BIOSENSORS & BIOELECTRONICS
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2018
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IF 8.173
Hongxiao Yang,Jiagang Hou,Zhaohui Wang,Tingting Zhang,Caixia Xu
The accurate detection of the superoxide anion (O 2 •− ) has vital academic and medical diagnostic significance due to its important dual roles in biological functioning. In this work, hollow porous PtAg nanospheres (PtAg HPNSs) were fabricated by a facile hydrothermal method followed by a dealloying procedure. The as-made PtAg nanospheres possessed hollow interiors and porous shells composed of interconnected ligaments and pores with the typical size around 4 nm. Benefitting from the unique hollow nanoporous architecture and the specific alloying effect, the PtAg HPNSs showed high electrocatalytic activity towards superoxide anions. The constructed biosensor based on PtAg HPNSs presented a fast and ultrasensitive response in a wide range of 0.8–1080 nM with much higher sensitivity of 4.5 × 10 −2 μA cm −2 nM −1 and low detection limit of 0.2 nM (S/N = 3). Moreover, the novel biosensors can achieve electrochemical detection for O 2 •− released from living cells, exhibiting outstanding real time detection capability in cell environment. The facile controllable fabrication and unique sensing performance for PtAg HPNSs offers potential practical applications in developing highly sensitive and stable biosensor towards superoxide anion.
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Journal of Environmental Chemical Engineering
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2018
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IF 0
Baowei Wang,Shumei Yao,Yeping Peng,Yan Xu
Non-thermal plasma (NTP) combined with catalysts has been regarded as a promising approach for the removal of VOCs. In the present work, a series of TiO 2 -BaTiO 3 catalysts were prepared by simple mechanical mixing. The performance of the catalysts on degradation of high concentration of toluene was investigated in a dielectric barrier discharge (DBD) plasma system . The effects of input power, mass ratio of Ti/Ba, gas flow rate and the initial concentration of toluene on the removal of toluene and the selectivity of CO 2 as well as the energy yield have been investigated. The toluene removal efficiency and CO 2 selectivity increased obviously in the plasma-catalytic system compared with the single NTP system. The removal efficiency of toluene with different catalysts abided by the following rules: Ti1Ba1 > Ti2Ba1 > Ti1Ba2 > BaTiO 3 > TiO 2 . The reason for the best performance of Ti1Ba1 is that TiO 2 offered the providential number of electron-hole pairs while BaTiO 3 supplied the fitting number of high energy electrons . Additionally, the synergistic effects between TiO 2 and BaTiO 3 also reached its maximum in this case. The concentration of O 3 in the exhaust gas was also detected and it reached the lowest point when Ti1Ba1 catalyst was packed in the discharge chamber.
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CARBOHYDRATE POLYMERS
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2018
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IF 5.158
Zhanying Li,Lin Shao,Wenbin Hu,Tingting Zheng,Lingbin Lu,Yang Cao,Yongjun Chen
Absorption is one of the most important methods for oil spill cleanup. An ideal absorbent is expected to possess advantages of low cost, green, high absorption capacity and excellent reusability. In this paper, a new kind of cellulose aerogel was successfully fabricated via cellulose oxidation, crosslinking, freeze drying and cold plasma modification. The obtained aerogel (water contact angle up to 152.8°) exhibited outstanding oil/water selectivity and high absorption capacity (13.77–28.20 g/g) for various oils and organic solvents. What's more, this kind of aerogel could be reused by simple compression. The absorption-desorption process could be repeated for at least 50 cycles. Through the kinetic analysis, it was found that the pseudo-second order model was more appropriate for the aerogel’s oil absorption process. Owing to its low cost, hydrophobicity, high absorption capacity and excellent reusability, this kind of aerogel is expected to be used in oils and organic solvents spill cleanup and oil/water separation field.
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MATERIALS & DESIGN
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2018
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IF 4.525
Sen-Qiang Wu,Jing-Wen Wang,Jing Shao,Lei Wei,Ren-Kui Ge,Hua Ren
High dielectric constant (high- k ) polymeric materials suitable for electromechanical transducers should meet the requirements of low dielectric loss. This work introduced a ternary nanocomposite with acrylate elastomer (AE) as matrix, and chemically reduced graphene oxides (G) and poly(ionic liquid)s (PILs) as co-filler, of which AE was synthesized by solution polymerization . A unique hybrid (H) was fabricated by the ionic liquid monomers polymerized on the surface of graphene. Afterwards, hybrid of different filler contents was added into AE to prepare nanocomposites with solution casting method. The favorable π-π interaction between PILs and graphene made the co-filler a better dispersion in the matrix, which contributed to the enhanced dielectric property of the resultant nanocomposites. Dielectric constant of H/AE nanocomposite at 10 2 Hz was as high as 680 and the dielectric loss was only 0.34 when the filler content (1.69 vol%) approached to the percolation threshold ( f c ), which was attributed to PILs anchored on the surface of graphene acting as spacers and PILs cut the leakage currents induced by the direct connection of graphene. Moreover, the composite was still flexible that could engender larger strain in area.
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Journal of Chemistry
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2018
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IF 1.726
Dong Wang,Yujun Zhu
The bimetal catalyst Pt-Cu/SiO2 was prepared by the impregnation method. Its catalytic performance was investigated by the selective hydrogenation of cinnamaldehyde. Pt-Cu/SiO2 exhibited much higher selectivity (64.1%) to cinnamyl alcohol than Pt/SiO2 (3.7%), while they showed similar conversion of cinnamaldehyde. This enhancement was attributed to the increase in the amount of the Pt0 species on the Pt-Cu/SiO2 surface, which is derived from the interaction between Pt and Cu revealed by XRD and XPS.
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SENSORS AND ACTUATORS B-CHEMICAL
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2018
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IF 5.667
Linlin Hu,Xing Wei,Jie Meng,Xiaoyan Wang,Xuwei Chen,Jianhua Wang
The development of fluorescent probes for detection of glutathione (GSH) has attracted extensive attentions due to its close association with cellular functions and diseases. Herein, a fluorescence enhancement sensing system based on acetaldehyde-modified-cystine (AMC) is reported for the detection of thiols, providing detection limits of 36 and 52 μmol L −1 for GSH and cysteine (Cys) respectively. Importantly, the fluorescence response of AMC is highly selective toward thiols with respect to the coexisting species in real biological matrixes. Considering the fact that GSH levels in cancer cells is significantly higher than those of Cys and other reducing species, the fluorescence enhancing response of AMC in cancer cells is dominated by GSH. Therefore, this provides the possibility for selective intracellular GSH imaging in living cancer cells, i.e., HeLa cells in the present study.
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Nanoscale Research Letters
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2018
·Vol. 13
·期 1
·1-8
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IF 3.125
Yang Guo-hai,Bao Dan-dan,Zhang Da-qing,Wang Cheng,Qu Lu-lu,Li Hai-tao
Recent industrial developments and increased energy demand have resulted in significantly increased levels of environmental pollutants, which have become a serious global problem. Herein, we propose a novel all-carbon nanofiltration (NF) membrane that consists of multi-walled carbon nanotubes (MWCNTs) interposed between graphene oxide (GO) nanosheets to form a three-dimensional (3D) structure. The as-prepared membrane has abundant two-dimensional (2D) nanochannels that can physically sieve antibiotic molecules through electrostatic interaction. As a result, the prepared membrane, with a thickness of 4.26 μm, shows both a high adsorption of 99.23% for tetracycline hydrochloride (TCH) and a high water permeation of 16.12 L m − 2 h − 1 bar − 1 . In addition, the cationic dye methylene blue (MB) was also removed to an extent of 83.88%, indicating broad applications of the prepared membrane.
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RSC Advances
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2018
·Vol. 8
·期 3
·1361-1370
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IF 2.936
Song Li,Wenzhi Li,Qi Zhang,Riyang Shu,Huizhen Wang,Haosheng Xin,Longlong Ma
The lignin-first biorefinery method appears to be an attractive approach to produce phenolic chemicals. Herein, corn stover was employed for the production of phenolic monomers using an unsupported non-noble MoS2 catalyst. The yield of phenolic monomers was enhanced from 6.65% to 18.47% with MoS2 at 250 °C and about 75% lignin was degraded with more than 90% glucan reserved in the solid residues. The Fourier-Transform Infrared (FT-IR) and heteronuclear single quantum coherence-nuclear magnetic resonance (1H–13C HSQC-NMR) characterization suggested that the cleavage of the β-O-4, γ-ester and benzyl ether linkages were enhanced, promoting the delignification and the depolymerization of lignin. The catalyst performance was relatively effective with 14.30% phenolic monomer yield after the fifth run. The effects of the reaction temperature, the initial hydrogen pressure, the dosage of catalyst, and the reaction time were investigated. The model reactions were also proposed for the potential mechanism study. This work provides some basic information for the improvement of the graminaceous plant lignin-first process with a non-noble metal catalyst.
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CHEMICAL ENGINEERING SCIENCE
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2018
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IF 3.306
Qing Li,Xiaofang Zhu,Ying Zhang,Zhigang Zak Fang,Shili Zheng,Pei Sun,Yang Xia,Ping Li,Yang Zhang,Xing Zou
Hydrogen assisted magnesiothermic reduction (HAMR) of TiO 2 is a promising new process developed recently to produce Ti metal with low cost and less energy consumption. This work focuses on the understanding and optimization of the reduction process to control the quality of the reduced product. TiO 2 precursor particles with different relative densities were prepared, and the effects of the relative densities on reduction by Mg in H 2 were studied. The changes of oxygen contents vs. reduction time at various temperatures were investigated. The phase transformations during the reduction were analyzed both theoretically and experimentally. The relationship between the morphology of the reduced products and the relative densities of the TiO 2 precursors was analyzed by SEM characterization and the likely reason for the morphology evolution was discussed.
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BIOMEDICINE & PHARMACOTHERAPY
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2018
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IF 3.457
Yuhui Wang,Jinyang Shen,Xiaolin Yang,Ye Jin,Zhonglin Yang,Rufeng Wang,Fuming Zhang,Robert J. Linhardt
Background Glucocorticoid hormones are implicated in the pathogenesis of Alzheimer’s disease (AD) and other diseases including diabetes, hyperlipidemia , and osteoporosis . Akebia saponin D (ASD) possesses numerous pharmacological activities , including as an anti-AD, anti-hyperlipidemia, anti-diabetes, and anti-osteoporosis agent. The anti-AD effect of ASD is possibly through its regulation of glucocorticoid levels. Purpose The present study was undertaken to investigate the neuroprotective effects of ASD on Aβ 25-35 -induced cognitive deficits and to elucidate its underlying mechanism of action. Methods The AD rat model was established by an intracerebroventricular injection of Aβ 25-35 into the lateral ventricles. Spatial learning and anxiety state were assessed by Morris water maze task and elevated plus-maze assay, respectively. The degree of hypertrophy of adrenal gland was analyzed using the viscera coefficient. Corticosterone and ACTH concentrations in the plasm were measured using biochemical assay kits. The activity of 11β-hydroxysteroid dehydrogenase type-1 (11β-HSD1) in liver and groin fat pad was assessed by measuring cortisol production. Results Compared with the control group, AD rats displayed significant spatial learning and reference memory impairments, serious anxiety disorders, obvious hypertrophy of adrenal gland, elevated corticosterone and ACTH levels in the plasma, and increased 11β-HSD1 activity in liver and groin fat pad. ASD could significantly ameliorate the memory deficits and anxiety symptoms, markedly reduce the viscera coefficient of adrenal gland, observably decrease corticosterone and ACTH concentrations, and showed no effect on the activity of 11β-HSD1. Conclusions These results indicate that ASD might exert a significant neuroprotective effect on cognitive impairment, driven in part by reducing systemic corticosterone level by down-regulation of the hypothalamic-pituitary-adrenal (HPA) axis.
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ACS Applied Materials & Interfaces
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2018
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IF 8.097
Qiuwen Wu,Gen Wei,Zhuobin Xu,Jing Han,Juqun Xi,Lei Fan,Lizeng Gao
Infections caused by bacteria are a growing global challenge for public health as bacteria develop resistance, which will cause the failure of anti-infective treatment eventually. An effective alternative strategy to traditional antibacterial therapy is utilizing reactive oxygen species (ROS) to kill bacteria. Here, we report a simple route to prepare PEGylated nitrogen-doped carbon capsules (PEG-N-CCs) as an antibacterial agent. The PEG-N-CCs can translate near-infrared light (NIR) into heat and produce a high concentration of ROS triggered by NIR irradiation. Both heating and ROS are critical to destroy the outer membranes and rupture cell bodies, causing DNA fragmentation and glutathione oxidation both in Gram-negative Escherichia coli, Gram-positive Staphylococcus aureus, and their multidrug-resistant strains. Moreover, PEG-N-CCs plus NIR irradiation can efficiently scavenge the existing biofilms and prevent the formation of new biofilms, killing planktonic bacteria as well as those within the biofilm. Our studies prove that the PEG-N-CCs plus NIR irradiation can provide a simple and effective platform for combating bacteria, employing carbon nanomaterials as an antibacterial alternative for treatment of infectious diseases.
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Nanoscale
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2019
·Vol. 11
·期 18
·8898-8905
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IF 6.97
Luhong Fu,Xin Hu,Yunbo Li,Gongzhen Cheng,Wei Luo
Developing highly efficient and durable electrocatalysts for overall water splitting over a wide pH range is of great interest for practical applications, but still remains a challenge. Specifically, to the best of our knowledge, a 3-in-1 electrocatalyst that can efficiently catalyze overall water splitting in acidic, alkaline, and neutral electrolytes has not been reported so far. Herein, we report the colloidal synthesis of well-dispersed IrW nanobranches with branch architectures and describe how the morphology varies with the amount of W doping. As expected, they exhibit outstanding catalytic performance and durability for the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) at all pH values, which are much higher than those of Ir nanoparticles (NPs), and most reported state-of-the-art electrocatalysts. More importantly, when further used as both an anode and cathode for overall water splitting in 0.1 M HClO4, 0.1 M KOH, and 1.0 M PBS (phosphate buffer solution), cell voltages of 1.58, 1.60, and 1.73 V, respectively, were achieved at a current density of 10 mA cm−2. The present work opens up a new avenue for designing electrocatalysts for pH-universal overall water splitting, especially for application in highly corrosive acidic media and neutral media with limited ionic concentrations.
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