Biomolecules
·
2023
·Vol. 13
·期 7
·1062
·
IF 5.5
Guohou Miao,Liyu Liang,Wenzhi Li,Chaoyang Ma,Yuqian Pan,Hongling Zhao,Qing Zhang,Yin Xiao,Xuechao Yang
Hydrogels have been widely applied to the fabrication of tissue engineering scaffolds via three-dimensional (3D) bioprinting because of their extracellular matrix-like properties, capacity for living cell encapsulation, and shapeable customization depending on the defect shape. However, the current hydrogel scaffolds show limited regeneration activity, especially in the application of periodontal tissue regeneration. In this study, we attempted to develop a novel multi-component hydrogel that possesses good biological activity, can wrap living cells for 3D bioprinting and can regenerate periodontal soft and hard tissue. The multi-component hydrogel consisted of gelatin methacryloyl (GelMA), sodium alginate (SA) and bioactive glass microsphere (BGM), which was first processed into hydrogel scaffolds by cell-free 3D printing to evaluate its printability and in vitro biological performances. The cell-free 3D-printed scaffolds showed uniform porous structures and good swelling capability. The BGM-loaded scaffold exhibited good biocompatibility, enhanced osteogenic differentiation, apatite formation abilities and desired mechanical strength. The composite hydrogel was further applied as a bio-ink to load with mouse bone marrow mesenchymal stem cells (mBMSCs) and growth factors (BMP2 and PDGF) for the fabrication of a scaffold for periodontal tissue regeneration. The cell wrapped in the hydrogel still maintained good cellular vitality after 3D bioprinting and showed enhanced osteogenic differentiation and soft tissue repair capabilities in BMP2- and PDGF-loaded scaffolds. It was noted that after transplantation of the cell- and growth factor-laden scaffolds in Beagle dog periodontal defects, significant regeneration of gingival tissue, periodontal ligament, and alveolar bone was detected. Importantly, a reconstructed periodontal structure was established in the treatment group eight weeks post-transplantation of the scaffolds containing the cell and growth factors. In conclusion, we developed a bioactive composite bio-ink for the fabrication of scaffolds applicable for the reconstruction and regeneration of periodontal tissue defects.Keywords:3D bioprinting;cell-laden scaffold;composite hydrogel;periodontal regeneration
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2023
·
IF 5.2
Ming Lei,Hua Huang,Junliang Liu,Feng Peng
In the demulsification process of crude oil emulsions, the temperatures of above 60 °C are most commonly required. In this work, a gemini ionic liquid (PGE-TFA) with amphipathy and interfacial activity was prepared by a simple and safe method, which could be used at the temperature of 40 °C for the effective demulsification of crude oil emulsions. The chemical structure and thermostability was investigated by FTIR, 1 HNMR and TGA . The demulsification tests of PGE-TFA showed that it had higher demulsification efficiency (DE) and faster demulsification rate than common commercial demulsifiers. PGE-TFA could be used at a low temperature of 40 °C, a wide pH range and high salinity. The DE reached as high as 95.53 % in water-in-oil emulsions with the concentration of 500 mg/L at 40 °C for 90 min. The temperature of 70 °C could slightly increase the DE and significantly improve the demulsification rate, and the DE of 97.72 % was obtained with the same concentration for 30 min. In addition, the demulsification mechanism was investigated by dynamic interfacial tension, competitive adsorption and zeta potential . The results displayed that PGE-TFA had amphipathy and interfacial activity, which promoted it quickly diffuse to the oil-water interface and displace asphaltenes at the interface. Therefore, an unstable composite film could be formed at the interface and the interfacial tension was lowered, which induced the demulsification of the emulsions.
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Arabian Journal of Chemistry
·
2023
·
IF 6
Ruifeng Liao,Liangliang Shi.,Yi Zhou,Chenyue Jia,Jiangtao Feng,Weinong Zhang,Junbo He
Four novel nonionic 1-alkylaminoglycerol Gemini surfactants, represented by m-s-m ( m = C 8 and C 12 , s = 3 and 4), were synthesized through a two-step reaction in high yields, and confirmed by 1 H NMR, 13 C NMR, and HRMS. The synthesized Gemini surfactants exhibited low CMC (1.41–5.25 mmol/L), excellent surface-tension-reducing ability (25.45–26.83 mN/m), and wetting ability on hydrophobic interface. Gemini surfactants in aqueous solutions were in stable nanoscale dispersion, and exhibited strong and long-lasting foaming ability and emulsifying abilities for benzene/water and triacylglyceride/water systems. Especially, 12 – 4-12 solution displayed excellent tolerance to wide pH range and high salinity. Biological evaluation demonstrated that these Gemini surfactants, except for 8 – 4-8 , showed significant antibacterial activities against Staphylococcus aureus and Escherichia coli at 25 and 50 µg/mL. Hence, these Gemini surfactants have the potential to be used in a varieties of fields as highly efficient agents.
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JOURNAL OF MATERIALS SCIENCE
·
2023
·Vol. 58
·期 15
·6710-6726
·
IF 4.5
Li Shengyu,Mao Weiye,Xia Linying,Wu Xijin,Guo Yingxue,Wang Jingwei,Huang Jie,Xiang Hai,Jin Lu,Fu Huiying,Shou Qiyang
Injectable hydrogels derived from natural extracellular matrices exhibit excellent adhesion to endothelial cells in vitro and are ideal for many biomedical applications. However, their applicability in vivo is limited by the risk of infection or immunogenicity, and the current injectables also suffer from degradation, viscosity, and drug release. In this study, a multifunctional hydrogel scaffold (COB hydrogels) was constructed by incorporating bioactive glass nanoparticles with a Schiff base crosslinking-based hydrogel composed of carboxymethyl chitosan and oxidized cellulose. The incorporation of nanoparticles not only shortened the gelation time of the COB hydrogels, but also enhanced the performance of the hydrogel in terms of function, such as drug loading capacity. The prepared hydrogels also have self-healing ability, injectability, drug loading and sustained release, antibacterial properties and biocompatibility. In addition, given their no cytotoxicity and mild inflammation in vivo, the hydrogel scaffolds will be important for tissue engineering and drug delivery applications.
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CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Hongling Fang,Yi Li,Hua Li,Songwei Zhang,Qi Ding,Wei Yu,Litian Hu
The various forms of friction and wear present in mechanical systems consume a huge amount of the world’s energy sources. Ionic liquids (ILs) have drawn great attention as emerging lubricant materials and currently increasing efforts to drive their commercialization and engineering. Herein, one oil-soluble IL lubricant additive, 2-N-undecylimidazolium bis(2-ethylhexyl) phosphate ([C 11 -IM][DEHP]), has been prepared by “bottom-up” structural design. Compared to the commercially available lubricant additive zinc dialkyl dithiophosphates (ZDDPs) and existing oil-soluble ILs, [C 11 -IM][DEHP] shows significantly superior lubrication performance even at high normal loads (400 N). Its minimum effective concentration (0.1 wt%) is at least tenfold smaller than conventional additives. This extremely low effective concentration is vital to lower the total phosphorus content in the lubricating compounds for environmental protection and cost reduction. Furthermore, the lubrication mechanism was studied in detail by examining the electron transfer at the frictional interface and tribofilm analysis, which further reveal the lubrication nature at electronic scales for ILs.
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JOURNAL OF HAZARDOUS MATERIALS
·
2023
·
IF 13.6
Baolin Chang,Tiannan Cao,Zhizhang Shen,Yipu Zhang,Zhenyu Wang,Ji Li,Jinze Lyu
Obtaining high removal rate of chlorinated volatile organic compounds (CVOCs) and CO 2 selectivity with a low ratio of O 3 /CVOC and energy consumption is challenging. Dodecylamine was used in this study to create active sites on Co 3 O 4 for photo-ozone catalytic mineralization of dichloromethane (DCM). Amine-Co 3 O 4 -450 is a dodecylamine-modified sample with high density of Co 3+ , Co 2+ , and hydroxyl due to its nanosheet structure and exposed (112) facets. The optimized surface significantly enhanced the cleavage of the C–Cl bond at low temperatures. Photocatalysis primarily participated in the oxidation of intermediates following DCM dichlorination and significantly improved CO 2 selectivity. The respective DCM removal rate and mineralization efficiency of Amine-Co 3 O 4 -450 with an O 3 /DCM molar ratio of 1.27 and one-sun irradiation were 14.9 and 15.0 times higher than the sum of those in the presence of light irradiation or O 3 alone. This finding indicated that a strong synergistic effect exists between O 3 and light.
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CATALYSIS SURVEYS FROM ASIA
·
2023
·Vol. 27
·期 3
·207-216
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IF 3
Li Shuying,Huang Bin,Jin Changzi,Wang Rui,Jiang Heng,Yang Guang-Sheng,Huang Shengjun
The conversion of ethanol and acetaldehyde to 1,3-butadiene has been an emerging process to produce key chemicals. The preparation of highly efficient catalysts and the understanding of reaction mechanism are current research priority. Herein, mesoporous silica framework confining zirconia (Zr-HMS) was prepared and act as catalyst for 1,3-butadiene production from ethanol and acetaldehyde. The prepared catalysts were characterized by Low-angle X-ray powder diffraction, transmission electron microscopy, N 2 physical adsorption-desorption, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy and UV–vis spectra. It has been shown that the Zr-HMS exhibits similar textural properties to supported catalyst (ZrO 2 /HMS). However, regardless of their comparable activities, higher 1,3-butadiene selectivity is obtained over Zr–HMS, which can be due to the different active zirconia species in two catalysts. Mesoporous framework confining character of Zr-HMS can achieve uniformly dispersed zirconia species. Further investigation toward the reaction process has presented new viewpoints for formation and consumption of some typical intermediates and byproducts, which will help to understand the reaction mechanism and construct efficient catalysts for conversion of ethanol and acetaldehyde to 1,3-butadiene.
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Inorganic Chemistry Frontiers
·
2019
·Vol. 6
·期 6
·1382-1387
·
IF 5.934
Yuanmeng Zhao,Guixiang Mao,Chaozhang Huang,Ping Cai,Gongzhen Cheng,Wei Luo
Searching for highly efficient and stable electrocatalysts applied for the hydrogen evolution reaction (HER) in an alkaline solution is highly desirable, but still remains a challenge due to the sluggish water dissociation kinetics. Herein, in this work, ultrafine Ru nanoparticle (NP) decorated WSe2 nanosheets have been successfully prepared by a colloidal synthetic approach. Benefiting from the interfacial synergy effect between WSe2 nanosheets and Ru NPs, the rate-determining water dissociation step for the alkaline HER and the subsequent hydrogen generation step are speeded up. As expected, the resultant Ru–WSe2 hybrid with 1.93 wt% Ru loading exhibits excellent catalytic performance for HER media, with an overpotential of 87 mV to achieve a current density of 10 mA cm−2, and superior long-term stability.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2019
·
IF 3.131
Tao Yan,Taiheng Zhang,Guoqing Zhao,Chongyang Zhang,Caifeng Li,Feipeng Jiao
More and more attention has been paid to materials with special wettability for the potential application in oil/water separation and oil-spill treatment. In this work, we presented a simple, efficient, and environmentally friendly method to develop a magnetic textile that could achieve switchable wettability by changing the pH value of the surface. The textile was fabricated by a mixture of Fe 3 O 4 nanoparticles and dodecylamine (DDA)-modified TiO 2 with high permeate flux, high separation efficiency and good stability. The Fe 3 O 4 /DDA-TiO 2 textile showed its superhydrophobicity and superoleophilicity for neutral water (pH = 7), while the textile became superhydrophilic and underwater superoleophobic for acidic water (pH = 2).The as-prepared textile was investigated using eight different density oil/water mixtures. The results showed that the as-prepared textile possessed excellent separation efficiency (>99%) and high oil flux of about 9400–13,000 L h −1 m -2 , water flux of about 6400–6700 L h −1 m -2 and good reusability. Meanwhile, the textile can maintain superhydrophobic under high temperature (˜170 °C), which significantly indicated its practical application in harsh environment. Because of its magnetism, the textile can be recovered and removed by magnets. We believe that this work may provide a number of potential application, such as microfluidic device, oil recovery and sewage purification.
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ADVANCED FUNCTIONAL MATERIALS
·
2019
·Vol. 29
·期 24
·1900991
·
IF 15.621
Keqiang Chen,Qiaohui Zhong,Wen Chen,Binghua Sang,Yingwei Wang,Tingqiang Yang,Yueli Liu,Yupeng Zhang,Han Zhang
Cubic phase CsPbI 3 (α-CsPbI 3 ) perovskite quantum dots (QDs) have received extensive attention due to their all-inorganic composition and suitable band gap (1.73 eV). However, α-CsPbI 3 QDs might convert to δ-CsPbI 3 (orthorhombic phase with indirect band gap of 2.82 eV) due to easy loss of surface ligands. In addition, commonly used long-chain ligands (oleic acid, OA, and oleylamine, OLA) hinder efficient charge transport in optoelectronic devices. In order to relieve these drawbacks, OA, OLA, octanoic acid, and octylamine are used as capping ligands for synthesizing high-quality α-CsPbI 3 QDs. The results indicate that these QDs exhibit excellent optical properties and long-term stability compared to QDs capped only with OA and OLA. Moreover, QDs with shorter ligands exhibit an enhanced charge transport rate, which improves the power conversion efficiency of photovoltaic devices from 7.76% to 11.87%.
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JOURNAL OF SURFACTANTS AND DETERGENTS
·
2019
·Vol. 22
·期 3
·411-419
·
IF 1.672
Ruijuan Wang,Dong Wang,Zhigang Yin,Xuzhao Yang,Quan Liu
The carboxylic acid-type Gemini surfactant (CGS12) was synthesized, and its micellization in aqueous solution at different pH values at 25.0 °C was investigated. The results show that the critical micelle concentration (CMC) of CGS12 at different pH values is only 10 −6 order of magnitude, and the pH has little effect on the CMC. Moreover, the interaction of CGS12 with amino acid surfactant of sodium N-lauroyl sarcosinate (SLS) at 25.0 °C and pH 7.0 was investigated using surface tension, dynamic light scattering (DLS), cryogenic transmission electron microscopy (Cryo-TEM), and Ross–Miles foam measurements. The CGS12/SLS mixture shows a low CMC, and as a whole the CMC value becomes smaller with increasing molar fraction of CGS12 (X CGS12 ). Under different X CGS12 , the mixtures form soluble aggregates with different hydration radii ( R h ). Moreover, the mixture aggregates are mainly in the form of vesicles. The foaming height of CGS12 is worse than that of SLS, but the CGS12/SLS mixture has good foaming stability. This work reveals that the surfactant mixture has good surface activity and good foam stability.
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Nanoscale
·
2018
·Vol. 11
·期 3
·1423-1436
·
IF 7.233
Rong Chen,Qun Chen,Huan Qin,Da Xing
Drug delivery to a tumor site with an insufficient microvascular network remains a challenge due to the size preference for transport in terms of circulation and distribution. In this work, an integrated nano-therapeutic parcel disintegrable by a photoacoustic shockwave was developed. Nano-therapeutic particles with red absorbance are packaged into a larger parcel to generate a longer circulation half-life and improved accumulation in tumor tissue. Pulse-laser irradiation is absorbed by the nanoparticles and it generates a photoacoustic shockwave. This triggers a liquid–gas phase transition of the nano-parcel, leading to the high-efficiency release of smaller nanoparticles, thus achieving excellent therapeutic diffusion with improved uniformity. This results in a highly effective therapeutic effect, as demonstrated with both in vitro and in vivo tumor models. Compared to previously reported work, this approach has the distinctive advantage of precisely controllable therapeutic release that is independent of the physiological environment in the tumor and it is less limited than a UV-based release mechanism. In addition, the concept of photoacoustic shockwave-based nanoparticle release can be extended over a wide wavelength range, including microwaves, to match specific needs and achieve optimal therapeutic depth. The results demonstrate that the proposed strategy holds great potential for improved tumor therapy efficacy.
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