Polymer Chemistry
·
2012
·Vol. 4
·期 5
·1425-1429
·
IF 5.321
Xinjia Yang,Buyi Li,Irfan Majeed,Liyun Liang,Xuejun Long,Bien Tan
Magnetic microporous polymer nanoparticles (MMPNs) with high surface area and superparamagnetic properties have been designed and synthesized successfully. Their application in removing toxic organic compound by adsorption and magnetic separation have been proved. The MMPNs were also evaluated for their ability to uptake and control the release of ibuprofen.
研究领域:
材料科学
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纳米医学
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药物递送
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环境修复
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生物材料
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药剂学
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Kejian Li,Yang Yang,Aziz-Ur-Rahim Bacha,Yiqing Feng,Saira Ajmal,Iqra Nabi,Liwu Zhang
Halogenated organic compounds (HOCs) like chlorophenols (CPs) are one of persistent organic pollutants in environment, and it is an urgent issue to remove HOCs efficiently because they are detrimental to aquatic organisms and human beings. Electrocatalytic hydrodechlorination (ECH) technique has been widely studied to deal with chlorophenols. However, litter attention has been paid to the further treatment of the dechlorination product phenol. Meanwhile, photoelectrocatalysis is regarded as a promising method for contaminants elimination and water splitting using inexhaustible solar energy. Therefore, this study proposed a photoelectrochemical reductive hydrodechlorination and sequential oxidation method for thorough degradation of 2,4-dichlorophenol (2,4-DCP) using WO 3 /Mo-doped BiVO 4 as photoanode and Pd/Ni foam as cathode. Several factors such as Pd-loading amount, initial pH, overpotential, and Cl − that would influence the efficiency of 2,4-DCP hydrodechlorination and phenol oxidation have been investigated in detail. The 2,4-DCP could be completely hydrodechlorinated to phenol, and removal efficiency of the obtained phenol reached ~45% for 4 h reaction under optimized conditions. Additionally, there was no secondary chlorinated pollutant generated during the oxidation process even though the existence of Cl − . Lastly, the possible mechanism and degradation pathway were also explored based on LC-MS. This study proposed an efficient and environmental-friendly technique for complete degradation of chlorophenols, which might be also suitable for other HOCs and would be industrialized with the help of further studies.
研究领域:
环境科学
·
电化学工程
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DOI
高影响因子
Food Bioscience
·
2025
·
IF 5.9
Yuening Li,Huipeng Liang,Yuzheng Wu,Xinping Lin,Yiwei Dai,Chaofan Ji
Mixed-culture fermentation can enhance cider aroma, but direct co-culture often limits the persistence of non- Saccharomyces yeasts. Among these species, Metschnikowia koreensis is noteworthy for its strong protease and lipase activities that release aroma precursors, yet its interaction with Saccharomyces cerevisiae has not been well characterized. This study evaluated sequential inoculation of M. koreensis and S. cerevisiae with 0 h, 24 h, and 48 h delays. A 48-h delay (SM 48 ) extended M. koreensis viability to 9 days, increased ethanol production, and produced sensory attributes characterized by lower sourness and astringency and higher umami and richness. The SM 48 group produced the most abundant and diverse volatile compounds, with key fruity and floral esters elevated. OPLS-DA identified these esters as major discriminant contributors, whereas compounds commonly associated with off-flavors such as acetic acid and hexanal were reduced. Metabolic pathway analysis indicated enhanced Ehrlich and esterification pathways with reduced acetate production. Multi-method validation supported that SM 48 cider exhibits more complex volatile profiles, stronger fruity and floral notes, and improved color. These results demonstrate that controlled sequential inoculation is an effective approach for improving cider aroma complexity and overall product quality.
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2025
·
IF 7.7
Shiao Yang,Zheying Mu,Jiazhu Pu,Weikang Ge,Kai Hu,Xuemei Jia,Genxi Li
Glycoproteins require sensitive detection for both biomedical research and clinical examination. Although existing strategies exploit glycosylation sites for recognition or signal labeling, they have not taken full advantage of glycoproteins’ potential as natural signal amplification platforms. To overcome the limitation, this study proposes a highly sensitive and modification-free electrochemical detecting strategy. Which employs a boronate derivative featuring dual-boronic acid groups. Through boronic acid-cis-diol specific interactions, the derivative simultaneously and directly co-immobilizes target glycoproteins and glycan-modified cascade enzymes via covalent polymerization. This forms an enzyme cascade amplification network, inducing methylene blue (MB) redox cycling to generate a differential pulse voltammetry (DPV) signal output. Using mucin 1 (MUC1) as a model target, the constructed biosensor achieves a detection limit of 116 fM with a wide linear range (0.2 pM-20 nM), meeting clinical requirements for glycoprotein quantification. The method also delivers promising results for MUC1 detection in clinical serum samples. Collectively, this work fully leverages the intrinsic potential of natural glycosylation sites on glycoproteins. The innovative dual-boronic acid “molecular grasper” strategy enables efficient and specific signal amplification, offering advantages including operational simplicity, cost-effectiveness, and rapid response. Ultimately, it provides a novel pathway for developing universal glycoprotein detection platforms, demonstrating significant value for disease diagnosis and biological research applications.
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产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2014
·
IF 4.258
Shao-Ting Wang,Wei Huang,Yi-Fan Deng,Qiang Gao,Bi-Feng Yuan,Yu-Qi Feng
The metal oxide affinity chromatography (MOAC) materials have been extensively used for extraction of phosphate compounds in the past decade. Actually, some of these materials also possess adsorption affinity towards cis -diol-containing compounds, which was seldom explored in separation field so far. Here we present the proof-of-concept study to evaluate the feasibility of expanding MOAC for specific capture of cis -diol biomolecules. Benefitting from the high commercialisation of the metal oxide materials, such MOAC strategy possesses several advantages, like synthesis-free, low cost and high expandability. Firstly, the recognition of adenosine against 2′-deoxyadenosine was performed using zirconium oxide and cerium oxide, two typical commercial MOAC materials. The results showed that efficient adsorption and elution could be achieved easily by pH switching from basic to acidic. The isotherm curves demonstrated the adsorption process fitted well with Freundlich isotherm model and was spontaneous at room temperature (Δ G 0 < 0) with an exothermic nature (Δ H 0 < 0). Afterwards, the highly efficient and selective enrichment of various model cis -diol biomolecules, including ribonucleosides, glycopeptides and glycoproteins, was achieved using this MOAC strategy. Finally, the endogenous ribonucleosides and modified ribonucleosides were successfully purified from human urine sample, which demonstrated the potential application of MOAC materials in the enrichment of target compounds from complex biological samples. Besides the excellent performance of extraction for cis -diol-containing compounds, equally important is that these materials are commercially available with low cost, which makes the MOAC a promising strategy for the study of cis -diol biomolecules in metabolomics and proteomics.
研究领域:
分析化学
·
生物化学
·
代谢组学
·
蛋白质组学
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DOI
高影响因子
EUROPEAN POLYMER JOURNAL
·
2018
·
IF 3.741
Qian Dong,Shuai-Shuai Chi,Xi-Yan Deng,Yao-Han Lan,Chao Peng,Lin-Yi Dong,Xian-Hua Wang
Boronate affinity (BA) monolith is an important tool for uniquely selective capture of cis -diol-containing compounds. However, most of BA monoliths suffer from limited binding sites. In this work, a high-capacity BA monolith was successfully synthesized via simple two-step atom-transfer radical polymerization method. Fourier transform infrared spectra, scanning electron microscope and Brunauer–Emmett–Teller surface area analyzer were used to characterize the resultant BA monolith. The BA monolith could selective capture of cis -diol-containing small molecular compounds and protein macromolecules with all aqueous mobile phase at pH of 8.5. Frontal analysis was applied to measure the adsorption data, and Scatchard equation was used to calculate the C (Q max ) and dissociation constants ( K d ). By using polymer chains to amplify the number of binding sites, the binding capacity of BA monolith had been effectively improved to 303.5 and 118.2 μmol g −1 for catechol and adenosine, respectively. Such binding capacity was the highest among already reported BA monoliths. Interestingly, the binding capacity was mainly depended on the molecular volume (or molecular weight) of cis -diol containing compounds with a significant negative correlation. Besides, via synergistic effect of double binding, the BA chains had enhanced the binding strength of BA monolith toward molecules with two cis -diol groups with K d value of 10 −5 M, which were lower than that of molecules with one cis -diol group by one order of magnitude. The results indicated that the binding capacity and strength depend on not only the property of BA materials but also the nature of cis -diol-containing compounds.
研究领域:
生物化学
·
材料科学
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DOI
高影响因子
Molecular Catalysis
·
2022
·
IF 5.089
Changjun Yang,Shuai Xu,Fanchang Peng,Wenyao Zhou,Quan Zhou,Xi Chen,Bingguang Zhang,Kejian Deng
The cis / trans isomeric effects of cobalt thioporphyrazine (CoPz) bearing 1,4-dithiin (A) and bis(butylthio) (B) groups on their photocatalytic performance were investigated by photocatalytic selective aerobic oxidation of 5-hydroxymethylfurfural (HMF) in aqueous solution under simulated sunlight. The results demonstrated that the cis -CoA 2 B 2 consistently showed higher photocatalytic activity than the trans -CoA 2 B 2 , especially in alkaline solution. Meanwhile, the cis -CoA 2 B 2 favored oxidizing HMF to 2,5-furandicarboxylic acid (FDCA), while the trans -CoA 2 B 2 preferred yielding 2,5-diformylfuran (DFF). Under alkaline conditions, the yield of FDCA can reach 73% with a selectivity of 95% in the presence of cis -CoA 2 B 2 after reacting 14 h, while 37% of DFF yield with a selectivity of 81% can be achieved in the presence of trans -CoA 2 B 2 after reacting 12 h. The relationship between the structure of cis / tr ans isomers and their photocatalytic performance was further explored by density functional theory (DFT) calculations. The active species originated from cis -CoA 2 B 2 and trans -CoA 2 B 2 were also examined by trapping experiments.
研究领域:
化学
·
材料科学
·
催化反应
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DOI
高影响因子
Polymers
·
2022
·Vol. 14
·期 14
·2872
·
IF 4.967
Zhengshi Li,Huimin Lin,Shanwei Shi,Kai Su,Guangsen Zheng,Siyong Gao,Xuan Zeng,Honglong Ning,Meng Yu,Xiang Li,Guiqing Liao
Bone healing is a complex process that requires the participation of cells and bioactive factors. Stromal derived factor-1 α (SDF-1α) and magnesium ions (Mg2+) both are significant bioactive factors for cell recruitment and osteogenesis during bone regeneration. Thus, a bifunctional hydrogel containing a sequential delivery system is fabricated to improve osteogenesis. During sequential delivery of the hydrogel, SDF-1α is predominantly released at the early stage of bone mesenchymal stem cells (BMSCs) recruitment, while Mg2+are constantly delivered at a later stage to improve osteogenic differentiation of recruited cells. In addition, due to the early release of SDF-1α, the hydrogel showed strong BMSCs recruitment and proliferation activity. Mg2+can not only induce up-regulation of osteogenic gene expression in vitro, but also promote bone tissue and angiogenesis in vivo. Taken together, the injection of xanthan gum-polydopamine crosslinked hydrogel co-loading SDF-1α and Mg2+(XPMS hydrogel) provides a novel strategy to repair bone defects.Keywords:hydrogel;BMSCs recruitment;sequential drug release;osteogenic differentiation;bone regeneration
研究领域:
生物材料
·
组织工程
·
再生医学
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DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2011
·
IF 3.723
Jiangdong Dai,Jianming Pan,Longcheng Xu,Xiuxiu Li,Zhiping Zhou,Rongxian Zhang,Yongsheng Yan
In the work, we reported an effective method for the preparation of molecularly imprinted nanoparticles with superparamagnetic susceptibility through atom transfer radical emulsion polymerization (ATREP), and then as-prepared magnetic molecularly imprinted nanoparticles (MMINs) were evaluated as adsorbents for selective recognition of tetracycline (TC) molecules from aqueous medium. The resulting nanoparticles were characterized by FT-IR, TGA, VSM, SEM and TEM. The results demonstrated MMINs with a narrow diameter distribution were cross-linked with modified Fe 3 O 4 particles, composed of imprinted layer and exhibited good magnetic sensitivity, magnetic and thermal stability. Batch rebinding studies were carried out to determine the specific adsorption equilibrium, kinetics, and selective recognition. The estimated adsorption capacity of MMINs towards TC by the Langmuir isotherm model was 12.10 mg g −1 at 298 K, which was 6.33 times higher than that of magnetic non-molecularly imprinted nanoparticles (MNINs). The kinetic property of MMINs was well-described by the pseudo-second-order rate equation. The results of selective recognition experiments demonstrated outstanding affinity and selectivity towards TC over competitive antibiotics. The reusability of MMINs showed no obviously deterioration at least five repeated cycles in performance. In addition, the MMINs prepared were successfully applied to the extraction of TC from the spiked pork sample.
研究领域:
材料科学
·
环境科学
·
分析化学
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DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2016
·
IF 3.014
Dong Zhang,Xuanxuan Ma,Qi Zhang,Yanru Xie,Qiang Shi,Qiangru Wang,Wenjun Wang
Zn x Al 2 O 4 :Cr 3+ (0.8 ≤ x ≤ 4) phosphors with spinel structure were prepared by using sol-gel method. The structure, morphology and photoluminescence properties were analyzed by using X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), electron paramagnetic resonance (EPR) and photoluminescence (PL). The spinel structure of ZnAl 2 O 4 was formed for all samples, and hexagonal structure of ZnO appeared in the powders with x ≥ 1.1. The results of XRD, SEM and TEM showed that the crystallinity of Zn x Al 2 O 4 :Cr 3+ phosphors was improved with increasing the value of x . The PL spectra showed a series of sharp emission peaks ranging from 650 nm to 730 nm assigned to spin-forbidden 2 E g → 4 A 2 g transition of Cr 3+ ions in spinel lattices. The most intense emission was observed in Zn 1.2 Al 2 O 4 :Cr 3+ powders, and the results of EPR showed that this enhancement resulted from the best dispersity of Cr 3+ ions in Zn x Al 2 O 4 lattices.
研究领域:
材料科学
·
无机化学
·
固体物理
·
发光材料
·
纳米材料
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DOI
高影响因子
OPTICAL MATERIALS
·
2016
·
IF 2.183
Pande Zhang,Benxue Jiang,Jintai Fan,Xiaojian Mao,Long Zhang
Cr and Nd co-doped laser ceramics, as the potential gain materials in inertial confinement fusion (ICF), have been widely investigated. And the study on valence states of chromium ions is important. The effects of sintering additives and annealing atmosphere on the valence state of chromium were studied in detail, and the results shown that the Cr valence states were demonstrated to be Cr 2+ and Cr 3+ ions in HIP-sintered Cr(0.2 at.%), Nd(0.8 at.%): LuAG laser ceramics. And the intensity of the near-infrared absorption band caused by Cr 2+ ions was attenuated with the decreasing SiO 2 concentration and increasing MgO amount. The near-infrared absorption could be eliminated by annealing in air. And the transformation of valence states of Cr ions in the Cr,Nd:LuAG ceramics were also confirmed by electron paramagnetic resonance and X-ray photoelectron spectroscopy.
研究领域:
材料科学
·
光学工程
·
物理学
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DOI
高影响因子
Advanced Physics Research
·
2023
·Vol. 2
·期 11
·2300006
·
IF 0
Shun Lan,Fanqi Meng,Bingbing Yang,Yue Wang,Yiqian Liu,Lvye Dou,Letao Yang,Hao Pan,Xi Kong,Jing Ma,Yang Shen,Ce-Wen Nan,Yuan-Hua Lin
Electrostatic energy storage capacitors based on dielectrics have attracted much attention due to their wide applications in advanced electrical technology and electronic devices. Generally, high energy density is achieved at a high electric field, while conduction loss becomes nonnegligible, which harms practical applications. Here distinctly suppressed leakage current in BaZr 0.5 Ti 0.5 O 3 -based films by entropy engineering is realized. With increased entropy, the leakage current density decreases by two orders of magnitude at the electric field of 3 MV cm −1 , leading to a markedly improved energy efficiency of 87% at an ultrahigh breakdown strength of 8 MV cm −1 in high-entropy films. Thereby, a high energy density of 51.9 J cm −3 is achieved. This work demonstrates the effectiveness of entropy engineering in improving the breakdown strength of dielectric films and shows great potential in enhancing the energy storage performance of capacitors.
研究领域:
材料科学
·
电气工程
·
凝聚态物理
·
纳米技术
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DOI
危险品化学品经营许可证（带存储）