FOOD RESEARCH INTERNATIONAL
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2026
·
IF 8.8
Qingluan Li,Wenhui Geng,Yibin Ying,Lijuan Xie
Neonicotinoids (NEOs) pose significant threats to environmental safety and the food chain. To overcome the limitations of conventional nanozymes in achieving simultaneous pesticide discrimination and ultrasensitive quantification, a tunable platinum/gold@manganese dioxide (Pt/Au@MnO 2 ) nanozyme was developed. The material was engineered by synthesizing urchin-like Pt/Au nanoparticles via a two-step hydrothermal method, followed by electrostatic self-assembly onto MnO 2 nanosheets. By modulating the Pt/Au to β-MnO 2 ratio, the nanozyme's activity could be precisely switched between laccase-like (LAC) and peroxidase-like (POD) modes. The LAC mode enabled discriminative analysis of four NEOs through distinct colorimetric fingerprints analyzed by principal component analysis (PCA). For quantification, the POD mode was amplified by glutathione (GSH), which enhanced the signal through a nucleophilic reaction, resulting in a visible color gradient from dark green to light yellow. This strategy achieved highly sensitive detection of imidacloprid with a wide linear range (10 −8 –10 −4 M), a low detection limit of 4.42 × 10 −9 M, and high accuracy in real samples (recoveries: 96.2–104.0%). This dual-mode platform offers a robust and practical strategy for on-site NEO monitoring in food safety and agricultural control.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
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IF 5.4
Zhengshen Bao,Dehong Xu,Hailong Peng,Changqing Xia,Shixing Wang,Weili Li
Efficient recovery of Au (III) from aqueous wastewater is of great significance for resource utilization and environmental protection. Herein, azine-functionalized Zr-based MOFs (hereinafter referred to as AZA-Zr-MOFs) were prepared via a facile one-pot solvothermal route using 2,2'-diamino-4,4'-(4-amino-1,2,4-triazole-3,5-diyl) dibenzoyl acid as the organic linker. The abundant triazole and amino groups on the MOF surface provide multiple active sites for multi-nitrogen synergistic coordination, thus enhancing the selective capture of Au (III) in aqueous solution. The obtained AZA-Zr-MOFs exhibit a high maximum uptake capacity of 1176 mg/g for Au(III), along with remarkable selectivity and excellent cycling stability (＞90 % efficiency after 5 cycles) over a wide pH range (2.0~9.0). Combined with experimental analyses (X-ray photoelectron spectroscopy (XPS), zeta potential, Fourier transform infrared spectroscopy (FTIR)) and density functional theory (DFT) calculations, the liquid-phase adsorption mechanism of Au (III) is clarified as a synergistic effect of amino-assisted reduction (Au (III)→Au (0)), nitrogen-centered coordination on the MOF surface, and electrostatic interfacial interaction via protonated amino groups. This work provides a feasible preparation method for MOF-based adsorbents and reveals the key role of surface functional groups in the interfacial adsorption of Au (III), which has potential application value for Au (III) recovery from actual aqueous wastewater.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Xiaohui Xu,Xinyue Wang,Qiang Xie,Jingyao Wu,Kwangnak Koh,Hongxia Chen
Ternary MXene/AuNRs/pSC4 interface enables oriented antibody immobilization. • 1.15 ng mL −1 detection limit in serum, 10–200 ng mL −1 linear range. • Hydrophilic MXene/AuNRs surface resists biofouling without serum pretreatment. • 5.7× signal gain over single-component devices via synergistic amplification. • Clinically distinguishes PD patients from healthy controls ( p < 0.001). Parkinson's disease (PD) management requires point-of-care accessible tools for personalized monitoring of levodopa therapy. Plasma dopa decarboxylase (DDC), a drug-responsive biomarker, has emerged as a promising target to guide dosing and anticipate adverse effects. However, current DDC assays rely on costly, labor intensive platforms that preclude rapid, sensitive detection in complex biological fluids. Here we report an electrochemical biosensor based on a novel ternary supramolecular interface combining MXene, Au nanorods, and p-sulfonatocalix[4]arene (pSC₄). In this design, pSC₄ serves as a supramolecular adapter to orient anti DDC antibodies via host–guest recognition, while the MXene/AuNRs hybrid provides synergistic signal amplification and contributes to reduced nonspecific adsorption. The sensor achieves a detection limit of 1.15 ng mL −1 and a linear range of 10–200 ng mL −1 in undiluted human serum, representing an approximately 5.7 fold signal amplification over single component devices. In an exploratory study of 12 subjects (6 PD patients under chronic dopaminergic therapy, 6 healthy controls), sera from PD patients showed a significantly higher ΔRct than controls (approximately threefold, P < 0.001). This work establishes an analytical proof-of-concept for DDC detection by integrating supramolecular chemistry with nanomaterials, providing a foundation for future clinical studies. Download: Download high-res image (109KB) Download: Download full-size image
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IEEE SENSORS JOURNAL
·
2026
·Vol. 26
·期 9
·13234-13242
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IF 4.5
Fangzheng Wang,Yunhao Ma,Liyin Hu,Xingjun Yue,Xin Yan
In this work, a high-performance sensor based on a multimode fiber-thin core fiber-multimode fiber (MMF–TCF–MMF) structure is demonstrated. By using a continuous Au film and covalently anchored AgNPs on the TCF surface, the synergistic coupling between exciting surface plasmon resonance (SPR) and localized surface plasmon resonance (LSPR) is realized. Following a systematic optimization guided by COMSOL simulations and experimental validation, the refractive index (RI) sensitivity reached 2525.06 nm/RIU with a figure of merit (FOM) of 9.494 RIU−1, and the temperature sensitivity reached −1.07 nm/°C. The system demonstrated excellent linearity, repeatability, and stability. The proposed sensor effectively merges cost-efficiency with robust precision, showing significant potential for biochemical, environmental, and industrial sensing applications.
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Analytical Methods
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2026
·
IF 3
Liansheng Ling,chen chen,Yingqing Li,xiaosong Yang,Ji Zhang
Here we report an ultrasensitive dynamic light scattering (DLS) immunosensor for cardiac troponin I (cTnI) leveraging a novel Self-cascading reaction synergistic amplification strategy by using metal organic frameworks (MOF) materials. This synergistic amplification system was designed within combined enzymatic (glucose oxidase, GOD) catalysis, acid-responsive MOF disintegration, Fenton reaction and gold nanoparticles (Au NPs) stability modulation. When the target cTnI was present, sandwich structure was formed between multifunctional probes (Ab-GOD/Fe-MOF) and Ab modified 96-well plates, subsequently occurring self-cascading reactions with further addition of glucose: the glucose was oxidized into gluconic acid (creating an acidic micro-environment) by O2 under the catalysis of MOF - conjugated GOD and produced H2O2, the acidic micro-environment triggered the breakdown of Fe-MOF and the release of Fe2+, reacting with H2O2 via the Fenton reaction to etch the protective DNA layer that modified on Au NPs, enable the salt-induced aggregation of AuNPs. Crucially, the DLS assay achieved a low limit of detection (LOD) of 1.5 × 10-13 g/mL, furthermore, this cascade amplification strategy realized the quantitative detection of cTnI in clinical samples with high sensitivity and specificity.
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IEEE SENSORS JOURNAL
·
2026
·
IF 4.5
Pengxia Li,Zhifei Cao,Bin Xie,Guowei Yang,Yifei Ma,Mei Wang,Suotang Jia,Xuyuan Chen,Zhaomin Tong
Gas sensors play a vital role in human health monitoring, particularly for detecting disease-related biomarkers in exhaled breath. However, conventional metal-oxide semiconductor gas sensors face limitations in wearable respiratory monitoring applications due to their inflexibility and high heat loss. Here, we fabricated an Au-ZnO fibre-based gas sensor for the detection of ammonia (NH3), an indicator of kidney dysfunction. The device is constructed from a composite flexible fibre comprising a liquid-metal core and a silica cladding, onto which an Au-ZnO gas-sensing layer is synthesised in situ. Liquid metal directly conducts thermal energy to the insulating cladding through Joule heating, providing thermal energy to the gas-sensing layer. This design enables low heat loss and low-current operation while generating sufficient thermal energy to enhance the gas-sensing response. The resulting Au-ZnO fibre sensor exhibits a stable high response to NH3 (response of 2.2 to 2 ppm NH3) even under bending (bending radius of 15 mm). The response time and recovery time are 153 s and 156 s at a working temperature of 280 oC. This demonstrates that the Au-ZnO fibre sensor has good flexibility and suitability for wearable respiratory monitoring. To showcase its practical utility, a real-time monitoring sensor system was developed by designing a signal detection circuit, and the concentration of NH3 was monitored in real time through different coloured light-emitting diodes. This work presents a practical, home-based approach for respiratory monitoring of NH3 and offers a simple, effective solution to distinguish between healthy individuals and patients with different stages of kidney disease.
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Catalysts
·
2026
·Vol. 16
·期 5
·480
·
IF 4.5
Qifan Zhao,Kaijie Li,Hongbo Yu,Hongfeng Yin
p-nitrophenol (p-NP) is a pollutant with environmental persistence, bioaccumulation potential, and significant health risks, and is widely dispersed in wastewater, so efficient removal ofp-NP is imperative. Among the various methods, the catalytic reduction ofp-NP top-aminophenol (p-AP) using sodium borohydride (NaBH4) is a particularly promising one and, herein, catalysts play a crucial role. Among the various metals, Au shows unique catalytic activity forp-NP reduction. However, nanosized Au often exhibit limited activity and stability due to their high surface free energy. To address this challenge, we designed and synthesized Au-SnOxhybrid nanoparticles confined within hollow mesoporous silica nanoreactors (Au-SnOx@hm-SiO2) via a soft-template-assisted co-adsorption strategy. The resulting bimetallic Au-SnOx@hm-SiO2nanoreactor showed significantly enhanced catalytic activity toward the NaBH4-mediated reduction ofp-nitrophenol (p-NP) compared with its monometallic Au@hm-SiO2counterpart, owing to the synergistic effect between Au and SnOx. Among various Au/Sn ratios, the catalyst with an Au/Sn molar ratio of 1:0.1 demonstrated the highest activity, achieving complete conversion ofp-NP within 5 min at ap-NP/Au molar ratio of 529:1—a tenfold improvement over Au@hm-SiO2. Moreover, the catalyst maintained high efficiency over six consecutive cycles, with only slight deactivation, benefiting from the protective silica shell.
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 6
·407
·
IF 5.4
Fan Lihua,Ou Zongyuan,Li Fan,Shi Yiheng,Wu Di,Wu Yongning,Li Guoliang
Sensitive and reliable quantification of Ochratoxin A (OTA) in food is essential for ensuring food safety and protecting public health. In this study, a dual-mode colorimetric and Surface-Enhanced Raman Spectroscopy (SERS) biosensor was developed by integrating DNAzyme-responsive hydrogel and Au@Pt@4-MBN nanozyme for signal amplification. Upon introduction of OTA, a specific cascade reaction was triggered, activating the generated DNAzymes and leading to the disintegration of the hydrogel network and the subsequent release of encapsulated nanozymes. The extent of hydrogel disintegration exhibited a positive correlation with OTA concentration, enabling straightforward quantitative detection. The biosensor demonstrated excellent sensitivity, with detection limits of 0.0668 ng mL⁻¹ (colorimetric) and 0.0342 ng mL⁻¹(SERS). When applied to spiked corn samples, it achieved high recoveries of 98.70%-100.93% (colorimetric) and 95.6%-104.27% (SERS), confirming its reliability. The method also demonstrated high practical applicability for authentic non-spiked samples, with a positive detection rate of 10% that was consistent with the results of the national standard method. This robust platform offers significant potential for sensitive mycotoxin monitoring in food and environmental safety. Graphical The alternative text for this image may have been generated using AI.
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ACS Applied Materials & Interfaces
·
2026
·Vol. 18
·期 34
·46680-46690
·
IF 7.8
Xu Jiao,Liu Qiming,Wu Dongxu,Wang Haotian,Tang Huayi,Liu Weili,Liang Hongwei,Yang Yiming
The development of polarization-sensitive photodetectors based on low-dimensional materials with intrinsic lattice anisotropy has paved the way for next-generation polarizer-free and integration-friendly polarization-sensitive optoelectronic devices. Despite their superiority in miniaturization, the relatively low dichroic ratios (DRs) hinder further industrialization. In this work, low-dimensional derivatives of perovskite, quasi-1D yellow-phase (δ-phase) CsPbI 3 single nanowires (NWs) are investigated for polarization-sensitive photodetection. Aberration-corrected transmission electron microscopy (TEM) and angle-resolved polarized Raman spectroscopy (ARPRS) reveal the pronounced crystallographic anisotropy of δ-CsPbI 3 . The pristine δ-CsPbI 3 single NW photodetector exhibits a large DR of up to 8.3 under 405 nm illumination. To overcome the limited optoelectronic performance arising from the indirect bandgap nature of δ-CsPbI 3 , localized surface plasmon resonance (LSPR) is introduced by decorating the δ-CsPbI 3 single NW with Au nanoparticles (NPs) via thermal evaporation. The Au-decorated device exhibits up to approximately 9-fold photocurrent enhancement compared with the pristine one, achieving a photoresponsivity ( R ) of 5.3 mA W –1 and a specific detectivity ( D *) of 1.1 × 10 10 Jones while retaining the high polarization sensitivity. In addition, the Au-decorated device demonstrates appreciable operational stability under ambient conditions, preserving 92% of its initial photocurrent after 400 switching cycles. This work unveils the great potential of the δ-CsPbI 3 single NW for polarized light detection and demonstrates the feasibility of Au NP decoration regarding optoelectronic performance optimization, which can potentially be extended to other low-dimensional perovskite derivatives with analogous quasi-1D chain lattices.
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ANALYTICA CHIMICA ACTA
·
2026
·
IF 6.1
Xiaoxia Han,Dan Li,Yiran Li,Lizhen Huang,Bin Dong,Sui-Dong Wang,Hao Wu
Background Malondialdehyde (MDA) is a pivotal oxidative stress biomarker implicated in cardiovascular diseases, neurodegeneration, and cancer; however, its trace quantification in complex biological matrices remains analytically daunting. Photoelectrochemical (PEC) sensing offers inherently low background noise and exceptional sensitivity for trace bioanalysis. Nevertheless, efficiently translating molecular recognition into amplified PEC signals remains a challenge. Results We report a nanoconfinement-mediated PEC interface that integrates covalent molecular conjugation with plasmonic amplification within a crystalline matrix scaffold. Within this nanoconfined environment, localized Au nanoparticles serve as plasmonic amplifiers that anchor 4-aminothiophenol (4-ATP) receptors. Upon MDA recognition, the optimized sensor exhibits dual linear detection ranges spanning 0.001 to 1.0 nmol L −1 ( R 1 2 = 0.9928) and 1.0 to 1000 nmol L −1 ( R 2 2 = 0.9992), yielding an ultralow detection limit of 0.3 pmol L −1 . Significance The confined Schiff-base reaction between 4-ATP and MDA generates an interfacial reaction product, leading to a new absorption band at approximately 450 nm and modulation of the Au LSPR band. This change is mainly attributed to the altered local dielectric environment around Au NPs. Wavelength-dependent operando transient photovoltage spectroscopy (TPV) provides mechanistic evidence that plasmon-driven hot-carrier injection augments PEC signal output. Overall, this work establishes an interface-engineering paradigm that integrates molecular conjugation with plasmonic coupling, offering a promising blueprint for the PEC detection of small-molecule biomarkers.
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ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Bofei Zhang,Baozhong Zhang,Boxu Chen,Kunfeng Zhang,Yiming Wang,Hanyu Chen,Baoshan He
A ratiometric electrochemical aptasensor was developed for ultrasensitive PFOA detection. • Fc-PtPd@HOF-101 served as the sensing platform and Au@MXene as the signal label. • The sensor achieves an ultralow detection limit of 6.04 fg/mL with excellent linearity from 10 fg/mL to 10 ng/mL. • Fc and MB signals provided self-calibration, improving accuracy and reproducibility. • Validated in real samples: tap, landscape, and PTFE-cooked water from Zhengzhou. Perfluorooctanoic acid (PFOA), as the most representative perfluorinated compound, is a persistent organic pollutant with exceptional chemical stability and resistance to natural degradation. Traditional detection methods, which rely on sophisticated instrumentation, exhibit limited sensitivity and often struggle to meet the requirements for trace-level analysis. In this study, a ratiometric electrochemical aptasensor was developed based on a ferrocene and hydrogen-bonded organic framework co-modified gold electrode (Fc-PtPd@HOF-101) combined with an Au@MXene signal tag, achieving ultrasensitive PFOA detection in water. The sensor utilizes an Fc internal reference and MB response indicator, with DPV detection. Au@MXene/cDNA/MB probe was constructed. In the presence of target PFOA, the sensor forms a stable Apt-PFOA complex, triggering the displacement of complementary DNA and the subsequent release of the signal probe, leading to a decrease in MB signal. The large specific surface area of Au@MXene enables high loading of cDNA and MB, significantly amplifying the signal while Fc remains stable. A ratiometric aptasensor was established using the current ratio I MB /I Fc . Under optimized conditions, the sensor exhibited a linear range of 10.0 fg mL -1 to 10.0 ng mL -1 and a low detection limit of 6.04 fg mL -1 , with outstanding selectivity, reproducibility, and stability. This study provides a novel technical approach for the rapid and sensitive detection of trace PFOA in environmental water samples. Download: Download high-res image (203KB) Download: Download full-size image
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Advanced Optical Materials
·
2026
·
IF 7.2
Jiaqi Qi,Xuanfeng He,Haitao Jiang,Yuhuai Fei,Yinying Cheng,Jing Song,Cong Wang,Donglai Han
Tin-based perovskites are promising lead-free candidates for nonlinear optical applications, yet their performance and stability require further improvement. This work proposes a multi-step interface engineering strategy to markedly enhance the nonlinear optical response. A stable Cs 2 SnI 6 (S-Cs 2 SnI 6 ) film was first prepared via an improved in situ growth method, exhibiting an initial nonlinear absorption coefficient ( β ) of −4.12 × 10 −7 m W −1 . By replacing the conventional liquid crystal 4-Cyano-4’-pentylbiphenyl (5CB) with the π -conjugated liquid crystal 4-[(4-Pentylphenyl)iminomethyl]benzonitrile (5CNB), an S-Cs 2 SnI 6 @5CNB composite was obtained. The optimized interfacial interaction facilitated electron transfer, resulting in a significantly enhanced β value of 2.05 × 10 −6 m W −1 . Further incorporation of plasmonic gold nanoparticles (Au NPs) yielded the Au/S-Cs 2 SnI 6 @5CNB heterostructure. Benefiting from the localized surface plasmon resonance (LSPR) of Au NPs, the local electromagnetic field was substantially intensified, boosting β value to 6.94 × 10 −6 m W −1 , a 239% increase over the composite without Au and a 434% increase over the control without the perovskite. Z-scan measurements confirmed outstanding optical limiting with a low threshold of 0.072 J cm −2 . This study successfully demonstrates a synergistic enhancement strategy, paving the way for advanced optical limiters and nonlinear photonic devices.
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