POLYMER
·
2025
·
IF 4.5
Yajie Ding,Hua Ma,Chaoze Ji,Dingxiang Wei,Hongzhou Shang,Lihua Liu,Ning Qiao
A pH and temperature dual-responsive KGM/P(NIPAM-CA) hydrogel drug carrier was prepared by using natural polysaccharide konjac glucomannan (KGM), pH-sensitive monomer crotonic acid (CA), and temperature-sensitive monomer N-isopropylacrylamide (NIPAM). The effect of mass ratio of NIPAM to KGM on the properties of KGM/P(NIPAM-CA) hydrogels was studied by a range of testing methods. The drug loading and release properties of KGM/P(NIPAM-CA) hydrogel were investigated using 5-fluorouracil (5-FU) as a model drug. Results show that KGM/P(NIPAM-CA) exhibits good swelling and mechanical properties determined by its composition. As a drug carrier KGM/P(NIPAM-CA) hydrogel demonstrated a maximum encapsulation efficiency of 30.17% and a maximum drug loading capacity of 54.41% for 5-FU at 25°C. In simulated colonic fluid (SCF) at 25°C, the cumulative drug release rate of KGM/P(NIPAM-CA) reached 58.86% within 48 hours, which was 1.8 times higher than that in simulated gastric fluid (SGF). Furthermore, the hydrogel demonstrated biocompatibility, with a hemolysis rate of less than 3% and a cell viability exceeding 90%. These results establish KGM/P(NIPAM-CA) as a promising, biocompatible platform for stimuli-responsive, colon-targeted drug delivery.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL PHYSICS LETTERS
·
2024
·
IF 2.8
Ting-ting Yan,Yi-fei Xu,Dong-yang Xi,Zhiqing Yu,Long Ma,Dan-dan Zhang,Ran Jiang
The study investigated the behavior of N-nitropyrazole (1-NP, C 3 H 3 N 3 O 2 ) under high pressure using a diamond anvil cell, Raman spectroscopy, and simulation calculations. The pressure–volume relationship of the sample, molecular interactions, and changes in optical Raman were analyzed. The Raman experiments revealed abnormal vibration intensities and a discontinuity in peak position at 2.2 GPa. For instance, the C-H stretching vibration produces a new vibration peak under pressure, and the NO 2 torsion mode continues to red shift beyond 2.2 GPa. These observations suggest that the crystal’s phase transition results from the distortion of its hydrogen-bonded network structure. The pressure relief experiment confirms the reversibility of the phase transition.
✓ 已验证
DOI
高影响因子
Journal of Analysis and Testing
·
2019
·Vol. 3
·期 3
·277-285
·
IF 0
Li Xinxue,Huang Qingwei,Li Wei,Zhang Jinli,Fu Yan
Abstract N -Acety-L-cysteine (NAC), enriched with multiple electron-rich groups involving –SH, –C=O, and –COOH, exhibits strong affinities to transition metal ions. Herein, NAC was adopted as the stabilizing agent to synthesize a series of peroxidase-like Pt nanoclusters (NCs) with different physicochemical properties. Both the cluster size and the charge state of NAC–Pt NCs are highly dependent upon the molar ratio of [K 2 PtCl 4 ]/[NAC], contributing to different peroxidase mimicking activities. The most active Pt nanozyme (~ 1.7 nm), composed of 60% metallic Pt 0 and 40% positively charged Pt 2+ respectively, exhibits the K m of 0.132 mM for 3,3′,5,5′-tetramethylbenzidine and 35 mM for H 2 O 2 . Based on the heparin-activated enzymatic activity of NAC–Pt at pH 6.0, an ultrasensitive test was established for quantitative determination of heparin, giving the linear response of 0.5–20 μg/mL as well as the limit of detection of 2 × 10 −3 μg/mL. This proposed method is also applicable in biological fluid for practical applications. Such a colorimetric method possesses several advantages involving high sensitivity, short response, eco-friendly synthesis, low consumption of material and energy, free of expensive instrument, as well as simple operation. Graphic abstract
✓ 已验证
DOI
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Qingping Xin,Zhaoqi Qu,Xinghui Zhang,Xingwei Wang,Jiaxin Wu,Dengdi Wu,Wei Huang,Mengke Wang,Ningning Gao,Xiaoli Ding,Yuzhong Zhang
Composite membranes, which consist of a multi-layer membrane structure comprising an ultra-thin dense separation layer and a porous support layer, are used for gas separation. However, issues such as poor adhesion between layers often arise. In this study, a novel reverse-induced diffusion method was employed to achieve the in situ growth of a covalent organic framework COF (TaPa-1) on one side of polyacrylonitrile (PAN) at room temperature, resulting in the formation of a tightly bonded gutter layer. Subsequently, a metal-organic framework MOF (NH 2 -ZIF-8) was secondarily grown in situ on the TaPa-1 membrane to prepare a PAN/COF-MOF composite membrane with stable interlayer bonding. The TaPa-1 layer, with high gas permeability, and the NH 2 -ZIF-8 layer due to sheltering effect, with high gas selectivity, act synergistically to enable efficient gas sieving and rapid transport. When treating simulated flue gas (CO₂/N₂ = 1:4), the gas separation selectivity of the PAN/COF-MOF composite membrane reach 29.9, with a CO₂ permeability of 825 GPU, achieving excellent CO₂ separation performance. In this study, the PAN/COF-MOF composite membrane is constructed using the reverse-induced diffusion method, achieving stable interlayer bonding and synergistic separation, demonstrating excellent CO₂ permeability and selectivity.
✓ 已验证
产品关联
DOI
高影响因子
FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES
·
2025
·
IF 1.8
Ye Xing,Ya-nan Wang,Shimin Dang,Weichuang Ye,Hai-chao Li
In this paper, N-doped carbon nano-hollow cubes (CNHCs) were successfully prepared for the first time by a salt separation strategy, which breaks through the morphological limitations of traditional hollow structures such as spherical or tubular. This study combines β-cyclodextrin (β-CD) with CO(NH2)2 to exploit the high-temperature stability of NaCl crystal. Precise modulation of the material morphology was achieved by high-temperature carbonisation (700 °C) of the self-assembled precursor and subsequent aqueous washing to remove the salt template. This study provides a novel salt separation strategy for the morphology design and functionalisation of carbon nanomaterials and expands the preparation of complex hollow structures.
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
·
2024
·
IF 4.2
Cunxin Wei,Zhangbin Song,Yan Liu,Bin Zhang,Shasha Song,Luchang Qin,Zengdian Zhao
Nitrogen doped quaternary metal sulfide Cu 6 Fe 2 SnS 8 (CFTS) was prepared by magnetic grinding. The mechanochemical method has the advantage of simple synthesis of non-metallic doped polymetallic sulfides, and there is no solvent involved in the reaction process, which is very environmentally friendly. Non metallic doping can form electron capture centers on semiconductors, suppress the recombination of photo generated electron hole pairs, and extend electron lifetime. Moreover, doping N element into the CFTS lattice will lead to the formation of new energy states, thereby narrowing the energy band gap. The characterizations of XPS and EDS have proven the successful doping of N element into CFTS. In addition, the photocatalytic mechanism and the stability of the N-doped CFTS (N-CFTS) were studied through active substance capture experiments and cyclic experiments. The experimental results indicate that ·O 2 − is the main active substance in the degradation of MB by N-CFTS. After multiple cyclic experiment, the N-CFTS catalytic material still exhibits good crystal structure and photocatalytic stability. This photocatalytic material has great potential for applications in wastewater treatment and environmental remediation.
✓ 已验证
DOI
高影响因子
APPLIED CATALYSIS A-GENERAL
·
2022
·
IF 5.723
Ruoxuan Liang,Jiwei Li,Yaowei Wang,Zhaoxia Zhang,Bo Luan,Jianjun Liu,Shuya Qian,Shaolong Wan,Deming Zhao,Haifeng Xiong,Shuai Wang,Jingdong Lin,Yong Wang
Oxidative dehydrogenation (ODH) of n-hexane to olefins provides an alternative strategy for efficient utilization of n-hexane. Here, we report that hexagonal boron nitride (h-BN) is selective in ODH of n-hexane, achieving 89.6 % selectivity to olefins at n-hexane conversion of 16.3 % and 550 °C. We found that low temperatures and oxygen rich conditions favor the selective hydrogen abstraction from C-H bond over the cleavage of C-C bond, and the presence of gas phase free radical greatly improves the reaction rate of ODH of n-hexane over h-BN. In addition, an anomalous seagull type of relationship exists between the conversion of n-hexane and reaction temperature, which may be related to the re-distribution of the active sites.
✓ 已验证
DOI
高影响因子
PLASMA SCIENCE & TECHNOLOGY
·
2022
·Vol. 24
·期 4
·044008
·
IF 1.842
Yufa ZHOU,Jingsen ZHANG,Guangqing XIA,Yue HUA,Yanqin LI,Jixiang HU,Xiuling ZHANG,Lanbo DI
In this work, N-doped graphite oxide (GO-P) was prepared by cold plasma treatment of GO using a mixture of NH3 and Ar as the working gas. When the ratios of NH3:Ar were 1:2, 1:3, and 1:4, the specific capacitances of the GO-P(NH3:Ar = 1:2), GO-P(NH3:Ar = 1:3), and GO-P(NH3:Ar = 1:4) were 124.5, 187.7, and 134.6 F·g−1, respectively, which were 4.7, 7.1, and 5.1 times that of GO at the current density of 1 A·g−1. The capacitance retention of the GO-P(NH3:Ar = 1:3) was 80% when it was cycled 1000 times. The characterization results showed that the NH3 cold plasma could effectively produce N-doped GO and generate more active defects. The N/C ratio and the contents of pyridinic nitrogen and graphitic nitrogen of the GO-P(NH3:Ar = 1:3) were the highest. These were conducive to providing pseudocapacitance and reducing the internal resistance of the electrode. In addition, the ID/IG of the GO-P(NH3:Ar = 1:3) (1.088) was also the highest, indicating the highest number of defects. The results of discharge parameters measurement and in situ optical emission spectroscopy diagnosis of NH3 plasma showed that the discharge is the strongest when the ratio of NH3:Ar was 1:3, thereby the generated nitrogen active species can effectively promote N-doping. The N-doping and abundant defects were the keys to the excellent electrochemical performance of the GO-P(NH3:Ar = 1:3). NH3 cold plasma is a simple and rapid method to prepare N-doped GO and regulate the N-doping to prepare high-performance supercapacitors.
✓ 已验证
DOI
高影响因子
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2022
·
IF 6.364
Adeel Abbas,Zhuoming Xu,Mohammad Nisar,Delong Li,Fu Li,Zhuanghao Zheng,Guangxing Liang,Ping Fan,Yue-Xing Chen
SnSe is a very strong anisotropic material; sometimes, strong anisotropy is unenviable for producing parts of thermoelectric (TE) devices. In order to study the efficient preparation of high-performance n-type polycrystalline SnSe with weak anisotropy, in this work, we combine mechanical alloying at 450 RPM for 10 h and spark plasma sintering at 773 K under 50 MPa pressure for the preparation of polycrystalline SnSe 0.95- x I x ( x = 0,0.01,0.02,0.03) samples, and investigate the TE properties. The prepared samples show very weak anisotropy. With iodine doping, increased carrier concentration is observed, in agreement with DFT calculations. A peak ZT ≈ 1.02 at 723 K is observed with I-doping of x = 0.02, which is about 225% higher than that of undoped sample with ZT ≈ 0.31 at 723 K in parallel direction, mainly attributed to the enhanced power factor and about 56% reduced thermal conductivity from 0.68 Wm −1 K −1 to 0.30 Wm −1 K −1 . TE properties in both directions are not much different, and the ratios of electrical and thermal conductivities in both directions are very close to unity.
✓ 已验证
DOI
高影响因子
NANO
·
2020
·
IF 1.566
H. Zhang,S. H. Sun,J. C. Liu,F. Hong,Y. Zhu,B. Zhou,Y. M. Hu
Irregular rod-like bismuth sulphochloride (BiSCl) was synthesized by a high efficiency process in which BiCl 3 and Bi 2 S 3 were fully ground and mixed in N 2 atmosphere followed by a sintering at 227 ∘ C for 9 h to achieve crimson BiSCl powder. The products were characterized by X-ray powder diffraction (XRD) and scanning electronic microscopy coupled with energy dispersive X-ray spectroscopy (SEM-EDX). The BiSCl is an n-type semiconductor with a bandgap of 1.9 eV. In the temperature range of 300–500 K, thermal conductivity, electrical conductivity, Seebeck coefficient and thermoelectric figure of merit ZT of the BiSCl were tested and calculated. It is resulted that the BiSCl has a thermal conductivity of 0.45 Wm −1 K −1 at 500 K and a Seebeck coefficient of −579 μVK −1 at 400 K. This work will help inform future in-depth studies on possible applications of BiSCl in the fields of thermoelectricity, optoelectronics and photocatalyticity.
✓ 已验证
DOI
高影响因子
CHINESE PHYSICS LETTERS
·
2024
·
IF 3.5
Longfu Li,Lei Shi,Lingyong Zeng,Kuan Li,Peifeng Yu,Kangwang Wang,Chao Zhang,Rui Chen,Zaichen Xiang,Yunwei Zhang,Huixia Luo
Chemical doping is a critical factor in the development of new superconductors or optimizing the superconducting transition temperature (Tc) of the parent superconducting materials. Herein, a new simple urea approach is developed to synthesize the N-doped α-Mo2C. Benefiting from the simple urea method, a broad superconducting dome is found in the Mo2C1-xNx (0 ≤ x ≤ 0.49) compositions. XRD results show that the structure of α-Mo2C remains unchanged and that there is a variation of lattice parameters with nitrogen doping. Resistivity, magnetic susceptibility, and heat capacity measurement results confirm that the superconducting transition temperature (Tc) was strongly increased from 2.68 K (x = 0) to 7.05 K (x = 0.49). First-principles calculations and our analysis indicate that increasing nitrogen doping leads to a rise in the density of states at the Fermi level and doping-induced phonon softening, which enhances electron-phonon coupling. This results in an increase in Tc and a sharp rise in the upper critical field. Our findings provide a promising strategy for fabricating transition metal carbonitrides and provide a material platform for further study of the superconductivity of transition metal carbides.
✓ 已验证
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2021
·
IF 8.198
Shuang Xu,Xiaopo Niu,Gang Yuan,Zheyuan Wang,Shuaikang Zhu,Xiaoxue Li,Yunxi Han,Rong Zhao,Qingfa Wang
Electrocatalytic synthesis of valuable biofuels and chemicals from biomass-derived acids is a promising approach, but selectively producing deoxygenated hydrocarbons is still a great challenge. In this work, we investigated selective electrochemical decarboxylation of n-octanoic acid to produce hydrocarbons (n-tetradecane, n-heptane, and n-heptene) in a single electrolytic cell at room temperature. Pt nanoparticles with different morphologies (nanospheres, nanoflowers, and nanothorns) and further Pt nanothorns with different plane distributions on carbon fiber paper (CFP) were fabricated by a controllable electrodeposition method. The results proved that the Pt(311) plane has the best selectivity and intrinsic activity for decarboxylation products, especially for Kolbe hydrocarbons. The Pt(110) plane shows a similar intrinsic activity as the Pt(311) planes. High selectivity (75%), yield (35%), and Faraday efficiency (34%) for hydrocarbons were achieved over the Pt nanothorn (Pt-NT), which were approximately 1.6, 2.3, and 3.3 times that of Pt nanoflowers, Pt nanospheres, and Pt/C, respectively. The high electrocatalytic activity of Pt nanothorns was attributed to its high electrochemically active surface area (ECSA) and enhanced intrinsic activity derived from the high level of Pt(311) and Pt(110) planes.
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）