Journal of Environmental Chemical Engineering
·
2022
·
IF 7.968
Xinyu Yao,Xianbo Hou,Guocheng Qi,Rubing Zhang
Super-wetting fibrous membranes have been widely researched for the separation of oil-water mixtures and light oil-water emulsions. However, reusable oil-water separation membranes for heavy oil with high viscosity and high density have proved to be extremely challenging. Herein, superhydrophobic, flexible, and foldable polyimide (PI) nanofiber membranes for heavy oil separation were prepared by using electrospinning method combined with surface modification to build a stable nano-scale roughness on the fiber surface. The results demonstrated that the fibrous membranes modified by fumed silica and 1H, 1H, 2H, 2H-perfluorooctyl trichlorosilane(PFTS) not only had excellent mechanical robustness, but also achieved both ultra-high oil-water selectivity and separation performance. The as-prepared PI fibrous membranes showed the ultra-high gravity-driven light/oil-water emulsion separation flux of 3904.7 L m −2 h −1 and 22474.7 L m −2 h −1 with and without emulsifier stabilization, and the flux of heavy oil can reached 271.36 L m −2 h −1 under 25KPa. The mechanically robust and reusable PI fibrous membranes with high efficient oil-water emulsion and heavy oil separation performance exhibit great potential for practical applications for oily wastewater and oil spill treatment.
研究领域:
材料科学
·
环境工程
·
化学工程
·
纳米技术
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DOI
高影响因子
Journal of Cleaner Production
·
2020
·
IF 7.246
Pan Zhang,Yuanyuan Cui,Kaiqiang Zhang,Sainan Wu,Dongchu Chen,Yanfeng Gao
The inherent leakage of molten paraffin during the solid-liquid transition and the immature state of industrial technology currently limit its practical applications for temperature regulation in smart energy-saving buildings. Here, a 1H, 1H, 2H, 2H-perfluorodecyltriethoxysilane modification of diatomite with an oleophobic surface was used as a supporting material of molten paraffin for enhancing thermal storage capacity of paraffin/diatomite composite. The results show that an optimal encapsulation ratio of the paraffin/diatomite composite is up to 84.5%, with excellent thermal reliability after a 50-cycle of melting and freezing. The simulation test demonstrates that the indoor temperature is reduced by 5.3 °C in a phase change material room with the paraffin/diatomite composite window as compared to that of an ordinary simulation room. Diatomite with oleophobic surface as a molten paraffin supporting material is effective in improving the thermal storage capacity of the composite. The paraffin/diatomite composite is a potential material with the applications in energy-saving buildings.
研究领域:
材料科学
·
能源工程
·
建筑技术
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高影响因子
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
·
2023
·Vol. 238
·期 3
·471-473
·
IF 0.3
Li Liu,Huan-Mei Guo,Li-Li Liu,Xin-Ru Qian
C 27 H 26 N 9 O 10 Pr, monoclinic, P 2 1 / c , a = 13.2280(12) Å, b = 5.5628(5) Å, c = 41.140(3) Å, β = 105.109(2)°, V = 2922.6(4) Å 3 , Z = 4, R gt
( F ) = 0.0426, w R ref
( F
2 ) = 0.0803, T = 298.15 K.
研究领域:
化学
·
材料科学
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DOI
高影响因子
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
·
2024
·
IF 3.1
Fangqi Cao,Shuchen Yu,Xiujuan Chen,Lu Xiao,Tingting Qiu,Xiru Wang,Daiwen Zhang,Xiaoliang Yuan,Ping Shi
Synthetic cannabinoids (SCs) are an evolving class of new psychoactive substances (NPS) with structurally various compounds that are increasing over the past few years. Therefore, they are initially hard to identify because of the lack of analytical information. Moreover, there is little to no information regarding the pharmacology of these compounds despite human abuse. In the present study, gas chromatography-mass spectrometry (GC-MS), ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF MS), and nuclear magnetic resonance (NMR) spectroscopy were used to identify the structure of three compounds obtained from seized materials. The pharmacological properties of these compounds were evaluated by subsequent behavioral testing, including von Frey and cold allodynia tests. The results indicated that these compounds were determined to be 2-(1 H -indazole-3-carboxamido)-3,3-dimethylbutanoate (MDMB-INACA), N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1 H -indazole-3-carboxamide (ADB-INACA), and N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-hexyl-1 H -indazole-3-carboxamide (ADB-HINACA) via GC-MS, UPLC-Q-TOF MS and NMR analysis, and they can attenuate mechanical and cold allodynia induced by paclitaxel in rats with peripheral neuropathy. Compared with MDMB-INACA and ADB-HINACA, ADB-INACA showed better analgesic effects on paclitaxel-induced peripheral neuropathy (PIPN) in rats, and its effect was similar to that of the positive drug N′-(1-hexyl-2-oxoindolin-3-ylidene) benzohydrazide (MDA-19).
研究领域:
药理学
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毒理学
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分析化学
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DOI
PubMed
高影响因子
MAGNETIC RESONANCE IN CHEMISTRY
·
2025
·
IF 1.4
Xiaoyan Zhang,Yaozuo Yuan,Yang Liu,Caiyu Zhang,Huiwen Deng,Songzi Jiang,Li Gan,Hui Fu,Xiaojuan Deng,Baoning Su,Jing Zhang,Fan Wu,Xingxiang Lv,Tong Liu,Yang Liu,Taijun Hang,Haiwei Shi
The research team established a quantitative 1 H NMR method to determine the relative ethoxy content ( EO %) in ethylcellulose using a CDCl 3 /TFA-d solvent mixture. High-field NMR spectroscopy enabled direct measurement without the use of internal or external calibrants by integrating the methyl proton signals (δ 1.15 ppm) and the methylene/methine proton signals (δ 2.5–5.5 ppm), and using their equivalent 1 H numbers and corresponding mass fractions for calculations. The EO % was calculated as: EO % = 315 r 486 − 614 r $$ \frac{315r}{486-614r} $$ × 100, where r = I A I A + I B $$ \frac{I_A}{I_A+{I}_B} $$ (I A methyl 1 Hs integral; Iᴃ methylene/methine 1 Hs integral). Round robin multi-laboratory validation testing showed that the qNMR results deviated by less than 3% from the certificate of analysis (COA) values (44%–51%). The COA values, derived using the pharmacopeial gas chromatography-flame ionization detection (GC-FID) method, may be affected by factors related to incomplete derivatization and the volatility and instability of the product (iodoethane) and the inert internal reference standard (n-octane). Therefore, the qNMR method with its operational simplicity, reduced chemical hazards, and robust performance presents an alternative for quality control of pharmaceutical-grade ethylcellulose.
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DOI
PubMed
高影响因子
TALANTA
·
2017
·
IF 4.162
Ting Li,Yong Liao,Xiaoyan Jiang,Di Mu,Xiandeng Hou,Chunchun Zhang,Pengchi Deng
The chemical shifts of several important endogenous phosphorus compounds under different pH conditions were explored, including adenosine-5′-triphosphate, adenosine-5′-diphosphate, adenosine-5′-monophosphate, phosphorylcholine and phosphorylethanolamine. Their 31 P NMR and 1 H NMR chemical shifts were all pH-sensitive in the similar pH range. Two dimensional (2D) 1 H– 31 P NMR spectra were found helpful to identify these endogenous phosphorus markers in biological samples from rather complicated NMR spectra. Herein, for the first time, a pH sensor based on 2D 1 H– 31 P NMR was established and applied to biological samples analysis with pH values determined in good agreement with those by potentiometric method . Apart from being simple, green, rapid and less sample-consuming, information concerning both the endogenous phosphorus markers and pH status could be attained in a single NMR run, which demonstrated the great potential of this method in rare sample analysis and even disease diagnosis.
研究领域:
生物化学
·
医学诊断
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Hongtu Qiu,Kexin Qu,Hua Zhang,Jong-Bang Eun
In this study, 1 H nuclear magnetic resonance was used to track the evolution of oxidation products of different multi-element oleogels (DMEOs) during temperature-accelerated oxidative degradation. The nutritional properties of the DMEOs were also indirectly explored. Oleogels prepared using sitosterol/lecithin oleogelator showed higher nutritional properties than those prepared using carnauba wax or ethyl cellulose oleogelators. Only a small amount of primary oxidation product hydroxide, (Z,E)-conjugated dienic systems, and (E,E)-conjugated dienic systems were produced from all oleogels upon accelerated oxidation. Furthermore, no 1 H signal peaks of secondary oxidation products, such as aldehydes or ketones, were detected. However, very small amounts of primary alcohols (−CH 2 OH–), secondary alcohols (−CHOH–), and epoxides were identified. Moreover, resveratrol loading and surfactant addition effectively stabilized the internal structure and unsaturated fatty acid acyl content of the oleogels.
研究领域:
食品科学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2020
·
IF 5.065
Shengbo Zhu,Wei Li,Bingyang Lu,Weixing Chen,Wenzhi Zhang,Xiaoling Niu,Xinbing Chen,Zhongwei An
Two series of terminal epoxy compounds, PmOBC (m = 1, 2, 3, 4) and P1OBEn (n = 6, 8, 10, 12), were synthesized for investigating the effect of epoxidation on mesomorphic and thermal stabilities. Molecular polarization and configuration obtained by DFT calculations can provide theoretical perspective. In addition, thermal stability is evaluated by the combination of DSC , TGA , and 1 H NMR. Compared with the corresponding alkenyl compounds, epoxidation reduces the molecular dipole moment and increase the molecular steric effect , which is not conducive to the formation of LC phases, but the reduced intramolecular energy may be helpful to improve thermal stability. Therefore, these terminal epoxy LCs are very promising for application in display devices requiring extremely high-temperature environments.
研究领域:
材料科学
·
物理化学
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产品关联
DOI
高影响因子
Membranes
·
2022
·Vol. 12
·期 12
·1188
·
IF 4.562
Yu-Ping Zhang,Ning Wang,De-Liang Chen,Yuan Chen,Meng-Jun Chen,Xin-Xin Chen
Water/oil separation from their mixture and emulsion has been a prominent topic in fundamental research and in practical applications. In this work, a smart superhydrophobic membrane (SHP) was obtained by dipping an off-the-shelf laboratory filter paper in an ethanol suspension of trichloro (1H,1H,2H,2H-tridecafluoro-n-octyl) silane, tetraethyl orthosilicate, and titanium dioxide nanoparticles with different dimensions of 20 and 100 nm. The selection of membrane substrates was optimized including different quantitative and quantitative filter papers with different filtration velocity (slow, intermediate, and fast). The as-prepared SHP was demonstrated to be superhydrophobic and photosensitive, which was used in the separation of carbon tetrachloride and water from their mixture and emulsion. Moreover, orderly aligned micropores were formed for the modified superhydrophobic filter papers by using nanosecond laser. Unidirectional penetration was obtained for the UV-irradiated paper with a bored pore in the range of 50–500 μm in the systems of air/water and water/oil. This study may promote the understanding of unidirectional transportation of liquid droplet and facilitate the design of interfacial materials with Janus-type wettability.Keywords:superhydrophobic filter paper;Janus membranes;dip coating;emulation separation;nanosecond laser
研究领域:
材料科学
·
环境工程
·
化学工程
·
纳米技术
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产品关联
DOI
PubMed
高影响因子
BIOMACROMOLECULES
·
2026
·
IF 5.9
Deshuo Wang,Wenze Xiao,Susu Yan,Zipeng Wang,Junnan Ma,Shoujing Sun,Jianjiang He,Jingjiang Sun,Qingfu Wang,Yanan Li,Wei Zhao
Dual-modal 19F/1H MRI probes often suffer from hydrophobic aggregation caused by high fluorine content, limiting their solubility and imaging performance. Herein, a water-soluble dual-modal probe (PFCP-Gd) was developed by grafting fluorinated phosphocholine zwitterions and Gd3+ chelates onto a UV-responsive polymer via RAFT polymerization and ring-opening reactions. The design enables UV-triggered paramagnetic relaxation enhancement (PRE) modulation, allowing for activatable 19F/1H MRI contrast. Upon UV irradiation, PFCP-Gd exhibited a significantly enhanced 19F signal with a T2 relaxation time of 23 ms and a signal-to-noise ratio of 11.34 at 12 mM 19F. The probe also showed good biocompatibility and an efficient cellular uptake. This work provides a strategy for constructing water-soluble, activatable fluorinated MRI probes for dual-mode imaging.
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DOI
PubMed
高影响因子
Small
·
2026
·
IF 11.8
Xinxin Yang,Qingbin Zeng,Jiawei Zhu,Xiuchao Zhao,Zhen Wang,Zhongyu Xiao,Yanling Feng,Yaping Yuan,Chenlu Yuan,Haidong Li,Sa Xiao,Louis-S. Bouchard,Xin Zhou,Qianni Guo
Metal-organic framework (MOF) films synergize molecular-scale porosity with conformal surface chemistry on polymer substrates. We report a spectrally selective coating in which a ZIF-8 film, seeded by a Zn(II)-polydopamine (Zn-PDA) interlayer on polytetrafluoroethylene (PTFE), enables hyperpolarized 1 2 9 Xe MRI detection of the polymer surface, while conventional 1 H MRI delineates anatomy. The coating produces a film-bound 1 2 9 Xe resonance at 82.0 ppm in both water and fetal bovine serum. After 60 min, the resonance position remained unchanged, with signal-to-noise ratios decreasing by only 14.9% and 17.2%, respectively. Selective excitation yields coating-specific positive contrast on the 1 2 9 Xe channel; correspondingly, 1 H MRI reveals a distinct surface appearance likely due to altered local proton density and magnetic susceptibility. In phantoms, 1 2 9 Xe and 1 H images were co-registered with a center-point offset of 0.34 mm; in a flow simulator, the offset was 0.26 mm. A rat airway experiment confirmed in vivo spectral selectivity with a film-bound resonance near 92 ppm, co-localizing with 1 2 9 Xe ventilation and 1 H anatomical references. While demonstrated here using coated PTFE segments and direct xenon bubbling, these results provide a robust proof of concept for MOF-coated polymers as spectrally selective 1 2 9 Xe MRI labels, warranting future physiological translation.
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Microorganisms
·
2026
·Vol. 14
·期 6
·1220
·
IF 4.7
Chen Yao,Zhi-Cheng Li,Ruo-Hang Li,Peng-Xiang Liu,Hong-Yun Yang,Hang Liu,Bo Ding,Heng Wang,He-Ping Li,Yue-Ying Wang,Sheng-Li Ming,Li-Jun Shi,Meng-Di Wang
The 3,4-dihydropyrimidin-2(1H)-one (DHPM) scaffold possesses diverse biological activities and chemical tunability, allowing structural modifications to modulate antiviral, anticancer, and anti-inflammatory effects. In this study, a series of DHPM derivatives with varied substituents were designed and synthesized, and their structures were characterized by1H NMR,13C NMR and HRMS. Their antiviral activities against pseudorabies virus (PRV) and vesicular stomatitis virus (VSV) were evaluated. In vitro assays revealed that several compounds exhibited significant antiviral effects, with4bf(SI = 243.08 against PRV),4ce(SI = 196.4 against VSV), and4be(SI = 124.2 against PRV; SI = 181.1 against VSV) showing the most potent activity. Further studies demonstrated effective inhibition of viral titers, and Western blot and qRT-PCR analyses confirmed downregulation of viral proteins and related genes. Cytotoxicity tests indicated that4bf,4ce, and4behad CC50values of 270.0, 147.1, and 190.9 μg/mL, respectively, suggesting favorable safety profiles. In vivo experiments showed that4bf, without affecting normal growth, alleviated PRV-induced pulmonary inflammation and tissue damage, and improved survival in mice. Taken together, DHPM-based compounds demonstrate promising potential as candidate antiviral agents, warranting further development.
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