RSC Advances
·
2016
·Vol. 6
·期 103
·100891-100898
·
IF 3.289
Kun Peng,Qiqin Wang,Weijia Chen,Donghai Xia,Zhengyin Zhou,Yuqiang Wang,Zhengjin Jiang,Fuhai Wu
A novel phosphatidic acid functionalized polymeric monolithic column was prepared through the thermally initiated co-polymerization of 12-methacryloyl dodecylphosphatidic acid (MDPA) and ethylene glycol dimethacrylate (EDMA) in the presence of 1,4-butanediol and isopropanol as porogens within 100 μm I.D. capillaries. The polymerization conditions of monolithic columns were systematically optimized in order to obtain good permeability, stability and column efficiency. The reproducibility of the optimized monolithic column was also satisfactory. The physicochemical properties of the monolithic column were evaluated by use of instrumental techniques including scanning electron microscopy, Fourier transform infrared spectra, ζ-potential analysis and micro-HPLC. A series of test compounds such as small peptides, alkylphenones, etc., were employed to investigate the retention mechanism on the poly(MDPA-co-EDMA) monolithic column. The results demonstrate that both hydrophobic and cation-exchange interactions could contribute to the overall retention of analytes. Furthermore, the novel reversed-phase/cation-exchange mixed mode monolithic column was applied to the separations of small peptides, phenols, water-soluble vitamins B, and pharmaceutical compounds. The successful applications indicate the potential of the poly(MDPA-co-EDMA) monolithic column in complex sample analysis.
✓ 已验证
产品关联
DOI
高影响因子
CARBON
·
2017
·
IF 6.337
Fangzhou Li,Yun Wang,Zhipeng Zhang,Yuanyuan Shen,Shengrong Guo
It is still a tremendous challenge to combat multidrug resistant (MDR) cancer up to now, due to cancer resistance to chemotherapeutic agents. Herein, we put a new strategy for effective treatment of MDR cancer by improving chemotherapeutic efficacy via chemosensitizer in combination with phototherapy. Our previous work has demonstrated poly (ethylene glycol) - poly (curcumin-dithiodipropionic acid) (PEG-PCDA) is a good pre-chemosensitizer and enhances the sensitivity of MDR cancer cells to doxorubicin (DOX). In this study, we firstly synthesized mesoporous carbon nanoparticles (MCNs) having excellent photothermal and photodynamic effects, which could load a high dose of hydrophobic drug and presented pH -responsive drug release characteristics. On this basis, we developed a multifunctional MCN based drug delivery system to take chemo/photo- co-therapy against MDR human breast cancer MCF-7/ADR cells. The MCN based drug delivery system loaded 36.4% DOX and was coated with 23.2% PEG-PCDA, which could take photothermal and photodynamic effects under near-infrared (NIR) irradiation and trigger drug release by pH, glutathione (GSH), and/or NIR irradiation, termed as PEG-PCDA/DOX@MCNs. Once the PEG-PCDA/DOX@MCNs had been delivered into MCF-7/ADR cells, DOX release was triggered by degradation of PEG-PCDA via GSH and weak acidic pH, and in combination with MCN yielded photothermal and photodynamic effects under NIR irradiation, PEG-PCDA/DOX@MCNs could reduce premature drug release and then enhance anti-MDR cancer efficacy.
✓ 已验证
产品关联
DOI
高影响因子
WATER RESEARCH
·
2017
·
IF 6.942
Guangsen Xia,Yujue Wang,Bin Wang,Jun Huang,Shubo Deng,Gang Yu
Previous studies indicate that effective generation of hydrogen peroxide (H 2 O 2 ) from cathodic oxygen (O 2 ) reduction is critical for the improved water treatment performance (e.g., enhanced pollutant degradation and reduced bromate formation) during the electro-peroxone (E-peroxone) process (a combined process of electrolysis and ozonation). However, undesired reactions (e.g., O 3 , H 2 O 2 , and H 2 O reductions) may occur in competition with O 2 reduction at the cathode. To get a better understanding of how these side reactions would affect the process, this study investigated the cathodic reaction mechanisms during electrolysis with O 2 /O 3 gas mixture sparging using various electrochemical techniques (e.g., linear sweep voltammetry and stepped-current chronopotentiometry). Results show that when a carbon brush cathode was used during electrolysis with O 2 /O 3 sparging, H 2 O and H 2 O 2 reductions were usually negligible cathodic reactions. However, O 3 can be preferentially reduced at much more positive potentials (ca. 0.9 V vs. SCE) than O 2 (ca. −0.1 V vs. SCE) at the carbon cathode. Therefore, cathodic O 2 reduction was inhibited when the process was operated under current limited conditions for cathodic O 3 reduction. The inhibition of O 2 reduction prevented the desired E-peroxone process (cathodic O 2 reduction to H 2 O 2 and ensuing reaction of H 2 O 2 with O 3 to OH) from occurring. In contrast, when cathodic O 3 reduction was limited by O 3 mass transfer to the cathode, cathodic O 2 reduction to H 2 O 2 could occur, thus enabling the E-peroxone process to enhance pollutant degradation and mineralization. Many process and water parameters (applied current, ozone dose, and reactivity of water constituents with O 3 ) can cause fundamental changes in the cathodic reaction mechanisms, thus profoundly influencing water treatment performance during the E-peroxone process. To exploit the benefits of H 2 O 2 in water treatment, reaction conditions should be carefully controlled to promote cathodic O 2 reduction during the E-peroxone process.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CATALYSIS COMMUNICATIONS
·
2017
·
IF 3.33
Junyi Liu,Hua Huang,Xianxiang Liu,Jiafu Xiao,Sheng Zhong,Xichun She,Zaihui Fu,Steven Robert Kirk,Dulin Yin
A series of Fe 2 O 3 doped SBA-15 materials were prepared via an equivalent-volume impregnation method. The resultant Fe 2 O 3 -containing SBA-15 materials showed good performance in phenol methylation . Under the same conditions, the mesoporous catalyst with 5 wt.% Fe 2 O 3 showed the superior catalytic activity to that of pristine α -Fe 2 O 3 even at lower reaction temperature (320 °C vs. 350 °C). The elevated catalytic activity observed for the mesoporous catalyst could be due to high level dispersion of Fe 2 O 3 species in the mesoporous framework. Furthermore, the mesoporous catalyst possessed long lifetimes, which could be used continuously for 2000 h without significant loss of activity.
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 94
·91659-91668
·
IF 3.289
Yanli Mao,Minjia Meng,Li Yan,Fengquan Sun,Yongsheng Yan,Shijuan Liu
Herein, highly selective molecularly imprinted membranes (MIM) for methyl salicylate (MS) are synthesized with 4-vinylpyridine (4-VP), acrylamide (AM) or methacrylic acid (MAA) as the functional monomer based on the Al2O3 microporous ceramic membrane. Fast kinetic equilibrium for the rebinding of MS was found on all the imprinted membranes. Compared with AM-MIM and MAA-MIM, 4-VP-MIM presents a stronger adsorption capacity and higher permeation selectivity for MS due to the formation of ionic bonds between MS and 4-VP. SEM analysis shows that the surface morphology of the membranes is strongly influenced by the concentration of vinyltrimethoxysilane. Compared with 4-VP-MIM (1, 2 or 4), 4-VP-MIM3 possesses higher kinetic equilibrium adsorption, binding capacity and better selectivity for MS. It was found that the pseudo-second-order kinetic model is suited to describe the kinetic of 4-VP-MIM3, as determined by multiple regression analysis. The adsorption isotherm analysis exhibits that 4-VP-MIM3 has the maximum adsorption capacity for MS. Moreover, the selectivity experiment shows that the selectivity coefficients of 4-VP-MIM3 for MS relative to salicylic acid (SA) and phenol are 2.4185 and 2.2277, respectively, which are close to the predicted selectivity coefficient values.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2017
·Vol. 134
·期 43
·45444
·
IF 1.86
Fuchen Zhang,Qiuxia Wang,Lipeng Wang,Yongping Bai
This article describes the implementation of plant-derived isosorbide (IS) and isomannide (IM) in the copolymerization modification of poly(ethylene terephthalate). The effects of the two comonomers on the optical, crystallization, and thermal properties of the resulting copolyesters were studied using the following analytical methods: proton nuclear magnetic resonance; differential scanning calorimetry; X-ray diffraction; thermogravimetry; and ultraviolet-visible spectroscopy. As comonomers, IS and IM increased the transmittance and reduced the haze of the copolyesters. Moreover, while IM improved the optical properties more than did IS, both monomers improved the optical properties of the copolyesters by lowering its crystallization ability. After the copolymerization modification, the crystallization rate of the copolyesters was reduced, decreasing the crystallinity and crystal size and thereby reducing the light transmission interference. The comonomers also altered the light absorption properties of the copolyesters and conferred a substantial increase in the transmittance of near-infrared (NIR) wavelengths. These changes in optical properties exhibit the potential of these comonomers for applications in optical materials and NIR detectors. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 45444.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry A
·
2017
·Vol. 5
·期 34
·18071-18080
·
IF 8.867
Zhigao Zhu,Chenghan Ji,Lingling Zhong,Shuang Liu,Fuyi Cui,Hongliang Sun,Wei Wang
Porous carbonaceous materials are widely used as catalyst carriers to activate peroxymonosulfate (PMS) for catalytic oxidative degradation of organic pollutants. Herein, hierarchical structured ferro-cobalt alloyed crystals supported on nitrogen doped activated porous carbon fibers (FeCo2@APCFs) were prepared by a combination of multicomponent electrospinning, activation, and carbonization. Benefiting from the precursor design and activation process, the carbon fibers derived from a PAN/PBZ (polyacrylonitrile/polybenzoxazine) precursor exhibited a tunable porous structure with an ultrahigh specific surface area (SSA) and pore volume of 2085 m2 g−1 and 1.12 cm3 g−1, respectively. Most importantly, the FeCo2 crystals can be directly synthesized by carbonization at high temperature in a N2 flow with no other reducing gases. The as-prepared FeCo2@APCFs exhibited robust activation of PMS with reactive oxygen radicals (SO4˙−, ˙OH, and 1O2) for ultrafast removal of organic pollutants, as well as good stability and recyclability with high total organic carbon (TOC) removal. The catalyst suspended in aqueous solution after catalysis can be easily separated with an external magnet without tedious separation processes. This study is meaningful for the development of novel catalyst carriers or a fascinating strategy for wastewater treatment.
✓ 已验证
产品关联
DOI
高影响因子
ChemSusChem
·
2016
·Vol. 9
·期 19
·2759-2764
·
IF 7.116
Runyuan Ma,Liang Wang,Bingsen Zhang,Xianfeng Yi,Anmin Zheng,Feng Deng,Xuhua Yan,Shuxiang Pan,Xiao Wei,Kai-Xue Wang,Dang Sheng Su,Feng-Shou Xiao
Graphical Zirc-S maximus : A zirconium-doped anatase catalyst (S-Zr-TiO 2 ) is prepared. The catalyst features zirconium sites with Brønsted acidity uniformly distributed on the sub-10 nm anatase crystals. The S-Zr-TiO 2 catalyst exhibits high catalytic activity towards the degradation of phenol under visible-light illumination, owing to a synergistic effect of the Brønsted acidity and photoactivity. The preparation of photocatalysts with high activities under visible-light illumination is challenging. We report the rational design and construction of a zirconium-doped anatase catalyst (S-Zr-TiO 2 ) with Brønsted acidity and photoactivity as an efficient catalyst for the degradation of phenol under visible light. Electron microscopy images demonstrate that the zirconium sites are uniformly distributed on the sub-10 nm anatase crystals. UV-visible spectrometry indicates that the S-Zr-TiO 2 is a visible-light-responsive catalyst with narrower band gap than conventional anatase. Pyridine-adsorption infrared and acetone-adsorption 13 C NMR spectra confirm the presence of Brønsted acidic sites on the S-Zr-TiO 2 sample. Interestingly, the S-Zr-TiO 2 catalyst exhibits high catalytic activity in the degradation of phenol under visible-light illumination, owing to a synergistic effect of the Brønsted acidity and photoactivity. Importantly, the S-Zr-TiO 2 shows good recyclability.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2016
·
IF 4.035
Meng Li Liu,Bin Bin Chen,Ze Xi Liu,Cheng Zhi Huang
Though many methods of detecting 2,4,6-trinitrophenol (TNP) mainly have been developed recent years, quantification of TNP in environmental matrixes still faces up to great challenges because all the nitroaromatic explosives reveal highly similar chemical structure. In the present work, we have developed a selective and sensitive method for detection of TNP by amorphous photoluminescent carbon nanodots (CNDs), which are prepared through a simple hydrothermal route using spermine and m-phenylenediamine (MPD) as precursors. The as-prepared CNDs are found to show blue–green photoluminescence, excitation-wavelength independence, and excellent chemical and optical stability. Owing to the strong characteristic absorption of TNP at 356 nm ( ε =1.048×10 4 cm −1 M −1 ), which has a good spectral overlap with the excitation band of CNDs, the fluorescence intensity of CNDs at 490 nm is linearly quenched with the adding concentration of TNP in the range of 0.1–100 μM. The developing assay based on inner filter effect (IFE) mechanism for the detection of TNP is selective and convenient, showing that the as-prepared CNDs have applicable prospect in the concept of simplicity and specificity in analytical chemistry .
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FLUID PHASE EQUILIBRIA
·
2016
·
IF 1.846
Youan Ji,Yucui Hou,Shuhang Ren,Congfei Yao,Weize Wu
Phase equilibria of the binary systems of high pressure CO 2 + deep eutectic solvents (DESs) formed by quaternary ammonium salts (QASs, including 2-hydroxy- N , N , N -trimethyl-ethanaminium chloride, ChCl; N , N , N -trimethyl-methanaminium chloride, TMAC; and N , N , N -triethyl-ethanaminium chloride, TEAC) and phenol were measured at temperatures from 313.15 K to 333.15 K, pressures from 1.71 MPa to 13.3 MPa and mole ratios of phenol to QAS from 2.00 to 4.00. It has been found that two-phase equilibrium exists at all the studied conditions. The solubility of phenol in the CO 2 phase and the solubility of CO 2 in the DES phase at different pressures, temperatures, mole ratios of phenol to QAS have been obtained. Both the solubility of phenol in the CO 2 phase and the solubility of CO 2 in the DES phase formed by ChCl and phenol shows the largest, while those in the DES phase formed by TEAC and phenol shows the smallest. This work provides phase equilibrium data for phenol extraction and QAS regeneration.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2016
·Vol. 39
·期 19
·3736-3744
·
IF 2.741
Li Peng,Manman Zhu,Lingyi Zhang,Haiyan Liu,Weibing Zhang
A 3 m zwitterionic polymeric porous layer open tubular column (3 m × 25 μm id × 375 μm od) with a polymeric porous layer thickness of 4 μm was fabricated by the copolymerization of [2-(methacryloyloxy)ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide and N , N ’-methylenebis(acrylamide). The effects of the diameter of the capillary, reaction temperature, and polymerization time on the preparation of the open tubular column were investigated. Characterized by scanning electron microscopy, the zwitterionic layer was observed to be rough and throughout the fused-silica capillary homogenously, which increased the phase ratio. The separation of neutral, basic, and acidic compounds demonstrates the strong hydrophilicity of the poly[2-(methacryloyloxy)ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide coating. In addition, the poly[2-(methacryloyloxy) ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide porous layer open tubular column was applied for the analysis of flavonoids from the rootstalk of licorice, revealing the potential in separating complex samples. The relative standard deviation of retention time for run-to-run ( n = 5), day-to-day ( n = 3), and column-to-column ( n = 3) of toluene, N , N -dimethylformamide, formamide, and thiourea were below 1.2%, exhibiting good repeatability.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FUEL PROCESSING TECHNOLOGY
·
2016
·
IF 3.847
Chao Zhou,Xiangdong Zhu,Feng Qian,Wei Shen,Hualong Xu,Shicheng Zhang,Jianmin Chen
This work investigated the yields of monomeric phenols in bio-oil derived from hydrothermal liquefaction of rice straw (RS) in water and ethanol mixtures using a reductive CuZnAl catalyst. Based on the results of an initial analysis, five monomeric phenolic compounds were selected for research due to their higher concentrations, namely phenol, 4-ethyl-phenol, 2-methoxy-phenol, 2-methoxy-4-ethyl-phenol and 2,6-dimethoxy-phenol. The optimized conditions for the production of monomeric phenols can be determined as: 2 g of CuZnAl catalyst, a ratio of 50% ethanol/50% water (v/v), a temperature of 300 °C and a reaction time of 30 min. Results suggested that the maximum yield of total monomeric phenols could reach as high as ~ 26.8% (based on the mass of RS lignin), and that the aqueous phase yielded 95.5% of the monomeric phenols due to the solubilization of the ethanol. The CuZnAl catalyst was recycled five times, and a slight loss in activity was observed and examined using a number of technologies, including inductively coupled plasma , X-ray diffraction, X-ray photoelectron spectroscopy, transmission electron microscopy and energy dispersive X-ray detection. The low-cost nature of the CuZnAl catalyst makes it an ideal catalyst for the enhancement of monomeric phenols yields in water and ethanol mixtures.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）