JOURNAL OF MEMBRANE SCIENCE
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2020
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IF 7.183
Yang Wang,Jianqiang Wang,Yajie Ding,Shouyong Zhou,Fu Liu
Membrane fouling has been considered as the greatest challenge for membrane separation especially in oil/water separation process. Novel strategies for reducing membrane fouling are highly important for membrane separation. In this study, a novel membrane antifouling method in oil/water separation was proposed through in situ generated micro-bubbles. The fouling reduced process was realized by combination of membrane separation and catalytic reaction . Oxygen micro-bubbles were in situ generated by the decomposition of hydrogen peroxide (H 2 O 2 ) under the catalysis of manganese oxide nanoparticles , which were loaded on the surface of carbonized PAN (cPAN) nanofibrous membrane. In situ generated micro-bubbles significantly inhibited the surface deposition of rejected oils through hydrophobic interaction between micro-bubbles and oils. Membrane permeability was significantly reduced to 909 ± 286 Lm −2 h −1 bar −1 (3% of its initial data) after 65 min of continuous oil-in-water separation. However, it remains as high as 14755 ± 1930 Lm −2 h −1 bar −1 (67.6% of initial data) with the presence of H 2 O 2 , which was 16.2 times higher. The current study presents a potential approach to achieve continuous oil/water emulsion separation with reduced membrane fouling and advance the practical application of membranes for oil/water separation.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2020
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IF 7.489
Hong Huang,Zhangfeng Shen,Biyun Chen,Xiaoyan Wang,Qineng Xia,Zhigang Ge,Yangang Wang,Xi Li
Mitochondrial oxidative stress is associated with the occurrence and development of a wide range of human diseases. The development of methodologies to alleviate oxidative stress-mediated injury may have therapeutic potential. Herein, we report the design and preparation of triphenylphosphonium-functionalized selenium-doped carbon nanodots (TPP-Se-CDs) that can efficiently scavenging hydroxyl radicals ( OH) and superoxide anions (O 2 − ) in mitochondria region. Se-CDs with two-photon blue fluorescence were initially prepared by facile hydrothermal treatment of selenomethionine, followed by the covalent conjugation with TPP. The as-obtained TPP-Se-CDs showed high colloidal stability, strong scavenging abilities towards OH and O 2 − . Moreover, TPP-Se-CDs exhibited low cytotoxicity and mitochondria targeting ability. Taking advantages of these prominent features, TPP-Se-CDs have been successfully applied to combat H 2 O 2 and phorbol 12-myristate 13-acetate (PMA) induced oxidative stress in mitochondria.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2020
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IF 5.162
Bailiang Xue,Yang Yang,Rui Tang,Danwei Xue,Yongchang Sun,Xinping Li
Novel ternary deep eutectic solvents (DESs) were designed to efficiently dissolve the lignin for synthesizing the lignin-containing rigid polyurethane foam (LRPUF). These ternary DESs were constituted by choline chloride (ChCl), two hydrogen bond donors – glycerol (Gly) and polyethylene glycol (PEG-400). The maximum solubility of lignin in the sample DES-2 (ChCl:Gly:PEG-400 = 1:2:2) could up to 66.70 g/100 g solvent at 60 °C due to the hydrogen bonds are the main driving force, which was confirmed by the largest hydrogen bond basicity parameter β value and disappearance of crystalline peak. The main structure of the lignin did not change after dissolution in DES-2. The content of phenolic and total hydroxyl groups of the regenerated lignin increased, with reduction in their average molecular weights and polydispersity, indicating that the dissolution and regeneration of lignin in these ternary DESs can make it more homogeneous. The regenerated lignin was partially replacing for polyols in the LRPUF synthesis, the lignin replacement rate could up to 58.6% with good mechanical properties. The findings add to our understanding for efficient dissolution of lignin in DESs and for synthesizing the highly LRPUF.
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CHEMICAL RESEARCH IN TOXICOLOGY
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2020
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IF 3.184
Qingmei Li,Wei Li,Jiaxing Zhao,Xiucai Guo,Qian Zou,Zixin Yang,Ruixue Tian,Ying Peng,Jiang Zheng
2,4-Dichlorophenol (2,4-DCP), an environmental pollutant, was reported to cause hepatotoxicity. The biochemical mechanisms of 2,4-DCP induced liver injury remain unknown. The present study showed that 2,4-DCP is chemically reactive and spontaneously reacts with GSH and bovine serum albumin to form GSH conjugates and BSA adducts. The observed conjugation/adduction apparently involved the addition of GSH and departure of chloride via the ipso substitution pathway. Two biliary GSH conjugates and one urinary N-acetyl cysteine conjugate were observed in rats given 2,4-DCP. The N-acetyl cysteine conjugate was chemically synthesized and characterized by mass spectrometry and NMR. As expected, 2,4-DCP was found to modify hepatic protein at cysteine residues in vivo by the same chemistry. The observed protein adduction reached its peak at 15 min and revealed dose dependency. The new findings allowed us to better understand the mechanisms of the toxic action of 2,4-DCP.
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JOURNAL OF HAZARDOUS MATERIALS
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2020
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IF 9.038
Jun Liang,Xiaoyun Xu,Qijun Zhong,Zibo Xu,Ling Zhao,Hao Qiu,Xinde Cao
Biochar as an environmental-friendly and low-cost catalyst has gained increasing attention in the catalytic degradation of organic pollutants. However, the roles of endogenous mineral constituents in biochar in the catalytic degradation are still unclear. In this study, the mineral-rich biochar produced from sewage sludge at 400 °C (SS400) and 700 °C (SS700) and their corresponding demineralized biochar (DSS400 and DSS700) were used to be the persulfate (PS) activator for phenol degradation. Results showed that the mineral-rich biochar + PS system had negligible phenol degradation (≤12.6 %), whereas distinct degradation of phenol were obtained in the demineralized biochar + PS system where DSS400 + PS and DSS700 + PS exhibited 36.3 % and 57.8 % degradation, respectively. Different minerals in mineral-rich biochar exhibited varying functions on phenol degradation. Mg and K in biochar had less effect on the phenol degradation, while Fe-containing minerals favored the phenol degradation. However, Ca-containing minerals more greatly reduced the formation of hydroxyl radical, resulting in more inhibited degradation of phenol. Thus, the overall degradation of phenol was reduced by the mineral-rich biochar. The findings indicated that the inherent minerals in biochar were not favorable for the phenol degradation, which guides us the application of biochar containing different minerals in the remediation of organic pollutants.
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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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2020
·Vol. 64
·期 3
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IF 4.904
Zhiwei Lin,Zhangya Pu,Guangjian Xu,Bing Bai,Zhong Chen,Xiang Sun,Jinxin Zheng,Peiyu Li,Di Qu,Qiwen Deng,Zhijian Yu
This study aimed to evaluate the in vitro antimicrobial activity, heteroresistance emergence, and resistance mechanism of omadacycline (OMC) in clinical Enterococcus faecalis isolates from China. A total of 276 isolates were collected retrospectively in China from 2011 to 2015. The MICs of OMC, doxycycline (DOX), and minocycline (MIN) against E. faecalis were determined by broth microdilution. Tetracycline (TET)-specific resistance genes and multilocus sequence typing (MLST) of the isolates were investigated using PCR. The detection frequency of OMC heteroresistance in E. faecalis was evaluated with population analysis profiling (PAP). The mechanism of OMC heteroresistance and resistance in E. faecalis was examined by amplifying 30S ribosomal subunit genes, RNA sequencing (RNA-Seq), and in vitro recombination experiments. The OMC MICs of clinical E. faecalis isolates ranged from ≤0.06 to 1.0 mg/liter, and 42% of the E. faecalis isolates with an OMC MIC of 1.0 mg/liter were found to be sequence type 16 (ST16). Six OMC-heteroresistant isolates with MIC values of ≤0.5 mg/liter were detected among 238 E. faecalis isolates. The resistant subpopulations of heteroresistant isolates showed OMC MICs in the range of 2 to 4 mg/liter and were found without 30S ribosomal subunit gene mutations. Moreover, RNA sequencing and in vitro recombination experiments demonstrated that overexpression of a bone morphogenetic protein (BMP) family ATP-binding cassette (ABC) transporter substrate-binding protein, OG1RF_RS00630, facilitated OMC heteroresistance in E. faecalis. In conclusion, OMC exhibited better activity against clinical E. faecalis isolates from China than that of DOX or MIN, and overexpression of OG1RF_RS00630 in E. faecalis facilitated the development of OMC heteroresistance.
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Arabian Journal of Geosciences
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2020
·Vol. 13
·期 2
·1-13
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IF 1.327
Zou Jirui,Yue Xiangan,Dong Jie,Gu Jun,Fu Joseph Yuchun,Wang Liqi,Mou Yufan
In order to enhance the low recovery efficiency in low-permeability and heterogeneous reservoirs resulted by water channeling during water flooding process, a series of flooding experiments using in situ polymerization microsphere (ISPM) with surfactant were conducted to achieve deep profile control in high conductivity water channels. Dynamic pressure measurement showed that ISPM demonstrated good injectability and profile control effect in low-permeability core of 20.22 mD, as the plugging rate was as high as 78.99%. At the same time, the electron microscopy results showed that the ISPM could migrate deeper into the core to form microsphere clusters to block the high conductivity channels. The core flooding experiments showed that the profile control effect of the composite slug consisted of surfactant and ISPM was much better than that of just ISPM alone. The front part of the slug consisting of BA with strong emulsifying capability and ultra-low interfacial tension can better exert the profile control effect of the ISPM and expand the sweep volume of the subsequent displacing agent better than surfactant TS with ultra-low interfacial tension. As a subsequent oil displacing agent after ISPM + BA profile control, surfactant BA with strong emulsifying capability and ultra-low interfacial tension, compared with AES and TS, achieved higher recovery efficiency. In low-permeability and heterogeneous reservoirs, ultra-low interfacial tension is screening crucial characteristic of surfactant, but emulsification capacity also plays a very important role. Combination of surfactant BA and ISPM could fully utilize the profile control effect of ISPM and the oil stripping effect of surfactant; the stage recovery efficiency was as high as 22.52%.
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Journal of Physical Chemistry C
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2020
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IF 4.189
Darvaish Khan,Jianxin Zou,Subrata Panda,Wenjiang Ding
Improving desorption kinetics and achieving thermodynamic destabilization of MgH2 is of great importance for its practical applications. In the present study, a MgH2–In composite was synthesized through high-energy ball milling of MgH2 and In, and microstructures; hydrogen ab/desorption properties of the composite were carefully investigated with respect to the identically processed pure MgH2. The thermodynamic destabilization of MgH2 was achieved through reversible phase transformation of Mg(In) solid solution due to the partial solubility of In in Mg lattice (11 atom %), which resulted in lower enthalpy values and reduced desorption temperatures. X-ray diffraction peak analysis revealed the presence of internal stress/strain fields caused by the lattice mismatch between Mg and indium, which could play an important role in improving the desorption properties of the composite. Hydrogen evolution of the MgH2–In composite was directly observed via an in situ high-resolution transmission electron microscope (TEM), which shows the “hydrogen pump” effect of a Mg3In phase which is stable only under a hydrogen environment. The formation mechanism of the Mg3In phase and its role as “hydrogen pump” in the improvements of desorption kinetics are thoroughly discussed based on the TEM observations and density functional theory (DFT) calculations.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2020
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IF 3.99
Ji Guo,Zhongli Ji
The filtration efficiency of coalescent filter elements used in gasoline and diesel oil dehydration in refineries is unsatisfactory and not sufficient to meet downstream water-content requirements. Thus, it was necessary to improve the internal filter medium of traditional oil-water coalescent filter elements. Zeolite membrane is a kind of material with superhydrophilicity and strong adsorption for and permeability to water. In this study, ZSM-5 zeolite membrane with superhydrophilic properties was successfully prepared by an in situ hydrothermal synthesis. Two experiments with zeolite membranes were performed, including membrane filtration and membrane coalescence tests. Membrane filtration tests showed that it possessed strong adsorption for and permeability to water and that the oil-water filtration efficiency for 32 # turbine oil, kerosene, and corn oil were all >95 %. In the second part of this study, composite filtration was carried out using the membrane as well as hydrophilic glass fiber and hydrophobic polypropylene (PP) membranes. Membrane coalescence test demonstrated that, when the oil contained a phenol/water combination, the water rejection rate of the composite filtration with ABACBA (A, PP fiber; B, glass fiber; and C, molecular sieve membrane) was 90.8 %, with the downstream water content controlled within 100 mg/L and the quality factor increased from 0.18 to 0.23, relative to other systems. These experimental results showed potential for improving the current oil-water coalescent filters.
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LASER PHYSICS
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2020
·Vol. 30
·期 6
·065602
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IF 1.333
Lili Kong,Meizhen Huang,Jie Chen,Mengshi Lin
In this study, a rapid, stable, and sensitive colorimetric/surface-enhanced Raman spectroscopy (SERS) method was developed based on a polyvinyl alcohol‐decorated Au nanoparticle (PVA–Au) colloid for thein situ detection of thiram residues in fruits and vegetables. The PVA–Au colloid acted as both a colorimetric and SERS sensor. The colorimetric detection of thiram is based on the color change and absorption band shift caused by aggregation of the PVA–Au colloid. The stable and controllable colorimetric process has been verified. The influence of the media pH and reaction time on the aggregation of the PVA–Au colloid were also investigated. The reflectance and SERS spectra of the thiram samples were acquired and analyzed. The limit of the colorimetric detection of thiram in apples, pears, and vegetables was 4.62, 7.83, and 10.74 ppb (μg kg−1), respectively, which is well below the maximum residue level of 5 ppm (mg kg−1) set by the National Food Safety Standard of China and the US Environmental Protection Agency. Meanwhile, rapid, in situ, and non-invasive SERS detection was used to acquire SERS spectra of thiram residues based on the localized surface plasmonic resonance effect of the PVA–Au colloid. The naked-eye visible and stable colorimetric detection is suitable for the rapid detection of pesticide residues in a large number of plant samples, while the positive results could be further confirmed and verified by SERS. The results demonstrate that this colorimetric/SERS method has great potential to detect thiram residues in real foods and improve the detection efficiency.
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SENSORS AND ACTUATORS B-CHEMICAL
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2020
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IF 7.1
Riyue Dong,Yuying Yao,Dongna Li,Haoran Zhang,Wei Li,Maxim Molokee,Yingliang Liu,Bingfu Lei
A silicon oxide quantum dots (Si-O QDs) and Ag nanoclusters hybrid nanosensing probe with dual-emission and small nanocrystals that acts as an “off-on” ratio fluorescent probe for hydrogen peroxide (H 2 O 2 ) detection was developed. The probe was used to measure the H 2 O 2 concentration generated by mitochondria in vitro via recording the I 455 /I 680 fluorescence ratio. Furthermore, this hybrid probe was applied to monitor the wound-induced H 2 O 2 in lettuce leaf, and realized the visualized fluorescence qualitative detection H 2 O 2 in vivo via laser scanning confocal microscope. The working mechanism of the probe is also investigated. Inner filter effect (IFE) estimation, Fourier transform infrared (FTIR) spectra and high-resolution transmission electron microscopy (HRTEM) images were applied to study the quenching mechanism and recovering reason of Si-O QDs fluorescence. The results show that the blue fluorescence of Si-O QDs can be quenched by Ag NCs via the IFE and fluorescent resonance energy transfer (FRET) effect. After adding H 2 O 2 , the surface groups of Ag NCs was changed and the IFE and FRET effects between the Si-O QDs and Ag NCs are disabled, thus the quenched Si-O QDs luminescence can be regularly recovered.
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PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
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2020
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IF 2.169
Lijun Zhen,Qiuyu Wei,Qilong Wang,Huiyun Zhang,Michael Adu-Frimpong,Caleb Kesse Firempong,Ximing Xu,Jiangnan Yu
6-Gingerol, an active herbal ingredient of ginger has various bioactivities such as anti-neurodegenerative disease, anti-inflammatory and so on. The aim of the present study was to enhance the oral bioavailability and brain distribution of 6-Gingerol via polymeric micelles. A polymeric micelles drug delivery system of 6-Gingerol consisting of D-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) and Poly (ethylene glycol)-poly (ε-caprolactone) (PEG-PCL) was prepared via solvent injection method. The developed 6-Gingerol-loaded TPGS/PEG-PCL micelles (6-GTPMs) were characterized based on particle size, polydispersity index (PDI), zeta potential, encapsulation efficiency (EE), drug loading (DL) and in vitro release profile. The pharmacokinetics and tissue distribution studies were also evaluated. The nanoformulation produced a particle size of 73.24 ± 2.84 nm with acceptable PDI (0.129 ± 0.03), zeta potential (−2.74 ± 0.92 mV), DL (4.64%) and EE (79.68%). The in vitro release profile showed that the 6-GTPMs enhanced the solubility of 6-Gingerol, while the pharmaceutical analysis in rats indicated that 6-GTPMs significantly improved the oral bioavailability of 6-Gingerol (about 3 folds) in circulation. The 6-GTPMs exhibited remarkable brain targetability in the tissue distribution analysis. Collectively, a 6-Gingerol polymeric micelle with enhanced oral bioavailability coupled with excellent brain distribution was successfully developed.
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