International Journal of Nanomedicine
·
2023
·
IF 8
Shaohui Zheng,Min Zhang,Hongyan Bai,Meijuan He,Lina Dong,Lulu Cai,Mingming Zhao,Qi Wang,Kai Xu,Jingjing Li
Background Early diagnosis of renal cell carcinoma is extremely significant for the effective treatment of kidney cancer. The development of AS1411 aptamer modified Mn-MoS2 QDs provides a promising fluorescence/magnetic resonance (MR) dual-modal imaging probe for the precise diagnosis of renal clear cell carcinoma.Methods In this work, Mn-MoS2 QDs were synthesized through a simple “bottom-up” one-step hydrothermal method. AS1411 aptamer was modified on the Mn-MoS2 QDs to improve the specificity to renal cell carcinoma. The characteristics of Mn-MoS2 QDs were confirmed by transmission electronic microscopy (TEM), atomic force microscope (AFM), X-ray photoelectron spectrometer (XPS), photoluminescence (PL) emission spectra, etc. Cellular fluorescence labelling was investigated using the Mn-MoS2 QDs and AS1411-Mn-MoS2 QDs. The T1-weighted MR imaging was assessed by the in vitro MR cell imaging and in vivo MR imaging. Finally, the long-term toxicity of Mn-MoS2 QDs was investigated by the hematology and histological analysis.Results The prepared Mn-MoS2 QDs exhibited excellent aqueous property, intense fluorescence, low toxicity, high quantum yield of 41.45% and high T1 relaxivity of 16.95 mM−1s−1. After conjugated with AS1411 aptamer, the AS1411-Mn-MoS2 QDs could specifically fluorescently label the renal carcinoma cells and present a specific MRI signal enhancement in the tumor region of mice bearing renal carcinoma tumors. Furthermore, Mn-MoS2 QDs revealed low toxicity to the mice via hematology and histological analysis.Conclusion These results demonstrated the potential of AS1411-Mn-MoS2 QD as a novel nanoprobe for targeted MR imaging and fluorescence labelling of renal cell carcinoma.
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PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2018
·
IF 6.735
Jinhong Fan,Hehe Qin,Simin Jiang
Peroxymonosulfate (PMS) is an alternative to hydrogen peroxide in advanced oxidation processes. Herein, we present a simple one-pot synthetic approach for the Mn-doped graphite phase carbon nitride (g-C 3 N 4 ) materials and make it as a catalyst to activate PMS for acetaminophen (ACT) degradation. Fabricated Mn-g-C 3 N 4 composites (MnCN) were characterized by SEM, EDS, XRD, XPS, and FTIR. Results showed that Mn was uniformly dispersed in the structure of g-C 3 N 4 mostly in the form of Mn-N coordination. The effects of pH, contents of doped Mn, catalyst dosage, and reusability of catalyst and corresponding kinetic study were conducted to determine the catalytic performance of MnCN. High reaction efficiency was obtained in a wide pH range of 3.2–9. 100% removal of ACT in 15 min under optimized conditions with initial pH 6.5, 0.8 g/L of PMS and 200 mg/L of catalyst of 0.5-MnCN. Additionally, the reaction mechanism of the PMS/MnCN system was investigated using the electron spin resonance technique, quenching studies as well as different organics with electron-donating or electron-withdrawing groups. No PMS decomposition was detected without substrates. No inhibition effect by ethanol or tert -Butyl alcohol and complete inhibition effect by benzoquinone and partly by furfuryl alcohol, as well as ESR spectrum of TEMP- 1 O 2 were observed, suggesting that the activation of PMS proceeded in a new way, which is different from traditional sulfate radical-based advanced oxidation processes. A possible mechanism was proposed for ACT removal. PMS was first bounded to Mn-N sites to generate the superoxide anion. Then singlet oxygen produced by superoxide anion would react with ACT by replacing the electron-donating group of acylamino.
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WATER RESEARCH
·
2019
·
IF 7.913
Ling Li,Cui Lai,Fanglong Huang,Min Cheng,Guangming Zeng,Danlian Huang,Bisheng Li,Shiyu Liu,MingMing Zhang,Lei Qin,Minfang Li,Jiangfan He,Yujin Zhang,Liang Chen
This study investigated the hydrogen peroxide (H 2 O 2 ) activation potential of Fe–Mn binary oxides modified bio-char (FeMn/bio-char) for the degradation of naphthalene , the dominant PAHs in drinking water . Results showed that FeMn/bio-char exhibited 80.7- and 2.18-times decomposition rates towards H 2 O 2 than that of pure bio-char and Fe–Mn binary oxides, respectively, and consequently the FeMn/bio-char/H 2 O 2 photo-Fenton system presented highest naphthalene removal efficiency. The enhanced catalytic activity could be ascribed to the synergistic effect of the combination of bio-char and Fe–Mn binary oxides, such as promoting the adsorption capacity towards contaminant, increasing concentration of persistent free radicals (PFRs) and introducing Fe–Mn binary oxides as new activator. According to the batch-scale experiments, FeMn/bio-char/H 2 O 2 photo-Fenton system could degrade naphthalene effectively at a wide pH ranges, and 82.2% of naphthalene was degraded under natural pH of 5.6 within 148 min. Free radicals quenching studies and electron spin resonance (ESR) analyses verified that the dominant free radical within FeMn/bio-char/H 2 O 2 photo-Fenton system was hydroxyl radical (•OH). According to the preliminary analysis, the generation of •OH were ascribed to the activation of H 2 O 2 by Fe (II), Mn (II) and PFRs on the catalyst surface. The mainly degradation intermediates of naphthalene were identified by GC-MS analysis. Consequently, the possible degradation pathways were proposed. Moreover, naphthalene degradation experiments were also conducted in river, tap water , industrial wastewater as well as medical wastewater, and the results indicated that the FeMn/bio-char/H 2 O 2 photo-Fenton system was effective in the treatment of naphthalene in natural waters. This study brings a valuable insight for the potential environmental applications of modified bio-char.
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高影响因子
APPLIED CATALYSIS A-GENERAL
·
2019
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IF 4.63
Liu Zhong,Qingyan Fang,Xin Li,Quan Li,Cheng Zhang,Gang Chen
Various catalysts were synthesized by the redox-precipitation (RP) and co-precipitation (CP) methods, and their catalytic performances for the complete catalytic oxidation of lean methane combustion were investigated. The synthetic catalysts were characterized by BET, XRD, Raman, XPS, TG, UV–vis and H2-TPR. MnCe-RP showed 50% methane conversion to CO 2 at ˜446 °C, which was 23 °C lower the temperature required for MnCe-CP. The active components (K x Mn 8 O 16 ) in the bulk and on the surface of MnCe-RP were confirmed. The redox-precipitation method synthesized open nanorod and nanosphere catalysts containing K x Mn 8 O 16 and Mn 5 O 8 , whereas the co-precipitation method synthesized agglomerate catalysts containing only Mn 5 O 8 . The higher surface-concentrations of Mn 4+ , Ce 3+ and O α on MnCe-RP are beneficial for its higher catalytic performance. Furthermore, the optical bandgap value of MnCe-RP is lower than that of MnCe-CP, and the K ion in K x Mn 8 O 16 may weaken the Mn-O bond, improving the catalyst reducibility, especially for the reduction process of Mn 3 O 4 →MnO.
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Nano Research
·
2019
·Vol. 12
·期 7
·1733-1738
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IF 8.515
Dong Lvming,Chen Zhuo,Ye Lei,Yu Yan,Zhang Jianbing,Liu Huan,Zang Jianfeng
Mn-doped all-inorganic perovskite quantum dots (QDs) provide prominent applications in the fields of low-cost light source or display, because of their remarkable properties including dual-color emission and reduced lead content, as well as high photoluminescence quantum yields (PLQYs) and high stability. However, the existing synthesis approaches usually require hash conditions, such as high temperature and nitrogen protection, which is a major hurdler for the practical manufacturing. In addition, the significantly high Mn substitution ratio in CsPbX 3 QDs is still challenging. The real dual-color emission with two strong emission peaks in the Mn-doped all-inorganic perovskite QDs has attracted great interest. Here we present a gram-scale approach to synthesize both CsPb x Mn 1− x Cl 3 and CsPb 1− x Mn x Cl y Br 3− y QDs at 100 °C in the air with high Mn substitution ratio, up to 55.64% atomically. The as-prepared CsPb 1− x Mn x Cl y Br 3− y QDs exhibit high PLQYs of 62.41% and dual-color emission with two strong emission peaks around at 400–450 nm and 600 nm, respectively. The enhanced peak at 400–450 nm is a result of the hybrid halides in CsPbBr x Cl 3− x host. Furthermore, the unique advantage of the optical emission and high PLQYs properties of the CsPb x Mn 1 − x Cl 3 QDs has been demonstrated as invisible ink for encryption applications and polymer composites. Our gram-scale synthesis approach for Mn-doped all-inorganic perovskite QDs may boost the future research and practical applications of QDs-based white LED, spintronics, and molecular barcoding.
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TRANSACTIONS OF TIANJIN UNIVERSITY
·
2018
·Vol. 24
·期 4
·361-369
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IF 0
Zhang Xubin,Dong Jianxin,Hao Zhencheng,Cai Wangfeng,Wang Fumin
Active Fe- and Mn-loaded MCM-41 (Fe–Mn/MCM-41), which was synthesized via a hydrothermal reaction followed by impregnation, is used in the heterogeneous Fenton reaction to degrade methyl orange (MO) in aqueous solution. The synthesized samples were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, N 2 adsorption–desorption isotherm analysis, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy. Compared with Fe/MCM-41 and Mn/MCM-41, Fe–Mn/MCM-41 showed higher activity for MO degradation and mineralization. Effects of various operating parameters, such as pH, Mn content, and H 2 O 2 dosage, on the degradation process were subsequently investigated. Results of experiments on the effect of radical scavengers revealed that the degradation of MO could be attributed to oxidation by HO·. The synergy of Fe and Mn species in the Fenton oxidation process was also explained.
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Applied Sciences-Basel
·
2018
·Vol. 8
·期 1
·95
·
IF 1.689
Chengzhi Wang,Cheng Zhang,Yonggang Zhao,Xin Yan,Peng Cao
Honeycomb cordierite-based Mn–Ce/Al2O3catalysts were prepared by the impregnation method and used for low-temperature selective catalytic reduction (SCR) of NOxwith NH3, with and without SO2and/or H2O in a homemade fixed-bed tubular reactor. The catalyst reached nearly 80% NOxconversion at 100 °C in the absence of SO2. However, SO2reduces the catalytic activity (80% to 72%) of the honeycomb cordierite-based Mn–Ce/Al2O3catalysts under identical conditions. This finding demonstrated that the catalyst exhibited high activity at low temperature and excellent SO2resistance in the presence of 50 ppm SO2. The fresh and sulfated honeycomb cordierite-based Mn–Ce/Al2O3catalysts were characterized by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), N2adsorption–desorption, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), thermogravimetry and differential thermal analysis (TG-DTA), and Fourier transform infrared (FT-IR) spectroscopy. Characterization results indicated that the deactivation by SO2was primarily the result of the deposition of ammonium hydrogen sulfate and sulfated CeO2on the catalyst surface during the SCR process. The formed sulfates depressed the catalytic activity via the blocking of pores and the occupation of active sites. Additionally, the competitive adsorption between SO2and NH3always decreased the catalytic activity.Keywords:Mn–Ce/Al2O3catalyst;low temperature selective catalytic reduction;honeycomb cordierite;SO2resistance
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SEPARATION AND PURIFICATION TECHNOLOGY
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2018
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IF 3.927
Xiaoyong Yang,Fengping Jie,Bingjie Wang,Zhishan Bai
Environmental pollution by industrial effluents polluted with hazardous heavy metals has great concern. A novel microemulsion system (sodium dodecanoate/pentan-1-ol/heptane/NaCl) was prepared for the treatment of cobalt (Co) and manganese (Mn) wastewater. The effects of the batch extraction conditions were systematically studied and the extraction efficiency of Co(II) and Mn(II) were 98.2% and 97.5% respectively at the optimal conditions. Utilizing the centrifugal reinforcement of the annular centrifugal extractor (ACE), the continuous extraction of cobalt and manganese wastewater by microemulsion could be achieved. Under the optimized operation conditions: the motor speed of 1988 rpm, a flow ratio of 1/5, and a total flow rate of 48 L/h, the maximum extraction efficiency reached up to 99.9% for Co(II) and 99.1% for Mn(II), respectively. The stripping of Co(II) and Mn(II) from the microemulsion phase was also conducted using hydrogen chloride solution, indicating a high stripping efficiency. The investigation of synergistic extraction with microemulsion and ACE proposed an efficient treatment for Co and Mn wastewater.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2018
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IF 5.667
Dongxia Li,Jin Qin,Qiang Xu,Guiqin Yan
A convenient and efficient biosensor for detection of alkaline phosphatase (ALP) activity was built with Mn-ZnS quantum dots (QDs) as the phosphorescent probe and adenosine 5′-monophosphate (AMP) as the substrate. Eu 3+ , which could coordinate with surface carboxyl group of Mn-ZnS QDs, was added into Mn-ZnS QDs to form Mn-ZnS QDs/Eu 3+ nanocomposites, which quenched the RTP of Mn-ZnS QDs through photoinduced electron-transfer (PIET). After ALP and AMP were added into the system, under the hydrolytic catalysis of ALP, AMP was rapidly converted into adenosine and phosphate ions. The higher affinity of phosphate ions to Eu 3+ than QDs resulted in the formation of a more stable composite, and subsequently, Eu 3+ was desorbed from the surfaces of Mn-ZnS QDs, which restored the RTP of Mn-ZnS QDs. Under the optimal conditions, the RTP intensity of the Mn-ZnS QDs (ΔRTP) was well linearly related to the logarithm of the ALP activity, with a detection range of 0.15－18 U L −1 and a detection limit of 0.065 U L −1 . This phosphorescent sensor avoided interference from autofluorescent and scattering light in real biological samples and was highly sensitive to ALP.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2016
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IF 3.014
Silin Li,Hengyong Tu,Feng Li,Muhammad Tuoqeer Anwar,Lijun Yu
In order to improve the performance of intermediate temperature solid oxide fuel cells (IT-SOFCs), the effect of partial substitution of the transition metal M = Co, Cu, Fe and Mn for Ni in Nd 2 NiO 4+δ on the crystal chemistry, electrical conductivity , thermal stability, chemical reactivity with YSZ electrolyte and electrochemical performance has been systematically investigated. The electrochemical performances of the cathode materials are tested on planar NiO-YSZ anode-supported cells fabricated with YSZ as electrolyte in size of 50 mm × 50 mm. Compared to Nd 2 NiO 4+δ , each Nd 2 Ni 0.9 M 0.1 O 4+δ material shows a decrease in electrical conductivity and an increase in lattice volume, oxygen vacancy concentration and chemical reactivity with YSZ electrolyte. The cell with Nd 2 Ni 0.9 Co 0.1 O 4+δ cathode achieves the maximum power density of 530 mW cm −2 at 0.7 V at 800 °C. The cell with Nd 2 Ni 0.9 Cu 0.1 O 4+δ cathode is the most stable in short-term test. A small amount of B-site doping in Nd 2 NiO 4+δ does not cause any change in the cathode microstructure. The study demonstrates that a tradeoff between oxygen transport properties and electrical conductivity can be accomplished by appropriate selection of transition metal and level of cation B-site doping in Nd2NiO4+δ. Nd2Ni0.9M0.1O4+δ (M = Co, Cu) can be considered to be potential cathode materials in IT-SOFCs.
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JOURNAL OF LUMINESCENCE
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2014
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IF 2.367
Xiao Wei,Zhiping Zhou,Jiangdong Dai,Tongfan Hao,Hongji Li,Yeqing Xu,Lin Gao,Jianming Pan,Chunxiang Li,Yongsheng Yan
In this paper, a simple procedure for the determination of 2,4,5-trichlorophenol (2,4,5-TCP) is reported. Mn-doped ZnS quantum dots (QDs) capped by molecularly imprinted polymers (MIPs) were prepared. MIPs were characterized by spectrofluorometer, UV–vis spectrophotometer , X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), transmission electron microscope (TEM) and scanning electron microscope (SEM). Meanwhile, spectrofluorometer was used to the evaluation of optical stability, the effect of pH, and the selective and sensitive determination of 2,4,5-TCP. Under optical conditions, MIPs-capped Mn-doped ZnS QDs were successfully applied to the detection of 2,4,5-TCP in water selectively and sensitively, and a linear relationship was obtained to cover the concentration range of 5.0–50 μmol L −1 with a correlation coefficient of 0.9913. Moreover, 2,4,5-TCP could quench the room temperature phosphorescence of MIPs-capped Mn-doped ZnS QDs in a concentration-dependent manner, which was best described by a Stern–Volmer-type equation.
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高影响因子
RSC Advances
·
2016
·Vol. 6
·期 111
·109386-109393
·
IF 3.289
Jian-Jun Shi,Lei Gong,Yan-Hong Zhang,Ping Yang,Jie He
A series of Cu and Mn doped glutathione (GSH)–ZnS polypeptide quantum dots (QDs) were successfully prepared by a facile one-pot microwave-assisted sonochemical synthesis approach. Herein, GSH acted as a sulfide source and dispersant, as well as a reducing agent to form polypeptide QDs. The products were characterized by high-resolution transmission electron microscope (HRTEM) and energy dispersive spectroscopy (EDS). Results show that the size of the polypeptides QDs was 2–3 nm. In Fourier transform infrared (FT-IR) spectra, the splitting of S–H bonds and substitution by S–Zn can be noticed. The bonding interaction between Cu, Mn and Zn ions toward S was further confirmed from X-ray photoelectron spectroscopy (XPS) analysis. The results confirmed the partial Cu(Mn) substitution of Zn. Fluorescence (FL) spectra and UV-vis absorption spectra were used to investigate the optical properties. It was found that the doping of Cu and Mn could decrease the band gap of GSH–ZnS from 3.67 eV to 2.86 eV. The photoelectrochemical (PEC) properties of GSH–ZnS were enhanced due to the doping of Cu and Mn which has excellent chemical stability. The possible photoelectrochemical reaction mechanism is discussed.
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