Food Bioscience
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2025
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IF 5.9
Jia Liu,Bin Yang,Shiyue Niu,Xin Liu,Xian Wang,Liqian Niu,Shuyun Bi
At present, the application range of tetracycline (TCs) is very wide, and excessive residue will pose a threat to the health of consumers. However, there is a lack of methods more suitable for on-site detection. In order to ensure food safety, CdS@ZnS QDs and zeolitic imidazolate framework-8 (ZIF-8) were hybrid to obtain the composite CdS@ZnS QDs@ZIF-8, which was used as fluorescent probe to establish real-time methods for the detection of minocycline (MC) and doxycycline (DC). The quantum yield (QY) of the prepared composite CdS@ZnS QDs@ZIF-8 was 20.76 %. The MC/DC quenched the fluorescence of CdS@ZnS QDs@ZIF-8 in a static manner, which was confirmed by Stern-Volmer and time-resolved fluorescence analysis. The binding constant at 293 K was obtained and electrostatic force was found to play a leading role in the two binding processes. The optimal pH, contact time and temperature for the determinations were obtained. The interferences of some common metal ions, glucose, BSA, DNA, HSA and tryptophan on the detections were investigated. The linear relationship between the concentration of MC/DC and the fluorescence intensity ratio was established. The limits of detection (LODs) were 10.06 and 11.24 ng mL −1 (3 S 0 / S ) for MC and DC. The methods were successfully applied to the detection of MC and DC in egg samples with good recovery and precision.
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CHEMICAL ENGINEERING JOURNAL
·
2024
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IF 13.3
Yi Shao,Hao Suo,Shuting Wang,Yaou Peng,Xiaoying Chu,Ziyue Long,Kanghui Du,Lili Su,Xinyue Sun,Xinyi Wang,Qingying Wang,Renlong Li,Bailiang Wang
Eye trauma, ophthalmic surgery and contact lens (CL) wearing cause corneal infection and bacterial biofilms formation, which further lead to corneal ulcer and perforation. In view of the low bioavailability of antibiotic eye drops and the clinical problems that cause bacterial resistance, we used pH sensitive zeolitic imidazolate framework-8 metal–organic frameworks (ZIF-8 MOFs) to load broad-spectrum antibacterial drugs levofloxacin (LEVO). After the surface modification by hyaluronic acid (HA), the nanomaterial surface was negatively charged. A simple amination treatment was used to endow CL surface with amino groups to combine the negatively charged nano drug loading system through electrostatic forces. The bacteriostatic ring of ZIF-8@LEVO@HA-PEI modified CL (ZLHP-CL) was 34 mm, which could be owing to the high drug loading capacity of ZIF-8 (0.65 mg/cm 2 ). The bactericidal function was further confirmed by shake flask method and live/dead bacterial staining assay against S. aureus , S. epidermidis and E. coli . It is worth mentioning that ZLHP-CL showed significant pH sensitivity to the bacterial infection, which released drug rapidly at pH 5.5 and hardly released drug at pH 7.4. In the bacterial biofilm’s formation experiment, it was found that ZLHP-CL obviously inhibited bacterial adhesion and biofilms formation. Furthermore, it was proved in infectious keratitis animal that ZLHP-CL could kill the bacteria and reduce the inflammation reaction, which showed advantages in corneal tissue repair and light transmittance maintenance. In this work, based on nanotechnology, a facile CL drug loading technology is developed, which can be used to sustained release of various drugs for ophthalmic diseases treatment.
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CHEMICAL ENGINEERING JOURNAL
·
2024
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IF 13.3
Hanhan Lv,Daniel K. Macharia,Zixiao Liu,Lisha Zhang,Chiyan Yu,Chihao Lu,Huansheng Liu,Yumei Zhang,Zhigang Chen
Photothermal catalysis has attracted increasing attention due to the efficient utilization of sustainable solar energy and high catalytic activity. However, its practical application is still limited due to the complex synthesis and low surface area of photothermal materials, as well as the challenges of distinguishing the effects of hot electrons and localized heating. To solve these issues, ZIF-8 derived porous carbon (ZPC) nanocrystals were constructed as high surface area photothermal materials and then decorated with Au nanoparticles as the catalytic components. Au/ZPC nanocomposites are prepared by the assembly of ZIF-8, the pyrolysis and in-situ Au reduction process. They are composed of rhombic dodecahedron-shaped ZPC with an average diameter of ∼120 nm, where Au nanoparticles (2–8 nm) are dispersed well on the surface or within the pore structure of ZPC . Besides, Au/ZPC exhibits a wide range of light absorption between 200 and 1100 nm and high photothermal efficiency of 45 %. With 4-nitrophenol (4-NP) reduction reaction as a model system, Au/ZPC catalyst exhibits a 2-fold increase in the rate of 4-NP reduction when exposed to an 808 nm laser irradiation, in comparison to thermocatalysis at the same temperature. Furthermore, the activation energy for the reduction of 4-NP via photothermal catalysis was much lower than that of thermocatalysis (74.16 vs. 104.26 kJ mol −1 ). By excluding hot electrons effects by transient absorption (TA) spectra, we can establish that the increase of photothermal catalysis rate should result from the localized heating which can decrease the energy barriers for the reduction of 4-NP. Additionally, Au/ZPC displays high stability and maintains remarkable activity even after five cycles. This study may provide some new perspectives for the design and development of efficient photothermal catalysts.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2024
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IF 4.9
Lan Zhang,Tingting Zhang,Shiying Wu,Lujie Li,Wei Li,Lingling Wang,Weihua Li,Xianhuai Huang,Jiansheng Li,Rui Lu
Although surface-enhanced Raman scattering (SERS) is a powerful spectral analysis technique, its practical application is restricted due to the poor chemical stability of some noble metal nanoparticles. In this work, Ag@ZIF-8 nanocomposites with different ZIF-8 core-shell thicknesses were prepared by coating AgNP surfaces with polyvinylpyrrolidone and adjusting the dosage of zinc nitrate and 2-methylimidazole. Several characterizations have confirmed that the Ag@ZIF-8 nanocomposites was successfully prepared. Based on transmission electron microscopy images and SERS spectral intensity, it was determined that Ag@ZIF-8 nanocomposites with a ZIF-8 shell thickness of 30 nm exhibited optimal SERS performance. As a result of evaluating the uniformity and stability of the composite with 4-ATP as the probe molecule, it showed a relative standard deviation of 6.91 % and a decrease in SERS intensity of 4.5 % after 28 days. Based on the results obtained with Ag@ZIF-8 nanocomposites as the SERS substrate, the detection limits of 4-mercaptopyridine and thiram were as low as 5.87×10 −9 M and 6.61×10 −8 M, respectively. Furthermore, the finite-difference time-domain simulation reveals an enhancement factor of 2.6×10 6 , which is in good agreement with the experimental value of 1.8×10 6 , confirming its effectiveness as a SERS substrate.
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TALANTA
·
2024
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IF 5.6
Wenyan Zeng,Qingyuan Jiang,Chaofan Ruan,Wang Ni,Changchang Zhu,Xueling Zeng,Xuan Shi,Rongke You,Ning Ma,Fang-Chang Tsai
The emergence of stimuli-responsive fluorescence anti-counterfeiting technology has garnered increasing attention in the era of intelligent internet. Smart fluorescent hydrogels combine the characteristics of luminous materials with the unique structure of hydrogels, offering the potential for dynamic reversible erasing and multi-tiered data encryption. In this work, a fluorescent hydrogel was constructed by zeolitic imidazolate framework-8 loaded with fluorescein and then mixed with polyvinyl alcohol hydrogel, sodium carboxymethyl cellulose and borax, which could be used for image hiding in visible light. The reversible bonds cross-linked fluorescent hydrogel was stretchable and self-healing with a three-dimensional network structure. The hydrogel presented bright green fluorescence under 365 nm UV light, which was quenched by adding copper ions. Meanwhile, the imprint of the hydrogel could be cleared by L-Cysteine and repeatedly recorded information many times. The alkali-induced shape memory capability was further utilized to achieve multi-tiered data encryption by deforming it to a 3D-specific shape through folding. The rewritable and multi-dimensional encrypted hydrogel is expected to improve data security and reduce resource consumption.
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PubMed
高影响因子
Small
·
2025
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IF 12.1
Hao Li,Zhihao Zhang,Dingding Zhu,Huiyuan Zheng,Zhongze Zhu,Nana Shen,Zhu Guo,Xiaolin Wu,Xiaoying Qi,Qiang Li,Qingming Ma,Hongfei Xiang
Low back pain (LBP) resulting from sciatic nerve compression presents major challenges in pain management, as traditional therapies provide only short-term relief and pose risks of systemic toxicity. In this study, an innovative Fe 3 O 4 @ZIF-8-RVC (FZR) dual-responsive nanoplatform is introduced that integrates magnetic targeting with pH-sensitive, sustained drug release to overcome these limitations. The FZR nanoplatform encapsulates ropivacaine (RVC) within the ZIF-8-coated Fe 3 O 4 core, enabling precise and prolonged analgesia at the injury site through magnetic guidance and acid-triggered release. In vitro and in vivo assessments indicate that FZR achieves high drug loading, sustained release in acidic environments, and excellent biocompatibility, significantly extending analgesic effects in chronic nerve injury models while minimizing systemic exposure. Behavioral tests and molecular analyses in LBP rat models confirm that FZR effectively suppresses pain-related neuronal activity and central sensitization markers. This dual-responsive nanoplatform FZR offers a safe, long-lasting, and targeted therapeutic approach, holding strong potential for advancing pain relief in LBP and related neuropathic pain conditions.
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PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
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IF 8.1
Qingdi Mu,Lujie Sheng,Shuhui Chen,Yuanfa Liu,Maicun Deng,Jizhong Ren
Defect engineering of metal organic frameworks (MOFs) is an emerging effective approach for manipulating their microporosity structure. They are very promising but challenging to achieve significant gas separation performance improvements for mixed matrix membranes (MMMs) fabrication. Herein, we propose a novel thermal induced in-situ defect engineering strategy of ZIF-8 in MMMs by carefully post controlled annealing (above polyimide matrix T g and below ZIF-8 T d ). Attractively, the thermal-triggered polyimide matrix (P84 HT) crosslinking repairs interfacial voids between ZIF-8 and P84 HT. The resulting advanced MMMs exhibit more gas sorption sites and diffusion pathways owing to the missing Zn-N bond of ZIF-8, while exciting enhancement of H 2 /CH 4 and H 2 /N 2 separation performance is obtained compared with the pristine P84 HT membrane. Furthermore, after in-situ defect engineering at 400 °C, the H 2 permeability of the advanced MMMs with 20 wt% ZIF-8 loading is 123.8 Barrer, 19.4 times higher than the pristine P84 HT membrane (6.4 Barrer), while the H 2 /CH 4 and H 2 /N 2 selectivity almost remains essentially unchanged. More importantly, this facile but very effective method demonstrates a new direction to regulate structure of polyimide/MOFs based MMMs for gas separation.
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MICROCHEMICAL JOURNAL
·
2025
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IF 5.1
Lei Zhang,Zhen Zhao,Hongming Zhang,Wanli Jiao
To detect trace hydrogen sulfide (H 2 S) safely, more sensitively and less expensively, a new synthesized ZIF-8-derived ZnO-supported Ag nanoparticle assemblies have been investigated. In the successful formation, ZIF-8 was synthesized in room temperature aqueous solution, followed by ultrasonication to produce Ag + /ZIF-8 compounds, and yielded Ag/ZnO assemblies after sintering. Various characterizations have been done to confirm the morphology, surface chemical state and electron distribution by XRD, SEM, XPS, BET and DRIFT. The sensing test results indicate that at an exciting operating temperature of 100 °C, the A-2 labeled sensor exhibits excellent H 2 S detection capabilities, including a response value of 104 for 2.5 ppm H 2 S, the minimum detection limit of 1.1 ppb, satisfied selectivity, significant resilience against humidity and long time stability. More significantly, a valuable test of 140 h real time detection of the H 2 S emission from fresh fish meat has been performed successfully, providing effective data for protein spoilage assessment. Rhombic dodecahedron structure, catalysis of Ag nanoparticles and overflow effect of H 2 S result in the distinct sensing mechanism, providing novel insights and theoretical foundations for developing highly efficient trace H 2 S gas sensors.
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POLYMER
·
2024
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IF 4.1
Hongnan Zhang,Taoyuan Liu,Ke Li,Xiaohong Qin
Nowadays, modern industries are rapidly developing, which is caused by a significant amount of high-temperature exhaust gases in the atmosphere, and it contains complex pollutants, formaldehyde, solid particles, and harmful gases that are discharged. For this scenario, the conventional filtering materials are challenged for prevention of high-temperature exhaust gas formaldehyde volatilization because they are composed of metal and inorganic materials caused by oxidation-prone and resilient wear. A recently introduced technique to fabricate composite nanofiber membranes with high strength, modulus, efficiency, low resistance for high-temperature exhaust gas filtering, and its capability to adsorb formaldehyde was discussed in this study. Initially, Polyamide acid (PAA) solution and silicon dioxide (SiO 2 ) nanomicrospheres are used as raw materials for producing electrostatic and thermal imidization Polyimide (PI/SiO 2 ) nanofiber membranes (NFMs) in co-spinning processes. Furthermore, zeoliticimidazolate framework-8 (ZIF-8) was transferred into PI/SiO 2 NFMs and produced the PI/SiO2@ZIF-8 NFM. These findings show that adding SiO 2 nanomicrospheres reduced the fiber packing density as well as air filtration resistance, and PI/SiO2@ZIF-8 NFMs achieve up to 99.703% filtration efficiency and maintain a pressure drop of 178.7 Pa. The weight loss rate is only 4% at temperatures above 300 °C, and the heat resistance is outstanding. Moreover, the PI/SiO2@ZIF-8 NFMs demonstrate a good formaldehyde adsorption performance with a saturation adsorption capacity for formaldehyde within 4 hours of 41.58 mg/g, which is more than 12 times that of the PI/SiO2 NFMs without ZIF-8.
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高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2024
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IF 4.8
Changfeng Zeng,Jie Li,Jie Gong,Lixiong Zhang,Liang Yu
ZIF-8/PVA microspheres with an even size were synthesized with the assistance of a simple microfluidic device. The ZIF-8/PVA microdroplets were first generated in a simple co-flow microfluidic device using a PVA aqueous solution dispersed with ZIF-8 nanoparticles as the dispersed phase and fatty acid methyl ester (FAME) as the continuous phase. Subsequently, the ZIF-8/PVA microdroplets were further extracted to form ZIF-8/PVA microspheres. The influence of the type of continuous phase on the sphericity of microspheres was investigated and the effect of ZIF-8 content was studied. Further studies showed that decreasing the extraction rate and using additives of NaCl in the dispersed phase could improve the sphericity of the ZIF-8/PVA microspheres. Finally, the synthesized ZIF-8/PVA microspheres were used to study the loading and release of tetracycline. The results showed that the loading of ZIF-8/PVA microspheres was more than 5 times higher than that of pure PVA microspheres. The drug release time of ZIF-8/PVA microspheres was much longer than that of the PVA microspheres and the release rate was significantly affected by the pH of the environment.
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高影响因子
Frontiers in Bioengineering and Biotechnology
·
2025
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IF 4.8
Xiping Jiang,Hui Xu,Xinyue Sun,Xuefan Yang,Yuxuan Xia,Wen Xue,Yaohua He
Introduction: The high rate of retear following rotator cuff repair is largely attributed to the absence of a fibrocartilage layer and limited bone regeneration capacity. We aim to evaluate a bioadhesive derived from decellularized porcine annulus fibrosus extracellular matrix, loaded with zeolitic imidazolate framework-8 (ZIF-8), and to promote rotator cuff tendon–bone healing.Methods: Three adhesive formulations were developed: (1) silk fibroin/tannic acid (ST group), (2) ST combined with decellularized porcine annulus fibrosus extracellular matrix (ST/dECM group), and (3) ST/dECM supplemented with ZIF-8 (ST/dECM/ZIF-8 group). Optimal component ratios were determined using lap shear strength testing. The microstructure, Fourier transform infrared (FTIR) spectra, swelling behavior, and degradation properties of the materials were characterized. In vitro studies assessed the adhesives’ effects on cytotoxicity, proliferation, and the chondrogenic and osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells (BMSCs). A rat rotator cuff repair model was used to evaluate in vivo anti-inflammatory effects, fibrocartilage and bone regeneration, and biomechanical performance.Results: All adhesive formulations exhibited comparable tissue adhesion strength and biocompatibility. Both the ST/dECM and ST/dECM/ZIF-8 groups enhanced BMSC chondrogenic differentiation compared to the ST group, with the ST/dECM/ZIF-8 group showing superior osteogenic induction. In vivo, the ST/dECM/ZIF-8 hydrogel effectively reduced interfacial inflammation and promoted fibrocartilage and bone regeneration. Biomechanical testing demonstrated significantly higher ultimate load, tensile stress, and stiffness in all adhesive-treated groups compared to untreated controls.Conclusion: The ST/dECM/ZIF-8 bioadhesive hydrogel promotes fibrocartilage and bone regeneration. These findings highlight its potential as a promising biomaterial-based strategy to enhance tendon-to-bone interface healing following rotator cuff repair.
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
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IF 9
Bingbing Yuan,Shuang Yuan,Chaozheng Jia,Ping Hu,Siheng Zhao,Xiaozhuan Zhang,Zewen Xu,Lihong Liu,Meng You,Shengchao Zhao,Kuo Chen,Dongxiao Yang,Juhui Jiang,Xiangdong Lou,Jianxun Dong,Tatiana V. Plisko,Q.Jason Niu
To address the growing global challenge of water scarcity, developing high-performance reverse osmosis (RO) membranes for desalination and water purification is essential. However, conventional polyamide (PA) thin-film composite (TFC) membranes are limited by the trade-off between permeability and selectivity, as well as limited rejection of small-molecular contaminants. In this study, we report a novel high-permeability thin-film nanocomposite (TFN) RO membrane by tuning the hydrophilicity of a zeolitic imidazolate framework-8 (ZIF-8) interlayer to achieve synergistic enhancement in both desalination and micropollutant removal. Specifically, a ZIF-8 interlayer was in situ grown on a hyperbranched PA-UIO-66-NH 2 support, followed by partial ligand exchange with 5,6-dimethylbenzimidazole (Hdmbim) to reduce its hydrophilicity. This modification facilitated the diffusion of m-phenylenediamine (MPD) monomers, enabling the formation of a highly cross-linked PA selective layer (h-TFN) with angstrom-scale water transport channels. The optimized h-TFN membrane exhibited a water permeability of 5.40 L·m −2 ·h −1 ·bar −1 , 2.94 times that of the control TFC membrane, while maintaining high NaCl rejection (98.35 %). Moreover, it achieved 96.06 ± 0.18 % rejection for micropollutants such as heptyl paraben (HP). These results surpass the permeability–selectivity limitations of existing membranes and demonstrate a promising strategy for the design of advanced RO membranes capable of efficient desalination and micropollutant removal.
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