MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Jiawei Yan,Biao Zhao,Min Li,Zuxing Zhang,Aoqun Jian,Yingxian Xue
Early and accurate detection of alpha-fetoprotein (AFP) is critical for the diagnosis and monitoring of hepatocellular carcinoma and other malignancies, However, conventional immunoassays often suffer from limited sensitivity, narrow dynamic range, and complex sample preparation. In this study, we developed a photoelectrochemical (PEC) biosensor based on Au Ag alloy nanoparticles/TiO 2 /Au (AATA) nanocomposite films, which exhibits low background noise and exceptional sensitivity for the quantitative detection of AFP. AATA nanofilms with varying component ratios were fabricated via a combination of magnetron sputtering and spin coating. The synergistic effect of localized surface plasmon resonance (LSPR) from noble metals, plasmonic coupling between the Au film and alloy nanoparticles, and the enhanced hot electron injection efficiency of Au Ag alloy nanoparticles (Au Ag ANPs) significantly improved the PEC performance of the electrode, leading to enhanced photocurrent signals. Under optimized conditions, The PEC biosensor showed a linear response between the photocurrent change and the logarithm of C AFP in the range of 0.1 ng/mL to 1000 ng/mL, with a detection limit as low as 4.54 pg/mL. Additionally, the fabricated biosensor demonstrated excellent sensitivity, stability, and reproducibility, providing a promising analytical platform for the clinical detection of AFP in human serum.
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高影响因子
MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 10
·1-9
·
IF 5.3
Feng Qianqian,Zhou Jiang,Wang Lingfeng,Gong Xiaojiao,Xi Qiang,Yang Shengyuan,Du Wenfang,Xiao Fubing
An Ag + -functionalized structural color hydrogel (Ag + -SCH) sensor is constructed for colorimetric detection of glutathione (GSH). The hydrogel is prepared by using the coordination of Ag + and 1-vinylimidazole (1-VI) as cross-linking network. GSH acts as a competitive ligand to break the coordination between Ag + and 1-VI, leading to the expansion and structural color change of the hydrogel. Quantification was achieved by measuring particle spacing changes, yielding a dynamic range of 0.1–200 μM with a limit of detection (LOD) of 0.04 μM. Alternatively, smartphone-based hue analysis enables sensitive GSH detection with a LOD of 0.79 μM. The sensor has proven to show high selectivity, excellent reusability, and long-term stability. In human serum tests, the Ag + -SCH performed comparably to commercial kits, while offering significantly lower cost. This portable, low-cost platform meets practical needs for GSH monitoring in diverse settings. Graphical abstract
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高影响因子
JOURNAL OF MATERIALS CHEMISTRY
·
2012
·Vol. 22
·期 11
·4847-4854
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IF 5.968
Desong Wang,Yandong Duan,Qingzhi Luo,Xueyan Li,Jing An,Leilei Bao,Lei Shi
A new method for the preparation of mesoporous TiO2 with a surface deposited with nanoparticles of Ag and AgBr was developed. Cetyltrimethylammonium bromide (CTAB) was used as both a template agent and bromine source in the preparation process of the mesoporous TiO2. Mesoporous TiO2 containing CTAB was synthesized by a sol–gel method, and was dipped into AgNO3 solution to form a mesoporous AgBr/TiO2 nanocomposite. The AgBr/TiO2 nanocomposite was irradiated by visible light to accelerate photolysis of AgBr, forming mesoporous Ag/AgBr/TiO2 photocatalyst. The Ag/AgBr/TiO2 photocatalyst was characterized by small angle X-ray diffraction (SAXRD), wide angle X-ray diffraction (WAXRD), transmission electron microscopy (TEM), UV-Vis diffuse reflectance spectroscopy (UV-Vis DRS), X-ray photoelectron spectroscopy (XPS), Auger electron spectroscopy (AES) and N2 isothermal adsorption–desorption. Ag/AgBr/TiO2 exhibits high photocatalytic activity for the degradation of methyl orange under visible light irradiation. The photocatalytic reaction follows the first-order kinetics and the rate constant (k) for the degradation of methyl orange photocatalyzed by Ag/AgBr/TiO2 is 63.6, 36.1 and 2.7 times that of mesoporous TiO2 (M-TiO2), commercial TiO2 (P-25), and Ag/AgBr/SiO2, respectively. The recycling runs experiment shows that the photocatalytic stability of the Ag/AgBr/TiO2 photocatalyst is excellent. The visible light photocatalytic mechanism of Ag/AgBr/TiO2 is also discussed.
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Journal of Macromolecular Science Part A-Pure and Applied Chemistry
·
2019
·
IF 1.163
Jing Chen,Qing Luo,Xiao Zhen Ma
Thermally responsive hydrogels have drawn significant research attention recently because of their simple use as smart catalyst. Here we design a series of responsive hydrogels that incorporate graphene oxide (GO)-Ag composites into thermo-responsive N-isopropylacrylamide (NIPAM) at different mass ratios. It was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), thermogravimetric analysis (TGA), and UV-visible absorption spectroscopy. Meanwhile, the PNIPAM/GO-Ag hydrogels showed high catalytic activity in the hydrogenation reaction of nitrophenol to aminophenol and acted as a tunable catalyst which the swelling and collapsing could be triggered by small temperature changes around the lower critical solution temperature (LCST) of the hydrogels. The present approach can shed new light on designing of catalytic material like GO-Ag composite responsive hydrogel with promising applications in catalysis.
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高影响因子
Journal of Materials Chemistry A
·
2015
·Vol. 3
·期 28
·14642-14650
·
IF 7.443
Yongmei Ma,Honglin Liu,Zhenzhen Han,Liangbao Yang,Jinhuai Liu
An effective near-infrared (NIR) active photocatalyst, NaYF4:Yb,Tm@TiO2/Ag (UC@TiO2/Ag) core@comby shell composite, was synthesized by a simple three-step hydrothermal process. Under the full-spectrum light of a Xe lamp in UV-Vis absorbance experiments, about 96% of R6G dyes in solution were degraded by UC@TiO2/Ag in 120 minutes, while only about 64% of the dyes were degraded by pure TiO2 under the same conditions. Under a UV-filtered Xe lamp, about 35% of the dyes were degraded by UC@TiO2/Ag in 120 minutes; interestingly, only about 8% of the dyes were degraded by pure TiO2. Under irradiation by a 785 nm laser in surface enhanced Raman scattering (SERS) experiments, the photodegradation rate constants were 0.02612 s−1 for UC@TiO2/Ag and 0.00046 s−1 for TiO2/Ag, indicating a nearly 58 fold improvement. After deducting the photobleaching effect, the photodegradation rate constants for UC@TiO2/Ag under 633 and 532 nm lasers were 0.00715 s−1 and 0.00565 s−1, respectively, revealing a sharp decrease under irradiation at shorter wavelengths. Electron spin resonance (ESR) analysis revealed that the presence of UC in this photocatalytic system certainly induced the increase of ˙OH free radicals with NIR irradiation, i.e. the UC core converts NIR light into ultraviolet (UV) light and initiates excellent photocatalytic activity of the TiO2/Ag comby shell. Furthermore, the decorating of Ag nanoparticles not only enhances the photocatalytic ability, but also provides a structural basis for monitoring the photocatalytic kinetics by the SERS technique. By virtue of monochrome laser lines, SERS analysis provides direct evidence to prove the capability of UC-initiated non-UV photocatalysis and the improvement of the utilization of non-UV lights on TiO2. The results revealed that this new photocatalytic platform can efficiently utilize different bands of the solar spectrum and also find new applications in SERS fields.
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Journal of Energy Chemistry
·
2024
·
IF 14
Yaning Liu,Tianqi Yang,Ruyi Fang,Chengwei Lu,Ruojian Ma,Ke Yue,Zhen Xiao,Xiaozheng Zhou,Wenkui Zhang,Xinping He,Yongping Gan,Jun Zhang,Xinhui Xia,Hui Huang,Xinyong Tao,Yang Xia
The unstable electrolyte/lithium (Li) anode interface has been one of the key challenges in realizing high energy density solid-state lithium metal batteries (LMBs) applications. Herein, a dense and uniform silver (Ag) nano interlayer with a thickness of ∼35 nm is designed accurately by magnetron sputtering technology to optimize the electrolyte/Li anode interface. This Ag nano layer reacts with Li metal anode to in-situ form Li-Ag alloy, thus enhancing the physical interfacial contact, and further improving the interfacial wettability and compatibility. In particular, the Li-Ag alloy is inclined to form AgLi phase proved by cryo-TEM and DFT, effectively preventing SN from continuously “attacking” the Li metal anode due to the lower adsorption of succinonitrile (SN) molecules on AgLi than that of pure Li metal, thereby significantly reinforcing the interfacial stability. Hence, the enhanced physical and chemical stability of electrolyte/Li anode interface promotes the homogeneous deposition of Li + and inhibits the dendrite growth. The Li-symmetric cell maintains stable operation for up to 1700 h and the cycling stability of LiFePO 4 |SPE|Li full cell is remarkably improved at room temperature (capacity retention rate of 91.9% for 200 cycles). This work opens an effective way for accurate and controllable interface design of long lifespan solid-state LMBs.
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Reaction Kinetics Mechanisms and Catalysis
·
2024
·Vol. 137
·期 2
·1225-1238
·
IF 1.7
Wang Wanchun,Chi Yangxu,Sun Jiahong,Zhou Feng,Zhan Su
In this work, Ag/CuBi 2 O 4 composite photocatalyst films with excellent photocatalytic sterilization properties were prepared by photodeposition. The photocatalytic activity of silver-modified CuBi 2 O 4 (Ag/CuBi 2 O 4 ) under the photocatalytic-Fenton coupling system was verified by its inactivation rate of Escherichia coli in seawater. The results showed that the photocatalytic sterilizing performance of CuBi 2 O 4 loaded with Ag in the presence of trace amounts of H 2 O 2 was significantly improved. 15Ag/CuBi 2 O 4 possessed the optimal photocatalytic activity, and its sterilizing rate in 30 min could reach 96.6%. Its sterilization rate in 30 min could reach 96.6%, which is about 70% higher than that of pure CuBi 2 O 4 . Meanwhile, the mechanism of the enhanced sterilization performance of Ag/CuBi 2 O 4 in the photocatalytic-Fenton coupled system was investigated. Firstly, according to the electrochemical results, the loading of Ag can significantly improve the charge separation efficiency of CuBi 2 O 4 . And promotes the conversion of H 2 O 2 to hydroxyl radicals(·OH); Secondly, the valence band potential of 15Ag/CuBi 2 O 4 is more positive than that of CuBi 2 O 4 , which suggests that Ag loading can enhance the oxidation of CuBi 2 O 4 cavities. Comprehensive radical trapping experiments demonstrate that ·OH and holes (h + ) are the main active species for inactivating Escherichia coli (E. coli). In this work, effective conversion of H 2 O 2 to ·OH in a wide spectral range was achieved by loading Ag nanoparticles on the surface of CuBi 2 O 4 , which provides a new idea for the development of photocatalytic-Fenton coupling technology and ballast water treatment. Graphical abstract
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OPTICS AND LASER TECHNOLOGY
·
2025
·
IF 5
Shi Wang,Yue Li,Yafang Pan,Xiaolong Song,Liu Wang,Mingli Wang
Modifying nanoparticle assembly can alter the electric field strength within “hot spots,” offering promise for enhancing surface-enhanced Raman scattering (SERS) performance. In this work, by modifying the surface of Ag nanoparticles (AgNPs) with glutathione (GSH), a pH-responsive substrate, Ag-GSH nanoparticles (AGGNPs), was prepared. Under acidic conditions, hydrogen bonds form between protonated GSH molecules, inducing aggregation of AGGNPs and causing a red shift in the absorption peak. The SERS enhancement factor (EF) increased from 5.6 × 10 5 to 1.36 × 10⁶ and exhibited a good linear relationship with pH. In practical apple sample detection, the natural acidic environment of the fruit pulp enabled SERS self-optimization. Without external acid addition, the signal for thiram at 1383 cm −1 was significantly enhanced, achieving a minimum detection concentration of 10 −11 M. This approach effectively provides a novel pathway for developing highly efficient SERS sensing strategies and offers fresh insights for expanding SERS applications in agricultural detection.
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高影响因子
TALANTA
·
2020
·
IF 5.339
Yueyue Tian,Yancao Chen,Mei Chen,Zhi-Ling Song,Bin Xiong,Xiao-Bing Zhang
Here we report the peroxidase-like [email protected] nanozyme as an integrated nanosensor for selective detection of silver ions (Ag + ), where the nanozyme plays the roles as both the signal trigger and reporter simultaneously. This method relies on two critical chemical reactions, including (1) the unique inhibitory effect of Ag + on the nanozyme triggered H 2 O 2 decomposition at weak acid environment and (2) H 2 O 2 induced Ag + reduction onto the nanozyme surface at basic environment, leading to a blueshift in the localized surface plasmonic resonance wavelength (LSPR λ max ) of the nanosensor. With this simple strategy, we demonstrated the sensitive and selective detection of Ag + over a dynamic range from 0.5 to 1000 μM with a limit of detection (LOD) of 500 nM by UV–visible spectroscopy, which is below the permitted level of Ag + in drinking water by U.S. Environmental Protection Agency (EPA). This method also exhibits satisfying recovery efficiency for Ag + detection both in tap water and spring water from the Yuelu Mountain. With this satisfying sensing performance and excellent stability of nanoprobes, this strategy is promising for the detection of Ag + in environment monitoring and food safety analysis.
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高影响因子
CARBON
·
2026
·
IF 12.7
Youming Luo,Yaling Huang,Xuhui Zhang,Mingxuan Tang,Yucan Lei,Wendan Wang,Quanfang Chen
Simultaneously enhancing the mechanical strength and electrical conductivity of aluminum-matrix composites remains challenging because conventional strengthening strategies usually introduce defects and interfaces that intensify electron scattering. In this work, graphene surfaces were coated with Ag or Ni via electroless deposition to regulate the graphene/Al interface through work-function differences. Few-layer graphene was coated with Ag (lower work function than graphene) or Ni (higher work function than graphene) via electroless deposition, dispersed into aluminum powders by ball milling, and consolidated by high-pressure sintering at 1 GPa. The Ni-coated graphene/Al composite achieves an ultimate tensile strength of 336 MPa, corresponding to a 78.7% increase over identically processed pure aluminum. In contrast, the Ag-coated graphene/Al composite delivers an electrical conductivity of 73.37% IACS, representing a 17.58% improvement relative to the pure aluminum, while maintaining a high ultimate tensile strength of 318 MPa. The optimization of the ultimate tensile strength and conductivity follows distinct pathways, governed respectively by interfacial phase-architecture strengthening and work-function-induced electronic doping. This strategy offers a scalable route for synergistically regulating interfacial phases and electronic structures toward high-strength and high-conductivity aluminum-matrix composites for structural–functional integration. Download: Download high-res image (322KB) Download: Download full-size image
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.6
Zhiming Chen,Jiabin Chen,Haoming Bao,Kaitao Liu,Pan Zeng,Fan Yang,Wei Cao,Dongqi Yang,An Cao,Tao Zhang,Yue Li
Surface-enhanced Raman scattering (SERS) has been one of the efficient strategies for trace molecular analysis, but the traditional substrates with sharp tips cannot effectively detecting the molecular isomers. Here, we develop a facile way to fabricate large-area, reproducible Ag/Au nanocavity arrays by the combination of microsphere-templated soft lithography and self-assembly. Compared to the flat and convex substrate, the Ag/Au units arranged on the concave surface exhibit a high-density of hotspots via spatial light confinement and multi-reflection-enhanced electromagnetic coupling, which enables highly sensitive detection of probe molecules down to10 −12 M. Moreover, by integrating machine learning algorithms, the test set shows a coefficient of determination (R 2 ) of 0.9896, achieving advanced training performance for classifying four structurally analogous quinolone antibiotics (ciprofloxacin, enrofloxacin, danofloxacin, and enoxacin) with a quantitative prediction of 10 −10 M. This work demonstrates a robust pathway for the controllable fabrication of high-performance SERS substrates for the development of intelligent, quantitative, and on-site sensing platforms in complex practical scenarios. Download: Download high-res image (179KB) Download: Download full-size image
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19.9
Bing Xie,Wenpeng Gao,Zhiyong Liu,Kun Guo,Qingping Wang,Shenglin Jiang,Chris Bowen,Huajie Luo,Tianyu Li
Piezocatalysis, the direct conversion of mechanical energy into chemical reactivity, offers a promising route for sustainable pollutant removal and chemical synthesis. However, practical applications require materials that are able to simultaneously deliver high activity, stability, and ease of recycling. Here, we report a flexible micro-nano-engineered BaTiO 3 /PVDF@Ag composite film, whereby {111} BaTiO 3 single-crystal microsheets are embedded in a poly (vinylidene fluoride) (PVDF) matrix and decorated with photo-deposited Ag nanoparticles. This BaTiO 3 /PVDF@Ag composite microstructure design endows the optimal composite with outstanding piezocatalytic performance, including a Rhodamine B degradation rate constant of 0.24 min −1 , a hydrogen peroxide generation rate of 3520 µmol g −1 h −1 , and a CO 2 reduction rate of 535 µmol g −1 h −1 , while maintaining its activity over repeated cycles. Systematic structural, spectroscopic, and electrochemical characterization, together with theoretical simulations, reveal that the ferroelectric BaTiO 3 and electroactive β -phase PVDF enhance the local piezoelectric potential under mechanical stimulation, while the Ag nanoparticles act as efficient electron traps and catalytic sites. Interfacial polarization as resulting from the dielectric and conductivity mismatches between the composite components also reduces charge-transfer resistance and thereby accelerates carrier separation and migration. These synergistic effects enable efficient formation of reactive oxygen species, thereby driving high H 2 O 2 yields and CO 2 reduction. The mechanically robust film can also be easily recovered and reused, demonstrating a viable route to green, high-performance piezocatalysts for environmental applications.
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