ADVANCED FUNCTIONAL MATERIALS
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2018
·
IF 13.325
Li Jing,Yin Ruiming
In this study, self-reinforced Y-α-SiAlON was prepared by two-step phase transformation using single or dual rare-earth oxide addition. The process was implemented by a two-step sintering technique. The mechanism of two-step phase transformation and microstructure evolution of Y-α-SiAlON with or without Ce 2 O 3 addition were investigated in detail. The predominant phase of the sample after the first step (i.e., pressureless sintering at low temperature) comprised elongated β-SiAlON grains. By contrast, the majority phase of sample after the second step (i.e., gas pressure sintering at high temperature) included coarse, elongated α-SiAlON grains. The driving force for β-to-α SiAlON phase transformation and liquid viscosity decreased, whereas the amount of liquid phase increased because of Ce 2 O 3 addition, which contributed to anisotropic growth and resulted in more elongated α-SiAlON grains. The sample co-doped with Y and Ce exhibited the best mechanical properties with fracture toughness of 7.8 MPa m 1/2 and Vickers hardness of 19.81 GPa.
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高影响因子
ACS Applied Electronic Materials
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2020
·
IF 0
Zhi Wang,Yulan Han,Jing Liang,Haoliang Huang,Chuansheng Hu,Ping Liu,Junxiang Xiang,Zeming Qi,Yalin Lu,Kaihui Liu,Jun Jiang,Bin Xiang
Hydrogenation plays a critical role in tuning the material structural phase that fundamentally determines their electronic, optical, magnetic, and catalytic properties. However, prevailing hydrogenating techniques rely on noble-metal catalysis, high-temperature/pressure conditions, and high-energy proton implantation. Here, we report an optically controlled hydrogenation strategy of atomic-layered material α-MoCl3 via laser illumination treatment in a moist atmosphere environment. With the assistant of laser, hydrogens are generated from the reaction between water molecules and highly electronegative element chlorine, intercalate into α-MoCl3, and ultimately produce a more conductive phase with a maximum hydrogen-doping density of 0.04 wt %. Without laser, hydrogens are reversibly released and the structure restores to pristine α-MoCl3. Density-functional theory studies reveal the facile mechanism of α-MoCl3 hydrogenation including the dependence on the laser wavelength and power, the concomitant electronic phase transition, and improved material stability. Our results provide a plausible way for hydrogenating low-dimensional materials through precise control of laser treatment, which can find its multifunctional applications in hygrometer, photodetector, and photocontrollable smart devices.
研究领域:
材料科学
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纳米技术
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光电子学
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物理化学
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凝聚态物理
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DOI
COMPOSITES PART B-ENGINEERING
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2019
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IF 6.864
Tian Liu,Xingrong Zeng,Xuejun Lai,Hongqiang Li,Tongyi Wu
Novel platinum nanoparticles immobilized on exfoliated α-zirconium phosphate (Pt@ZrP-E) was prepared and the structure of Pt@ZrP-E was characterized by SEM, TEM and XRD . The effect of Pt@ZrP-E on anti-tracking and erosion properties of Pt@ZrP-E/SiR was investigated. It was found that Pt@ZrP-E can be uniformly dispersed in SiR and SiR containing 0.3 ph Pt@ZrP-E could pass 1A 4.5 kV level. TG results showed that the residues of Pt@ZrP-E/SiR with 0.3 ph Pt@ZrP-E at 700 °C increased from 43.4 wt% to 54.0 wt% compared to SiR. According to the thermogravimetry-Fourier transform infrared spectroscopy (TG-FTIR) results, the release of carbonyl compounds of Pt@ZrP-E/SiR was decreased but that of CH 4 was significantly increased, indicating that Pt@ZrP-E was capable of inhibiting the oxidation of methyl groups and facilitate the cross-linking of SiR under high temperature, which results in the formation of a protective ceramic layer , reduce the ablation from electrical arcing and improve the anti-tracking and erosion properties of SiR.
研究领域:
材料科学
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聚合物纳米复合材料
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电气绝缘材料
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高影响因子
CARBOHYDRATE POLYMERS
·
2026
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IF 12.5
Junhao Ye,Ruiquan Hou,Kang Xie,Guangmin Ou,Zhixiang Zhang,Dongmei Cheng
The plant-derived photoactivated fungicide α-Terthienyl (α-T) exerts antimicrobial effects through light-induced reactive oxygen species generation. However, its agricultural application has been constrained by poor targeting capability and low photostability. To address these challenges, we developed a dual-responsive nanoparticle delivery system (α-T NPs) based on a pectin-chitosan polymer network that specifically recognizes the acidic and pectinase-rich microenvironment created by Botrytis cinerea hyphae secretions. Controlled release studies demonstrated that both acidic conditions (pH 5.0) and pectinase exposure substantially promoted α-T release, achieving cumulative release rates of 71.73% and 74.49% respectively over 60 h. The nanoparticle system showed no adverse effects on healthy tomato leaf growth while forming a protective barrier that effectively suppressed fungal infection. Targeted delivery significantly enhanced fungicidal efficacy, with α-T NPs exhibiting an EC₅₀ of 0.419 mg/L compared to 1.943 mg/L for α-T (technical material, TC). Confocal microscopy and quantitative analysis confirmed the enhanced targeting mechanism, revealing substantially stronger fluorescence intensity and higher α-T accumulation specifically on treated fungal hyphae. Additionally, α-T NPs significantly improved photostability, extending the half-life by approximately 1.93-fold under continuous illumination compared to α-T (TC). This work establishes an innovative “pathogen-activated” delivery platform with promising applications in sustainable crop protection.
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DOI
PubMed
高影响因子
IUCrJ
·
2020
·Vol. 7
·期 3
·422-433
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IF 5.401
Shi P.,Xu S.,Ma Y.,Tang W.,Zhang F.,Wang J.,Gong J.
Herein the nucleation pathway of conformational polymorphs was revealed by studying the relationships and distinctions among a series of α,ω-alkanedicarboxylic acids [HOOC–(CH2)n−2–COOH, named DAn, where n = 5, 7, 9, 11, 13, 15] in the solid state and in solution. Their polymorphic outcomes, with the exception of DA5, show solvent dependence: form I with conformation I crystallizes from solvents with hydrogen-bond donating (HBD) ability, whereas form II with conformation II crystallizes preferentially from solvents with no HBD ability. In contrast, form II of DA5 does not crystallize in any of the solvents used. Quantum mechanical computation showed that there is no direct conformational link between the solvents and the resultant polymorphic outcomes. Surprisingly, solute aggregates were found in no-HBD solvents by Fourier transform infrared spectroscopy, and only monomers could be detected in HBD solvents, suggesting stronger solvation. Furthermore, it was found that all six compounds including DA5 followed the same pattern in solution. Moreover, crystal-packing efficiency calculations and stability tests stated that dimorphs of DA5 bear a greater stability difference than others. These suggest that the rearrangement from conformation II to I could not be limited by hard desolvation in HBD solvents, where form I was also obtained. In other systems, metastable II was produced in the same solvents, probably as a result of the rearrangement being limited by hard desolvation. In this work, a comparative study uncovers the proposed nucleation pathway: difficulty in desolvation has a remarkable effect on the result of rearrangement and nucleation outcome.
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高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2026
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IF 3.9
Leiting Kuai,Xuan Meng,Naiwang Liu,Li Shi
This study aims to elucidate the reaction mechanism of naphthalene alkylation with long-chain α-tetradecene (α-C14H28) over H-FAU zeolite, a reaction critical for producing high-value alkylated aromatics in industrial catalysis. By combining in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) with kinetic and thermodynamic analysis, this study quantitatively tracks the evolution of four key carbocation intermediates formed on distinct Brønsted acid sites and identifies the Wheland-intermediate-forming step as rate-determining. For the first time, adsorption and diffusion analysis, reaction kinetics, and comprehensive catalyst characterization (XRD, NH3-TPD, pyridine-IR) are integrated to establish a complete mechanistic pathway. The results reveal how pore confinement and acid-site distribution govern intermediate evolution and overall activity, thereby offering a validated model for the rational design of selective and stable zeolite catalysts for continuous alkylation processes.
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高影响因子
International Journal of Pharmaceutics-X
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2026
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IF 7.9
Sai Gao,Ruili Yin,Jingxuan Shi,Zhuang Miao,Longyan Yang,Dong Zhao
Psoriasis is a chronic immune-mediated inflammatory skin disease characterized by keratinocyte hyperproliferation and cytokine-driven immune activation, in which TNF-α plays a central pathogenic role. We developed a layered hydrated silk fibroin (SF) microneedle system (ETA@Hyd MN) with SF tips loaded with etanercept (ETA, a TNF-α inhibitor for psoriasis), for local cutaneous delivery to reduce systemic exposure and rapidly dissolving polyvinyl alcohol (PVA) bases that facilitate retention of the SF tips within the skin. Hydration markedly slowed ETA release, with approximately 80% released at 48 h compared with approximately 75% released within 1 h from microneedles without hydration. In HaCaT cell scratch assays, release media from ETA@Hyd MN attenuated the accelerated wound closure response, resulting in a greater remaining scratch width than that in the model group at 48 h. In an IMQ-induced psoriasis-like mouse model, ETA@Hyd MN improved clinical symptoms, reduced PASI scores, alleviated spleen enlargement, and suppressed epidermal hyperplasia and TNF-α/IL-6 expression. These results demonstrate that ETA@Hyd MN enables sustained ETA release and effectively suppresses inflammation, highlighting its potential for treating inflammatory skin diseases. Download: Download high-res image (190KB) Download: Download full-size image
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高影响因子
Frontiers in Cellular and Infection Microbiology
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2026
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IF 5.5
Yujuan Li,Yi Yang,Ting Zhou,Jing Zhou,Jie Hu,Shuangshuang Liang,Zhenhua Xie,Qing Cheng,Yachao Jiang,Chao Jiang,Qing Liu
Amid the growing antibiotic resistance crisis, colistin remains a last-line therapeutic option for multidrug-resistant (MDR) Gram-negative bacterial infections. However, the emergence and rapid dissemination of plasmid-mediated colistin resistance gene (mcr) have markedly reduced its clinical effectiveness. Utilizing colistin adjuvants to restore its antibacterial potency is a promising strategy to combat this threat. In this study, we aimed to investigate the synergistic effects of α-terpineol in combination with colistin against colistin-resistant MDR Escherichia coli (E. coli) and to elucidate the underlying mechanisms of this synergy. In vitro synergistic activity was evaluated using checkerboard microdilution assays, time-kill curve analyses, and resistance development studies. Mechanistic insights were obtained through transcriptomic analysis and fluorescence-probe based assays. In vivo efficacy was validated using Galleria mellonella and mouse acute peritonitis infection models. The results showed that the combination of α-terpineol and colistin exhibited synergistic bactericidal activity and suppressed the development of colistin resistance. α-Terpineol increased inner- and outer-membrane fluidity in E. coli, thereby enhancing colistin uptake. Furthermore, it inhibited superoxide dismutase (SOD) activity, preventing the conversion of O2·– to H2O2 and causing superoxide accumulation. Elevated O2·– levels damaged iron–sulfur clusters and impaired respiratory function. Together with the proton motive force (PMF) dissipation, these effects severely impaired ATP synthesis, ultimately sensitizing MDR E. coli to colistin. The combination also showed significant therapeutic efficacy in animal models. Our findings identify α-terpineol as a promising colistin adjuvant that restores antibacterial activity by disrupting membrane integrity and impairing antioxidant defenses, offering a viable strategy for treating MDR Gram-negative bacterial infections.
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PubMed
高影响因子
GREEN CHEMISTRY
·
2020
·Vol. 22
·期 21
·7552-7559
·
IF 9.48
Bing-Cai He,Chao Zhang,Pei-Pei Luo,Yu Li,Tong-Bu Lu
Photocatalytic CO2 reduction coupled with water oxidation provides a fascinating approach to mitigating the issues of global warming and energy shortage. Herein, a direct Z-scheme heterojunction of Co1-C3N4@α-Fe2O3 comprising a g-C3N4-supported single-atomic Co site catalyst (denoted as Co1-C3N4) and α-Fe2O3 nanorod arrays is fabricated for efficient CO2 reduction. A CO production rate of 14.9 μmol g−1 h−1 with a high CO selectivity (>99%) is achieved under visible-light irradiation without any sacrificial agents other than water. Time-resolved photoluminescence (TRPL) analysis reveals that both the Z-scheme mechanism and the single-atomic Co sites contribute to the prolonged lifetime of the photo-induced excitons. Moreover, the formation of the Z-scheme heterojunction would lead to an altered charge density of the single-atomic Co sites. In situ diffuse reflectance infrared Fourier-transform spectroscopy and anion adsorption measurements reveal that the key intermediate CO2− could be efficiently stabilized by the positively charged Co sites in Co1-C3N4@α-Fe2O3, thus enhancing the CO2 reduction performance. This work offers a new direction for the rational design of single-atomic site catalysts in artificial photosynthesis.
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高影响因子
ANALYTICAL SCIENCES
·
2023
·Vol. 39
·期 7
·1171-1178
·
IF 1.6
Wang Kun,Gao Xue,Chen Jianfeng,Yang Xiaoyan
Abstract In this study, a sensitive photoelectrochemical immunosensor with dye-enhanced anodic photocurrent response was proposed for sensitive detection of α-fetoprotein (AFP). Specifically, europium-doped TiO 2 (Eu-TiO 2 ) was used as the photoelectrochemical functional material and coated onto indium tin oxide (ITO) electrode. Doxorubicin (DOX) as an excellent fluorescent dye was encapsulated in the hydrophobically modified alginate (HMA). Then the dye-loaded HMA was modified onto the surface of Eu-TiO 2 to further sensitize the photocurrent response. The results showed that the photoelectrical signal was enhanced and stabilized due to the effect of sensitization of DOX on Eu-TiO 2 material. The constructed PEC sensor revealed a good linear response to AFP antigen ranging from 0.5 to 100 ng/mL with a detection limit of 0.41 pg/mL. The clinical patient’s serum test results obtained from the proposed PEC immunosensor were consistent with those obtained from the commercial electrochemilunescence assay. The proposed PEC sensing method could be a promising analytical tool for the detection of AFP in clinical analysis. Graphical abstract
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PubMed
高影响因子
Molecular Catalysis
·
2023
·
IF 4.6
Haoquan Guo,Xinyu Lu,Yue Yang,Jinhe Wei,Lizhi Wu,Li Tan,Yu Tang,Xiaoli Gu
Alkyl phenol is an essential chemical intermediate that is in high demand in the chemical industry. The synthesis of alkyl phenols from lignin-derived molecules is one of the most promising routes for utilizing biomass resources. Herein, we report the catalytic hydrodeoxygenation (HDO) of dihydroeugenol (DHE) to alkyl phenols over a highly dispersed Pd/α-MoC catalyst with a substrate conversion of 98% and a selectivity of 96% to alkyl phenols. The Pd/α-MoC catalyst prepared by co-precipitation and temperature-programmed carbonization exhibits exceptional HDO activity under mild conditions with a low H 2 pressure (1–10 bars). The characterizations of the catalyst suggest that Pd are highly dispersed on the α-MoC matrix. The reaction mechanism was investigated using the substrate scope experiments. Under ambient pressure, the abundant oxygen vacancies and acidity sites on Pd/α-MoC enable the selective hydrodeoxygenation of lignin monomers.
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高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2023
·
IF 4.2
Xuejuan Wei,Xiaopeng Chen,Linlin Wang,Xiaojie Wei,Yang Yang,Jiaqi Liang,Jiezhen Liang
Isothermal vapor–liquid equilibrium data of the binary system (−)-α-pinene + (−)-β-pinene and the quaternary system (−)-α-pinene + (−)-β-pinene + water + phenoxyacetic acid were measured at 313.2, 323.2, and 333.2 K using headspace gas chromatography. The experimental data showed that the addition of phenoxyacetic acid and water promoted the separation of (−)-α-pinene and (−)-β-pinene. The experimental data were correlated using the UNIQUAC and NRTL models. The two models showed good correlation for the binary system, whereas the UNIQUAC model gave more accuracy for the quaternary system. Moreover, the COSMO-RS model can be an efficacious method for predicting VLE data of the determined binary and quaternary systems. In addition, the optimal spatial configuration and binding energy between the molecules were obtained by DFT, and the effects on (−)-α-pinene and (−)-β-pinene with the addition of phenoxyacetic acid and water were discussed on the molecular scale.
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高影响因子
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