JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
·
2017
·Vol. 82
·期 2
·424-431
·
IF 1.575
Zhang Jing,Liu Mao,Liu Zhijie,Yang Tao,He Qiulai,Yang Kai,Wang Hongyu
Abstract This paper presents the synthesis of a novel core–shell covalently functionalized Fe 3 O 4 coated SiO 2 decorated graphene oxides (Fe 3 O 4 @SiO 2 –GO) adsorbent. The prepared Fe 3 O 4 @SiO 2 –GO was characterized by fourier transform infrared spectrum, X-ray diffraction(XRD), X-ray photoelectron spectroscopy (XPS), and magnetic measurements. And the adsorption properties of the Fe 3 O 4 @SiO 2 –GO toward malachite green were systematically investigated. Various factors possibly affecting the adsorption behavior (initial concentration, contact time, and adsorbent dosage) were also studied in detail. The adsorption capacity (q m ) of Fe 3 O 4 @SiO 2 –GO for malachite green was found to be 265.87 mg/g with best fit to Langmuir isotherm ( R
2 = 0.968), and the adsorption mechanism follows the pseudo-second-order model ( R
2 = 0.981). The results indicate that the Fe 3 O 4 @SiO 2 –GO adsorbent, which is easily separated via an external magnetic field, is a potential low-cost effective material for malachite green removal from contaminated water. Graphical Abstract
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2017
·
IF 2.986
Xiaolin Liu,Yongxin Tao,Huihui Mao,Yong Kong,Jian Shen,Linhong Deng,Linsong Yang
Near-infrared (NIR) light has great potential in biomedical applications due to its advantages of deep penetration depth and low photodamage to biological tissues. In this paper, we constructed a novel core-shell structured drug nanocarrier, Fe 3 O 4 @Au@SiO 2 , for the controlled delivery of etoposide (VP16), a chemotherapeutic drug for cancer patients. The novel core-shell structured drug delivery platform is composed of a mesoporous silica shell and a magnetic Fe 3 O 4 core using Au nanoparticles (AuNPs) as the interlayer, which is characterized by atomic force microscopy (AFM), X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, N 2 adsorption/desorption isotherms and the magnetic measurements with vibrating-sample magnetometer (VSM). The synergistic effects of AuNPs, mesoporous silica and Fe 3 O 4 make the core-shell structured nanocomposites an excellent candidate for targeted and NIR light irradiation-controlled drug delivery. For the proposed nanocarrier of VP16, the mesopores in silica can enhance the encapsulation capacity of the nanocarrier and the AuNPs can effectively convert the NIR light into heat to speed up the drug deliver; meanwhile, the incorporation of Fe 3 O 4 with high magnetization to the drug delivery platform realize drug targeting under an applied external magnetic field.
✓ 已验证
产品关联
DOI
高影响因子
ELECTROANALYSIS
·
2017
·Vol. 29
·期 9
·2098-2105
·
IF 2.851
Fang Shang,Yuan Liu,Sui Wang,Yufang Hu,Zhiyong Guo
An ultrasensitive electrochemiluminescence (ECL) immunosensor for the detection of tetrodotoxin (TTX) is proposed, which are composed of the branched poly-(ethylenimine) (BPEI) functionalized graphene (BGNs)/Fe 3 O 4 -Au magnetic capture probes and luminol-capped gold nanocomposites (luminol-AuNPs) as the signal tag. Herein, a typical sandwich immunecomplex was constructed on the glassy carbon electrode. The BGNs/Fe 3 O 4 -Au hybrids could efficiently conjugate primary antibody via the Au−S chemical bonds or Au−N chemical bonds and rapidly separate under external magnetic field. The introduction of BPEI to GO could enhance the luminol-ECL intensity. Meanwhile, the multifunctional nanocomposites have been proved with good water-solubility, excellent electron transfer, outstanding stability, etc. The luminescent luminol-AuNPs, a high efficient electrochemiluminescence marker, can be assembled on the second antibody, which can produce the ECL signal to achieve the determination of TTX. This proposed ECL immunosensor with a linear range from 0.01–100 ng/mL can be applied in the detection of TTX in real samples with satisfactory results.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2017
·Vol. 17
·期 6
·3880-3887
·
IF 1.483
Liu Xinmeng,Zhao Hongli,Gong Wenxiu,Zhang Zhengcheng,Lan Minbo,Zhao Xueling
In cancer diagnosis and treatment, it is significant to targetedly and efficiently deliver drugs to tumor cells. In our present work, a multifunctional drug delivery system (Fe3O4@mSiO2(TPPS)-PL), pullulan (PL) coated Fe3O4@mSiO2
core/shell nanoparticles with tetraphenylporphyrin tetrasulfonic acid hydrate (TPPS) as a model photodynamic drug, has been designed and prepared. The obtained Fe3O4@mSiO2(TPPS)-PL nanoparticles were discrete and uniformly sized with an average diameter
of 180 ± 10 nm. The cellular uptake of the Fe3O4@mSiO2(TPPS)-PL nanoparticles against HepG2 cells and HeLa cells were evaluated by flow cytometry and confocal scanning laser microscopy (CLSM), respectively. The results indicated that the cellular
uptake of the nanoparticles by HepG2 cells was more than that by HeLa cells due to that HepG2 cells express maximum asialoglycoprotein receptor (ASGPR), and the uptake process was time-dependent. Additionally, the phototoxicity of Fe3O4@mSiO2(TPPS)-PL
nanoparticles against HepG2 cells was investigated by MTT assay, and the materials exhibited efficient phototoxicity. It was suggested that the multifunctional drug delivery system is capable of targeting specific receptors, which is promising for photodynamic therapy (PDT).
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Yanzi Wu,Yujie Ma,Guanhong Xu,Fangdi Wei,Yunsu Ma,Quan Song,Xu Wang,Tang Tang,Yueyue Song,Menglan Shi,Xiaoman Xu,Qin Hu
Artificial enzymes have received much attention because of easy access, low cost and good stability. In this work, we report on a core–shell artificial peroxidase, namely, Fe 3 O 4 @MIL-100(Fe), which can catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by H 2 O 2 to produce a blue product. The combination of Fe 3 O 4 and MIL-100(Fe) can remarkably enhance peroxidase-like activity. The catalytic behavior of Fe 3 O 4 @MIL-100(Fe) followed Michaelis–Menten equation and the affinity of Fe 3 O 4 @MIL-100(Fe) to substrate was higher than horseradish peroxidase. Under the optimal conditions, the absorbance of oxidized TMB at 652 nm is linearly correlated with the concentration of H 2 O 2 . As H 2 O 2 is the oxidative product of cholesterol in the presence of cholesterol oxidase, a sensitive and selective method of cholesterol detection was also developed. As low as 0.8 μM of cholesterol could be detected with a linear range from 2 to 50 μM ( r = 0.999). The proposed method was successfully applied to the detection of cholesterol levels in serum samples. As an artificial peroxidase, Fe 3 O 4 @MIL-100(Fe) has advantages of high catalytic efficiency, low cost, good stability, easy preparation and storage. This work demonstrates that MOF-based materials hold great promise for applications in bioanalysis.
✓ 已验证
产品关联
DOI
高影响因子
Scientific Reports
·
2016
·Vol. 6
·期 1
·1-12
·
IF 5.228
Yin Ting,Huang Peng,Gao Guo,Shapter Joseph G.,Shen Yulan,Sun Rongjin,Yue Caixia,Zhang Chunlei,Liu Yanlei,Zhou Sui,Cui Daxiang
The development of targeted nanoprobes is a promising approach to cancer diagnostics and therapy. In the present work, a novel multifunctional photo/magnet-diagnostic nanoprobe (MNPs-PEG 2K -FA@Ce6) has been developed. This nanoprobe is built using folic acid (FA), bifunctional polyethylene glycol (PEG 2K ) and photosensitizer chlorin e6 (Ce6). The MNPs-PEG 2K -FA@Ce6 nanoprobes are superparamagnetic, can be synthesized on a large scale by a one-pot hydrothermal process without further surface modification and are stable in an aqueous environment for eight months. Compared with free Ce6 nanoprobes in vitro studies, the MNPs-PEG 2K -FA@Ce6 nanoprobes significantly enhance cellular uptake efficiency and promote the effectiveness of photodynamic therapy (PDT) with the assistance of 633 nm laser irradiation. The unique nanoprobes show superior penetration and a retention time of more than six days with less accumulation in the liver allowing highly effective tumor recognition and monitoring. Additionally, there was little damage to healthy organs or tissues. These exciting new nanoprobes could be potential building blocks to develop new clinical therapies and translational medicine.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Su Wang,Jiaxiang Zhang,Kaixuan Ma,Wanyao Zhang,Yan Gao,Pengjie Yu,Shuangfei Zhao,Yirong Feng,Jiming Yang,Ruiyan Sun,Yuguang Li,Ning Zhu,Wei He,Kai Guo
Microreactors excel in nanomaterial preparation but are limited by microchannel clogging for sustained long-term use. This study reports an innovative design of an ultrasound-assisted vortex microreactor for the continuous synthesis of high-performance nano-Fe 3 O 4 particles. Combining visual experiments with computational fluid dynamics (CFD) simulations, four vortex microreactors were designed, and their mixing and heat transfer processes were investigated. Through comprehensive analysis, the microreactor-4 was identified as the optimal configuration, with an optimal flow rate of 1 mL/min and a temperature of 70 °C. By coupling the microreactor with ultrasound, a continuous preparation method for nano-Fe 3 O 4 was realized. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray diffraction (XRD) analyses revealed that the synthesized nano-Fe 3 O 4 particles exhibit a spherical crystal morphology with an average particle size of approximately 6.68 nm, which is 24.4 % and 20.5 % smaller than those prepared by the beaker method and by a stirred-field coupled microreactor reported in the literature, respectively. Vibrating sample magnetometry (VSM) measurements indicated a saturation magnetization of 45.75 emu/g for the nano-Fe 3 O 4 , representing a 32.3 % increase over the beaker method and demonstrating excellent superparamagnetic properties. This study provides a novel and effective pathway for the continuous preparation of nanoscale magnetic materials.
✓ 已验证
产品关联
DOI
高影响因子
DESALINATION
·
2025
·
IF 9.8
Yueyue Jiang,Yu Gong,Chunwen Guo,Xu Xiang
In the face of increasingly scarce freshwater resources, harnessing sustainable solar energy for water evaporation offers an effective pathway to alleviate the water crisis. In this study, we prepared a highly efficient hydrogel solar evaporator (GHCFeP) using graphene oxide (GO), carbon nanotubes (CNTs), nano-Fe 3 O 4 , and polyvinyl alcohol (PVA) as raw materials. The combination of CNTs' excellent molecular thermal vibration effect and nano-Fe 3 O 4 's superior light absorption and photothermal conversion mechanism endows the composite hydrogel with better photothermal conversion capabilities. Meanwhile, the introduction of PVA enhances the water transport capacity within the hydrogel. Furthermore, this work optimizes the three-dimensional (3D) structure of the hydrogel, reducing the “dead evaporation zone” on the evaporator's surface and enhancing the hydrogel's evaporation rate. Due to GHCFeP's low evaporation enthalpy (1377 kJ/kg), under 1.0 sun illumination, its evaporation rate reaches 2.133 ± 0.166 kg·m −2 ·h −1 in pure water and 1.778 ± 0.181 kg·m −2 ·h −1 in simulated seawater. Additionally, by shaping the evaporator into a honeycomb-like structure, the evaporation rate of GHCFeP is further improved. The honeycomb-shaped GHCFeP exhibits an evaporation rate of 2.304 ± 0.042 kg·m −2 ·h −1 in pure water with a photothermal conversion efficiency of 92.4 %, and an evaporation rate of 2.045 ± 0.050 kg·m −2 ·h −1 in simulated seawater. In summary, this work not only develops an efficient solar evaporator but also achieves higher photothermal conversion efficiency through optimized 3D structuring, providing new insights and strategies for related research.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Su Han Wang,Min Lin,Jing Liu,Jian Ping Wang,Ning Peng Wu
The quinolone efflux pump (QepA) protein of a fluoroquinolones-resistant Escherichia coli was grafted on Fe 3 O 4 to synthesize a type of magnetic composite Fe 3 O 4 @QepA. This material was combined with 4 fluorescent tracers to develop a semi-homogeneous fluorescent array on 96-well microplate for determination of fluoroquinolones (FQs) in chicken, and the results were analyzed by using linear discriminant analysis method. Results showed this method could discriminatively determine 15 FQs at the concentration ≥10 ng/g, and could identify each drug species at the concentration ≥2 ng/g. The method exhibited satisfactory recoveries in chicken sample (61.7 %–119.8 %). The analysis results for some unknown samples were consistent with a liquid chromatography mass spectrometry method. This is the first paper reporting a semi-homogeneous fluorescent array for discriminative determination of small molecule substances, and this array can be used as an accurate tool to determine the 15 FQs in meat sample.
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2017
·Vol. 7
·期 10
·317
·
IF 3.553
Rong Guo,Tifeng Jiao,Ruirui Xing,Yan Chen,Wanchun Guo,Jingxin Zhou,Lexin Zhang,Qiuming Peng
Gold nanoparticles (AuNPs) have attracted widespread attention for their excellent catalytic activity, as well as their unusual physical and chemical properties. The main challenges come from the agglomeration and time-consuming separation of gold nanoparticles, which have greatly baffled the development and application in liquid phase selective reduction. To solve these problems, we propose the preparation of polyvinyl alcohol(PVA)/poly(acrylic acid)(PAA)/Fe3O4nanocomposites with loaded AuNPs. The obtained PVA/PAA/Fe3O4composite membrane by electrospinning demonstrated high structural stability, a large specific surface area, and more active sites, which is conducive to promoting good dispersion of AuNPs on membrane surfaces. The subsequently prepared PVA/PAA/Fe3O4@AuNPs nanocomposites exhibited satisfactory nanostructures, robust thermal stability, and a favorable magnetic response for recycling. In addition, the PVA/PAA/Fe3O4@AuNPs nanocomposites showed a remarkable catalytic capacity in the catalytic reduction of p-nitrophenol and 2-nitroaniline solutions. In addition, the regeneration studies toward p-nitrophenol for different consecutive cycles demonstrate that the as-prepared PVA/PAA/Fe3O4@AuNPs nanocomposites have outstanding stability and recycling in catalytic reduction.Keywords:Au nanoparticles;composite materials;catalytic reduction;electrospinning;p-nitrophenol
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF NANOPARTICLE RESEARCH
·
2017
·Vol. 19
·期 10
·1-12
·
IF 2.02
Tian Fei,Niu Libo,Chen Bo,Gao Xuejia,Lan Xingwang,Huo Li,Bai Guoyi
A novel magnetic core-shell nanocomposite Fe 3 O 4 @Chitosan@ZnO was successfully prepared by in situ chemical precipitation method. It has a clear core-shell structure with magnetic Fe 3 O 4 (about 160 nm in diameter) as core, chitosan as the inner shell, and ZnO as the outer shell, as demonstrated by the transmission electron microscopy and the related elemental mapping. Moreover, this nanocomposite has high magnetization (43.6 emu g −1 ) so that it can be easily separated from the reaction mixture within 4 s by an external magnetic field. The introduction of the natural chitosan shell, instead of the conventional SiO 2 shell, and its combination with the active ZnO ensures this novel nanocomposite green character and good catalytic performance in the synthesis of 2-benzimidazoles with moderate to excellent isolated yields at room temperature. Notably, it can be recycled seven times without appreciable loss of its initial catalytic activity, demonstrating its good stability and making it an attractive candidate for the green synthesis of 2-benzimidazoles.
A novel magnetic core-shell nanocomposite exhibited high activity and good stability in the green synthesis of 2-benzimidazoles under mild reaction conditions.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2017
·
IF 3.133
Yan Cheng,Yong Li,Guangbin Ji,Bin Quan,Xiaohui Liang,Zixin Zhao,Jieming Cao,Youwei Du
In this study, an extremely simple one-step ball milling has been applied to fabricate the flaky Fe 3 O 4 /Fe composites. The obtained samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), vibrating sample magnetometer (VSM), and vector network analysis (VNA). It is acknowledged that the ball-milling process has huge influence on the morphology and electromagnetic absorption capability. Compared with the raw Fe 3 O 4 , the saturation magnetization of Fe 3 O 4 /Fe composites improved greatly. When the thickness is just 1.25 mm, the reflection loss values below −10 dB can be achieved from 13.8 to 18 GHz, with a maximum reflection loss of −25.9 at 16.1 GHz. Obviously, the Fe 3 O 4 /Fe composites can be used as magnetic microwave absorbers due to its simple synthesis for the mass production standards. Moreover, this study also gives new enlightenment to design other magnetism/magnetism composites that can be applied to Ku-band such as satellite communications.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）