CARBOHYDRATE POLYMERS
·
2020
·
IF 7.182
Wenfeng Ni,Zhiming Zheng,Hui Liu,Peng Wang,Li Wang,Han Wang,Xiaowen Sun,Qiang Yang,Hengfang Tang,Genhai Zhao
Prenyltransferase NovQ immobilized carboxymethyl cellulose magnetic nanoparticles (NCMNs) were successfully synthesized via a valuable approach integrated from nanocomposite preparation, and applied for the production of vitamin K 2 using menadione hydroquinol and dimethylallyl diphosphate (DMAPP) as substrates. To investigate the interaction between nanoparticles and NovQ, we characterized the nanocomposite, and revealed that carboxymethyl cellulose (CMC) and Fe 3 O 4 formed a core-shell structure to absorb NovQ in the reaction systems, resulting from the high affinity of immobilized materials. Meanwhile, NCMNs with excellent pH and temperature tolerance, enhanced prenylated activity, and improved stability were found. Molecular docking analysis was also conducted to justify the contribution of multiple amino acids and effect of nanoparticles on catalytic properties of NovQ. Taken together, our study introduces a promising strategy to prepare magnetic nanoparticles and improve the performance of catalyst, which aims for opening new orientations for synthesis of magnetic nanoparticles used for prenyltransferase immobilization.
研究领域:
纳米技术
·
生物化学
·
酶学
✓ 已验证
DOI
PubMed
高影响因子
SYNTHETIC COMMUNICATIONS
·
2015
·
IF 0.929
Mingguang Zhu,Fafu Yang,Hongyu Guo,Congcong Li
Two novel triphenylene-aminoanthraquinone dimers 4a and 4b were synthesized by reacting triphenylene carboxyl derivatives 3a or 3b with 2-aminoanthracene-9,10-dione in yields of 80% and 78%, respectively. Their structures were confirmed by 1H NMR, electrospray ionization (ESI-MS), and elemental analysis. Their mesomorphic properties were studied by diffraction scanning calorimetry (DSC), polarizing optical microscopy (POM), and x-ray diffraction (XRD). The mesomorphic results suggested that they possess excellent mesophase properties. The investigation of fluorescence properties indicated that the strong cooperating fluorescence actions exist between two structural units. The fluorescence of dimers 4a and4b are seriously quenched due to the electron transfer from donor (triphenylene unit) to acceptor (aminoanthraquinone unit).
研究领域:
有机化学
·
材料科学
✓ 已验证
DOI
高影响因子
Natural Product Communications
·
2025
·
IF 1.4
Jie Xu,Yanfang Yang,Qianqian Li,Ziyi Dong,Yaoyang Guo,Zhansheng Jiang
ObjectivesThe current work aimed to isolate and identify new interesting small-molecule natural products from the leaves of a well-known medicinal plant Morus alba.MethodsThe ethanol extract of M. alba leaves was partitioned between EtOAc and water, and the EtOAc soluble part was fractionated by macroporous resin column chromatograph (CC) eluted with gradient EtOH. The 80% EtOH eluate was subject to silica gel, reversed phase C18, MCI gel and Sephadex LH-20 CC and finally purified by HPLC to afford four minor compounds 1–4, and the racemic 1 and 2 were further separated by chiral columns. Structural elucidation of these isolates was achieved via spectroscopic means especially HR-ESIMS and NMR, with the absolute configurations of new compounds assigned by ECD analyses. The cytotoxic screening was performed by MTT assay.ResultsA pair of new quinone enantiomers (1a/1b), a pair of new stilbenoid enantiomers (2a/2b), a known prenyl stilbenoid (3) and a known dihydrochalcone (4) were isolated and structurally characterized from the leaves of M. alba. They did not show significant cytotoxicity against MDA-MB231, A549, Hela and 4T1 tumor cell lines.ConclusionsThe M. alba leaves represent a rich source of new natural products, and the currently obtained constituents did not exert obvious growth inhibitory activity against the tested tumor cell lines. The bioactivities of the new isolates deserve further exploration in the future.
研究领域:
天然药物化学
·
植物化学
·
分子生物学
·
药用植物学
·
药物代谢
✓ 已验证
DOI
高影响因子
Materials Today Energy
·
2019
·
IF 0
Lijing Yan,Xiaomin Zeng,Zeheng Li,Xiangjuan Meng,Di Wei,Tiefeng Liu,Min Ling,Zhan Lin,Chengdu Liang
Graphite was reported by J.O. Besenhard as the reservoir for alkali ions in 1974. The booming period of lithium-ion batteries arrived after the graphite patent issued by Sony Co. in 1991. The flourish development is due to the address of lithium dendrite issue through the substitution from lithium metal to graphite. Currently, the zinc dendrite formation in zinc-ion batteries is one of the major issues. Herein, we fabricate a zinc-ion full battery by replacing zinc metal with organic quinone , which is a zinc dendrite free material. This novel zinc-ion full battery exhibits excellent cycling stability with capacity retention of 94.4% and high specific capacity of 189.5 mA h g −1 after 500 cycles. Ascribed to the low cost of quinone and long cycle performance, this work could inaugurate a new era for rechargeable aqueous zinc-ion batteries.
研究领域:
材料科学
·
能源存储技术
✓ 已验证
DOI
RSC Advances
·
2015
·Vol. 5
·期 39
·30631-30639
·
IF 3.84
Haiyan Mao,Fan Yang,Chaoxia Wang,Youjiang Wang,Donggang Yao,Yunjie Yin
Dye-bonded blocked waterborne polyurethanes were developed to synchronously realize coloring and finishing of textiles and improve colorfastness using an anthraquinone chromophore and a methyl ethyl ketoxime blocking agent. The number-average molecular weight of the dye-bonded blocked polyurethane is 2303 g mol−1 and the polydispersity is 1.06, indicating a narrow molecular weight distribution. The maximum absorption wavelengths do not shift after the monomolecular chromophores are bonded to the polyurethane. The self-colored polyurethanes provide better centrifugal stability and water solubility than the dye-mixed blocked polyurethanes. The dye-bonded blocked polyurethane offers good thermal stability below 100 °C and undertakes de-blocking at about 150 °C. The covalent bonding of the anthraquinone moiety with the polyurethane chain and temporary blocking of the terminal isocyanate groups are conducive to enhancing the tinting strength and colorfastness of the treated cotton fabrics. The self-colored blocked polyurethanes with good elasticity and toughness can improve the recovery angle of the treated cotton up to 120°, which can also endow the fabric with wrinkle resistance.
研究领域:
材料科学
·
纺织化学
·
染料化学
✓ 已验证
DOI
高影响因子
ACS Applied Polymer Materials
·
2024
·
IF 4.4
Kai Wang,Quanlu Wang,Guoxiang Tang,Tong Zhang,Wei Li,Tingxi Li,Ying Chen,Haijiao Xie,Yongqin Han
The applications of metal–organic frameworks (MOFs) with intrinsic porous structures are still limited by their low electrical conductivity. Herein, different anthraquinone-based dopants bearing with hydroxyl and sulfonate groups are introduced in situ and anchored on the surface of MOFs to enhance the electrical conductivity during the polymerization of Ni-MOF/polypyrrole (PPy) composites. The doping effect and electrochemical storage mechanism of MOF/PPy composites are investigated using supported experiments and density functional theory. Results show that among the three redox dopants, AQS demonstrates the highest doping level. The specific capacitance of the resulting Ni-MOF/PPy/AQS-12 can reach a high value of 667 F g–1 at the current density of 1 A g–1. The assembled Ni-MOF/PPy/AQS-12//active carbon asymmetric supercapacitor device have energy and power densities of 46.7 W h kg–1 (83.3 μWh cm–2) and 400 W kg–1(800 μW cm–2), excellent cyclic stability with a capacitance of 90.5% retention after 10000 cycles, and flexible stability, offering great potential as a power source for flexible wearable devices.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Tianchang Miao,Ximeng Lv,Fangshuai Chen,Gengfeng Zheng,Qing Han
Achieving O 2 photoreduction to H 2 O 2 with high selectivity control and durability while using easily accessible catalyst requires new synthesis strategies. Herein, we propose an asymmteric Sb coordination active center strategy of introducing anthraquinone (AQ) and heptazine to form local N 3 − Sb − O coordination by a rapid and simple explosive crystallization approach, resulting in a mesoporous conjugated heptazine-amide-AQ polymer coordinated Sb (HAAQ-Sb). It is demonstrated that the N 3 − Sb − O coordination effectively suppresses the charge recombination and acts as the highly active site for O 2 adsorption. Moreover, as-introduced AQ units initiate low-barrier hydrogen transfer through a reversible redox process that triggers highly-efficient H 2 O 2 production. A superior apparent quantum yield of 20.2 % at 400 nm and a remarkable solar-to-chemical conversion efficiency of 0.71 % are achieved on the optimal HAAQ-Sb, which is the highest among C 3 N 4 -based photocatalysts at present. This asymmetric coordination concept and material design method provide new perspectives for the research of novel catalysts toward artificial photosynthesis.
研究领域:
材料科学
·
光催化
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2024
·
IF 8.1
Jingyao Wang,Jingqiu Jiang,Hongxia Zhao,Zhansheng Li,Xintong Li,Shafiul Azam,Baocheng Qu
Halobenzoquinones (HBQs) are a novel family of unregulated disinfection byproducts (DBPs). Little is known about their phototransformation activities in natural water. Here, five HBQs with various halogenated substituent types, numbers, and structures positions were selected to investigate the kinetics of degradation in aqueous solutions at various concentrations and in the presence of common environmental variables (Cl − , NO 2 − , and humic acid). The results indicated that dichloride and dibromo-substituted HBQs were photolyzed, whereas tetrachloro-substituted HBQs showed little degradation. The photolysis rate constant ( k ) of HBQs decreased with increasing initial concentration. The presence of NO 2 − and Cl − promoted the degradation of HBQs mainly through the formation of hydroxyl radical (•OH), which were confirmed by electron paramagnetic resonance (EPR). In contrast, humic acid played a negative role on HBQs transformation due to the adsorption and quenching reactions. Possible conversion pathways for HBQs were proposed based on the identification of two major photodegradation products, hydroxylated HBQs and halogenated-benzenetriol, as well as reactive free radicals . This study provided meaningful insights into the environmental fates and risk assessments of HBQs in natural aquatic system.
研究领域:
环境科学
·
水处理工程
·
化学动力学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Ping Wang,Qiulian Chen,Chengxin Xiang,Guonian Zhu,Yue Luo,Kerage Dorothy Mokeira,Yong Chen,Jialun Wu,Xiaoling Hou,Shuxia Xu
Tetrachlorobenzoquinone (TCBQ) as one of the most toxic quinones has potential risk of causing canceration, and the monitoring of TCBQ in the environment is of significant importance. In this study, a flowerlike Co-PTA-400(Ar) metal organic frameworks (MOF) catalyzed TCBQ-H 2 O 2 chemiluminescence (CL) system was established for sensitive determination of trace TCBQ in environmental waters. The reaction between TCBQ and H 2 O 2 can result in weak CL emission, and the CL signal was enhanced about 10-fold using flowerlike Co-PTA-400(Ar) as catalyst. The luminescence mechanism was investigated through kinetic studies and free radical scavenging experiments. The strong CL emission of TCBQ mainly relied on the generation of abundant •OH by the catalysis of Co-PTA-400(Ar). This strategy allows to develop a highly sensitive method for the determination of TCBQ in the linear range of 1 ∼ 50 μM, with a detection limit of 0.56 μM (3 σ ). The proposed method was applied for analysis of three spiked water samples with recoveries ranging from 95.7% to 100.5%. This method offering the advantages of rapid analysis, low costs, and high sensitivity, is appealing for detection of TCBQ in environmental waters.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2021
·Vol. 11
·期 7
·1757
·
IF 5.076
Xiaohua Ma,Dehua Deng,Ning Xia,Yuanqiang Hao,Lin Liu
Nanocatalysts are a promising alternative to natural enzymes as the signal labels of electrochemical biosensors. However, the surface modification of nanocatalysts and sensor electrodes with recognition elements and blockers may form a barrier to direct electron transfer, thus limiting the application of nanocatalysts in electrochemical immunoassays. Electron mediators can accelerate the electron transfer between nanocatalysts and electrodes. Nevertheless, it is hard to simultaneously achieve fast electron exchange between nanocatalysts and redox mediators as well as substrates. This work presents a scheme for the design of electrochemical immunosensors with nanocatalysts as signal labels, in which pyrroloquinoline quinone (PQQ) is the redox-active center of the nanocatalyst. PQQ was decorated on the surface of carbon nanotubes to catalyze the electrochemical oxidation of tris(2-carboxyethyl)phosphine (TCEP) with ferrocenylmethanol (FcM) as the electron mediator. With prostate-specific antigen (PSA) as the model analyte, the detection limit of the sandwich-type immunosensor was found to be 5 pg/mL. The keys to success for this scheme are the slow chemical reaction between TCEP and ferricinum ions, and the high turnover frequency between ferricinum ions, PQQ. and TCEP. This work should be valuable for designing of novel nanolabels and nanocatalytic schemes for electrochemical biosensors.Keywords:electrochemical immunosensor;nanocatalyst;redox cycling;quinone
研究领域:
生物传感
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
ELECTROANALYSIS
·
2019
·Vol. 32
·期 1
·142-148
·
IF 2.691
Yue Zhang,Ziyao Lv,Jie Zhou,Yan Fang,Hao Wu,Fengxue Xin,Wenming Zhang,Jiangfeng Ma,Ning Xu,Aiyong He,Weiliang Dong,Min Jiang
In this study, stable CotA laccase from Bacillus subtilis 168 was adsorbed on electrode modified with a thiol graphene-gold nanoparticle (thGP-AuNPs) nanocomposite film. The novel bacterial laccase biosensor was employed for quantitative detection of hydroquinone (HQ) and the electrochemical properties of this laccase biosensor were investigated. The results indicate that the immobilized CotA shows great oxidation activity towards HQ in the presence of oxygen and the biosensor shows linear electrocatalytic activity in the concentration range from 1.6 to 409.6 μM, with a detection limit of 0.3 μM. Further, the CotA modified electrode, when compared to fungal laccase-modified biosensors, shows better alkaline stability (retaining approximately 80 % and 70 % of response current at pH 8 and 9, respectively) and reusability (retaining ∼87 % of response current after 100 days). The development of this new kind of laccase on a biosensor will offer a novel tool for substance detection applications in hostile environments, especially for industrial pollutants.
研究领域:
生物技术
·
环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
·
2011
·
IF 1.378
Wenhua Song,Jing Guo,Feng Ding,Weixuan Hu,Zhen Li,Minling Gao
The acute toxicities of the six naphthoquinone compounds on Daphnia magna ( D. magna ) at 48 h were classified as harmful, toxic, and very toxic. The results indicated that log P played an important part in the toxicity of compounds to organism. And 1-carbonyl or the other hydrophobic substituents of the naphthoquinone compounds are likely to mediate the binding of the compound to the target via hydrogen bonding and hydrophobic interactions. Our results provided a foundation for further investigation using 3D-QSAR and HQSAR to evaluate the aquatic ecological risk and the mechanism of toxicity of naphthoquinones.
研究领域:
生态毒理学
·
环境科学
·
药物化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）