Advanced Composites and Hybrid Materials
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2022
·Vol. 5
·期 3
·1812-1820
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IF 11.806
Zhang Dianbo,Zhang Minyue,Wang Jingwen,Sun Hongling,Liu Hu,Mi Liwei,Liu Chuntai,Shen Changyu
As a promising candidate for flexible epidermal strain sensor, the obvious resistance sensing signal drift of ionic conductive hydrogel affects its practical application significantly, and the AC impedance analysis appears to be an effective test method. Here, the rarely reported impedance sensing mechanism was investigated based on an axon-like ionic conductive hydrogel strain sensor, which is composed of cellulose hydrogel particles (CHPs) as the core sensing medium, rubber tube as the elastic cortex, and stainless steel as the electrode. Specifically, the prepared hydrogel strain sensor exhibited a negative ion concentration-dependent impedance sensing behavior, the impedance variation (△ Z / Z 0 ) and sensitivity (GF) at 400% reach 441.5 and 630.1, respectively. What is more, the AC impedance sensing behavior of the hydrogel sensor displayed good strain amplitude identifiability in a wide strain range up to 400%, ultralow detection limit (0.1% strain), excellent rate independence, and outstanding long-term fatigue resistance. Importantly, an equivalent circuit model was built, and the variation of ion transport impedance and electric double-layer capacitance at the electrode-CHPs interface during the tension process were verified to be the internal sensing mechanism. What is more, the special skin–core structure can effectively solve the dehydration problem and poor mechanical property of hydrogel, and the amounts of interfaces between adjacent CHPs are also beneficial for improving the impedance responsivity. We believe the proposed impedance response mechanism will undoubtedly provide important guidance for the design of high-performance ionic conductive hydrogel strain sensor. Graphical abstract An equivalent circuit model was proposed for explaining the impedance response mechanism of axon-like skin core–structured hydrogel strain sensor.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2022
·Vol. 38
·期 6
·1453-1460
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IF 2.726
Yi Jiaqi,Li Xiaoshuang,Cui Di,Han Lixia,Jiang Wei,Zhang Renguo,Niu Na,Chen Ligang
A novel fluorescent probe has been constructed based on fluorescence resonance energy transfer(FRET) between upconversion nanomaterials(UCNPs) NaYF 4 :Yb,Er and gold nanoparticles(AuNPs). The fluorescent “off-on” switching was formed for the detection of thiamphenicol(TAP) in egg samples. The fluorescence of UCNPs can be quenched to a certain degree by AuNPs. After adding TAP, the AuNPs generated aggregation and the fluorescence of UCNPs was recovered. The synthesized amination UCNPs and AuNPs were characterized by Fourier transform infrared spectroscopy(FTIR), UV-Vis, X-ray diffraction(XRD), energy dispersive spectrometer(EDS), and transmission electron microscope(TEM) techniques for observation and confirmation. As a model target, the detection of TAP has two linear ranges in the buffer solution within 0.01–0.1 µmol/L and 0.1–1 µmol/L using this fluorescent probe. The detection limit was obtained to be 0.003 µmol/L( S/N =3), which is favorable for trace analysis. The recovery of TAP from 98.2% to 105.3% was obtained, and the relative standard deviation(RSD) was from 2.5% to 4.3%. Furthermore, the method established in this study based on the UCNPs auto-low background fluorescence has high selectivity and strong ability to eliminate interference, which is beneficial to analyzing complex samples.
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POLYMER BULLETIN
·
2022
·Vol. 80
·期 3
·3377-3393
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IF 2.843
Liu Licheng,Dong Haijun,Yu Yingfeng,Tang Zhengming,Bai Chenyan,Feng Yanli,Chen Hongyu,Schmidt Thorsten
Many efforts have been made to develop catalysts for polyurethanes (PUs) due to their significant roles in the manufacturing process. However, it is still a long-standing technical issue to manipulate the catalytic activity and enhance the storage stability of PU precursors by using suitable catalyst. In this work, a new microcapsule thermolatent catalyst was prepared by emulsion solvent evaporation (ESE) method with a dibutyltin dilaurate (DBTDL) core and a polymeric shell. The glass transition temperature ( T g ) of polymeric shell was utilized as threshold temperature. By changing the composition of acrylate copolymers, the glass transition temperature of polymeric shell could be controlled, which further moderated the latency and catalytic activity of ESE microcapsule catalysts. Compared to DBTDL, all ESE microcapsule catalysts showed certain latency at 30 °C. The catalytic activity of ESE microcapsules was rapidly increased at 70 °C. In the ESE microcapsule catalysts, ESE1 sample exhibited excellent performance due to the suitable T g and uniform morphology. Compared to phenyl mercury neodecanoate and DBU, which are traditional thermolatent catalysts, ESE1 sample showed more excellent latency and catalytic activity.
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JOURNAL OF NANOPARTICLE RESEARCH
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2022
·Vol. 24
·期 5
·1-11
·
IF 2.533
He Jianyue,Duan Shuo,Yue Rui,Zhang Xin,Wang Qiao,Xu Lin,Liu Yan,Fang Min,Yang Qing
In this work, MoS 2 -reduced graphene oxide (rGO) composites were prepared by a simple hydrothermal reaction and characterized by SEM, Raman, XRD, and electrochemical impedance spectroscopy (EIS). The obtained MoS 2 -rGO/GCE was used for electrochemical investigation of silver nanoparticles (AgNPs) by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and chronocoulometry (CC). It was found that the MoS 2 -rGO/GCE exhibited good stability and could enhance current response of AgNP electrooxidation effectively. On the basis, a new electrochemical method was developed to detect AgNPs in aqueous solution. The proposed method exhibited satisfactory analytical performance for AgNP detection with the limit of detection (LOD) as 2.63 ng/L and the linear range from 5 to 120 ng/L. The determination assays in water samples by MoS 2 -rGO/GCE were also discussed. The assay recoveries in water samples were obtained as 94.9–99.4%. That suggested a promising application prospect in environmental analysis. Graphical abstract The MoS 2 -rGO/GCE enhanced the electrochemical response of AgNPs, which are attributed from the Ag absorbability of MoS 2 and the electrochemical signal amplification of rGO. This finding resulted in a new electrochemical approach to simple detection of AgNPs in water
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Nature Communications
·
2022
·Vol. 13
·期 1
·1-8
·
IF 17.694
Liu Chun-Yu,Yuan Shang-Fu,Wang Song,Guan Zong-Jie,Jiang De-en,Wang Quan-Ming
Copper hydrides are important hydrogenation catalysts, but their poor stability hinders the practical applications. Ligand engineering is an effective strategy to tackle this issue. An amidinate ligand, N,N′-Di(5-trifluoromethyl-2-pyridyl)formamidinate (Tf-dpf) with four N-donors has been applied as a protecting agent in the synthesis of stable copper hydride clusters: Cu 11 H 3 (Tf-dpf) 6 (OAc) 2 ( Cu 11 ) with three interfacial μ 5 -H and [Cu 12 H 3 (Tf-dpf) 6 (OAc) 2 ]·OAc ( Cu 12 ) with three interstitial μ 6 -H. A solvent-triggered reversible interconversion between Cu 11 and Cu 12 has been observed thanks to the flexibility of Tf-dpf. Cu 11 shows high activity in the reduction of 4-nitrophenol to 4-aminophenol, while Cu 12 displays very low activity. Deuteration experiments prove that the type of hydride is the key in dictating the catalytic activity, for the interfacial μ 5 -H species in Cu 11 are involved in the catalytic cycle whereas the interstitial μ 6 -H species in Cu 12 are not. This work highlights the role of hydrides with regard to catalytic hydrogenation activity.
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高影响因子
Bone Research
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2022
·Vol. 10
·期 1
·1-12
·
IF 13.362
Kong Ning,Yang Hang,Tian Run,Liu Guanzhi,Li Yiyang,Guan Huanshuai,Wei Qilu,Du Xueshan,Lei Yutian,Li Zhe,Cao Ruomu,Zhao Yiwei,Wang Xiaohui,Wang Kunzheng,Yang Pei
Core decompression (CD) with the elimination of osteonecrotic bone is the most common strategy for treating early-stage nontraumatic osteonecrosis of the femoral head (ONFH). Adjuvant treatments are widely used in combination with CD as suitable methods of therapy. Existing augmentations have to be fabricated in advance. Here, we report a novel injectable glycerin-modified polycaprolactone (GPCL) that can adapt to the shape of the CD cavity. GPCL shows great flowability at 52.6 °C. After solidification, its compressive modulus was 120 kPa at body temperature (37 °C). This excellent characteristic enables the polymer to provide mechanical support in vivo. In addition, GPCL acts as a carrier of the therapeutic agent zoledronic acid (ZA), demonstrating sustained release into the CD region. ZA-loaded GPCL was injected into ONFH lesions to treat early-stage nontraumatic cases. Compared to that in the CD group, CD+ZA-loaded GPCL injection preserved bone density and increased the collagen level in the femoral head. At the interface between the GPCL and CD tunnel wall, osteogenesis was significantly promoted. In addition, morphological evaluations revealed that the femoral heads in the CD+ZA-GPCL group exhibited improved pressure resistance. These results suggest a strategy effective to preserve the bone density of the femoral head, thus decreasing the possibility of femoral head collapse. This novel injectable polymer has, therefore, considerable potential in clinical applications.
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Journal of Coatings Technology and Research
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2022
·Vol. 19
·期 4
·1187-1198
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IF 2.339
Yuan Jiajia,Yin Xue,Qiu Zelin,Shen Yujie,Fang Lifeng,Liang Zhiying,Kong Qingran,Zhu Baoku
In this work, highly fluorinated acrylate emulsions with reliable stability emulsified by protonated octadecylamine were successfully synthesized. With appropriate protonation, the obtained emulsion showed high monomer conversions up to 90.2% and ultralow surface energy. The ultralow-surface-energy coatings were fabricated via surface enrichment of abundant fluorine and replacing hydrophilic amino groups with hydrophobic groups through the Michael addition reaction. Superhydrophobic and self-cleaning surfaces were prepared on porous substrates through dip coating. When fabricated on porous glass fiber nonwoven mats, surfaces coated with enriching fluorinated side chains and few hydrophilic groups showed remarkable superhydrophobicity with a water contact angle more than 150º and a low sliding contact angle of 4.7°. The usage of fluorinated emulsions was sharply reduced due to the addition of perfluorinated acrylate. Moreover, the Michael acceptors were alternative such as perfluorinaed acrylates, long aliphatic acrylates and crosslinking acrylates, displaying superior hydrophobicity and waterproof properties. All the results conclusively indicated that this practical modified method was promising for potential applications of hydrophobic modifications. Graphical abstract
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Nature Communications
·
2022
·Vol. 13
·期 1
·1-9
·
IF 17.694
Tang Jiayue,Zhao Yuanyuan,Wang Mi,Wang Dianyu,Yang Xuan,Hao Ruiran,Wang Mingzhan,Wang Yanlei,He Hongyan,Xin John H.,Zheng Shuang
Circadian humidity fluctuation is an important factor that affects human life all over the world. Here we show that spherical cap-shaped ionic liquid drops sitting on nanowire array are able to continuously output electricity when exposed to outdoor air, which we attribute to the daily humidity fluctuation induced directional capillary flow. Specifically, ionic liquid drops could absorb/desorb water around the liquid/vapor interface and swell/shrink depending on air humidity fluctuation. While pinning of the drop by nanowire array suppresses advancing/receding of triple-phase contact line. To maintain the surface tension-regulated spherical cap profile, inward/outward flow arises for removing excess fluid from the edge or filling the perimeter with fluid from center. This moisture absorption/desorption-caused capillary flow is confirmed by in-situ microscope imaging. We conduct further research to reveal how environmental humidity affects flow rate and power generation performance. To further illustrate feasibility of our strategy, we combine the generators to light up a red diode and LCD screen. All these results present the great potential of tiny humidity fluctuation as an easily accessible anytime-and-anywhere small-scale green energy resource.
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JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 11
·6474-6486
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IF 4.682
Ma Xi,Wang Chengyang,Guo Hanxiang,Wang Zhaofeng,Sun Nan,Huo Pengfei,Gu Jiyou,Liu Yang
Cellulose acetate (CA) is widely used in the preparation of ultrafiltration membranes due to its many excellent characteristics, especially chemical activity and biodegradability. To improve the inherent hydrophobic and antifouling properties of CA membrane, in this work, CA was successfully modified with dopamine (CA-2,3-DA) through selective oxidation and Schiff base reactions, which was confirmed by FTIR and 1 H NMR measurements. Then, CA-2,3-DA membrane with high water permeability and excellent antifouling property was prepared by the phase inversion method. Compared with the original CA membrane, the CA-2,3-DA membrane maintained a higher rejection ratio for BSA (92.5%) with a greatly increased pure water flux (167.3 L m −2 h −1 ), which could overcome the trade-off between permeability and selectivity of the traditional CA membrane to a certain extent. According to static protein adsorption and three-cycle dynamic ultrafiltration experiments, the CA-2,3-DA membrane showed good antifouling performance and superior long-term performance stability, as supported by the experimental results, including flux recovery ratio, flux decline ratio, and filtration resistance. It is expected that this approach can greatly expand the high-value utilization of modified natural organic polysaccharides in separation engineering.
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CELLULAR & MOLECULAR BIOLOGY LETTERS
·
2022
·Vol. 27
·期 1
·1-13
·
IF 8.702
Zhu Shenglong,Wang Wei,Zhang Jingwei,Ji Siyu,Jing Zhe,Chen Yong Q.
Background A comprehensive understanding of the molecular mechanisms of adipogenesis is a critically important strategy for identifying new targets for obesity intervention. Methods Transcriptomic and lipidomic approaches were used to explore the functional genes regulating adipogenic differentiation and their potential mechanism of action in OP9 cells and adipose-derived stem cells. Oil Red O staining was used to detect oil droplets in adipocytes. Results RNA sequencing (RNA-seq) showed that Slc25a5 expression was significantly upregulated in adipogenic differentiation. Depletion of Slc25a5 led to the suppressed expression of adipogenesis-related genes, reduced the accumulation of triglycerides, and inhibited PPARγ protein expression. Moreover, the knockdown of Slc25a5 resulted in significant reduction of oxidative phosphorylation (OXPHOS) protein expression (ATP5A1, CQCRC2, and MTCO1) and ATP production. The RNA-seq and real-time quantitative polymerase chain reaction (RT–qPCR) results suggested that adipogenic differentiation is possibly mediated by ERK1/2 phosphorylation, and this hypothesis was confirmed by intervention with PD98059 (an ERK 1/2 inhibitor). Conclusions This study indicates that Slc25a5 inhibits adipogenesis and might be a new therapeutic target for the treatment of obesity.
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JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 5
·3678-3687
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IF 4.682
Bai Xiao-Han,Zhang Jun,Cheng Guo-Ting,Liu Xiao-Fei,Sun Tian-Cai,Yang Jun,Cao Zhi-Kai,Ramakrishna Seeram,Long Yun-Ze
Burns on human skin often leads to slow recovery because of continuous wound infections caused by the loss of skin protection. In this study, a seed-free soaking method is put forward to prepare PCL@ZIF-8/εPL nanofibers as a dressing for burn wounds. This ZIF-8-coated polycaprolactone (PCL) fiber exhibits increased specific surface area, significantly increasing the polypeptide loading of epsilon polylysine (εPL) from 12 to 20 wt.%. The antibacterial experiment found that ZIF-8 and εPL exhibited dual antibacterial properties, and after εPL was loaded to ZIF-8, the nanofiber demonstrated stronger antibacterial properties that can better kill the remaining tenacious bacteria. This high-efficiency bactericidal property, combined with the ability to protect wounds from common infections by bacteria in the air, would promote wound healing, shortening the healing time period from 24 to 17 days. Further tissue sections confirm that the shielding effect and dual antibacterial properties of the composite fiber membrane are the reasons behind the acceleration of the healing of burns and scalds. Shielding and antibacterial material are helpful for the treatment of burns and scalds, and it may also guide the treatment of other types of wounds.
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BMC Complementary Medicine and Therapies
·
2022
·Vol. 22
·期 1
·1-14
·
IF 2.838
Luo Yiyuan,Wang Juan,Li Shuo,Wu Yue,Wang Zhirui,Chen Shaojun,Chen Hongjiang
Background Bletilla striata is the main medicine of many skin whitening classic formulas in traditional Chinese medicine (TCM) and is widely used in cosmetic industry recently. However, its active ingredients are still unclear and its fibrous roots are not used effectively. The aim of the present study is to discover and identify its potential anti-melanogenic active constituents by zebrafish model and molecular docking. Methods The antioxidant activities were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, 2,2′-azino-bis-(3-ethylbenthiazoline-6-sulphonic acid) (ABTS) radical scavenging activity and ferric reducing antioxidant power (FRAP) assay . The anti-melanogenic activity was assessed by tyrosinase inhibitory activity in vitro and melanin inhibitory in zebrafish. The chemical profiles were performed by ultra-high-performance liquid chromatography combined with quadrupole time-of-flight tandem mass spectrometry (UPLC-Q-TOF-MS/MS). Meanwhile, the potential anti-melanogenic active constituents were temporary identified by molecular docking. Results The 95% ethanol extract of B. striata fibrous roots (EFB) possessed the strongest DPPH, ABTS, FRAP and tyrosinase inhibitory activities, with IC 50 5.94 mg/L, 11.69 mg/L, 6.92 mmol FeSO 4 /g, and 58.92 mg/L, respectively. In addition, EFB and 95% ethanol extract of B. striata tuber (ETB) significantly reduced the melanin synthesis of zebrafish embryos in a dose-dependent manner. 39 chemical compositions, including 24 stilbenoids were tentatively identified from EFB and ETB. Molecular docking indicated that there were 83 (including 60 stilbenoids) and 85 (including 70 stilbenoids) compounds exhibited stronger binding affinities toward tyrosinase and adenylate cyclase. Conclusion The present findings supported the rationale for the use of EFB and ETB as natural skin-whitening agents in pharmaceutical and cosmetic industries.
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