MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 9
·1-10
·
IF 5.3
Zhao Fan,Liu Yunxi,Lan Jingyue
A simple and efficient dual-signal electrochemical sensor was designed for glyphosate (GLYP) determination based on the one-step electro-synthesized Cu-Hemin MOFs/CNTs nanocrystals. Cu-Hemin MOFs/CNTs were directly modified on the electrode through electrodeposition, avoiding complicated synthesis and modification processes. The incorporation of CNTs greatly boosted the conductivity of Cu-Hemin MOFs and the sensitivity of the electrochemical sensor. Cu active sites in Cu-Hemin MOFs were converted to CuCl, allowing the specific detection of GLYP with the turn of CuCl into non-electroactive Cu-GLYP. Meanwhile, GLYP showed highly effective inhibition effect on the inherent peroxidase-like activity of Cu-Hemin MOFs, therefore generating the second electrochemical signal with Cu-Hemin MOFs-catalyzed o -phenylenediamine ( o -PD) + H 2 O 2 system. The Cu-Hemin MOFs/CNTs based sensor with two electrochemical signals showed good linearities of 1.0 × 10 −10 M − 3.0 × 10 −6 M and 1.0 × 10 −10 M − 5.0 × 10 −5 M, with detection limits of 5.17 × 10 −12 M and 6.81 × 10 −12 M for the CuCl signal based assay and nanozyme catalyzed o -PD + H 2 O 2 procedure, respectively. This simple and robust dual-signal sensor with excellent selectivity, accuracy, and stability allowed GLYP quantification in real samples, highlighting the potential application of this approach for food and environmental monitoring. Graphical Abstract
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Yanke Zhang,Chi Zhang,Wei Chen,Zhengchun Liu
The detection of glucose in beverages is crucial for dietary management and healthcare. Excessive sugar consumption can lead to severe conditions, such as obesity, diabetes, cardiovascular diseases, and cancer. In this study, Cu-embedded laser-induced graphene (Cu/LIG) materials were fabricated for non-enzymatic glucose detection using a simple, direct, and cost-effective laser-patterning method on a Cu 2+ /ethyl-cellulose/polyimide membrane. The experimental results showed that the Cu/LIG electrode exhibited lower charge transfer resistance and a distinct diffusion process compared to the LIG electrode. This improvement can be attributed to the optimized graphene formation achieved by employing ethyl-cellulose (EC) and CuCl 2 as combustion promoters. Under optimal conditions, Cu/LIG-600 demonstrated excellent electrocatalytic activity for glucose oxidation, with a low response concentration (5 μM), fast response time (2.0 s), and detection ranges of 0.005–0.525 mM (I-t) and 0.5–4.0 mM (CV). Moreover, the sensor exhibited high selectivity, stability (retaining over 90 % activity after 28 days), and satisfactory recovery rates for spiked glucose in Cola, Sprite, Black Tea, and sugarless Soda Water, indicating its potential for non-enzymatic glucose detection in beverages.
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APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Xuanqi Hao,Xiao Zhang,Chenchen Liu,Ping Yang
Metal element doping often can improve the photoluminescence (PL) of carbon dots (CDs). In this paper, blue and green emitting CDs (BCDs and GCDs) were synthesized by using phenylenediamine as the carbon and nitrogen sources. Cu-doped CDs (Cu-CDs) were fabricated by using copper acetylacetone as a precursor. The PL peak wavelengths of sample Cu-doped blue CDs (Cu-BCDs) and green CDs (Cu-GCDs) were 450 and 543 nm, respectively. The full width at half maximum of PL spectra were 67.31 and 93.13 nm, the PL quantum yields (PLQYs) were 13.6 and 38.7 %, and the average fluorescence lifetimes were 4.34 and 20.97 ns, respectively. The PL intensity of the Cu-CDs samples was enhanced with the photostability, and thermal stability test results showed that the Cu-CDs samples also had excellent stability. The Cu-BCDs and Cu-GCDs were employed in the field of sensing applications due to their excellent selectivity towards Cr (VI) and tetracycline hydrochloride (TC) detection. The detection limits for Cr (VI) and TC using Cu-BCDs were 0.34 and 0.86 μM, while Cu-GCDs showed detection limits of 0.47 and 0.50 μM, respectively, demonstrating the broad application prospect for Cu-CDs in sensing applications.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Yalin Ran,Junfeng Hu,Yuanyuan Chen,Zhenan Rao,Jichun Zhao,Zhigang Xu,Jian Ming
Nanoscale drug delivery systems derived from natural bioactive materials accelerate the innovation and evolution of cancer treatment modalities. Morusin (Mor) is a prenylated flavonoid compound with high cancer chemoprevention activity, however, the poor water solubility, low active pharmaceutical ingredient (API) loading content, and instability compromise its bioavailability and therapeutic effectiveness. Herein, a full-API carrier-free nanoparticle is developed based on the self-assembly of indocyanine green (ICG), copper ions (Cu 2+ ) and Mor, termed as IMCNs, via coordination-driven and π-π stacking for synergistic tumor therapy. The IMCNs exhibits a desirable loading content of Mor (58.7 %) and pH/glutathione (GSH)-responsive motif. Moreover, the photothermal stability and photo-heat conversion efficiency (42.8 %) of IMCNs are improved after coordination with Cu 2+ and help to achieve photothermal therapy. Afterward, the released Cu 2+ depletes intracellular overexpressed GSH and mediates Fenton-like reactions, and further synergizes with ICG at high temperatures to expand oxidative damage. Furthermore, the released Mor elicits cytoplasmic vacuolation, expedites mitochondrial dysfunction, and exerts chemo-photothermal therapy after being combined with ICG to suppress the migration of residual live tumor cells. In vivo experiments demonstrate that IMCNs under laser irradiation could excellently inhibit tumor growth (89.6 %) through the multi-modal therapeutic performance of self-enhanced chemotherapy/coordinated-drugs/ photothermal therapy (PTT), presenting a great potential for cancer therapy.
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CHEMICAL ENGINEERING JOURNAL
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2024
·
IF 13.3
Ke-Xin Chen,Li-Yin Gao,Zhi-Chao Meng,Zhi-Quan Liu
In this study, nanotwinned Cu nanowires (nt-Cu NWs) with varying twin characteristics were fabricated via pulse electrodeposition using a novel H 3 BO 3 based electrolyte, and their impact on the oxidation process was investigated. The density and direction of twin lamellas within nt-Cu NW were adjusted by modifying the concentration of H 3 BO 3 and the current density. Specifically, the average twinning thickness of Cu NWs increases from 26.7 nm to 424.5 nm as the concentration of H 3 BO 3 increases from 0 g/L to 6 g/L. Moreover, three types of nt-Cu NWs with distinct twinning directions, namely waterfall type, bevel type, and ladder type were fabricated by changing the current density from −0.16 ASD to -1.6 ASD (vs Ag/AgCl). A nanowire Winand (NWW) diagram was established to describe the change of twin density and direction based on the difference between the growth behaviour of thin films and nanowires. The thermogravimetric analysis (TGA) and transmission electron microscopy (TEM) were further used to characterize the oxidation process of nt-Cu NWs. It revealed that the oxide thickness was closely related to the thickness of twin lamellas for the ladder type nt-Cu NWs. Also, the waterfall type Cu NWs exhibited a unique bead-chain like oxide morphology and a slower oxidation rate through the impact on the nanoscale Kirkendall effect (NKE). This study provides valuable insights into the controllable fabrication of nt-Cu NWs and Cu oxide NWs.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2025
·
IF 8.3
Adel Al-Salihy,Jing Hu,Ce Liang,Abdulwahab Salah,Ahmed Bahgat Radwan,Ping Xu
The development of efficient, stable, and cost-effective electrocatalysts is crucial for advancing water-splitting technologies toward sustainable hydrogen production. This study introduces nickel molybdate nanorod-nanoflower (NiMoO 4 NRFs) blends decorated with copper nanodots (Cu NDs) on nickel foam (NF) as a dual electrocatalyst. Under alkaline conditions, the Cu NDs/NiMoO 4 NRFs/NF catalyst demonstrated impressive catalytic performance, requiring only −98 mV overpotential for hydrogen evolution reaction (HER) and 208 mV for oxygen evolution reaction (OER) at 10 mA cm −2 . Tafel slope analysis confirmed efficient kinetics, while impedance spectroscopy and capacitance measurements revealed enhanced charge transfer and abundant active sites. The catalyst demonstrated excellent stability for over 160 h, with improved performance after extended durability tests. It achieved a cell voltage of 1.57 V for overall water splitting at 10 mA cm −2 . Density functional theory (DFT) calculations revealed optimal Gibbs free energy for hydrogen adsorption (ΔG *H = −0.03 eV) and suitable oxygen evolution adsorption energy (ΔG *OOH − ΔG *OH = 2.72 eV), along with a lower water splitting barrier (ΔG b = 0.57 eV), supported by synergistic effects between Cu NDs and NiMoO 4 . Structural characterization confirmed uniform Cu nanodot decoration, enhancing electron transfer. This work presents a scalable, cost-effective approach to high-performance electrocatalysts for sustainable energy.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Yuanqi Yang,Qingqing Xu,Wei Gu,Kaisheng Nan,Siyu Chen,Siling Wang,Jinghai Zhang,Qinfu Zhao
Photodynamic therapy (PDT) has witnessed remarkable progress in recent years owing to its specific properties. Given that the antioxidation system of tumor microenvironment (TME) adversely affects treatment outcomes, powerful TME modulators can significantly resolve the limitation of PDT. Herein, we developed a PEG-modified Cu 2+ -doped hollow mesoporous carbon nanozyme (CHC-PEG) and loaded insoluble photosensitizer IR780 into its pores and cavities to construct the multifunctional nano-system IR780/CHCP. CHC-PEG nanozyme could perform photothermal therapy (PTT) effect and protect IR780 from aggregation-caused quenching (ACQ) effect, while exerting peroxidase (POD)-mimetic activity and the ability of consuming glutathione (GSH) to achieve oxidative stress-augmented PDT effect. When exposed to near-infrared (NIR) light, IR780 was stimulated to produce singlet oxygen ( 1 O 2 ) and CHC-PEG could increase the temperature of TME to exert stronger POD-mimetic activity for producing more hydroxyl radicals ( OH), therefore the IR780/CHCP nano-system exhibited remarkable tumor growth inhibition. Benefited by the enhanced synergistic effect, IR780/CHCP exhibited remarkable in vivo tumor growth inhibition, with the tumor inhibition rate of 93 %, and had no significant effect on major organs. Above all, IR780/CHCP could resist the antioxidant system in TME to enhance the level of oxidative stress, thereby enabling effective anti-tumor therapy. This study introduced a novel strategy to effectively promote the synergistic PTT/PDT effect by the enhanced oxidative stress.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2017
·Vol. 25
·期 4
·3922-3932
·
IF 2.741
Yi Xiaofeng,Yang Meixia,Mo Liuda,Xu Wenkai,Wang Shuai,He Jiarui,Gu Junjie,Ou Minrui,Xu Xiaoping
Copper in drinking water causes a significant environmental problem. Composite material based on alginate hydrogel has been gaining attention in the field of Cu(II) adsorption. However, alginate-based hydrogel exhibits poor mechanical property and relative low adsorption capacity which limit their application. The present study is devoted to the modification of chitosan/calcium alginate/Fe 3 O 4 (CAF) hydrogel microsphere by NaOH solution for enhancement of Cu(II) adsorption. Results reveal that modification of CAF via NaOH solution significantly improves the mechanical strength and Cu 2+ adsorption capacity of pristine materials. FTIR and XRD analysis confirms that CAF and newly prepared materials (NACAF) are successfully prepared. SEM and EDX are employed to analyze the surface morphology and elemental composition, respectively, both before and after their loading with Cu 2+ . XPS study demonstrates adsorption mechanism is based on chelation and ion-exchange. Compressive stress-strain curves demonstrate NACAF has better mechanical performance than CAF. The adsorption kinetics of the two adsorbents follow a pseudo-second-order model. The equilibrium data were best described by Langmuir isotherm model, and the estimated maximum equilibrium sorption capacity, q
m ,is 261.31 mg/g for the NACAF, which is larger than that of CAF (145.39 mg/g). Hence, NACAF shows excellent mechanical strength and high sorption capacity for Cu 2+ . It has great potential for Cu(II) removal in aqueous solutions.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2018
·Vol. 29
·期 7
·5954-5960
·
IF 2.324
Wang Yan,Wang Yishu,Han Jing,Tan Shihai,Guo Fu
Sn grain orientation in solder matrix has recently been considered as one of the principal failure contributions in lead-free solder joints. Since β -Sn exhibits high anisotropy, the differences of electromigration behavior of solder joints with various grain orientations are dramatic. With different angle ( θ ) between the c -axis of Sn grain and the direction of electron flow, the solder joints often demonstrate varying degrees of electromigration-induced damage. The present investigation illustrated significant differences in microstructural features on the surface of Cu reinforced composite solder joints, even with similar angle θ . Two Cu particles reinforced Sn 3.5 Ag composite solder joints with the similar angle θ of 35° and 40° were selected to investigate the effects of Sn grain c -axis on electromigration under high current stressing for 528 h. A large number of Cu 6 Sn 5 compounds were observed and occupied nearly the whole surface with clear polarization effect in one sample. In contrast, very few Cu 6 Sn 5 were found on the surface of the solder matrix in the other sample after current stressing, and the Cu 6 Sn 5 which was formed after reflow disappeared with subsequent current stressing. Even though polarization effect was not obvious, and the cathode interfacial dissolution was observed on such sample. Systematic study revealed that the angle θ alone was not a sole factor to determine the electromigration damage. It has to be considered along with the coordinate system containing the orientation of the c -axis of the Sn grain, a more dominative factor for the diffusing species.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2018
·
IF 3.141
Zihao Zhang,Zehua Pei,Hao Chen,Kequan Chen,Zhaoyin Hou,Xiuyang Lu,Pingkai Ouyang,Jie Fu
Al2O3-supported Cu and Ni monometallic as well as Cu–Ni bimetallic catalysts were synthesized using a coprecipitation method and studied for the in-situ hydrogenation of furfural (FAL) with isopropanol as the solvent and hydrogen donor. The Cu–Ni bimetallic catalysts showed improved activity toward the production of 2-methylfuran (2-MF) and 2-methyltetrahydrofuran (2-MTHF) over that of monometallic catalysts. The results indicated that isopropanol exhibited better performance than methanol for the in-situ hydrogenation of FAL to produce 2-MF and 2-MTHF under the same conditions. The reaction conditions such as the copper–nickel ratios, catalyst loading amount, reaction temperature, and time were optimized. After the reaction was complete, the supported Cu–Ni bimetallic catalyst could be reused four times without a significant loss in catalytic activity.
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Nanomaterials
·
2024
·Vol. 14
·期 24
·2000
·
IF 4.4
Zhipeng Yu,Pengxu Yan,Yilei Sheng,Chengwei Zhang,Zhun Qiao,Qikui Fan,Chuncai Kong,Zhimao Yang
Copper-based materials, renowned for their redox versatility and conductivity, have extensive applications in electrochemical sensing. Herein, we construct stable Cu+/Cu2+interfaces within dual-valence copper nanostructures to achieve enhanced sensitivity in glucose sensing. By employing a hydrolysis method to tune Cu2+/Cu+ratios precisely, we achieved an optimal electrochemical interface with heightened stability and reactivity. The Cu+/Cu2+interface-based flexible electrode demonstrated excellent glucose sensitivity (332.4 µA mmol/L−1cm−2at +0.65 V), wide linear range (up to 10 mmol), a low detection limit of 1.02 nmol/L, and strong selectivity, including detection in human sweat, making this study significant for advanced electrochemical sensors.
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VACUUM
·
2024
·
IF 3.8
Xiu Wen,Zhixiu Yang,Lijing Gao,Ruiping Wei,Xiaomei Pan,Jin Zhang,Guomin Xiao
Electrocatalytic reduction of CO 2 affords a potential way to mitigate the greenhouse effect and fuel crisis. In this work, we compared highly-dispersed CuO nanocomposites and Cu–Cu 2 O nanocomposites which all derived from Cu x Al-LDH for CO 2 electrochemical reduction . The Cu–Cu 2 O based nanocomposites obtained through the restoration strategies still retain its layered structure, simultaneously increasing dual Cu–Cu 2 O active sites, which exhibit excellent performance in selective reduction of CO 2 to C 2 H 4 . The Cu 5 Al-ER obtained through in-situ electrochemical reduction is modified by bulk phase, which can regulate active species, increase surface active sites, enhance C–C coupling. Meanwhile, the electrochemical strategy offers numerous benefits, including gentle conditions, adjustable monitoring, exceptional efficiency and adaptability. We have confirmed that cost-effective Cu–Cu 2 O based nanocomposite derived from Cu 5 Al-LDH can effectively promote C–C coupling during electrochemical CO 2 conversion and improve FE C2H4 . The FE C2H4 of Cu 5 Al-ER reaches 36% at −1.2 V vs. RHE. And the current density reaches −172 mA·cm −2 at −1.6 V vs. RHE. The results showed that compared to Cu 5 Al-LDO, the FE C2H4 of Cu 5 Al-ER increased by 2.6 times. In addition, Cu 5 Al-ER exhibits excellent stability during the 12 hours CO 2 catalytic reduction process.
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