Journal of Materiomics
·
2026
·
IF 9.6
Xing Fan,Chuanyin Xiong,Yadong Su,Xianglin Ji,Yongkang Zhang
This study proposes an innovative preparation strategy for composite phase change materials (PCMs) based on flexible polymer networks, addressing the urgent market demand for AI-compatible electronic skins. By encapsulating PCMs within a PVDF polymer framework and leveraging layered manufacturing and integrated assembly techniques, flexible composite PCMs that synergize thermal management with intelligent sensing have been successfully developed. The resulting material demonstrates dual-function superiority: 1) Thermal Performance: A single-layer packaging efficiency of 96.7% is achieved at a minimal thickness of 0.25 mm, with the photothermal/electrothermal conversion efficiency reaching 82.3% while retaining 92% of the initial enthalpy after 500 cycles. 2) Mechanical Robustness: Liquid metal films exhibit tensile strength up to 150 MPa, with hot-pressed samples demonstrating exceptional brittleness resistance. 3) Smart Integration: Real-time multimodal force sensing is achieved through force–thermal coupling effects, which were validated in photothermal/electrothermal experiments with precise temperature regulation via interruption effects. This breakthrough establishes a new paradigm for next-generation electronic skins, simultaneously fulfilling energy conversion efficiency and tactile responsiveness requirements. These findings hold significant promise for applications in medical robotics, industrial inspection, and consumer electronics, paving the way for adaptive human–machine interfaces.
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2015
·
IF 4.642
Lei Qin,Jianan Zhang,Hongye Cheng,Lifang Chen,Zhiwen Qi,Weikang Yuan
Deodorizer distillate as a byproduct of vegetable oil refining is an important source of natural vitamin E. Simple and green extraction can be employed to recover vitamin E from deodorizer distillate, and its performance strongly relies on the solvent used in the process. In order to screen an imidazolium-based ionic liquid (IL) as entrainer, a methodology integrating theoretical and experimental evaluations was applied. ILs composed of 47 types of anions were first investigated by COSMO-RS to figure out the most promising one, and the effect of the alkyl chain on the imidazolium ring was addressed by experiments. The IL [C6MIm]Ac was finally determined as the most promising solvent with the selectivity of 108.23 and the partition coefficient of 8.182 for α-tocopherol. The liquid–liquid equilibrium data and the extraction result for corn oil deodorizer distillate indicate its superior performance for the extraction process dealing with a low concentration of vitamin E.
研究领域:
分离科学
·
绿色化学
·
生物化工
·
离子液体
·
天然产物提取
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.1
Jiahao Teng,Yihang Xu,Yulun Wu,Xuqing Wang,Xinwei Wang,Jiye Wang,Hong Song,Yingsheng He,Yazhou Qin
With the rise of electronic cigarettes ( E -cigarettes), certain illegal additives have gradually emerged in these products, posing significant health risks to humans. Consequently, there is an urgent need for rapid and highly sensitive detection of illegal additives in E -cigarettes. This study combines deep learning algorithms with Surface-Enhanced Raman Spectroscopy (SERS) to achieve the sequential detection following phase separation of the illegal additive nicotine and the new psychoactive substance etomidate. First, by utilizing prepared gold nanoparticles as an enhancement substrate, we accomplished highly sensitive detection of nicotine and etomidate standards. Additionally, through density functional theory calculations, we established the attribution of the characteristic peaks of both substances, providing a basis for their qualitative differentiation. Additionally, by developing a liquid-liquid extraction method, we successfully isolated nicotine and etomidate from e-cigarettes, achieving highly sensitive SERS detection with lowest detectable concentrations of 0.18 ng/mL and 1 μg/mL, respectively. Finally, by integrating one-dimensional convolutional neural network (1D-CNN), we attained a classification accuracy of 94.0% for real samples. Therefore, this strategy may provide a reference for the detection of illegal substances in the future.
✓ 已验证
产品关联
DOI
高影响因子
ULTRASONICS
·
2026
·
IF 4.8
Huiyu Huang,Jia Yin,Quanquan Yang,Shuo Zhang,Zhong Chen,Yuyang Lin,Qiang Tang,Xiaomin Qi,Songfei Su,Jinyan Chen,Shengling Qu,Pengzhan Liu,Junhui Hu
The capability for high-precision detection and identification of sweat metabolites is of great importance for personalized healthcare, disease monitoring, and early management of health risks. In this study, we develop an acoustics-catalyzed e-tongue (ACET), which compactly integrates an ultrasonic actuation unit with a biosensor unit based on the oxygen reduction reaction mechanism, enabling substantially enhanced sweat metabolite detection and identification compared with the standalone biosensor unit. Owing to the synergistic effects of ultrasonic excitation and the accompanying acoustofluidic effects, the steady-state response of the biosensor is experimentally improved by up to one order of magnitude (10 × ), while the limit of detection is reduced by as much as 80% through ultrasonic catalysis. Moreover, a unique metabolite identification strategy is proposed for the ACET, achieving a 100% success rate for metabolite-type identification of NaCl and KCl under high-concentration conditions with strong ultrasonic excitation. Beyond its outstanding performance in sweat metabolite detection and identification, which is highly attractive for healthcare management, the ACET provides a robust and versatile platform for physically enhancing electrochemical reactions through ultrasonic catalysis, holding strong potential for a broad range of biosensing applications.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MACROMOLECULES
·
2026
·
IF 5.7
Qiyuan Wang,Xiaohui Kang,Shihui Li,Zhen Zhang,Dongmei Cui
Kinetic resolution polymerization (KRP) of nonpolar conjugated dienes remains a significant challenge because of their flexible coordination modes and subtle reactivity differences between isomers. Herein, we report that by fine-tuning ligand steric environments and metal centers, the KRP of naturally occurring (E,Z)-β-ocimene (E/Z-Oc) was successfully realized by using catalysts 1 and 5 to afford a stereoregular E-homopolymer while simultaneously isolating a Z-isomer with high purity (>95.5%). Moreover, complex 1 enabled to polymerize Z-Oc in highly isotactic trans-1,4 selectivity in moderate activity and rapidly polymerized E-Oc in an atactic 1,2-regularity-enriched mode, which may provide the block copolymer of poly(E-Oc)-b-poly(Z-Oc) by stepwise loading of Z-Oc followed by E-Oc. Using complex 2, the block copolymer of poly(E-Oc)-b-poly(Z-Oc) was obtained in one pot. Real-time 1H nuclear magnetic resonance kinetic studies revealed that E-Oc polymerized significantly faster than Z-Oc, depending on the ligand structure. Density functional theory calculations further indicated that the isomer-dependent regio- and stereoselectivity originated from chain-end and geometric site control mechanisms. This work demonstrated that rare-earth metal catalysts provide a powerful platform for KRP of complex terpene-derived dienes, offering a sustainable strategy for both isomer separation and precise polymer synthesis.
✓ 已验证
DOI
高影响因子
DALTON TRANSACTIONS
·
2023
·Vol. 52
·期 42
·15484-15488
·
IF 4
Xiangyu Zhang,Yunlei Chen,Yongfang Sun,Fei Wang,Xiao-Dong Wen,Tian-Nan Ye
Wide application of novel materials often requires low-cost preparation methods. In this study, we present a simplified and facile preparation method for the [Ca24Al28O64]4+(e−)4 electride material (C12A7:e−). Successful preparation of the C12A7:e− electride was confirmed by XRD patterns and magnetic behavior analysis. The concentration of electrons in the prepared C12A7:e− powder was calculated to be approximately 2.23 × 1021 cm−3, as evaluated by iodometry and TPD. DFT calculations provided insight into the unique electronic structure of C12A7:e−. Additionally, the substitution of the Ca reductant with CaH2 led to a reduction in the solid-state reaction temperature from 1100 to 950 °C, which can be attributed to thermodynamic effects such as a reduction in ΔG°.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomedicine-Nanotechnology Biology and Medicine
·
2023
·
IF 5.4
Chunjing Guo,Min Cao,Ningning Diao,Wenxin Wang,Hongxu Geng,Yanguo Su,Tianying Sun,Xinyue Lu,Ming Kong,Daquan Chen
Diabetic nephropathy (DN) is an important complication of diabetes and is the main cause of end-stage renal disease. The pathogenesis of DN is complex, including glucose and lipid metabolism disorder , inflammation, and so on. Novel hybrid micelles loaded Puerarin (Pue) based on Angelica sinensis polysaccharides (ASP) and Astragalus polysaccharide (APS) were fabricated with pH-responsive ASP-hydrazone-ibuprofen (BF) materials (ASP-HZ-BF, SHB) and sialic acid (SA) modified APS-hydrazone-ibuprofen materials (SA/APS-HZ-BF, SPHB) by thin-film dispersion method. The SA in hybrid micelles can specifically bind to the E -selectin receptor which is highly expressed in inflammatory vascular endothelial cells . The loaded Pue could be accurately delivered to the inflammatory site of the kidney in response to the low pH microenvironment . Overall, this study provides a promising strategy for developing hybrid micelles based on natural polysaccharides for the treatment of diabetic nephropathy by inhibiting renal inflammatory reactions, and antioxidant stress.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Materials Technologies
·
2022
·Vol. 7
·期 12
·2200371
·
IF 8.856
MingYang Yang,Guangyou Liu,Zheng Zeng,Shuhao Zhang,Jie Liu,Zong Qin,Zhihe Chen,Bo-Ru Yang
Human–machine interaction will be revolutionarily different in the future Internet of Things (IoT) environments. Many displays will be adopted onto electronic devices to enhance human–device communication, even under a very bright sunlight ambience. Thus, power consumption and sunlight visibility are important attributes for this application. Electrophoretic displays (EPDs) have the inherent advantages of ultra-low power consumption and high sunlight visibility, which are perfectly suitable for IoT applications. The low power consumption resulted from the balance of viscosity, gravity, and other complicated forces involved in the electrophoretic dispersion. This force balance is generally termed “bistability,” meaning the particle-packing can be stable without external power at black and white image states. However, good bistability implies a slow image updating rate, significantly degrades users’ experience. In this work, a 3D network structure that undergoes disruption and reorganization with the particles’ movement is utilized in the electrophoretic ink dispersion. Dynamic viscosity modulation enables the bistable and fast-response dual-working modes. The newly developed design can increase the response speed of EPDs by a factor of 2.38, simultaneously maintaining the bistability. The electronic ink with this reversible network provides a promising solution for the future video-rate e-paper displays.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2022
·
IF 6.51
Jinfeng He,Shuqian Yu,Ziyi Ma,Haotian Sun,Qinghua Yang,Zhiwei Liu,Xuan Wang,Xiaoyu Zhang,Longgang Wang
Gold nanoparticles are a kind of good photothermal agents. However, gold nanoparticle photothermal agents have low photothermal conversion efficiency and low tumor inhibiting ability. To overcome these problems, polymyxin E (PE) biomineralized and doxorubicin-loaded gold nanoflowers (DOX-SH@AuNFs) nanodrug was synthesized by the green synthesis method using the biological antimicrobial peptide PE as a stabilizer and grower of crystal seed, and doxorubicin-thiol (DOX-SH) was further loaded on the gold nanoparticles through the Au-S bond. The final DOX-SH@AuNFs displayed a wide absorption band in the UV–Vis spectra, and their photothermal conversion efficiency was 33.9%. Furthermore, the inhibition rate of DOX-SH@AuNFs on A549 cells was as high as 80.1% under the irradiation of near-infrared light at 808 nm. The tumor inhibition rate of DOX-SH@AuNFs was as high as 87.81% in vivo experiments. The high tumor suppression rate was attributed to the high photothermal conversion ability of DOX-SH@AuNFs and the delivery of doxorubicin. Taken together, the method of preparing DOX-SH@AuNFs provides a new idea for the treatment of cancer by photothermal therapy and chemotherapy synergistic system.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF BIOLOGICAL CHEMISTRY
·
2021
·Vol. 298
·期 2
·
IF 5.157
Binxiang Cai,Chunyan Liao,Danxue He,Jingmeng Chen,Jiahuai Han,Jiaying Lu,Kaiqi Qin,Wenxu Liang,Xiaoling Wu,Zuguo Liu,Yalin Wu
The breakdown of all-trans-retinal (atRAL) clearance is closely associated with photoreceptor cell death in dry age-related macular degeneration (AMD) and autosomal recessive Stargardt's disease (STGD1), but its mechanisms remain elusive. Here, we demonstrate that activation of gasdermin E (GSDME) but not gasdermin D promotes atRAL-induced photoreceptor damage by activating pyroptosis and aggravating apoptosis through a mitochondria-mediated caspase-3-dependent signaling pathway. Activation of c-Jun N-terminal kinase was identified as one of the major causes of mitochondrial membrane rupture in atRAL-loaded photoreceptor cells, resulting in the release of cytochrome c from mitochondria to the cytosol, where it stimulated caspase-3 activation required for cleavage of GSDME. Aggregation of the N-terminal fragment of GSDME in the mitochondria revealed that GSDME was likely to penetrate mitochondrial membranes in photoreceptor cells after atRAL exposure. ABC (subfamily A, member 4) and all-trans-retinol dehydrogenase 8 are two key proteins responsible for clearing atRAL in the retina. Abca4−/−Rdh8−/− mice exhibit serious defects in atRAL clearance upon light exposure and serve as an acute model for dry AMD and STGD1. We found that N-terminal fragment of GSDME was distinctly localized in the photoreceptor outer nuclear layer of light-exposed Abca4−/−Rdh8−/− mice. Of note, degeneration and caspase-3 activation in photoreceptors were significantly alleviated in Abca4−/−Rdh8−/−Gsdme−/− mice after exposure to light. The results of this study indicate that GSDME is a common causative factor of photoreceptor pyroptosis and apoptosis arising from atRAL overload, suggesting that repressing GSDME may represent a potential treatment of photoreceptor atrophy in dry AMD and STGD1.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
International Journal of Nanomedicine
·
2016
·
IF 4.32
Yuling Liu,Yingqi Xu,Minghui Wu,Lijiao Fan,Chengwei He,Jian-Bo Wan,Peng Li,Meiwan Chen,Hui Li
Mitoxantrone (MIT) is a chemotherapeutic agent with promising anticancer efficacy. In this study, Pluronic F68-vitamine E succinate (F68-VES) amphiphilic polymer micelles were developed for delivering MIT and enhancing its anticancer activity. MIT-loaded F68–VES (F68–VES/MIT) micelles were prepared via the solvent evaporation method with self-assembly under aqueous conditions. F68–VES/MIT micelles were found to be of optimal particle size with the narrow size distribution. Transmission electron microscopy images of F68–VES/MIT micelles showed homogeneous spherical shapes and smooth surfaces. F68–VES micelles had a low critical micelle concentration value of 3.311 mg/L, as well as high encapsulation efficiency and drug loading. Moreover, F68–VES/MIT micelles were stable in the presence of fetal bovine serum for 24 hours and maintained sustained drug release in vitro. Remarkably, the half maximal inhibitory concentration (IC50) value of F68–VES/MIT micelles was lower than that of free MIT in both MDA-MB-231 and MCF-7 cells (two human breast cancer cell lines). In addition, compared with free MIT, there was an increased trend of apoptosis and cellular uptake of F68–VES/MIT micelles in MDA-MB-231 cells. Taken together, these results indicated that F68–VES polymer micelles were able to effectively deliver MIT and largely improve its potency in cancer therapy.
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2023
·Vol. 107
·期 2
·956-967
·
IF 3.9
Sai-Dong Xue,Yu-Jing Yang,De-Long Zhang
Growth of Er 3+ -doped 100-nm thick LiNbO 3 (LN) films on Z-cut LiTaO 3 (LT) single-crystal by e -beam evaporation and in-situ anneal at 600–800°C was studied. Crystalline phase, crystallographic orientation, Er 3+ spectroscopic properties, constituent element valence states, defects, Er 3+ concentration and stoichiometry of the films were characterized. The results show that the films are in LN single-crystal state and orient along with c crystallographic axis. Constituent elements Li, O and Er are present in their respective single valence states Li + , O 2− , Er 3+ , while the Nb is in two valence states Nb 5+ and Nb 4+ . The films have Li 2 O-contents around congruent point. Antisite(Nb Li 4+ ) is the major defect. Its concentration decreases, while Li 2 O-content, crystallinity degree, and fluorescence intensity increase with increased growth temperature. The presence of Er 3+ in the grown films is in the form of LN crystalline phase. Its concentration is considerably lower than that in initial target material because of lower e -beam evaporation efficiency of heavy Er 3+ .
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）