JOURNAL OF LOSS PREVENTION IN THE PROCESS INDUSTRIES
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2022
·
IF 3.916
Yong Pan,Chaoqin Ren,Gan Wang,Yanjun Wang,Xin Zhang,Juncheng Jiang,Chi-Min Shu
Aiming at the green and sustainable energy substitution and supply, biomass valorization has become a potential strategy to face the energy crisis and increasing demand all over the world from long-term perspectives. Among the bio-based chemicals, γ-valerolactone (GVL) production from hydrogenation of levulinic acid (LA) and its esters has attracted great interests due to its wide applications, such as fuel, solvent, and additives. However, the safety evaluation for this hydrogenation reaction has received few attentions. To fill this gap, thermal hazard evaluation for GVL production from LA hydrogenation by using formic acid (FA) as hydrogen donor was first performed. The process conditions were optimized by using orthogonal experimental method for further calorimetry study. Thermal stability of chemicals and thermal risk of reaction process under adiabatic conditions were investigated by applying differential scanning calorimetry and accelerating rate calorimeter Phi-Tec II, respectively. The results revealed that the chemicals were stable in temperature range from 30 to 250 °C except FA due to its evaporation and decomposition with endothermic behaviors. The reaction process under isothermal and adiabatic conditions demonstrates that the decomposition of FA was rapid and followed by the hydrogenation of LA to GVL. Based on kinetic model under adiabatic conditions and risk matrix , the thermal runaway risk was found to be medium, indicating that certain safety measures should be properly designed and taken for loss prevention. This work could benefit the safety design and thermal risk prevention for GVL production by using FA as hydrogen donor.
研究领域:
化学工程
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能源科学
·
安全工程
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产品关联
DOI
高影响因子
Biomass Conversion and Biorefinery
·
2022
·
IF 4.05
Yu Nanxi,Lu Houfang,Yang Wei,Zheng Yuxin,Hu Qiang,Liu Yingying,Wu Kejing,Liang Bin
In the process of converting biomass into high value-added chemicals, transfer hydrogenation as a mild hydrogenation method has attracted more and more attention. The catalysts with hydrogenation sites (nano CuNi alloy) and acid sites (Al oxide) highly dispersed on the surface of a stable support (active carbon) were prepared and the importance of acid sites for the activity of CuNi catalysts in transfer hydrogenation was demonstrated. The catalysts showed promising catalytic activity on the transfer hydrogenation of levulinic acid (LA) to γ-valerolactone (GVL). The CuNi-1Al/AC with 5 wt.% CuNi alloy and 5 wt.% Al got 97.2% GVL yield and 100% LA conversion at 220 ℃ in isopropanol for 2 h. The high activity of the catalyst is attributed to the promoted esterification by the supported acid sites. The Al-modified catalyst also showed activity for esterification reaction in different alcohol hydrogen donors. The catalyst occurs inactive during the cycle due to the shedding of the active components, and the stability of catalyst is effectively improved by a stepwise impregnation. Graphical abstract
研究领域:
催化化学
·
可再生资源化学
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产品关联
DOI
高影响因子
EUROPEAN JOURNAL OF PHARMACOLOGY
·
2025
·
IF 4.7
Qing-qing Fang,Yang-jun Gu,Yong Wang,Zheng-cai Wang,Xiao-ying Lin,Kai Guo,Ze-ming Zhuang,Xin-cao Zhong,Li-yun Zhang,Jian Chen,Wei-qiang Tan
The prevention and treatment of scars has always posed a challenge in the medical field. Researchers have reached the consensus that safe, effective and affordable treatments are needed. Here, by conducting non-targeted metabolomics and RNA sequencing experiments, we revealed that a significant number of metabolites and genes related to glucose and lipid metabolism underwent changes during scar formation, with peroxisome proliferator-activated receptor-γ (PPAR-γ) exerting a profound influence. Considering that rosiglitazone is a selective orally active PPAR-γ receptor agonist, scar models were induced in rats, and rosiglitazone was administered at different dosages. We characterized rosiglitazone as a crucial mediator in a rat scar model in vivo and in vitro in two models of transforming growth factor β1(TGF-β1) stimulated fibroblasts (NIH 3T3 and 3T3 L1). Functionally, activation of PPAR-γ with rosiglitazone effectively impedes fibrosis and mitigates scar formation. Rosiglitazone also inhibits some inflammatory factors, and downregulates triglyceride, lactic acid, glycogen and lactic dehydrogenase levels in rat scars. Conversely, rosiglitazone increases adenosine triphosphate (ATP) production and increases free fatty acid levels and the activity of acetyl-CoA carboxylase, fatty acid synthetase, succinate dehydrogenase. Collectively, these findings shed light on the underlying mechanisms and suggest that the use of rosiglitazone could be a promising therapeutic approach to alleviate fibrosis and reduce scar formation.
研究领域:
医学
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药理学
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分子生物学
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产品关联
DOI
PubMed
高影响因子
Science China-Chemistry
·
2019
·Vol. 62
·期 6
·727-731
·
IF 6.085
Zeng Xuecen,Zhang Xuejing,Liu Shuang,Yang Hao,Tao Zhanliang,Liang Jing
The γ-MnO 2 @CNT catalyst was prepared by in situ solid phase synthesis and first applied into sodium-air batteries (SABs). The initial discharge specific capacity of SABs with γ-MnO 2 @CNT catalyst can reach 8804 mA h g −1 and the overpotential gap is only 140 mV, which is better than the batteries that is catalyzed by α-MnO 2 @CNT and pure CNT. Besides, the batteries also exhibit excellent cycle performance, which can keep relatively stable for 246 cycles at 500 mA g −1 and 140 cycles at 1000 mA g −1 .
研究领域:
材料科学
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电化学
✓ 已验证
DOI
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-12
·
IF 14.7
Ma Xinlong,Yin Haibin,Pu Zhengtian,Zhang Xinyan,Hu Sunpei,Zhou Tao,Gao Weizhe,Luo Laihao,Li Hongliang,Zeng Jie
Acetone serves as an important solvent and building block for the chemical industry, but the current industrial synthesis of acetone is generally accompanied by the energy-intensive and costly cumene process used for phenol production. Here we propose a sustainable route for acetone synthesis via propane wet reforming at a moderate temperature of 350 o C with the use of platinum-tin nanoparticles supported on γ-aluminium oxide (PtSn/γ-Al 2 O 3 ) as catalyst. We achieve an acetone productivity of 858.4 μmol/g with a selectivity of 57.8% among all carbon-based products and 99.3% among all liquid products. Detailed spectroscopic and controlled experiments reveal that the acetone is formed through a tandem catalytic process involving propene and isopropanol as intermediates. We also demonstrate facile ketone synthesis via wet reforming with the use of different alkanes ( e.g ., n-butane, n-pentane, n-hexane, n-heptane, and n-octane) as substrates, proving the wide applicability of this strategy.
研究领域:
化学工程
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催化科学
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能源化工
✓ 已验证
产品关联
DOI
PubMed
高影响因子
GREEN CHEMISTRY
·
2016
·Vol. 18
·期 21
·5900-5914
·
IF 8.506
Shuangtao Yin,Jin Li,Hui Zhang
A series of honeycomb-like hierarchical hollow nanostructured magnetic catalysts, γ-Fe2O3@M3Al-LDH@Au25-x (x represents determined mass of gold in wt%), have been successfully fabricated by modified electrostatic adsorption of water-soluble captopril-capped Au25 nanoclusters (Au25Capt18) on pre-prepared magnetic supports, Fe3O4@M3Al-LDH (M = Ni, Mg, or Cu/Mg (0.5/2.5), LDH: layered double hydroxide) followed by proper calcination. The characterization results show that the low Au-loading samples, γ-Fe2O3@Ni3Al-LDH@Au25-x (x = 0.053, 0.11), show nearly atomically precise Au25 nanoclusters (Au25NCs) (∼1.4 ± 0.3–1.9 ± 0.6 nm) dispersed on the surface of the Ni3Al-LDH shell, while the catalysts, γ-Fe2O3@M3Al-LDH@Au25-x (x ∼ 0.2), display slightly aggregated Au25NCs on the LDH shell with sizes of ∼3.0 ± 1.3, 3.3 ± 1.2, and 4.2 ± 1.5 nm for Ni-, Mg-, and CuMg-based catalysts, respectively, related to varied synergy between Au25NCs and magnetic LDH supports at slightly higher Au loadings. All the γ-Fe2O3@M3Al-LDH@Au25-x catalysts exhibit much higher catalytic activity for the oxidation of 1-phenylethanol under atmospheric O2, without basic additives, in toluene than Fe3O4@Mg3Al-LDH@Au prepared by a traditional deposition–precipitation method. The catalyst, γ-Fe2O3@Ni3Al-LDH@Au25-x, presents even higher alcohol oxidation activity than γ-Fe2O3@Mg3Al-LDH@Au25-0.21 and γ-Fe2O3@Cu0.5Mg2.5Al-LDH@Au25-0.2 and, particularly, γ-Fe2O3@Ni3Al-LDH@Au25-0.053 exhibits the highest activity (TOF: 112 498 h−1) for the aerobic oxidation of 1-phenylethanol under solvent-free conditions and can be applied for a variety of alcohols, this being mainly attributed to its nearly atomically precise Au25NCs and remarkable Au25NCs–LDH–magnetic core three-phase synergistic interaction, along with its abundant Ni-OH sites. Moreover, γ-Fe2O3@Ni3Al-LDH@Au25-0.053 can be easily separated, by simply applying an external magnetic field, and reused for more than ten runs without significant loss of activity, giving the magnetic catalysts long-term stability. These observations make Fe3O4@LDH a universal green platform to support other noble or non-precious metal nanoparticles by using a metal nanocluster precursor method to construct desired metal-loaded ecofriendly catalysts that can be applied in a broad range of heterogeneous catalysis processes.
研究领域:
催化化学
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材料科学
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环境科学
✓ 已验证
DOI
高影响因子
FUEL
·
2022
·
IF 8.035
Yao Liu,Feiyi Chen,Junhua Zhang,Liang He,Lincai Peng
Acid treatment is the key to improve the physicochemical properties of metal-lignocellulosic hybrid, thus contributing to the catalytic performance for catalytic transfer hydrogenation (CTH) of carbonyl compounds to their corresponding alcohols. Herein, a series of organic acids were introduced to assist the design of Zr- Pennisetum sinese hybrid. Comprehensive studies demonstrated the dramatic changes of specific surface and acid/base sites of the prepared hybrid. Remarkably, formic acid-assisted Zr@ PS -FA possessed the largest surface area and enhanced interaction effects between acids (Lewis acid and Brønsted acid) and Lewis base sites, which exhibited excellent catalytic activity for CTH of levulinic acid to γ-valerolactone with a high yield of 95.6% in isopropanol under moderate reaction conditions (180 °C and 1.5 h). Zr@ PS -FA also showed remarkable cycle stability, and it could be consecutively used at least six runs without a significant loss in catalytic activity. More gratifyingly, Zr@ PS -FA displayed a superior universality for CTH of various carbonyl compounds to their corresponding alcohols, demonstrating great potential for upgrading biomass-derived aldehydes/ketones.
研究领域:
化学工程
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生物质能
·
催化科学
✓ 已验证
产品关联
DOI
高影响因子
ECS Journal of Solid State Science and Technology
·
2018
·Vol. 7
·期 12
·R215
·
IF 1.808
Quan Dong,Fengli Yang,Jun Cui,Hong Ming,Fu Du,Jiaqing Peng,Yabin Tian,Shaohua Yang,Xinyu Ye
A series of γ-AlON: Ce3+, Mn2+ phosphors were prepared via a high-temperature solid-state reaction. The phase formation and morphology, photoluminescence excitation and emission spectra, absorption spectra, lifetime, and thermal stability were investigated in detail. The γ-AlON: Ce3+, Mn2+ phosphor showed two emission bands under 285 nm excitation. The first broad band at 400 nm was attributed to Ce3+ ion emission, and the narrow band found at 517 nm was assigned to the Mn2+ ions. The critical distance of energy transfer from Ce3+ to Mn2+ has been calculated according to the concentration quenching method. The mechanism of energy transfer from Ce3+ to Mn2+ was of the resonance type and occurred via a dipole − dipole interaction. After doping Ce3+ in the γ-AlON matrix, the absorption, internal quantum, and external quantum efficiencies of γ-AlON: Ce3+, Mn2+ can be increased to 68.8%, 60.9%, and 41.9%, respectively. Furthermore, γ-AlON: Ce3+, Mn2+ exhibited superior thermal stability, with the emission intensity measured at 150°C maintaining 99% of the maximum emission intensity.
研究领域:
材料科学
·
光学
·
固体物理
✓ 已验证
DOI
高影响因子
Journal of the Taiwan Institute of Chemical Engineers
·
2016
·
IF 2.848
Bolun Sun,Xiang Li,Rui Zhao,Mingying Yin,Zongxin Wang,Ziqiao Jiang,Ce Wang
The hierarchical aminated polyacrylonitrile (PAN)/γ-AlOOH electrospun composite nanofibers were prepared by a combination of electrospinning process, chemical modification and hydrothermal reaction. The obtained membranes were carefully examined by scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS). The hierarchical aminated PAN/γ-AlOOH composite nanofibers were proved to be good adsorbents toward Pb(II), Cu(II) and Cd(II) ions in aqueous solution. The adsorption process of the Pb(II), Cu(II) and Cd(II) ions could be described by Langmuir isotherm model and kinetics were found to follow the pseudo-second-order rate equation. The maximum adsorption capacities of hierarchical aminated PAN/γ-AlOOH electrospun composite nanofibers for Pb(II), Cu(II) and Cd(II) were 180.83 mg/g, 48.68 mg/g and 114.94 mg/g, respectively. The results proved that the synergetic adsorption effect between amine groups and γ-AlOOH crystals contributed to the high adsorption activity of the hierarchical aminated PAN/γ-AlOOH composite nanofibers. The obtained membranes can be potentially applied in heavy metal ions removal from wastewater effluents.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
Polymers
·
2020
·Vol. 12
·期 3
·695
·
IF 3.426
Jie Zheng,Bin Sun,Xiao-Xiong Wang,Ze-Xing Cai,Xin Ning,Saad M. Alshehri,Tansir Ahamad,Xing-Tao Xu,Yusuke Yamauchi,Yun-Ze Long
The exploration of a new family of flexible and high-performance electromagnetic shielding materials is of great significance to the next generation of intelligent electronic products. In this paper, we report a simple magnetic-electrospinning (MES) method for the preparation of a magnetic flexible film, γ-Fe2O3nanoparticle-embedded polymeric nanofibers. By introducing the extra magnetic field force on γ-Fe2O3nanoparticles within composite fibers, the critical voltage for spinning has been reduced, along with decreased fiber diameters. The MES fibers showed increased strength for the magnetic field alignment of the micro magnets, and the attraction between them assisted the increase in fiber strength. The MES fibers show modifications of the magnetic properties and electrical conductivity, thus leading to better electromagnetic shielding performance.
研究领域:
材料科学
·
电子工程
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Jiayu Lin,Wenwen Luo,Zhanwen Wu,Haiyan Leng,Chenghua Sun,Qian Li,Chengzhang Wu
In the present work, three kinds of γ-MnS with different morphologies were prepared by solvothermal method and employed to improve the hydrogen storage properties of MgH 2 . It was found that spherical γ-MnS had the best catalytic activity. The influences of γ-MnS content and milling time on the hydrogen storage performance of MgH 2 were investigated. The initial hydrogen release of MgH 2 -5(γ-MnS)-5 h composite started at 241 ℃, 4.61 wt% of hydrogen was desorbed within 20 min at 270 ℃, and 4.24 wt% of hydrogen was absorbed within 10 min at 150 ℃. The apparent activation energies of hydrogen absorption and desorption of MgH 2 -5(γ-MnS)-5 h composite decreased to 45.1 and 63.6 kJ/mol, respectively. In addition, the composite also exhibited good cycle performance, which could keep stable in 60 cycles. The results of SEM and TEM declared that the catalyst was uniformly distributed on the matrix during the cycling process, and the worm-like morphology of the sample also had a positive effect on the stability of kinetics. XPS analysis of Mn 2p in the samples showed that only characteristic peaks of γ-MnS 2p were observed in the ball-milled samples, but the characteristic peaks of Mn 2p and α-MnS 2p were observed in the first and tenth hydrogenated samples, while only the peaks of Mn 2p were observed in the sixtieth hydrogenated sample. The formation of Mn not only greatly weakened the Mg-H bond, but also led to a slight increase in cycle capacity. Therefore, γ-MnS-doped MgH 2 manifested a good comprehensive hydrogen storage performance.
研究领域:
材料科学
·
能源储存
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Yicheng Yang,Qinan Huang,Lipei Miao,Qihong Zhang,Chongyang Wu,Weike Su,Jingbo Yu
Crocetin (CT), a natural carotenoid dicarboxylic acid known for its high medicinal value, faces challenges such as poor water solubility, low bioavailability and instability, limiting its therapeutic applications. To overcome these challenges, this study introduces a novel Pickering emulsion gel stabilized by naturally sourced chitosan (CS) and γ -polyglutamic acid ( γ -PGA) nanoparticles (CS/ γ -PGA NPs) as a potential transdermal carrier for CT. The CS/ γ -PGA NPs were synthesized using an electrostatic crosslinking method pretreated by mechanical ball-milling, producing uniform and stable nanoparticles. These NPs stabilized a CT-loaded Pickering emulsion gel (CT-PE) with cornmint oil as the oil phase, achieving up to 98.53 % encapsulation efficiency. The CT-PE exhibited enhanced rheological properties, storage stability, sustained and targeted in vitro transdermal release, potent antioxidant activity, and effective antimicrobial effects with no cytotoxicity. Microstructural analysis revealed a dense network of aggregated particles forming a moderately strong gel structure, wherein encapsulated CT enhances emulsion stability through interaction with the gel network. The synergy between CS and γ -PGA facilitated a biocompatible and efficient carrier system, markedly boosting CT's therapeutic effectiveness. These results highlight CT-PE's potential as an effective transdermal carrier for CT, promising for future dermatological treatments and drug delivery systems.
研究领域:
药剂学
·
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）