiO-66-AO/PAN served as the shell-layer matrix, with polyvinylpyrrolidone (PVP) as a sacrificial core template. Subsequent the dissolution of PVP template created longitudinally aligned hollow groove structure, introducing rough surface while preserving structural integrity. Amidoxime modification enhanced the dispersion compatibility of UiO-66-AO within the PAN matrix, further improving the superhydrophilicity and implementing multi-level micro-nano rough structure of composite nanofibers. The synergistic effect of PVP template and UiO-66-AO promoted the generation of AO/PAN membranes with high separation area, excellent water-wetting property, and underwater superoleophobicity. The optimized 0.5 % AO/PAN composite membrane delivered outstanding separation performance for different SSEs, achieving high flux of 9689.7 L·m −2 ·h −1 and good separation efficiency of 99.4 % for petroleum ether/water SSE. Remarkably, after 20 separation cycles for n-hexane/water SSE, 0.5 % AO/PAN retained the flux recovery capability of 84.44 %, demonstrating superior anti-fouling capability and long-term durability. This work provides a robust strategy for fabricating high-performance nanofiber membranes through precise microstructure engineering and functional group modification, offering a promising solution for the treatment of challenging oily wastewater.
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Polymers
·
2025
·Vol. 17
·期 21
·2879
·
IF 4.9
Guifang Yang,Qiu Wu,Gao Xiao,Xiaoxia Ye
Membrane separation is a promising technology for emulsified wastewater treatment. However, conventional membrane often suffer from limitations such as low mechanical strength, the inherent “trade-off” effect between flux and separation efficiency, and poor antifouling properties. To address these challenges, we report a novel composite membrane (CFM-UiO-66-(COOH)2) fabricated by in situ growth of functionalized UiO-66-(COOH)2on a mechanically robust collagen fiber membrane (CFM) substrate. The resulting composite leverages the inherent properties of the CFM, along with the controlled generation of charge-neutralization demulsification sites and size-sieving filtration layers from the UiO-66-(COOH)2. This CFM-UiO-66-(COOH)2exhibited superwetting behavior and achieved efficient separation of cationic surfactant-stabilized oil-in-water micro- and nano-emulsions. Specifically, the CFM-UiO-66-(COOH)2achieved separation efficiencies exceeding 99.85% for various cationic O/W emulsions, with permeation fluxes ranging from 178.9 to 225.9 L·m−2·h−1. The membrane also demonstrated robust antifouling properties, excellent acid/alkali resistance, high abrasion durability, and good biocompatibility. Importantly, stable performance was maintained over six consecutive separation cycles. These characteristics, combined with the electrostatic interactions between carboxyl groups on the UiO-66-(COOH)2and cationic contaminants, suggest that CFM-UiO-66-(COOH)2holds significant potential for practical and sustainable wastewater treatment applications.
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高影响因子
Frontiers in Microbiology
·
2026
·
IF 5.8
Xiangting Li,Meng Ren,Shuhang Deng,Lingli Lei,Ping Ma,Yingshuai Liu
IntroductionPotato virus S (PVS) causes severe damage to Solanaceae plants, especially potato, due to its widespread infection and the reliance on laboratory-based reverse transcription-polymerase chain reaction (RT-PCR) testing. This work intends to develop a rapid, highly sensitive, and dual-signal platform for on-site PVS detection.MethodsWe developed a highly sensitive lateral-flow immunoassay (LFIA) capable of colorimetric and fluorescent dual-mode detection based on a novel core-shell structured probe, which consists of a porous metal-organic framework UiO-66 encapsulating rhodamine B inside and loading gold nanoparticles (AuNPs) outside with 3-aminopropyltriethoxysilane (APTES) as a spacer and glue, denoted as UR@APTES@AuNPs.ResultsThe developed LFIA enabled dual-mode PVS detection within 15 min with negligible cross-interference from Potato virus X and Potato virus Y. The platform achieved a limit of detection (LOD) of 31.2 pg/mL for the colorimetric mode and 7.6 pg/mL for the fluorescent mode, over one order of magnitude lower than the conventional AuNPs-based LFIA (LOD = 462.4 pg/mL). Furthermore, PVS in field-collected potato leaves was successfully detected by the new LFIA platform.DiscussionThe dual-mode LFIA demonstrated a rapid, cost-effective, and highly sensitive on-site screening of PVS in field samples, highlighting its great potential in practical application. This platform can be easily adapted to the detection of other pathogenic viruses by using the corresponding specific antibodies.
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MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 3
·1-10
·
IF 6.408
Xu Yaxin,Li Peipei,Zhu Yu,Tang Ying,Chen Haoyu,Zhu Xiaohua,Wu Cuiyan,Zhang Youyu,Liu Meiling,Yao Shouzhuo
A novel nanocomposite of CuO nanoparticle-modified Zr-MOF (CuO/UiO-66) was synthesized and developed as a fluorescence nanoplatform for H 2 O 2 and adenosine triphosphate (ATP) via the “turn-on–off” mode in the presence of terephthalic acid (TA). The structure of CuO/UiO-66 was thoroughly characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), and other techniques. The CuO/UiO-66 with enhanced peroxidase-like (POD) activity obtained due to the Zr 4+ in UiO-66 is beneficial to the aggregation of CuO NPs on its surface. As a result, the strengthened fluorescence at 425 nm with the excitation of 300 nm was found due to the highly fluorescent species of TAOH. This is produced by the oxidation of TA by ·OH that came from the catalysis of H 2 O 2 via the peroxidase mimic of CuO/UiO-66. Hence the modification of CuO NPs on porous UiO-66 can provide a friendly and sensitive physiological condition for H 2 O 2 detection. However, upon addition of ATP, the fluorescence intensity of TAOH at 425 nm effectively declined owing to the formation of complexation of Zr 4+ -ATP and the interaction of CuO to ATP which hampers the catalytic reaction of CuO/UiO-66 to H 2 O 2 . The specific interaction induced “inhibition of the peroxide-like activity” endows the sensitive and selective recognition of ATP. The detection limits were 16.87 ± 0.2 nM and 0.82 ± 0.1 nM, and linear analytical ranges were 0.02–100 μM and 0.002–30 μM for H 2 O 2 and ATP, respectively. The novel strategy was successfully applied to H 2 O 2 and ATP determination in serum samples with recoveries of 97.2–103.8% for H 2 O 2 and 97.6–101.7% for ATP, enriching the avenue to design functional MOFs and providing new avenue of multicomponent bioanalysis. Graphical abstract
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Zhiwen Li,Wentian Zhang,Min Tao,Liguo Shen,Renjie Li,Meijia Zhang,Yang Jiao,Huachang Hong,Yanchao Xu,Hongjun Lin
In-situ growth of UiO-66-NH 2 in ordinary porous polymeric substrates offers promising opportunities to eliminate interfacial defects in mixed matrix membranes (MMMs). However, this strategy is still hard to be realized because conventional hydrothermal synthesis of UiO-66-NH 2 involves harsh conditions (e.g., high temperatures, and polar aprotic solvents), which are destructive to ordinary polymer. Herein, UiO-66-NH 2 was in-situ grown in polymeric substrates under room temperature via a successive immersion of a porous polyether sulfones substrate in a Zr 4+ formic acid/ethanol solution and a 2-aminoterephthalic acid ethanol/formic acid/water solution. Attenuated total refraction Fourier transform infrared and X-ray diffraction characterizations demonstrated the successful incorporation of UiO-66-NH 2 in the substrate. The optimized membrane possessed a high pure water permeance of 209.5 L -2 h −1 bar −1 and rejections higher than 99.5% towards small molecules of Congo Red, xylene brilliant cyanin G, and Rose Bengal sodium salt. More importantly, after a 5-day immersion in water or an intense ultrasonication treatment, the membrane showed no significant change in separation performance, suggesting its excellent stability. The novel strategy regarding MMMs with UiO-66-NH 2 in-situ growth disclosed in this study paves the way to develop advanced UiO-66-NH 2 membranes toward sustainable molecular separation in environmental applications.
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