CHEMICAL ENGINEERING JOURNAL
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2017
·
IF 6.216
Nan Zhang,Xiaoling Hu,Ping Guan,Chunbao Du,Ji Li,Liwei Qian,Xiaoyan Zhang,Shichao Ding,Bangpeng Li
Design and preparation of functional materials for selective recognition of biomacromolecules such as proteins, DNA, viruses, and bacteria have always been extremely challenging due to their structure sensitivity. Regrettably, the structure stability of biomacromolecules in molecularly imprinted technology was rarely addressed. This paper presents an effective procedure for the facile preparation of bovine serum albumin (BSA) interfacial molecularly imprinted microspheres (IMIMs), using an imidazole-based amphiphilic ionic liquid (IL), which played a dual role of a stabilizer and emulsifier, via miniemulsion polymerization at 25 °C. In order to prove the stabilizing effect of IL on BSA, a conventional emulsifier sodium dodecyl sulfate (SDS), was also used as the emulsifier for comparison. Different characterization methods were employed to investigate the stability of BSA structure and track the experimental process. The results reveal that the destruction of structure of BSA by amphiphilic IL, 1-dodecyl-3-methylimidazolium chloride ([DMM]Cl), was much lower than that by SDS. Moreover, good selectivity of IMIMs-[DMM]Cl towards BSA was certified in the batch-wise and selectivity rebinding tests, in which an imprinting factor of 3.32 was obtained. This was superior to IMIMs-SDS and demonstrated to be a promising platform for recognition of protein with good specificity.
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高影响因子
Food Analytical Methods
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2016
·Vol. 9
·期 9
·2491-2500
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IF 2.167
Fan Yunchang,Hu Guitao,Zhang Tianao,Dong Xing,Zhong Yingying,Li Xiaojing,Miao Juan,Hua Shaofeng
A sensitive electrochemical glucose biosensor based on chitosan (CS)/glucose oxidase (GOx)/catalase (CAT)/CS + carboxylic multi-walled carbon nanotubes (MWCNTs-COOH) + ionic liquid (IL) film modified glassy carbon electrode has been developed and its characteristics were investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Hydrogen peroxide (H 2 O 2 ) generated during the enzymatic reaction of GOx with glucose could be decomposed by catalase, resulting in the higher sensitivity. The linear range and detection limit were found to be 0.5–100 and 0.2 μmol L −1 , respectively. The proposed biosensor was successfully applied for the determination of glucose in drink and food samples with the spiked recoveries in the range of 95.5 to 101.5 %.
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CATALYSIS TODAY
·
2016
·
IF 4.312
Yibo He,Qinghua Zhang,Xiaoli Zhan,Dang-guo Cheng,Fengqiu Chen
Friedel–Crafts alkylation of benzene with 1-dodecene, which is an important reaction of synthetic detergent, was studied via ionic liquid [bmim][TFSI]/AlCl 3 (1-butyl-3-methylimidazolium bis((trifluoromethyl)sulfonyl)imide/AlCl 3 ) immobilized on SBA-15 catalysts. XRD, BET, TEM, TG, ammonia TPD investigations were used to search insight into catalyst characteristic. The immobilized catalysts preserved ordered structure and presented high specific surface areas. The utilization of active sites was significantly improved by immobilization. Based on ammonia TPD, immobilized catalysts exhibited higher Lewis acidity than aluminum chloride grafted SBA-15. TG indicated that thermal stability of ionic liquid has been improved by immobilization. The influences of various reaction conditions including reaction time, benzene/1-dodecene ratio were studied. Immobilized ionic liquids have better performance of no matter 1-dodecene conversion or 2-linear alkyl benzene (2-LAB) selectivity, than bulk ionic liquid catalysts or aluminum chloride grafted mesoporous materials. 2-LAB selectivity can be increased from about 35% with bulk ionic liquid to more than 60% with immobilized catalysts. Under optimal condition, 2-LAB selectivity reached as high as 80%. The immobilized catalysts could be reused. And at 3th cycle of catalysts, 1-dodecene conversion could still reach more than 50%. The role of deactivation was proposed based on TEM, BET and TG investigations. By-products as oligomer , produced by oligomerization of olefin , blocked or covered the pores, led to deactivation of catalysts.
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JOURNAL OF MOLECULAR LIQUIDS
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2016
·
IF 2.74
Chenglong Shi,Yongzhong Jia,Jiang Xiao,Xingquan Wang,Ying Yao,Yan Jing
In this paper, a novel liquid-liquid extraction system was investigated for the selective separation of lithium isotopes using ionic liquid (IL) and dichloroethane as extraction solvent and dibenzo-14-crown-4 (DB14C4) as extractant. Results showed that the separation performance of DB14C4 has been improved after the ILs were involved in the extraction process. The maximum single stage separation factor α for 6 Li/ 7 Li obtained in the present study was 1.021. The light lithium isotope 6 Li and the heavy lithium isotope 7 Li were concentrated in organic phase and solution phase, respectively. The order of the single stage separation factor obtained in different lithium salts was LiI > LiBr > LiClO 4 > LiCl. From the temperature dependence data, the thermodynamic functions values of the lithium isotope exchange reaction were calculated.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2017
·
IF 2.843
Yongli Sun,Hanrong Bi,Haozhen Dou,Huawei Yang,Zhaohe Huang,Baoyu Wang,Rong Deng,Luhong Zhang
For the separation of an ethylene/ethane mixture, a novel copper(I)-based supported ionic liquid membrane (SILM) with high permeability has been fabricated. This SILM was prepared from a polyvinylidene fluoride microporous membrane impregnating the copper(I) based IL which formed by the cuprous chloride (CuCl) and 1-butyl-3-methylimidazolium chloride ([Bmim][Cl]). Scanning electron microscopy, attenuated total reflection Fourier transform infrared spectroscopy, and time of flight mass spectroscopy were used to characterize the SILM. Pure and mixed gas permeation experiments were carried out to investigate the influences of ILs composition, trans-membrane pressure, temperature, and time upon the separation performance. This SILM showed comparable C2H4 permselectivity but outstanding permeability with a long-term stability beyond the reported polymeric membrane upper bound. At the CuCl/[Bmim][Cl] ratio of 2, the C2H4 permeability and permselectivity reached 2653 barrer and 11.8, respectively. Furthermore, the facilitated transport effect was studied by 1H NMR and quantum mechanical calculations. The anionic species formed by sp hybridization of Cu+ possesses unfilled attachment sites to selectively complex with C2H4 and weaken the interionic hydrogen bond of [Bmim][Cl], thus lowering the system’s viscosity.
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TRIBOLOGY INTERNATIONAL
·
2017
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IF 2.903
Huimin Qi,Yuexia Guo,Ligang Zhang,Guitao Li,Ga Zhang,Tingmei Wang,Qihua Wang
In order to further enhance the tribological performance of a polyimide composite subjected to water lubrication rubbing with stainless steel, functionalized mesoporous SiO 2 nanoparticles were blended into water as a new lubrication additive. Novel poly (1-(4-vinylbenzyl)-3-methylimidazolium chloride) IL was synthesized and grafted onto mesoporous SiO 2 (SiO 2 -IL) via an atom transfer radical polymerization route. It was demonstrated that SiO 2 -IL as water additives significantly reduced the friction coefficient and wear of the polyimide composite. Comprehensive analyses of the worn surfaces indicated that the grafted IL layer facilitated the formation of a protective tribofilm, separating the direct rubbing and alleviating tribo-oxidation of the steel surface. This work proposed a new route for enhancing water lubricated polymer-metal rubbing pairs.
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BIOMACROMOLECULES
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2017
·
IF 5.246
Zhi-Yong Guo,Xin Hai,Yi-Ting Wang,Yang Shu,Xu-Wei Chen,Jian-Hua Wang
A novel zwitterionic polymer ionic liquid functionalized magnetic nanospheres, shortly as Fe3O4@PCL-PILs, is synthesized by grafting ionic liquid VimCOOHBr onto polymer ε-caprolactone (PCL) modified magnetic nanospheres via esterification and surface-initiated free radical polymerization. This established synthesis strategy offers the obtained magnetic nanospheres with well-defined core–corona structure, compact grafting layer, favorable zwitterionic and negative-charged surface, and high magnetic susceptibility. The as-prepared Fe3O4@PCL-PILs nanospheres exhibit typical “zwitterionic hydrophilic interaction liquid chromatography (ZIC-HILIC)” behaviors toward protein binding, and selectively adsorption of glycoprotein is achieved. The adsorption capacity of the magnetic nanospheres toward Immunoglobulin G is high up to 1136.4 mg g–1, and the captured Immunoglobulin G could be efficiently recovered by using 0.5% NH3 H2O (v/v) as stripping reagent, providing a recovery of 80.5%. Fe3O4@PCL-PILs nanospheres are then employed as sorbent for the selective isolation of Immunoglobulin G from human whole blood, obtaining high-purity Immunoglobulin G as demonstrated by polyacrylamide gel electrophoresis assays.
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PubMed
高影响因子
Polymers
·
2017
·Vol. 9
·期 10
·526
·
IF 3.364
Hui Zhang,Yaoguang Xu,Yuqi Li,Zexiang Lu,Shilin Cao,Mizi Fan,Liulian Huang,Lihui Chen
A facile cellulose solvent 1,3-diallyl-2-ethylimidazolium acetate ([AAeim][OAc]) with high electrical conductivity has been designed and synthesized for the first time, via a quaternization reaction and ion exchange method. The dissolution characteristics of cellulose in this solvent were studied in detail. Meanwhile, the co-solvent system was designed by adding an aprotic polar solvent dimethyl sulfoxide (DMSO) in [AAeim][OAc]. The effects of temperature and the mass ratio of DMSO to [AAeim][OAc] on the solubility of cellulose were studied. Furthermore, the effects of regeneration on the molecular structure and thermal stability of cellulose were determined by Fourier transform infrared spectroscopy (FT-IR), thermal gravity analysis (TGA) and X-ray diffraction (XRD). The findings revealed that the synthesized ionic liquid (IL) has a relatively low viscosity, high conductivity and a good dissolving capacity for bamboo dissolving pulp cellulose (Degree of Polymerization: DP = 650). The macromolecular chain of the cellulose is less damaged during the dissolution and regeneration process. Due to the increased number of “free” anions [OAc]−and cations [AAeim]+, the addition of DMSO can significantly increase the solubility of the cellulose up to 12 wt % at the mass ratio of 3:1, indicating that the synthesized IL has a potential application in the electrospinning field.Keywords:1,3-diallyl-2-ethylimidazolium acetate;ionic liquid;co-solvent system;solubility of cellulose;electrospinning
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高影响因子
RSC Advances
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2016
·Vol. 6
·期 101
·99361-99366
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IF 3.289
Lan Lei,Lin Feng,Binglei Song,Zhaolan Zhai,Shibin Shang,Zhanqian Song
Modification of the molecular structures of surfactants is a feasible way to construct ionic liquid crystals (ILCs) with novel properties. Five quaternary ammonium gemini surfactants with different spacers, whose head groups were substituted by four hydroxyethyl groups, abbreviated as 12(2OH)-s-12-(2OH) (s = 3, 4, 5, 6, 8), were prepared. The mesomorphic behaviors of these gemini surfactants were investigated by polarized optical microscopy (POM), differential scanning calorimetry (DSC), X-ray diffraction (XRD) and temperature-dependent FT-IR spectroscopy. These surfactants form smectic A (SmA) phases, the region of which is dependent on the spacer length. The presence of suitable spacer length and multiple hydroxyl groups is helpful in stabilizing the mesophases. Noticeably, because of synergistic effect of the spacer and the hydroxyl groups, the phase enthalpy change of SmA to crystal transitions can be slowly released below the phase transition temperature. This interesting discovery, which has never been reported in ILC systems formed by small molecular weight surfactants, could pave the way for special applications of ILCs in the area of sustained-release materials of heat and could widen the application of ionic liquid crystals.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2012
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IF 2.237
Fang-fang Tong,Hong Xu,Jian Yu,Li-xiong Wen,Jun Zhang,Jia-song He
A series of poly(methyl methacrylate) (PMMA)/1-dodecyl-3-methylimidazolium hexafluorophosphate ionic liquid ([C12MIM][PF6]) blends were prepared by melt blending. The compatibility of blends was verified by scanning electron microscopy and differential scanning calorimetry. The introduction of [C12MIM][PF6] decreased the glass transition temperature of the blends due to its plasticization effect and increased the diffusivity of CO2 without significantly affecting the CO2 solubility. These blends were foamed with supercritical CO2 as the blowing agent via a pressure-quenching process. The foaming conditions are divided into three regions according to the main morphological difference of foams. At relatively low temperatures and pressures, neat PMMA could not be foamed, while the addition of [C12MIM][PF6] facilitated the formation of cells. By increasing temperature or pressure, neat PMMA foams were obtained with wide cell size distribution, while the blend foams were formed with narrowed cell size distribution and increased cell size. At high temperatures and pressures, neat PMMA was foamed with narrow cell size distribution and high cell density, while the major effect of [C12MIM][PF6] was to increase the cell size. These results indicated that the plasticization effect and the low surface energy of [C12MIM][PF6] accounted for the differences on the cell morphology between neat PMMA and the blend foams.
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Analytical Methods
·
2014
·Vol. 6
·期 12
·4067-4076
·
IF 1.938
Jing Chen,Yuzhi Wang,Qun Zeng,Xueqin Ding,Yanhua Huang
A series of hydroxyl ammonium ionic liquids (ILs) have been designed and synthesized. An ionic liquid aqueous two-phase system based on N,N-dimethylethanolamine propionate ([DMEA][Pr]) ionic liquid was studied for the extraction of proteins. Based on the single-factor experiment, an initial serial investigative test was used to identify the optimal conditions. Five factors and four levels of orthogonal experiments were used to verify the optimum extraction conditions. The results show that under the optimum conditions, the extraction efficiency could reach up to 99.50%. The RSD of extraction efficiencies in precision experiment, repeatability experiment and stability experiment were 0.3% (n = 5), 1.1% (n = 5) and 1.5% (n = 5), respectively. The conformation of the proteins was not affected after extraction into the IL-rich phase in terms of the determination by UV-vis and FT-IR spectra. According to the determination of conductivity, dynamic light scattering, and transmission electron microscope images, the microstructure of the IL-rich phase and the possible mechanism for the extraction are investigated. Hydrogen bonding interaction, salt out effect and the aggregation phenomenon played important roles in the extraction. The circular dichroism spectral experiment analysis indicated that the secondary structures of the protein were unchanged after extract. Based on these findings, it is suggested that the method of hydroxyl ammonium-based ILs-ATPs have the potential to offer new possibility in the extraction of bio-analytes.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2013
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IF 1.977
Zhi-Yuan Yan,Li-Ping Jia,Bing Yan
Two typical kinds of rare earth fluoride nanocrystals codoped with rare earth ions (Eu 3+ and Tm 3+ /Er 3+ ,Yb 3+ ) are synthesized and dispersed in ionic liquid compound (1-chlorohexane-3-methylimidazolium chloride, abbreviated as [C 6 mim][Cl]). Assisted by agarose, the luminescent hydrogels are prepared homogeneously. The down/up-conversion luminescence of these hydrogels can be realized for the dispersed rare earth fluoride nanocrystals. The results provide a strategy to prepare luminescent (especially up-conversion luminescent) hydrogels with ionic liquid to disperse rare earth fluoride nanocrystals.
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危险品化学品经营许可证（带存储）