HIGH PERFORMANCE POLYMERS
·
2014
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IF 1.09
Yunliang Guo,Shuling Zhang,Lilong Yang,Feng Li,Wenlei Li,Yinlong Du,Guibin Wang
An amphiphilic hyperbranched rod-coil copolymer was synthesized by grafting linear poly (ethylene glycol) (PEG) onto hydroxyl-terminated hyperbranched poly (aryl ether ketone) (OH-HPAEK). The molecular structure, the number-average molecular weight and the thermal properties of HPAEK-block-PEG were confirmed and characterized using proton nuclear magnetic resonance, Fourier transform infrared spectroscopy, gel permeation chromatography, differential scanning calorimetry, and thermogravimetric analysis, respectively. The microspheres of HPAEK-block-PEG were fabricated by the method of self-assembly, and the morphology and diameter of the obtained microspheres were characterized using transmission electron microscopy, scanning electron microscopy, and dynamic light scattering. The heat-treated experimental results demonstrated that the polymer microspheres possessed excellent thermal property that could stably exist even if heated at 130°C for 10 h. In addition, the diameter of the microspheres can be easily controlled by just adjusting the concentration of the copolymer.
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FLUID PHASE EQUILIBRIA
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2015
·
IF 2.2
Yang Feng,Entao Yang,Leping Dang,Hongyuan Wei
Liquid–liquid phase equilibrium data for ternary systems containing formamide (or ethylene glycol (EG), monoethanolamine (MEA) + indole + 2-methylnaphthalene (2-MN) at 308.15 K under atmospheric pressure were measured in this work. The results show that all the three ternary systems are Treyball type 1 systems. The experimental data were correlated well using both the non-random two liquid (NRTL) model and universal quasi-chemical activity coefficient (UNIQUAC) model. In addition, both the distribution coefficient and selectivity coefficient of formamide, EG and MEA were calculated to investigate the feasibility of extracting indole from 2-MN and formamide presented a better selectivity.
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JOURNAL OF SUPERCRITICAL FLUIDS
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2013
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IF 2.732
Di Duan,Baogen Su,Zhiguo Zhang,Zongbi Bao,Yiwen Yang,Qilong Ren
Three new CO 2 -philic open-chain organophosphorous chelating ligands, i.e. ethylene glycol bis(2-isopropoxyethyl) dimethyl diphosphate (EG2IPE), triethylene glycol bis(2-isopropoxyethyl) dimethyl diphosphate (EG3IPE), and tetraethylene glycol bis(2-isopropoxyethyl) dimethyl diphosphate (EG4IPE), were synthesized and characterized. Solubilities of these ligands in scCO 2 were determined at different combinations of temperature (313.15⿿333.15 K) and pressure (9⿿20 MPa), which generally showed considerable solubility in each case. These experimental data are in agreement with computed data via a semi-empirical model, in which the average absolute relative deviations lie in the range of 4.09⿿4.95%. The effect of these ligands on supercritical fluid extraction of selected rare earth metals (La 3+ , Ce 3+ , Pr 3+ , Nd 3+ , Sm 3+ , Gd 3+ , Er 3+ , and Yb 3+ ) was investigated at 313.15 K and 20 MPa. The extraction efficiency of this system was found to increase in the order EG4IPE < EG3IPE < EG2IPE with a range from 55% to 79%. The rationale behind different selectivities toward these metals was also discussed in comparison to other traditional organophosphorous agents. A detailed experimental analysis of the complexation patterns by means of a combination of IR, 1 H NMR and ESI-MS has revealed that the interaction of ether oxygen group in EG4IPE with metals and the corresponding extraction mechanism.
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JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
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2016
·Vol. 54
·期 16
·2571-2581
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IF 3.114
Yan Zhang,Miao Wang,Jinhai Ye,Meidong Lang
Novel poly( ε -caprolactone)- b -poly(ethylene glycol)- b -poly( ε -caprolactone) (PCL-PEG-PCL) bearing pendant hydrophobic γ -(carbamic acid benzyl ester) groups (PECB) and hydrophiphilic amino groups (PECN) were synthesized based on the functionalized comonomer γ -(carbamic acid benzyl ester)- ε -caprolactone (CABCL). The thermal gelation behavior of the amphiphilic copolymer aqueous solutions was examined. The phase transition behavior could be finely tuned via the pendant groups, and an abnormal phenomenon occurred that the sol–gel transition temperature shifted to a higher temperature for PECB whereas a lower temperature for PECN. The micelles percolation was adopted to clarify the hydrogel mechanism, and the effect of the pendant groups on the micellization was further investigated in detail. The results demonstrated that the introduction of γ -(carbamic acid benzyl ester) pendant groups significantly decreased the crystallinity of the copolymer micelles whereas amino pendant groups made the micelles easy to aggregate. Thus, the thermal gelation of PEG/PCL aqueous solution could be finely tuned by the pendant groups, and the pendant groups modified PEG/PCL hydrogels are expected to have great potential biomedical application. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2016 , 54 , 2571–2581
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MACROMOLECULAR MATERIALS AND ENGINEERING
·
2016
·Vol. 301
·期 3
·287-295
·
IF 2.834
Xueqin Zhang,Huihui Wang,Xiaoxiang Wen,Aiping Zhang,Xiaoying Wang,Linxin Zhong,Chuanfu Liu,Runcang Sun
The objective of this study is to broaden the application of xylan as moisture-absorption/retention biomaterials by grafting polyethylene glycol (PEG) on xylan backbone. Ionic liquid 1-allyl-3-methylimidazolium chloride ([Amim]Cl) and 4,4-diphenylmethane diisocyanate are used as reaction media and coupling reagent, respectively. FT-IR, 1 H-NMR, and gel permeation chromatography analyses indicate the successful occurrence of the grafting reaction. Thermogravimetric analysis/derivative thermogravimetry indicates that the thermal stability of xylan increases after the grafting of the PEG side chains. With an increase of the degree of substitution of xylan- g -PEG, the molecular weight ( M w ) of PEG side chains (1000 and 5000 g mol −1 ), and the relative humidity of environment, the moisture-absorption/retention ratio of xylan- g -PEG increases. To evaluate the biodegradability/biocompatibility of this promising material, the ratio of biochemical oxygen demand to chemical oxygen demand of xylan- g -PEG and the cytotoxicity are tested on the samples. The results indicate that PEG-modified xylan has great potential as moisture-absorption/retention biomaterials.
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POLYMER INTERNATIONAL
·
2017
·Vol. 66
·期 11
·1579-1586
·
IF 2.07
Lanxia Zhao,Xia Zhang,Xin Liu,Juan Li,Yuxia Luan
The synthesis, characterization and potential application in the doxorubicin (Dox) delivery system of a biodegradable polypeptide-based block copolymer, poly(ethylene glycol) 2000 -poly(ϵ-caprolactone) 6000 -poly(glutamic acid) 1000 (PEG 2000 -PCL 6000 -PGA 1000 ), was investigated. The copolymer was synthesized via ring-opening polymerization and characterized by 1 H NMR and Fourier transform IR. The synthesized copolymer could self-assemble into aggregates and the critical aggregation concentration was 0.23 mg mL −1 . Transmission electron microscopy indicated that spherical polymersomes formed with a desirable size about 180 nm. Therefore Dox was encapsulated into these polymersomes, and then we investigated its applications in a drug delivery system. These Dox-loaded polymersomes (PolyDox) were characterized by dynamic light scattering, zeta potential and pH responsiveness measurements. In vitro drug release indicated that the release rate of drug from PolyDox was pH-responsive and significantly decreased. The drug pharmacokinetic parameters were improved in comparison to the group treated with free Dox, which proved the prolonged Dox release from PolyDox. A WST-1 assay indicated a low toxicity and good compatibility of copolymer to cells within 48 h. The results also showed that PolyDox appeared to induce a higher anti-tumor effect. Cell uptake results indicated that PolyDox displayed higher cellular uptake in A549 cells. Endocytosis inhibition results demonstrated that the internalization of PolyDox was mostly mediated by the fluid-phase endocytosis pathway. © 2017 Society of Chemical Industry
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LANGMUIR
·
2017
·
IF 3.833
Lan Ma,Hui Tang,Peiyi Wu
The microdynamic volume phase transition mechanism of poly[di(ethylene glycol)ethyl ether acrylate] (PDEGA)-based microgels with newly developed thermoresponsive polyionic liquid (PIL) (poly(tetrabutylphosphonium styrenesulfonate) P[P4,4,4,4][SS]) moieties was studied by applying temperature-variable Fourier transform infrared (FTIR) spectroscopy in combination with two-dimensional correlation spectroscopy (2Dcos) and the perturbation correlation moving window (PCMW) technique. It can be found that the content of hydrophilic PIL moieties plays a significant role in the thermally induced phase transition behavior of microgel systems; namely, the microgels containing fewer PIL moieties present a sharp transition behavior and a gel-like state (10%, w/v) in water whereas the microgels with more PIL moieties undergo a slightly broad phase transition process and a flowable solution state. Herein, the C═O···D2O-PIL hydrogen bonds as the interaction between PDEGA and P[P4,4,4,4][SS] moieties result in a complete dehydration process for the microgels with fewer PIL moieties and the dehydrated behavior of SO3– groups acts as the driving force during the phase transition. As for the microgels with more PIL moieties, the whole transition process is dominated by the hydrophobic interaction of C–H groups. Even though the intermolecular hydrogen bonds (C═O···D2O-PIL) appear as well, the more remarkable effect of the Coulombic repulsive force of PIL restrains the water molecules from breaking away, thus causing a gradual and incomplete dehydration process during heating.
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PubMed
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2017
·
IF 3.582
Tianjun Hu,Ying Wang,Qing Liu,Lina Zhang,Hongbo Wang,Tao Tang,Wenwen Chen,Man Zhao,Jianfeng Jia
To achieve the better electrocatalytic activity and stability of Pd-base catalysts for ethylene glycol and glycerol oxidation reactions, a novel Pd-base binary Pd Co oxides nanoparticles (Pd PdO-CoO x ) was synthesized by in-situ oxidation of Pd Co precursor. The strategy was simple, mild, green and efficient. The prepared nanoparticles exhibited a mutually connected, fused irregular nanoparticles in TEM. The as-synthesized Pd PdO-CoO x (1:4) nanoparticles displayed prominent catalytic activity (5.82 A m g Pd − 1 for ethylene glycol and 5.16 A m g Pd − 1 for glycerol) for ethylene glycol and glycerol oxidation reactions in alkaline solution compared to the commercial Pt/C (1.64 A m g Pt − 1 for ethylene glycol and 1.48 A m g Pt − 1 for glycerol) catalyst. The improved electrocatalytic activity of Pd PdO-CoO x catalyst mainly ascribes to the producing Strong Metal-Support Interactions (SMSI) between PdO-CoO x and Pd nanoparticles, the synergistic effect between PdO and CoO x and the presence of CoO x promoved hydroxyl adsorption at lower potentials. Combined with the simple synthetic method, lower cost and good performance, Pd PdO-CoO x is a promising catalyst for direct fuel cells.
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ADVANCED FUNCTIONAL MATERIALS
·
2024
·
IF 18.5
Ying Yang,Xuebo Cao,Lin Huang,Quankun Li,Li Gu,Zheng Yan,Mengli Li,Ruobin Cheng,Zhufeng Lu,Ai-Jun Wang,Wenchao Yang
Electrochemical oxidization of crude ethylene glycol (EG) to fine chemicals driven by sustainable energy is an eco-friendly solution to the upcycling of end-of-life polyethylene terephthalate (PET) wastes. Here, pseudo Ag x -Pt y Pd z core–shell electrocatalyst capable of hybrid oxidation of EG to formate (FA) is designed and synthesized. The trimetallic system consists of Ag nanowire and ultrathin PtPd alloy skin with defects, such as holes and grooves. The defects expose the Ag core to the surroundings and convert Ag 0 to Ag 2+ active species at appropriate potential (> 1.2 V vs RHE). Thus, hybrid EG oxidization reaction is realized on the Ag x -Pt y Pd z electrocatalyst, where PtPd skin catalyzes EG oxidization through conventional Faradaic electrode process owing to inherent activities of Pt and Pd, while Ag 2+ serves as auxiliar oxidant to oxidize EG/intermediates (non-Faradaic reaction). Such a hybrid oxidization strategy reinforces the removal of adsorbates on Ag x -Pt y Pd z electrocatalyst and refresh the active sites timely. Eventually, ultrahigh specific activity (24.45 A mg −1 PtPd ) and long-term stability (> 3000 h at current density ≥ 400 mA cm −2 ) are delivered by the system. The finding of Ag 2+ -enhanced alcohol oxidization reactions introduces a new paradigm for designing high-performance electrocatalysts for energy and environmental applications.
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Heliyon
·
2024
·
IF 3.4
Qibin Zhao,Hao Liang
Natural gas hydrate has been a critical risk to the safety of offshore oil and gas well test and subsea transportation. Herein, the effect of three quaternary ammonium salt (QAS) surfactants with monoethylene glycol (MEG) to methane hydrate agglomeration in water-oil system was experimentally studied by a rocking cell. Based on the hydrate volume fraction and the slider trajectory, a classification method of the gas hydrate anti-agglomerants was established. All the QASs in this work show the capability of reducing hydrate agglomeration, among which N 1 ,N 3 -didodecyl-N 1 ,N 1 ,N 3 ,N 3 -tetramethylpropane-1,3-diaminium chloride (AA-2) has the best anti-agglomerating performance, and the slider moved at a large trajectory of 61–174 mm. The three QASs were compounded with 5, 10, and 15 wt% (based on water) MEG, respectively. Experimental results showed that AA-2 compounded with MEG (10 wt%) can effectively prevent hydrate agglomeration. The slider moved in the cell at the full trajectory range, showing the compound of grade A performance. The compound of QAS and MEG shows a synergistic effect. The addition of QAS can significantly reduce the required MEG dosage for the hydrate blockage prevention than the MEG only situation. Considering the economic factors of the filed hydrate management, the combination application of QAS + MEG may provide a promising option.
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PubMed
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ELECTROCHEMISTRY COMMUNICATIONS
·
2024
·
IF 4.7
Zhiwen Shi,Lijuan Qiao,Mei Ma,Zhi Jia,Bingxin Liu,Li Gao
Ethylene glycol is odorless and harmful to humans. Each year, a large number of fatal cases are caused by ethylene glycol poisoning. Therefore, rapid identification of ethylene glycol is crucial. In this study, clay-like Ti 3 C 2 T x MXene exhibits a larger interlayer spacing compared to accordion-like Ti 3 C 2 T x MXene, which enhances the gas diffusion channels. Nitrogen doping can increase the active sites of clay-like Ti 3 C 2 T x MXene. The introduction of nitrogen-doped carbon nanotubes into N-Ti 3 C 2 T x was carried out to enhance selectivity towards ethylene glycol, leading to the formation of N-Ti 3 C 2 T x MXene/N-CNTs. The N-Ti 3 C 2 T x MXene/N-CNTs exhibits significant selectivity towards the ethylene glycol at room temperature. Meanwhile, the detection limit was 0.3484 ppm, with a shortened response/recovery time of 10.57/6.29 s. Meanwhile, the ethylene glycol sensor device has been prepared through custom-made circuit boards and sensing programs. Moreover, the adsorption and oxidation process of ethylene glycol on N-Ti 3 C 2 T x MXene/N-CNTs was explored through in-situ infrared spectroscopy testing. This study revealed that the oxygen vacancies on the surface of N-Ti 3 C 2 T x MXene/N-CNTs play a crucial role in the oxidative catalytic detection of ethylene glycol. The strategy of N-Ti 3 C 2 T x MXene/N-CNTs provides a new avenue for the detection of ethylene glycol.
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JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2024
·
IF 4.5
Hairong Chen,Guichun Wang,Xiaoliang Li,Jingjing Wang,Xinrui Wang,Yuxiao Wang,Zhenzhen Liu,Jiajia Liu,Yang Ding,Jian Guo,Shuangying Gui
Pueraria flavonoids (PF), the main component of “Getong Tongluo capsule”, were applied in the clinical treatment of cardiovascular diseases. However, the complex nature of multiple-components, along with poor stability and low oral bioavailability of PF, hinders its widespread clinical use. This study aimed to develop D-alpha-tocopheryl polyethylene glycol succinate (TPGS) surface-modified PF-loaded nanocrystals (PF–NCs)，and investigate their physico-chemical properties and oral absorption mechanism. The prepared PF-NCs showed as rod shape crystal with an average particle size and polydispersity index of 259.0 ± 7.80 nm and 0.195 ± 0.046. Compared with PF, the stability of PF-NCs was significantly improved. Furthermore, the transport of PF-NCs in Madin-Darby canine kidney (MDCK) monolayers was time-, concentration- and energy-dependent. The endocytosis of PF-NCs was mediated mainly through macropinocytosis, caveolin, clathrin and lipid rafts/caveolae. The involvement of multidrug resistance-associated protein 2 (MRP2) transporter and P-gp in the transmembrane transport of PF-NCs was also significant. Pharmacokinetic studies demonstrated that PF-NCs exhibited a substantial enhancement of PF's oral bioavailability. Overall, the prepared PF-NCs demonstrated enhanced stability and bioavailability, offering valuable insights for the development of multi-component nanocrystals and investigation into their mechanisms of oral absorption.
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