JOURNAL OF MEMBRANE SCIENCE
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2026
·
IF 8.8
Bo Peng,Hongwei Lu,Shuai Gu,Juntao Tang,Chunyue Pan,Guipeng Yu
Highly selective nanofiltration membranes are ideal candidates for efficient water purification. However, achieving superior selectivity without sacrificing water permeance remains a considerable challenge. Drawing inspiration from the structural features of squid skin, a biomimetic strategy was devised that integrates cyclohexane-induced swelling with surface grafting employing hydrophilicity-tuned monomers to enhance the performance of polyamide thin-film composite membranes (PA-TFC). Remarkably, grafting with aminoacetaldehyde dimethyl acetal (ADA), the most hydrophilic monomer, effectively mimicked the natural hydration layer, thereby enabling rapid and unhindered water transport. Consequently, the resulting ADA-modified nanofiltration (ADA-NF) membrane exhibits an ultrahigh NaCl/Na 2 SO 4 separation factor of 263.2, while doubling the water permeance to 15.9 L m −2 h −1 bar −1 . Additionally, large-scale roll-to-roll production of this type of biomimetic nanofiltration membrane has been successfully demonstrated. The ADA-NF membrane exhibits significantly enhanced anti-fouling properties due to its tailored surface charges, while maintaining stable performance. The ADA-NF membrane offers a practical route to address the permeance-selectivity trade-off, while its fabrication strategy maintains a high degree of compatibility with existing industrial production lines. This unique biomimetic strategy provides valuable insights into the rational design of NF membranes for highly selective separation.
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ACS Omega
·
2026
·
IF 5.2
Kermue Vasco Jarnda,Heng Dai,Huiting Hu,Yuan Tian,Richmond Anaman,Pian Wu,Ping Ding
Recent advancements in microfluidic paper-based analytical devices (μPADs) have demonstrated their significant potential for point-of-care testing (POCT), particularly in low-resource settings. These devices are especially promising for monitoring glucose levels in patients with diabetes, offering a cost-effective and portable solution. However, one of the primary challenges hindering the widespread adoption of smartphone-coupled μPADs has been their sensitivity to varying ambient lighting conditions, which can interfere with accurate colorimetric detection. To address this issue, researchers have introduced a novel approach involving a metal–organic framework (MOF), specifically Co-TCPP (Fe) [cobalt Fe(III) meso-tetra(4-carboxyphenyl) porphyrin chloride], synthesized using a straightforward method. Co-TCPP (Fe) exhibits remarkable peroxidase-like activity when exposed to hydrogen peroxide (H2O2), enabling it to interact effectively with classic chromogenic substrates and thus improving the colorimetric reaction crucial for accurate glucose detection. In this study, the team developed paper-based μPADs that incorporate the Co-TCPP (Fe) MOF, allowing it to accurately detect glucose levels across a wide concentration range. The limit of detection (LOD) achieved was 5.3 μM, with a linear detection range from 5 to 750 μM. This innovation addresses previous concerns regarding the impact of environmental lighting fluctuations and varying shooting angles, ensuring the reliability of glucose measurements under uncontrolled conditions. By integrating this algorithm into a smartphone-coupled μPAD system, the researchers have created a portable, high-resolution platform that delivers dependable results, even in challenging and fluctuating environments. This breakthrough marks a significant step toward enhancing the practicality and accessibility of glucose monitoring in resource-constrained settings, providing a valuable tool for both clinical and everyday use.
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ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Qiao Wan,Yajun Li,Yahong Su,Wenqing Jia,Jiang Zhu,Qiang Yu,Zhen Chen,Lingli Lei,Yuanyuan Zhang
This study aims to develop a high-performance, low-cost non-enzymatic electrochemical sensing materials for glucose detection, addressing the limitations of existing technologies. A three-dimensional porous hierarchical layered-nanoflower heterostructured CuCoP/MXene composite was synthesized through in situ growth of CuCo-MOF nanoflowers on Ti 3 C 2 -MXene via a one-step hydrothermal method, followed by oxidation and phosphidation treatments. This unique architecture significantly increases the specific reactive surface area, exposes abundant active sites, and provides sufficient interfacial regions for glucose oxidation. The synergistic effect between copper (Cu) and cobalt (Co) further enhances the electrocatalytic performance. Meanwhile, MXene serves as a conductive scaffold that not only facilitates electron transfer but also promotes the diffusion and adsorption of glucose molecules, owing to its excellent conductivity and continuous interlayer channels. The fabricated sensor exhibits an extensive linear detection range (0.5-6000 μM), high sensitivity (1408.49 μA mM -1 ·cm -2 ), a low detection limit (0.14 μM, S/N=3), along with excellent selectivity, reproducibility, and stability, together with a swift response time (3 s). Moreover, the sensor has been successfully applied to the accurate detection of glucosein samples of serum, showing high reliability and promising practical value.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Zhen Zhang,Xiaojian Tian,Yuxiao Sun,Dandan Han,Bang Gu,Dan Wu,Armin Rezayan,Xian Wu,Jingpeng Zhao,Jianshe Wang,Tianliang Lu,Renfeng Nie,Xiaoqin Si,Chunbao Xu,Yongsheng Zhang
Vanadium-based catalysts are widely used in the oxidation of carbohydrates to produce formic acid (FA), a promising liquid organic hydrogen carrier, but still suffers from low yield due to the formation of CO 2 . This study found that the spatially isolated VO x on active carbon (AC) can significantly increase FA yield from 43.5 to 72.9% in glucose oxidation compared with free VO x . Two specific roles of AC were revealed. Firstly, the oxygenated functional groups, high surface area and abundant microporous of AC, play a crucial role in the atomic dispersion of VO x , resulting in a heterogeneous, single-site VO x -AC catalyst. The isolated VO x site favors the oxidative C C bond cleavage in glucose via a stepwise α-cleavage pathway, thus improving FA selectivity. Secondly, the conductive AC acts as an electron buffer, which accelerates the catalytic redox cycle between V 5+ and V 4+ of the isolated VO x sites, thus increasing the reaction activity. The prepared single-site VO x -AC catalyst is reusable and can generate a concentrated FA solution (4.7 wt%) by simple filtration of the solid catalyst. This work presents a simple method for the production of H 2 energy carrier from biomass and provides a fundamental basis for designing efficient catalytic systems for aqueous-phase oxidation reactions.
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MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Hao Sun,Weiyun Guo,Yaru Han,Zhifei Gou,Yanmin Liang,Jie Dan,Yi Kang,Jianlong Wang,Wentao Zhang
Drawing on the structure of the natural horseradish peroxidase (HRP) active site, in this study, food-borne Melanoidin and Fe 3+ were used to construct a peroxide mimic enzyme, which possessed excellent peroxidase (POD)-like activity with the Km values of 0.088 mM and 0.358 mM toward 3,3′,5,5′-tetramethylbenzidine (TMB) and hydrogen peroxide (H 2 O 2 ), respectively. Given the good POD-like activity of Melanoidin/Fe 3+ , a convenient, selective, and sensitive method for the determination of ascorbic acid (AA) was defined. The method covered the 10–100 μM AA concentration range with a 1.19 μM detection limit. With favorable anti-interference and strong stability, Melanoidin/Fe 3+ was successfully applied to the determination of AA in foods and medicines. The high activity of Melanoidin/Fe 3+ provides a new strategy for designing high-performance nanozymes, which has great potential in exogenous dietary and healthcare applications.
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Chunhua Li,Xiao Xu,Fuli Wang,Yue Zhao,Yubo Shi,Xin Zhao,Jue Liu
It is significant to develop low-cost, sensitive, and portable sensing platform for point-of-care testing of ascorbic acid (AA) in food quality evaluation. Herein, a smart point-of-care (SPOC) sensor, consisting of fluorescent paper chip, 3D printed-accessories and smartphone, was developed for ultrasensitive and visual quantitative detection of AA. Fluorescent paper chip was made through printing silicon doped carbon dots (SiCDs)-Fe 3+ as “ink” onto filter paper, in which SiCDs emitting strong fluorescence signal quenched by Fe 3+ , and then recovered by AA owing to releasing –NH 2 /–OH and introducing defects on SiCDs. The smartphone with an application named “ AA-Tester ” was established to analyze AA and exhibited high sensitivity with low detection limits of 18.12 nmol/L. HPLC method was used to verify the SPOC sensor and obtained satisfactory accuracy with relative standard deviations of 0.79–2.31 %. The portable sensing platform integrated fluorescence sensor with smartphone-device will be favorable for ultrasensitive and on-the-spot detection of AA.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2022
·Vol. 23
·期 18
·10743
·
IF 6.208
Teng Wang,Xi Hu,Yujun Yang,Qing Wu,Chengdian He,Xiong He,Zhenyu Wang,Xiang Mao
Metal-based enzyme mimics are considered to be acceptable agents in terms of their biomedical and biological properties; among them, iron oxides (Fe3O4) are treated as basement in fabricating heterogeneous composites through variable valency integrations. In this work, we have established a facile approach for constructing Fe3O4@Ag composite through assembling Fe3O4and Ag together via polyethyleneimine ethylenediamine (PEI) linkages. The obtained Fe3O4@PEI@Ag structure conveys several hundred nanometers (~150 nm). The absorption peak at 652 nm is utilized for confirming the peroxidase-like activity of Fe3O4@PEI@Ag structure by catalyzing 3,3′,5,5′-tetramethylbenzidine (TMB) in the presence of H2O2. The Michaelis–Menten parameters (Km) of 1.192 mM and 0.302 mM show the higher catalytic activity and strong affinity toward H2O2and TMB, respectively. The maximum velocity (Vmax) value of 1.299 × 10−7M∙s−1and 1.163 × 10−7M∙s−1confirm the efficiency of Fe3O4@PEI@Ag structure. The biocompatibility illustrates almost 100% cell viability. Being treated as one simple colorimetric sensor, it shows relative selectivity and sensitivity toward the detection of glucose based on glucose oxidase. By using indocyanine green (ICG) molecule as an additional factor, a remarkable temperature elevation is observed in Fe3O4@PEI@Ag@ICG with increments of 21.6 °C, and the absorption peak is nearby 870 nm. This implies that the multifunctional Fe3O4@PEI@Ag structure could be an alternative substrate for formatting acceptable agents in biomedicine and biotechnology with enzymatic and photothermal properties.Keywords:Fe3O4@PEI@Ag;assembling process;enzymatic;catalytic performance;photothermal property
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JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
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2022
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IF 5.141
Xiufeng Wang,Yunyun Zhang,Yao Jin,Siqi Wang,Zhiqing Zhang,Ting Zhou,Guodong Zhang,Fang Wang
Quantum dots (QDs) are excellent fluorescent indicators for chemical and biological analysis. In this paper, an Off-Off fluorescence sensor based on ZnS quantum dots was designed. It was found that Co 2+ can quench the fluorescence of ZnS QDs, moreover glutathione (GSH) can further quench the fluorescence. Therefore, this method can be used for indirect detection of GSH. However, if change Co 2+ into other metal ions, the system cannot be used to detect GSH indirectly. For direct detection GSH, that is adding GSH without Co 2+ , the fluorescence intensity changes little, while only amino acid or monosaccharide has no effect. When indirect detection of GSH based on this Off-Off fluorescent probe, the fluorescence quenching was linearly related to the concentration range of 1–300 μM GSH, and the detection limit could reach 0.48 μM, which can rival most Off-On and On-Off fluorescent probe. The relative standard deviation for parallel measurement of 300 μmol·L -1 GSH solution (for n = 10) was 1.43 %.
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Xiuying Liu,Fei Xia,Shaoen Zhang,Yuanyuan Cheng,Ling Fan,Si Kang,Xue Gao,Xiaofei Sun,Jianrong Li,Xuepeng Li,Lijie Zhu
Nitrofurans such as furaltadone and nitrofurantoin are a type of synthetic broad-spectrum antibiotics. Various fluorescent nanomaterials have been used as labeling materials in immunochromatographic assays (ICAs) for nitrofurans detection. However, previous fluorescent nanomaterials can undergo aggregation-caused quenching, leading to a decrease in the detection sensitivity. In this study, we developed a multiplex immunochromatographic assay (mICA) based on dual-color aggregation-induced emission nanoparticles (AIENPs) as signal labels for the simultaneous detection of 3-amino-5-morpholino-methyl-1,3-oxazolidinone (AMOZ) and 1-aminohydantoin (AHD), which were the metabolites of furaltadone and nitrofurantoin, respectively. Under optimal conditions, the cut-off values of the mICA for derivatized AMOZ (2-NP-AMOZ) and AHD (2-NP-AHD) reached up to 3 and 5 ng/mL, respectively. These values are at least 166-and 200-fold higher than those of the commercial gold nanoparticles (GNPs)-based test strip, respectively. Furthermore, the test strip was successfully applied to the samples, with acceptable recoveries in the range of 83.0–98.2%.
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Chunling Chen,Yijun Pan,Yifei Niu,Dengfeng Peng,Wenjing Huang,Wangyang Shen,Weiping Jin,Qingrong Huang
Oil body (OB) is the lipid-storage organelle in oilseed, and its stability is crucial for oilseed processing. Herein, effects of roasting and boiling on the structure, stability, and in vitro lipid digestion of Camellia OB were studied. The interfacial structure and physical stability of the extracted OB were investigated by electrophoresis, confocal-Raman spectroscopy, zeta-potential, and surface hydrophobicity, etc . Boiling caused protein loss on the OB surfaces, forming a stable phospholipid interface, which resulted in coalescence of the droplets (d > 100 μm) and negative ζ-potential (-3 ∼ -8 mV) values at a pH of 2.0. However, roasting partially denatured the proteins in the seeds, which were adsorbed on the OB surfaces. The random coil structure of interfacial protein increased to ∼20 % after thermal treatment. Besides, heating decreased the surface hydrophobicity of OB and improved lipid digestion. After boiling 60 min, the extent of lipolysis increased from 41.7 % (raw) to 57.4 %.
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ELECTROANALYSIS
·
2023
·Vol. 35
·期 7
·e202200519
·
IF 3
Man Zheng,Bohan Cao,Jiaxian Liu,Kun Shi,Yufan Zhang,Huan Wang
In this study, a simple method was designed to prepare ordered mesoporous carbons embedded with molybdenum without any extreme conditions. We prepared three different ordered molybdenum carbide materials with mesoporous structures to explore the influence of the structure of molybdenum-based materials on the HER catalytic efficiency. The ordered mesoporous molybdenum carbide catalysts (CMK-3-MoCx, fCMK-3-MoCx, CMK-8-MoCx) were characterized by SEM, TEM, XRD, nitrogen adsorption-desorption and XPS. The HER is catalyzed efficiently on the three electrocatalysts, fCMK-3-MoCx shows the best HER electro-catalytic performance with a small onset potential of −0.06 V vs. RHE, a low tafel slope of 66 mV dec −1 and a small over-potential value of 89 mV at 10 mA cm −2 . This excellent performance on HER is due to its high specific surface area and highly ordered mesoporous structure that resulted in excellent proton transport efficiency and high electron transfer rate. Our results provide a new research direction for the application of flat ordered mesoporous structures in catalysis.
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Food & Function
·
2023
·Vol. 14
·期 4
·1897-1908
·
IF 6.1
Yuan Yuan,Shun Zhong,Zeyuan Deng,Guangyan Li,Hongyan Li
In this study, the effects of particle size on the microstructure, nutrient components and antioxidant activities of bee pollen were evaluated. Moreover, the in vitro simulated digestion model was used to explore whether there was a size effect on the release behavior of phenolic compounds from the bee pollen matrix. Results showed that the greater the damage degree of the bee pollen wall, the smaller the bee pollen particle became. The decrease in the bee pollen particle size promoted the release and extractability of sugar, protein, phenolics and flavonoids, and improved their antioxidant activities. In addition, during simulated digestion, the dissolution of total phenolics and flavonoids, as well as the antioxidant activities of bee pollen, increased with the decrease in the particle size. Results showed that minimizing the particle size of bee pollen was not always beneficial for bioaccessible phenolic compounds because their content and bioavailability decreased when the particle size became smaller than 200 μm.
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