Advanced Healthcare Materials
·
2023
·
IF 10
Hai-Feng Liang,Yan-Pei Zou,An-Nan Hu,Ben Wang,Juan Li,Lei Huang,Wei-Sin Chen,Di-Han Su,Lan Xiao,Yin Xiao,Yi-Qun Ma,Xi-Lei Li,Li- Bo Jiang,Jian Dong
Bone matrix has distinct architecture and biochemistry which present a barrier on synthesizing bone-mimetic regenerative scaffolds. To mimic the natural structures and components of bone, we prepared the biomimetic structural decellularized extracellular matrix (ECM)/regenerated silk fibroin (RSF) scaffolds incorporated with magnetic nanoparticles (MNP) using a facile synthetic methodology. The ECM/RSF/MNP scaffold is hierarchically organized and interconnected porous structure with silk fibroin twined on the collagen nanofibers, mimicking the bone minimum unit morphology. The scaffold demonstrated saturation magnetization due to the presence of MNP, along with good cytocompatibility. Moreover, the β-sheet crystalline domain of RSF and the chelated magnetic nanoparticles could mimic the deposition of hydroxyapatite and enhance compressive modulus of the scaffold by approximately 20%. The results indicated that an external static magnetic field (SMF) with a magnetic responsive scaffold effectively promoted cell migration, osteogenic differentiation, neogenesis of endotheliocytes in vitro and new bone formation in a critical-size femur defect rat model. RNA sequencing revealed that the molecular mechanisms underlying this osteogenic effect involve calsequestrin-2-mediated Ca 2+ release from the endoplasmic reticulum to activate Ca 2+ /calmodulin/calmodulin-dependent kinase II signaling axis. Collectively, bionic magnetic scaffolds with SMF stimulation provide a potent strategy for bone regeneration through internal structural cues, biochemical composition and external physical stimulation on intracellular Ca 2+ homeostasis. This article is protected by copyright. All rights reserved
研究领域:
组织工程
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生物材料
·
再生医学
·
生物医学工程
·
细胞生物学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2024
·
IF 3.8
Zheng Zhang,Shuai Tang,Kai Ge,Kangjun Wang,Yuanhui Ji
The scaling phenomenon poses a great challenge for industrial production because of its widespread presence and the complex scaling process. Hence, we report a novel terpolymer (PIA-SAS-AM) scale inhibitor with high efficiency to obstruct the formation of calcium sulfate. Furthermore, the scale inhibition performance and mechanism were further evaluated and systematically investigated. Herein, the various influence factors (monomer ratio, polymerization temperature, initiator content, etc.) on scale inhibition were discussed in detail. By various characterization methods, the terpolymer scale inhibitor was identified, consistent with the expected structure. Based on the static scale inhibition method, the performance of the copolymer on the control of the CSD (calcium sulfate dihydrate) scale was also explored under different external environments (copolymer concentration, retention temperature, calcium concentration, etc.). Especially, the scale inhibition efficiency of CSD reached nearly 100% when the concentration of the copolymer was 16 mg/L. Additionally, the prepared terpolymer scale inhibitor has great aqueous solubility, salt, and heat resistance. This work provides novel insights into inhibiting crystal scaling and offers further guidance on polymer scale inhibitor design.
研究领域:
材料科学
·
化学工程
·
高分子化学
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产品关联
DOI
高影响因子
ENERGY & FUELS
·
2020
·
IF 3.421
Jiatao Xiang,Zhen Zhang,Luning Tian,Qinghua Zhao,Haiping Yang,Xiong Zhang,Jingai Shao,Shihong Zhang,Hanping Chen
In order to enhance wet flue gas desulfurization efficiency and reduce cost, the effects of different series of additives (typical organic acids, organic salts, inorganic salts, organic amines, and their mixture) on the desulfurization properties, including pH buffering characteristics of slurry, dissolution characteristics of CaCO3, oxidation characteristics of CaSO3, desulfurization efficiency, and economic cost were investigated in this work. The results show that the pH buffering capacity is sodium benzoate ≈ Na2SO4 > adipic acid > double oxazine. The dissolution promoting effect of CaCO3 is acetic acid > double oxazine ≈ sodium acetate > MgSO4. The additives that can significantly promote the oxidation of CaSO3 are adipic acid, citric acid, acetic acid, MgSO4, and Na2SO4. Without an additive, the desulfurization efficiency of CaCO3 slurry decreased to 85.87% after 4 h. After the addition of the composite additive (CA-3), the desulfurization efficiency of CaCO3 slurry remained 96.53% for 4 h, increasing by 10.66%. The main reasons for the enhancement in the desulfurization process may be a collection of three factors: the reversible hydrolysis reactions of acetic acid and sodium acetate, the formation of an acid–base conjugate system by sodium benzoate, and the formation of a neutral ion pair MgSO3 by MgSO4 in the slurry. In addition, the composite additive has been used in the Dabie mountain power plant of China. The economic benefit analysis shows that the desulfurization unit of 4 × 640 MW coal-fired power plant can save 1.26 million dollars per year by composite additive.
研究领域:
环境科学
·
化学工程
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DOI
高影响因子
CEMENT & CONCRETE COMPOSITES
·
2022
·
IF 9.93
Xingyi Zhu,Chenghong Lu,Wenkai Li,Siqi Zhou,Feng Li,Jianzhuang Xiao,Surendra P. Shah
This paper discusses the different modifying mechanisms of carbon nanofiber (CNF) on the geopolymers with different calcium contents . First, the rheological and mechanical properties of CNF modified geopolymers with low and high-calcium content are measured. Results show that the modifying effect on rheological properties is more obvious on high-calcium geopolymers. The compressive and flexural strength of low-calcium geopolymers decrease, while the compressive and flexural strength of high-calcium geopolymers significantly improve. Based on XRD , MIP , and SEM analyses, it can be concluded that CNFs help to produce refined hydration products in high-calcium geopolymers, resulting in a denser structure. Promoting hydration can counteract the adverse effect caused by the agglomeration of CNFs. CNFs have a positive effect on high-calcium geopolymers in general. However, hydration reaction rarely happens in the low-calcium geopolymers because of the low calcium content, and XRD results show that CNFs do not significantly promote the geopolymerization reaction. Moreover, the agglomeration of CNFs leads to a decrease in compactness. CNFs negatively affect low-calcium geopolymers. Generally, CNFs can be applied in high-calcium geopolymers to form a denser structure and improve the mechanical properties.
研究领域:
材料科学
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土木工程
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DOI
高影响因子
Journal of Materials Chemistry A
·
2022
·Vol. 10
·期 39
·20827-20836
·
IF 14.511
Linyuan Li,Guobin Zhang,Xianming Deng,Jing Hao,Xu Zhao,Hongfei Li,Cuiping Han,Baohua Li
Abundant reserves of calcium in the earth's crust are expected to give calcium-ion batteries (CIBs) a price advantage. Nevertheless, the strong electrostatic interaction between calcium ions and battery host materials leads to low specific capacity and poor cycle performance. More reliable electrode materials need to be studied. Here, we report a covalent organic framework (COF) synthesized using 2,5-diaminohydroquinone dihydrochloride (Hq) and 1,3,5-triformylphloroglucinol (Tp) , HqTp, as an organic electrode anode material for Ca-ion storage in aqueous electrolytes. The COF provided high specific capacity (up to 119.5 mA h g−1 at 1 A g−1) and outstanding rate performance, maintaining 78.7 mA h g−1 even at an extremely high current of 50 A g−1. Mechanism studies using Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy revealed the reversible calcium insertion/extraction behavior with carbonyl as the active site. The remarkable rate performance largely benefits from the storage mechanism of the pseudocapacitance behavior. The co-insertion of protons and calcium ions and the in situ conversion of C–OH groups of HqTp to CO groups was observed, which led to an activation. Finally, a full cell with HqTp and activated carbon as the active materials was assembled. The full cell provides an average working voltage of 0.6 V with a 73.7% capacity retention (0.0164% reduction per cycle) for 1600 cycles. This study demonstrates the potential for the COF material as the active host material for CIBs.
研究领域:
材料科学
·
电化学
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Dan Zhang,Xiaofeng Wang,Zhiping Fan,Yixing Zhao,Xuefeng Xia,Fan Li
The two-dimensional–three-dimensional (2D–3D) heterostructured perovskite solar cells (PSCs) have drawn widespread interest, wherein the organic spacer plays a significant role in the photovoltaic performance. Herein, a novel π-conjugated organic spacer with the aggregation-induced emission (AIE) property, (Z)-2-([1,1′-biphenyl]-4-yl)-3-(5-(4-(3-aminopropoxy)phenyl)thiophen-2-yl)acrylonitrile (BPCSA-S), is designed and synthesized, which is successfully applied for the in situ construction of 2D–3D heterostructured PSCs via the two-step solution method. By virtue of the functional groups (i.e., cyano, thiophene, and amino) in BPCSA-S, the BPCSA-S organic spacer can trigger the in situ growth of 2D perovskites, which will serve as the template for the heteroepitaxial growth of 3D perovskites, thus obtaining a 2D–3D heterostructured film with high-quality and few defects. More pleasingly, benefiting from the AIE property and delocalized π-electrons in the π-conjugated BPCSA-S organic spacer, excellent photosensitization process and carrier transport can be achieved. Consequently, the resultant 2D–3D heterostructured PSCs yield a pleasing PCE of 22.07%, accompanied by mitigatory hysteresis, as well as enhanced stability. Our research shows a hopeful multifunctional organic spacer approach using the novel π-conjugated AIE organic spacer for high-performance PSCs.
研究领域:
材料科学
·
能源技术
·
光伏器件
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产品关联
DOI
PubMed
高影响因子
Nature Photonics
·
2025
·
IF 32.9
Yang Xuke,Ma Tianjun,Hu Haojun,Ye Wenjiang,Li Xin,Li Mingyu,Zhang Afei,Ge Ciyu,Sun Xianglang,Zhu Yongxin,Yan Shuyu,Yan Jun,Zhou Ying,Li Zhong’an,Chen Chao,Song Haisheng,Tang Jiang
All-perovskite tandem solar cells are promising as next-generation high-efficiency photovoltaic devices. However, further progress in tin-lead (Sn–Pb) mixed perovskites, which are essential as the narrow-bandgap bottom sub-cell, is hampered by unbalanced crystallization processes, leading to inhomogeneous films and reduced power conversion efficiency (PCE). Here we provide a complete understanding of the formation of Sn–Pb films, from the precursor solution to the final film. We find that the total crystallization barrier for Sn-based perovskites is limited by the desorption of dimethyl sulfoxide (DMSO), while Pb-based perovskites experience a smaller DMSO desorption barrier. By engineering the reaction barrier in mixed films via tailoring the DMSO content, we obtain synchronous Sn–Pb perovskite crystallization and high-quality homogeneous films. On the basis of this understanding, we demonstrate single-junction Sn–Pb perovskite solar cells with a PCE of 22.88% and all-perovskite tandem devices with a certified PCE of 28.87%, fabricated by antisolvent-free methods. The unencapsulated tandem devices retain 87% of their initial PCE after about 450 h with maximum power point tracking under 1 sun illumination.
研究领域:
材料科学
·
能源科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2023
·Vol. 170
·期 12
·122505
·
IF 3.9
Yongxin Wu,Muya Cai,Hongya Wang,Zuojun Hu,Fangzhao Pang,Xiang Chen,Meiyu Zhao,Bingbing Wang,Xiong Zhang,Xiaowei Liu,Dihua Wang,Huayi Yin
Lead-acid batteries (LABs) are commonly utilized in various applications such as electric motorcycles, uninterruptible power systems, and stationary energy storage devices. Calcium (Ca) is an essential element being added to Pb grid alloys to increase their mechanical strength. In this paper, molten salt electrolysis is used to prepare Pb-Ca master alloy in molten CaCl2-NaCl at 700 °C. The Ca concentration reaches 2.51 wt%, and the current efficiency reaches 85.0% for the 1 A-scale electrolyzer and 75.8% for the 50 A-scale cell. Compared with the traditional physical mixing ways, Ca is selectively and gradually deposited in the liquid Pb cathode without worrying about the immense heat generated by mixing Ca and Pb. In addition, molten salt serves as a media to avoid the oxidation of Ca. Through thermodynamic calculations and electrochemical measurements, the Pb-Ca formation prefers to happen rather than Pb-Na alloy in molten CaCl2-NaCl because of the stronger interaction of Ca and Pb than Na and Pb. Overall, this paper provides a straightforward strategy to prepare Pb-Ca master alloys, which can be expanded to prepare various liquid semimetal alloys containing reactive metals.
研究领域:
材料科学
·
冶金工程
·
电化学
·
能源材料
·
功能合金
✓ 已验证
DOI
高影响因子
CRYSTENGCOMM
·
2019
·Vol. 21
·期 27
·4085-4091
·
IF 3.382
Xiaohua Cheng,Lin Jing,Ye Yuan,Songjie Du,Qing Yao,Jie Zhang,Jianxu Ding,Tianliang Zhou
Due to their excellent luminescent properties such as high stability, narrow band emission, and strong luminescence, hybrid organic–inorganic lead perovskites have great potential for application in optoelectronic devices. Compared to their conventional 3D counterparts, 2D perovskites exhibit enhanced moisture stability. Moreover, with the enhancement of exciton binding energy and limitation of charge carriers, 2D layered perovskites are considered ideal candidate materials for efficient light-emitting diodes (LEDs). However, hybrid organic–inorganic lead perovskites contain highly toxic Pb, which is considered as a major environmental pollutant and health hazard. Therefore, the further larger-scale applications are limited. Thus, exploiting the impressive properties and practical applications of 2D layered structure Pb-free hybrid organic–inorganic perovskites in the LED field is necessary. In the present work, a centimeter-size square 2D layered Pb-free (CH3NH3)2MnCl4 single crystal was grown successfully with diverse crystal morphologies from two different solutions. This material could be excited by light in different wavelength bands. The main peak in its emission spectrum is located at 608 nm and the full width at half maximum (FWHM) is 72 nm. Furthermore, we prepared an LED using the (CH3NH3)2MnCl4 single crystal, which exhibited good luminescence properties, emitting obvious red light with a QE of 2.4% upon excitation at 417 nm and used for white light illumination.
研究领域:
材料科学
·
光电子学
·
无机化学
·
晶体生长
·
发光二极管
✓ 已验证
DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 100
·82247-82251
·
IF 3.84
Yingchun Su,Wei Zong,Xiaole Zhao,Shenghua Ma,Xiaojun Han
This paper reported a crystallization – dissolution – interface mineralization (CDIM) method on synthesizing calcium carbonate (CaC) and calcium phosphate (CaP) inorganic microcapsules with good biocompatibility and good pH sensitivity. The method is based on mineralization at the ethanol/water interface. The microcapsules were formed in a few seconds and did not need post treatment for removing the templates. The diameters of the microcapsules can be controlled by the size of the crystal clusters regulated by stirring time. Carboxyfluorescein (CF) molecules as model drugs were encapsulated inside the capsules after coating with FeIII–polyphenol tannic acid (TA) films. The pH sensitive carboxyfluorescein molecule releasing behavior was investigated. The lower pH caused faster and thorough release of CF. The CDIM method can be applied for fabricating other inorganic microcapsules, which holds great potential for drug delivery.
研究领域:
材料科学
·
生物医学工程
·
药剂学
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产品关联
DOI
高影响因子
Advanced Electronic Materials
·
2020
·Vol. 6
·期 3
·1901291
·
IF 6.593
Tengling Ye,Qiao Wang,Changhao Tian,Ranbir Singh,Yaping Zhang,Zhiwei Liu,Xikui Fang,Dongqing He
Electronic skin (e-skin) has attracted extensive attention owing to its potential application in biomedical sensors, intelligent robots, and bionic prostheses. To imitate better or even surmount the perceptive capabilities of human skin, multifunctional e-skin is an important trend in the field. A novel stable perovskite intermediate gel (PIGel) is obtained during the MA 2 SnI 6 perovskite crystallization process. This Sn-based PIGel exhibits good conductivity and outstanding wettability on different polymer substrates. Based on these properties, it is successfully applied to the field of e-skin. Flexible and stretchable multifunctional e-skin sensors are developed based on it. Stretching, finger bending, voice recognition, pulse monitoring, temperature, and electricity response are achieved in one e-skin device. In addition, the MA 2 SnI 6 perovskite single crystal is prepared by solvent engineering. The formation mechanism of the PIGel and MA 2 SnI 6 single crystal is studied in detail. This work broadens the selection range of sensing materials for e-skin and paves the way to achieve multifunctional sensors with the facile fabrication process.
研究领域:
材料科学
·
生物医学工程
·
传感技术
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Chenglong Wang,Xiaolin Xu,Shuhan Xiong,Peipei Zhang,Jia Yuan,Xuzhu Gao,Wencai Guan,Fanchen Wang,Xin Li,Tao Leng,Hongjing Dou,Guoxiong Xu
Chemoresistance is the major reason for the failure of chemotherapy, which is a major cause of death in patients with advanced cancer. However, the current approach to reversing cancer chemoresistance is limited. Calcium ions are indispensable for all physiological activities of the body. Because a calcium concentration was reduced in chemoresistant cancer cells, we fabricated calcium-chelated nanoparticles upon self-assembly to replenish intracellular calcium ions in the cells. Through employing an amphipathic polyethylene glycosylated (PEGylated) lipids covalent bonding chelator molecule to bind calcium ions, the chelate calcium ions are used for the first time to reverse the chemoresistance of cancer cells. This nanoparticle released calcium ions more rapidly in a weakly acidic environment than in neutral and weak base conditions, which ensures the effective release of calcium ions in the acidic microenvironment of tumors. As assessed by in vitro and in vivo experiments, this calcium-chelated nanoparticle indeed restored calcium homeostasis and reversed chemoresistance in a variety of chemoresistant cancer cells, whereas calcium chloride solution did not increase the concentration of calcium ions in chemoresistant cancer cells. Furthermore, the mechanism study showed that calcium-chelated nanoparticles affected the expression of chemoresistant genes and promoted cancer cell apoptosis by inhibiting the NF-κB signaling pathway. In conclusion, our data provide direct insight into an effective approach for the reversal of chemoresistance and calcium-chelated nanoparticles may have potential applications for treating chemoresistant patients.
研究领域:
肿瘤学
·
纳米技术
·
药理学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）