MATERIALS & DESIGN
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2018
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IF 4.525
Daoyong Mao,Qing Li,Daikun Li,Ya Tan,Qijun Che
Natural-synthetic hybrid scaffold has attracted great interest due to its synergistic effect on load-bearing bone reconstruction. Herein, sodium alginate (SA)/gelatin (Gel) composite were combined with poly(ε-caprolactone)/58S bioactive glass (PCL/BG) composite to construct natural-synthetic hybrid scaffold by a modified melt molding method. Our results showed that the SA/Gel microspheres used as porogen remained inside the scaffold, which had potential benefits for cell adhesion. The PCL/BG composite acted as the struts. The incorporation of BG resulted in a significant increase in the mechanical properties of the scaffold. Specially, HS-3 scaffold showed a compressive strength of 1.44 ± 0.02 MPa falling within the range of values reported for the cancellous bone. In addition, the presence of BG improved wettability and biodegradability of the scaffold, thus potentially enhancing osteointegration. In conclusion, the PCL/BG–SA/Gel hybrid scaffold with improved mechanical properties and potential cytocompatibility are promising biomaterials for bone repair.
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高影响因子
Journal of the Taiwan Institute of Chemical Engineers
·
2019
·
IF 3.834
Zhixing Xiao,Lijuan Zhang,Long Wu,Dan Chen
In this study, a novel adsorbent was synthesized through the entrapment of KMnO 4 modified biochar (MB) in poly(vinyl alcohol)/sodium alginate hydrogel bead (PSMB) and then tested to determine its capacity for removal of Cu(II) from aqueous solutions. The maximum Cu(II) adsorption capacity estimated with Langmuir isotherm modeling was 87.07 mg/g of PSMB, which was higher than that of previously reported adsorbents. PSMB had a good selectivity towards Cu(II) as well as high anti-interference ability. The main species for Cu(II) adsorption likely were the inner-sphere Cu-O complexes, as indicated by the results of spectral analyses. The PSMB was easily collected and exhibited a minimal loss of adsorption capacity after 10 adsorption/regeneration cycles. The effective removal of Cu(II) from environmental water samples with relative low treatment cost indicated a possibility for practical application.
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Surfaces and Interfaces
·
2025
·
IF 6.3
Senyang Wang,Yingdi Zhou,Bo Huang,Jingyi Qi,Mengting Hua,Xiaoshi Jin,Ling Li
The practical progression of quantum-dot sensitized solar cells (QDSSCs) due to the poor stability, which directly related to the leakage and volatileness of liquid electrolyte. Herein, the sodium alginate (SA) polysulfide gel electrolyte prepared by grinding method was first applied in the quasi-solid state QDSSCs. It has a pore structure which can elevate the rapid diffusion of ions. And the cross-linked interface with photoanode is smooth and non-adherent. The SA polysulfide gel electrolyte was used in Zn-Cu-In-Se (ZCISe) QDSSCs for standard experiments. The QDSSCs are able to materialize the photoelectric conversion efficiency (PCE) of 8.85 % (V oc is 0.63 V, J sc is 26.16 mA·cm −2 , FF is 51.80), which is 6 % higher than the liquid polysulfide QDSSCs (8.34 %). Above all, the stability is 3.2 times higher than that of liquid polysulfide electrolyte. The research fulfilled the goal of both efficiency and stability, also environmentally friendly.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2024
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IF 5.7
Jianing Zhang,Junjun Zhang,Xinai Zhang,Xiaowei Huang,Jiyong Shi,Remah Sobhy,Ibrahim Khalifa,Xiaobo Zou
In this study, we devised a photothermally stable phytochemical dye by leveraging alizarin in conjunction with the metal–organic framework ZIF-8 (AL@ZIF-8). The approach involved grafting alizarin into the microporous structure of ZIF-8 through physical adsorption and hydrogen-bonding interactions. AL@ZIF-8 significantly enhanced the photostability and thermostability of alizarin. The nanoparticles demonstrate substantial color changes in various pH environments, showcasing their potential for meat freshness monitoring. Furthermore, we introduced an intelligent film utilizing poly(vinyl alcohol)-sodium alginate-AL@ZIF-8 (PA-SA-ZA) for detecting beef freshness. The sensor exhibited a superior water contact angle (52.34°) compared to the alizarin indicator. The color stability of the film was significantly enhanced under visible and UV light (ΔE < 5). During beef storage, the film displayed significant color fluctuations correlating with TVB-N (R2=0.9067), providing precise early warning signals for assessing beef freshness.
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PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Miaomiao Chen,Meng Zhou,Yunyun Wang,Caihong Mao,Shujie Pang,Ting Meng,Xudong Yang
To address the challenges associated with the storage and application of traditional carbon dot (CDs) solutions, this study introduces a cyan fluorescent carbon dot-based hydrogel (CDs-SCH). The hydrogel was synthesized by integrating cyan fluorescent CDs, derived from penicillamine and m -phenylenediamine, with carboxymethylcellulose (CMC) and sodium alginate (SA), which was then mixed with acrylamide (AM). The resulting CDs-SCH hydrogel was extensively characterized, focusing on its morphology, chemical structure, and fluorescence behavior. The fluorescence intensity of the hydrogel was enhanced by 3.23 times compared to the original CDs. The fluorescence response of the CDs-SCH hydrogel to pH variations was examined, demonstrating its capability to visually monitor the freshness of aquatic products such as fish and shrimp. Furthermore, Al 3+ and Ag + ions were found to significantly modulate the fluorescence, with Al 3+ enhancing and Ag + quenching the fluorescence, displaying reliable detection limits and linearity. The hydrogel's ability to detect glutathione (GSH) via Ag + reduction to Ag was also explored. Additionally, the hydrogel exhibited stable Al 3+ adsorption, with the process following pseudo-second-order kinetics and the Langmuir adsorption model. As a versatile and responsive material, the CDs-SCH hydrogel holds potential for applications in intelligent food packaging and environmental ion detection.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Jiayu Ouyang,Wenzhuo Lv,Canhui Wang,Xin Guo,Huiying Lv,Yiqiang Wu
Achieving a balance between catalytic efficiency and structural durability remains a key challenge in heterogeneous photo-Fenton-like systems. Herein, we report a robust sodium alginate hydrogel (ACCN) with hard–soft dual interpenetrating networks, constructed by incorporating Cu@MoS 2 nanosheets and carbon dots-modified cellulose nanofibrils (CNF@CDs). This structural design enables pan-regional photo-Fenton-like catalysis via structural optimization and directed electron transport, thereby ensuring sustained ciprofloxacin (CIP) degradation. Three key features synergistically enhance both catalytic performance and material integrity: (1) a dual interpenetrating network comprising Cu 2+ -crosslinked sodium alginate (SA, soft phase) and hydrogen-bonded CNF@CDs (rigid phase), which reinforces mechanical strength and prevents Cu@MoS 2 leaching; (2) the SA/CNF@CDs network exhibits an ultrahigh CIP adsorption capacity, which spatially concentrates pollutants and accelerates reaction kinetics; and (3) CNF@CDs facilitates electron transfer from Cu@MoS 2 to Cu 2+ crosslinking sites, promoting pan-regional Cu 2+ /Cu + redox cycling. This spatial–electronic integration endows ACCN with a CIP degradation rate constant of 0.0426 min −1 —7.5-fold higher than that of Cu@MoS 2 . Furthermore, ACCN demonstrates excellent durability and reusability, maintaining over 95 % catalytic activity after 10 cycles, with Mo leaching below 8 ppb. This work provides a sustainable strategy for integrating structural and electronic modulation to enable high-efficiency, durable antibiotic wastewater treatment.
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FOOD HYDROCOLLOIDS
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2024
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IF 11
Liyuan Ma,Weiyi Long,Yixiang Liu
Protein-based delivery systems tend to degrade too quickly in the gastrointestinal tract. Applying polysaccharide-based surface coatings on protein carriers is an effective strategy to prevent interference from gastric acid and proteases during the digestive process. This study prepared gastrointestinal pH-responsive bovine serum albumin (BSA)-myristic acid (MA) carriers using sodium alginate (SA)-based surface coating technology to improve the digestive properties and intestinal mucus penetration of limonin (LM). The results showed that ultrasonication caused uniform hydrophilic BSA and MA particle formation in optimal conditions. Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) observations confirmed that SA adhered to the BSA-MA particle surfaces via electrostatic interaction at pH 4, causing the controlled gastrointestinal release of the self-assembled BSA-MA complexes. The subsequent SA-BSA-MA complexes displayed an LM encapsulation yield (EY) of >84%. In vitro, simulated gastrointestinal digestion indicated that compared with free LM, the SA-BSA-MA particles significantly increased the intestinal LM retention rate, bioaccessibility, and micellization rate by 45.49%, 155.48%, and 102.14%, respectively. The results of the artificial intestinal mucus experiments demonstrated that the trans-intestinal mucus barrier capacity of SA-BSA-MA particle-loaded LM was significantly enhanced. Its apparent permeability coefficient (Papp) (6.53 × 10 −6 cm/s for free LM) and intestinal mucus permeability (17.56% for free LM) increased substantially to 14.22 × 10 −6 cm/s and 38.22%. This study presents a gastrointestinal pH-responsive delivery system that effectively improves the ability of hydrophobic nutrients to cross the intestinal mucus barrier.
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FOOD HYDROCOLLOIDS
·
2025
·
IF 12.4
Yujing Lu,Yicheng Guo,Jiarui Jin,Jiahao Xie,Xiufang Dong,Hang Qi
Polyphenols from Ascophyllum nodosum (PEAn) exhibit bioactivity but are prone to structural instability due to their polyhydroxy groups. To address this limitation, we developed pH-responsive hydrogel microspheres through enzymatic fibrillation modification of soybean protein isolate (SPI). Trypsin-induced fibrillation of SPI at neutral pH (7.0) produced β-sheet-rich nanofibrils (SNF), which were crosslinked with sodium alginate (SA) to form composite microspheres. The optimized microspheres achieved an encapsulation efficiency of 73.89 ± 1.07 %, along with enhanced water retention capacity, freeze-thaw stability, and significantly improved DPPH radical scavenging activity. The microspheres exhibited pH-dependent release behavior: less than 10 % of PEAn was released in pH 1.2 within 48 h, whereas a cumulative release of 88.4 % was observed in pH 7.4 via a swelling-driven mechanism. Release kinetics followed the Higuchi model in SGF and the Korsmeyer–Peppas model in SIF, indicating diffusion-controlled and erosion-controlled mechanisms, respectively. This strategy demonstrates a green, solvent-free approach to fabricate biopolymer-based delivery systems that protect unstable bioactives and enable controlled intestinal release, offering potential applications in functional foods and nutraceuticals.
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Frontiers in Nutrition
·
2022
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IF 6.59
Pei Juxin,Mei Jun,Yu Huijie,Qiu Weiqiang,Xie Jing
This research was done to investigate the synergistic interactions of the gum tragacanth (GT)–sodium alginate (SA) active coatings, incorporated with epigallocatechin gallate and lysozyme, on the quality of large yellow croaker (Larimichthys crocea) during superchilling storage at −3°C. Results showed that the GT-SA active coatings, containing epigallocatechin gallate [EGCG (E), 0.32% w/v], and lysozyme [LYS (L), 0.32% w/v] have reduced the total viable count, psychrophilic bacteria, and Pseudomonas spp. by about 1.55 log CFU/g, 0.49 log CFU/g, and 1.64 log CFU/g compared to the control at day 35. The GT-SA active coatings containing EGCG and LYS were effective in lowering the formations of off-odor compounds such as total volatile basic nitrogen (TVB-N), malondialdehyde (MDA), and off-favor amino acid (histidine). The solid phase microextraction gas chromatography-mass spectrometer (SPME-GC/MS) was applied to characterize and to quantify the volatile compounds of large yellow croaker samples during superchilling storage, while the relative content of the fishy flavor compounds (including 1-octen-3-ol and acetoin) was significantly reduced in the active coatings treated samples. Furthermore, the GT-SA active coatings containing EGCG and LYS treatments was found to be more effective in retarding the migration of water based on magnetic resonance imaging (MRI) results and in maintaining the organoleptic quality of large yellow croaker in superchilling storage at −3°C according to the sensory evaluation results. The results showed that the GT-SA active coating containing EGCG and LYS was effective to be used as a fish preservative to improve the quality and to prolong the shelf life of large yellow croaker in a superchilling storage for at least 7 days.
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PubMed
高影响因子
Food & Function
·
2022
·Vol. 13
·期 20
·10710-10723
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IF 6.317
Wei Niu,Yuxuan Chen,Ligui Wang,Jia Li,Zhao Cui,Jiajie Lv,Fuyan Yang,Jiege Huo,Zhenhai Zhang,Jianming Ju
Chlorogenic acid (CA) and sodium alginate (SA) each have good therapeutic effects on ulcerative colitis (UC) owing to their antioxidant and anti-inflammatory activity. This study aimed to investigate the effects of CA alone and in combination with SA on inflammatory cells and UC mice. In the Lipopolysaccharide (LPS)-induced RAW 264.7 inflammatory cell model, Nitric oxide (NO) and interleukin-6 (IL-6) levels were significantly lower after treatment with CA plus SA than with CA alone. In the DSS-induced UC mouse model, compared with CA alone, CA plus SA showed a better ability to alleviate weight loss, reduce the disease activity index (DAI), improve the colonic mucosa, reduce the expression of inflammatory factors in the serum and myeloperoxidase (MPO) in colonic tissue, increase superoxide dismutase (SOD) levels, protect the intestinal mucosa and regulate the abundance of Actinobacteriota, Lactobacillus, Bifidobacterium, Bacteroides, Subdoligranulum and Streptococcus. Thus, CA plus SA can improve the therapeutic efficacy of CA in UC by regulating inflammatory factors, oxidative stress, and the intestinal flora and by protecting ulcerative wounds. These findings broaden our understanding of the role of the combination of SA and CA in enhancing the effects of CA on UC and provide strategies for prevention and treatment.
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高影响因子
CARBOHYDRATE POLYMERS
·
2025
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IF 12.5
Tianyun Lu,Xiaokun Han,He Wang,Guiting Liu
Natural polymers are considered powerful candidate for preparing a new generation of intelligent sensors, however, their application in fire environment is limited restricted by the low flame retardancy and thermal stability. Herein, we developed a novel flexible film (SSGP) entirely composed of bio-mass, namely natural silk nanofibers, sodium alginate and phytic acid, via solution casting and self-assembly strategy. It exhibited reliable tensile properties (11.01 MPa), high flame retardancy (LOI reached 38 %), and thermal stability. Specifically, SSGP not only showed sensitive and reversible response at different temperatures (50-125 °C) with a GF of 10.8, but also triggered warning within 2.2 s of being exposed to a flame without being incinerated. Moreover, SSGP responded to humidity changes in the environment (22-94 % RH) and could be used for respiratory monitoring, with a response/recovery time of only 0.76 s/1.01 s. Additionally, SSGP based on natural polymers retain degradability (39.8 % within 30 days). Thus, SSGP had the potential to be integrated as a core component into sensor for real-time monitoring of ambient temperature and respiration of personnel in steelworks, fire rescue, battlefield and other flame environment. This study may provide new insights into the application of natural polymers in the flexible multifunctional sensor.
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高影响因子
COMPOSITES COMMUNICATIONS
·
2025
·
IF 7.7
Shitong Li,Hanyu Chu,Shizhuo Li,Xinyu Wang,Tong Qiu,Han Yan
Electronic skin (e-skin) can monitor various physiological indicators of the human body in real-time, which has a wide application prospect in personalized medicine and health care. Nevertheless, the development of e-skin is hindered by the skin discomfort caused by the dense matrix of traditional e-skin and the electronic waste (e-waste) generated by non-degradable components. To solve these problems, this study proposes a piezoresistive e-skin with high breathability and significant degradability using a double-layer sponge as the substrate and aniline tetramer as the conductive medium. The aniline tetramer is adsorbed on the fibroin/sodium alginate matrix by in situ polymerization, which is simple, rapid, and less restrictive to prepare. The developed e-skin demonstrated a wide detection range (0–20 kPa), ultra-low detection limit (0.06 Pa), fast response time (20 ms), and good stability (1000 cycles). The e-skin also has good antibacterial ability, excellent water vapor transmission rate (7.65 kg m −2 ·day −1 ), and biocompatibility, ensuring the comfort of long-term wearing. In addition, the e-skin is completely degraded into small particles after being immersed in sodium hydroxide solution for 48 h, greatly avoiding the generation of e-waste. In practical applications, e-skin responds quickly to weak stimuli and shows excellent sensing performance in human movement monitoring. This novel combination of the conductive oligomer and sponge substrate helps to promote the development of green electronics and implantable sensing devices.
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