Journal of CO2 Utilization
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2021
·
IF 7.132
Qin Ying,Han Chen,Peijing Shao,Xiaowei Zhou,Xiaojia He,Jiexu Ye,Shihan Zhang,Jianmeng Chen,Lidong Wang
Tertiary amine-based absorption process possesses high absorption capacity and low heat duty for CO 2 capture. However, its slow CO 2 absorption rate retards its industrial application. This work developed a core-shell magnetic ZIF-8@Fe 3 O 4 -carbonic anhydrase composite to promote CO 2 absorption into tertiary amine, e.g., diethanolamine (MDEA) due to its easy recovery from the solution. The catalytic performance of CA@ZIF-8@Fe 3 O 4 that had three particle sizes were investigated. Experimental results revealed that the obtained CA@ZIF-8@Fe 3 O 4 can achieve the relative activity as high as 95.2 % compared with the free counterparts. Large particle size of ZIF-8@Fe 3 O 4 was beneficial to activity but adverse to loading. Magnetic analysis shows that the developed CA@ZIF-8@Fe 3 O 4 possessed remarkable magnetic response which made recycling more convenient.
研究领域:
化学工程
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环境科学
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生物技术
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高影响因子
Polymers
·
2021
·Vol. 13
·期 9
·1515
·
IF 4.329
Xiukun Xue,Yanjuan Wu,Xiao Xu,Ben Xu,Zhaowei Chen,Tianduo Li
Polymeric prodrugs, synthesized by conjugating chemotherapeutic agents to functional polymers, have been extensively investigated and employed for safer and more efficacious cancer therapy. By rational design, a pH and reduction dual-sensitive dextran-di-drugs conjugate (oDex-g-Pt+DOX) was synthesized by the covalent conjugation of Pt (IV) prodrug and doxorubicin (DOX) to an oxidized dextran (oDex). Pt (IV) prodrug and DOX were linked by the versatile efficient esterification reactions and Schiff base reaction, respectively. oDex-g-Pt+DOX could self-assemble into nanoparticles with an average diameter at around 180 nm. The acidic and reductive (GSH) environment induced degradation and drug release behavior of the resulting nanoparticles (oDex-g-Pt+DOX NPs) were systematically investigated by optical experiment, DLS analysis, TEM measurement, and in vitro drugs release experiment. Effective cellular uptake of the oDex-g-Pt+DOX NPs was identified by the human cervical carcinoma HeLa cells via confocal laser scanning microscopy. Furthermore, oDex-g-Pt+DOX NPs displayed a comparable antiproliferative activity than the simple combination of free cisplatin and DOX (Cis+DOX) as the extension of time. More importantly, oDex-g-Pt+DOX NPs exhibited remarkable reversal ability of tumor resistance compared to the cisplatin in cisplatin-resistant lung carcinoma A549 cells. Take advantage of the acidic and reductive microenvironment of tumors, this smart polymer-dual-drugs conjugate could serve as a promising and effective nanomedicine for combination chemotherapy.Keywords:polymeric prodrug;dual-sensitive;combination chemotherapy;drug conjugation;dextran
研究领域:
肿瘤学
·
药剂学
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DOI
PubMed
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
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2021
·Vol. 101
·期 15
·6355-6367
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IF 3.639
Shiyuan Luo,Abdullah Saadi,Kai Fu,Maierhaba Taxipalati,Lingli Deng
BACKGROUND In recent years, there has been considerable interest in the use of biopolymer electrospun nanofibers for various food applications due to the biocompatibility, biodegradability, and high loading capacity. Herein, we fabricated and characterized novel hybrid electrospun fibers from dextran (50%, w/v ) and zein (0–30%, w/v ) solutions, and the effects of various zein concentrations on the properties of the hybrid electrospun fibers were investigated. RESULTS When zein was added at low concentrations (5% and 10%), dextran and zein showed poor miscibility, as reflected by significantly decreased viscosity of the solutions, and the poor mechanical properties of the derived fiber membranes. When zein was added at medium concentrations (15–25%), hydrogen bonds were formed between dextran and zein molecules, as indicated by the red shift of Fourier-transform infrared bands and β-sheet to α-helix structural transformations. The fiber membranes electrospun from a solution with 25% zein showed the most hydrophobic surface, with a water contact angle of 116.9°. The homogenous dispersion of dextran and zein resulted in improved mechanical properties for fibers electrospun from a solution with 30% zein. Curcumin encapsulating dextran/zein electrospun fibers exhibited effective radical scavenging activity and ferric reducing power, along with the desired controlled release behavior for curcumin delivery. CONCLUSION Food grade dextran/zein hybrid electrospun fibers demonstrated tunable properties, and appear to be promising as delivery systems for bioactive and edible antimicrobial food packaging. © 2021 Society of Chemical Industry.
研究领域:
食品科学
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材料科学
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DOI
PubMed
高影响因子
Polymers
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2019
·Vol. 11
·期 5
·881
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IF 3.164
Lijun Gao,Xianggen Chen,Xiangjun Liang,Xiuzhi Guo,Xianling Huang,Caifen Chen,Xiaodan Wan,Ruyu Deng,Qifeng Wu,Lingyun Wang,Jiuying Feng
The thermoplastic poly(propylene carbonate) (PPC) containing cross-linked networks was one-pot synthesized by copolymerization of carbon dioxide, propylene oxide (PO), maleic anhydride (MA), and furfuryl glycidyl ether (FGE). The copolymers were characterized by Fourier transform infrared spectroscopy (FT-IR), gel permeation chromatography (GPC), differential scanning calorimetry (DSC), and thermogravimetric analysis (TGA) measurements. The thermal and dimensional stability of the copolymers were improved. When the MA and FGE load increased from 1 mol% to 4 mol% of PO, the copolymers contained the gel contents of 11.0%–26.1% and their yields were about double that of the PPC. The 5% weight-loss degradation temperatures (Td,-5%) and the maximum weight-loss degradation temperatures (Td,max) increased from 149.7–271.3 °C and from 282.6–288.6 °C, respectively, corresponding to 217.1 °C and 239.0 °C of PPC. Additionally, the hot-set elongation tests showed that the copolymers exhibited elasticity and dimensional stability with the minimum permanent deformation of 6.5% which was far less than that of PPC of 157.2%, while the tensile strengths were a little lower than that of PPC because of the following two conflicting factors, cross-links and flexibility of the units formed by the introduced third monomers, MA and FGE. In brief, we provide a novel method of one-pot synthesis of PPC containing cross-linked networks. According to this idea, the properties would be more extensively regulated by changing the cross-linkable monomers.Keywords:poly(propylene carbonate);networks;copolymerization;modification
研究领域:
材料科学
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化学工程
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DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2020
·Vol. 138
·期 17
·50315
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IF 2.52
Yitian Qin,Zhao Zhang,Guodong Kang,Zhihao Zhu,Haijun Yu,Yiming Cao
Acyl chloride monomers have been serving as the dominant acylation reagent for preparing thin-film composite (TFC) nanofiltration (NF) membranes over the past few decades. Herein, a novel acylation reagent (trimellitic anhydride, TMA) was exploited in conjunction with trimesoyl chloride (TMC) to undergo interfacial polymerization with piperazine (PIP) on the polysulfone substrate membranes. The introduction of TMA enabled the deeper diffusion of PIP monomers into the organic phase, resulting in the creation of novel circular-shaped protuberances on the top surface of the polyamide layer and the significant increase in the effective membrane area. Besides, abundant in-situ carboxylic groups were generated in the polyamide layer, conducive to both the surface hydrophilicity and negative charge density. Consequently, with an addition of 0.03 wt% TMA, pure water flux reached up to 15.3 L m −2 hour −1 bar −1 , almost 2.2 times that of the pristine membrane, and high rejection of Na 2 SO 4 (97.3%) was maintained, evincing the superior desalination performance of the TMA-modified membranes. The interaction mechanism between TMA, TMC, and PIP was described in detail. Furthermore, the TMA-modified membranes exhibited a stable separation performance over the long-running process.
研究领域:
材料科学
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环境工程
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DOI
高影响因子
CARBOHYDRATE POLYMERS
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2014
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IF 3.916
Yu Zhao,Xinge Zhang,Yanan Wang,Zhongming Wu,Jinxia An,Zhentan Lu,Lin Mei,Chaoxing Li
Many synthetic hydrogels for drug delivery have been based on polyethylene glycol which is non-natural, non-biodegradable and only terminal-functionalizable. The polysaccharides dextran and chitosan not only are highly hydrophilic, biodegradable and pendant-functionalizable, but also more closely mimic the nature extracellular matrix glycosaminoglycans. Here, a biomimetic hydrogel based on chitosan and dextran was synthesized by the Michael addition reaction. The hydrogels have good swelling and cytocompatibility against NIH3T3. Moreover, vancomycin-loaded hydrogels were formed in situ, and could kill both Gram-positive bacteria and Gram-negative bacteria, indicating that the hydrogel as a wound dressing could provide protection against bacterial infection. Notably, the drug release was controlled via modifying the compositions. Therefore, the biomimetic polysaccharide hydrogels as a promising carrier have potential application for wound healing.
研究领域:
生物材料学
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药物递送系统
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感染控制
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DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
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2017
·Vol. 52
·期 17
·10431-10438
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IF 2.599
Chi Kailin,Li Qian,Meng Xianwei,Liu Li,Yang Haibin
Cadmium telluride (CdTe) micro-/nanoscale structures, including micropillars, micro-/nanorods and microflowers arrays, were successfully and controllably synthesized by electrodeposition on nickel substrates. Various characterization techniques, such as X-ray diffraction, scanning electron microscopy (SEM), energy-dispersive spectroscopy, selected area electron diffraction and Raman spectroscopy, were used to characterize the structures and properties of the as-prepared films. The structural analysis revealed that the as-synthesized CdTe films deposited in different concentrations of sulfuric acid system had cubic phases and possessed a polycrystalline structure with preferred orientations along the [111] direction. The results of SEM showed that the sulfuric acid concentrations had a significant effect on the morphology evolution from micropillar arrays to microflower arrays, and a possible formation mechanism was proposed. In addition, according to the results of the optical and photoelectrochemical performances in the visible-light region, the as-synthesized films have considerable potential to be applied as absorber materials in substrate configuration solar cells.
研究领域:
材料科学
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纳米技术
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光电化学
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DOI
高影响因子
MATERIALS LETTERS
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2014
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IF 2.269
Linhua Zhu,Xianghui Wang,Luyong Wu,Yi Luo,Yuqing Zhu,Qiang Lin,Zaifeng Shi
Poly(propylene carbonate pyromellitic dianhydride) (PPCPD) was synthesized from carbon dioxide (CO 2 ), propylene oxide (PO) and pyromellitic dianhydride (PD) using Zn–Fe(III) double metal cyanide (DMC) as a catalyst. The thermal properties of PPCPD were investigated with thermogravimetric analysis (TGA) and differential thermal gravity (DTG). TGA and DTG curves of PPCPD indicate that the decomposition process of PPCPD includes 2 stages: the chain scission decomposition stage (1st decomposition stage) and the chain unzipping decomposition stage (2nd decomposition stage). According to the Flynn–Wall–Ozawa method, the average apparent activation energies ( E a ) of 1st and 2nd decomposition stages are 98.95 kJ/mol and 150.39 kJ/mol, respectively. The result shows that the chain unzipping decomposition is difficult compared with the chain scission decomposition in the process of PPCPD decomposition. Furthermore, according to the Phadnis–Deshpande model, the degradation kinetic models of 1st and 2nd decomposition stages of PPCPD follow a phase boundary mechanism and a 3-dimensional diffusion mechanism, respectively.
研究领域:
材料科学
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化学工程
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DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2018
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IF 3.141
Zichao Guo,Wei Feng,Shiran Li,Peng Zhou,Liping Chen,Wanghua Chen
To prevent thermal runaway incidents in semibatch reactors (SBRs), designing thermally safe operating conditions should be considered first. Regretfully, determination of the reaction kinetics for organic reactions is a time-consuming and money-consuming process, especially in the fine chemical and pharmaceutical industries. Therefore, it is desirable to develop kinetic-parameter-free methods that can design the right operating conditions. Along this line, a new facile approach to design thermally safe operating conditions for isoperibolic homogeneous SBRs has been developed in this article. This approach is developed on the basis of deep insights into the phenomenon that the MTSR vs reaction temperature profiles for isothermal exothermic reactions present an “S” shape. The approach has been experimentally validated using the hydrolysis reaction of acetic anhydride. However, more work should be carried out to extend this method to more complex reaction systems, like consecutive reactions.
研究领域:
化学工程
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安全工程
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DOI
高影响因子
ACS Sustainable Chemistry & Engineering
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2015
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IF 4.642
Ming-Jie Chen,Qing-Shan Shi
The major challenges for directly converting lignocellulosic biomass into available materials in place of synthetic polymer materials are the complex chemical–physical structure and the narrow processing windows of the resources. In the present study, homogeneous chemical modification of sugarcane bagasse with phthalic anhydride was taken to be an improved strategy to meet the challenges. FT-IR and liquid-state NMR spectra confirmed the chemical structure of the sugarcane bagasse phthalates. Sugarcane bagasse phthalates with weight percentage gain higher than 32.9% were readily dissolved in organic solvents, and film materials were prepared by solution casting from the sugarcane bagasse phthalates. Thermogravimetric analysis and differential scanning calorimetry was applied to study the thermal behaviors of the sugarcane bagasse phthalates. Scanning electron microscope, atomic force microscopy and tensile testing were applied to study the morphologies and mechanical properties of the films. The results indicated that sugarcane bagasse was plasticized by homogeneous chemical modification with phthalic anhydride.
研究领域:
材料科学
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生物质能
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化学工程
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DOI
高影响因子
FIBERS AND POLYMERS
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2018
·Vol. 19
·期 9
·1850-1860
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IF 1.353
Bismark Sarkodie,Zhu Zhifeng
The objectives of this work were to survey the effect of amphipathic modification of starch on the adhesion to cotton fibers for improving the adhesion of starch to cotton in warp sizing. The amphipathic starch (AS) with oleophilic octenylsuccinate and hydrophilic phosphate substituents was prepared by the phosphorylation with sodium tripolyphosphate (STP) followed by the octenylsuccinylation with 2-octenylsuccinic anhydride (OSA). Two series of AS samples with differential total degrees of substitution ( DS t ) and substituent ratios of phosphates to octenylsuccinates were evaluated by fourier transform infrared (FTIR) analysis, degree of substitution, adhesion to cotton and surface tension. The adhesion of the starch to fibers was investigated using a legal method (FZ/T 15001-2008). The FTIR spectra revealed that octenylsuccinates and phosphates have been attached to the backbones of the starch. The amphipathic modification of starch with STP and OSA was an effective method to enhance the adhesion of corn starch to cotton. The strong adhesion of the AS to cotton was attributed to the reduced surface tension arisen from oleophilic octenylsuccinate and hydrophilic phosphate substituents and increased steric hindrance of the substituents introduced onto starch. The investigation showed that the improvement in the adhesion of the starch after amphipathic modification could be buttressed by the tensile strength of cotton yarns sized with AS. It was found that the AS was desizable and showed satisfactory desizing efficiency in oxidant desizing. Based on the adhesion, reaction efficiencies, and desizability, the AS with a total DS t of 0.033 and a substituent ratio of DS p 0.014/ DS o 0.032 showed potential for use in warp sizing.
研究领域:
材料科学
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纺织工程
·
高分子化学
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2017
·Vol. 135
·期 6
·45831
·
IF 1.86
Jing Zhang,Liqun Chen,Jiada Chen,Dan Wu,Jie Feng
We demonstrated an extremely facile way to fabricate inorganic–organic microgels with pH sensitivity and fluorescence. Aqueous dextran microgels are crosslinked by ZnO quantum dots (QDs). The ZnO@Dextran microgels were synthesized by simply mixing amino-modified ZnO (ZnO QDs) with carboxymethyl dextran (CMD) while stirring. The hybrid microgels showed an average diameter of ∼5 μm and strong fluorescence under ultraviolet (365 nm) irradiation. Up to 79.3 wt % of ZnO QDs were loaded into microgels. The ZnO QDs crosslinkage in the hybrid microgels structure enabled the microgels to degrade under mild acidic environment due to pH sensitivity of ZnO QDs. After loading of doxorubicin (Dox), the microgels were used as drug carriers for pH-controlled release of Dox. The degradation of the microgels and the release of loaded cargos could be monitored by detecting fluorescence intensity of the microgels. Moreover, owing to the cytotoxicity of ZnO QDs at their destination, drug-loaded ZnO@Dextran microgels can be used for synergistic therapy. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135 , 45831.
研究领域:
材料科学
·
生物医学工程
·
纳米医学
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DOI
高影响因子
危险品化学品经营许可证（带存储）