TALANTA
·
2024
·
IF 5.6
Yingjiang Wang,Mingjing Li,Lingbo Qu,Lanlan Yu,Zhaohui Li
Laccase is well-known for its eco-friendly applications in environmental remediation and biotechnology, but its high cost and low stability have limited its practical use. Therefore, there is an urgent need to develop efficient laccase mimetics. In this study, a novel laccase-mimicking nanozyme (MBI-Cu) was successfully synthesized using 2-methylbenzimidazole (MBI) coordinated with Cu 2+ by mimicking the copper active site and electron transfer pathway of natural laccase. MBI-Cu nanozyme exhibited excellent catalytic activity and higher stability than laccase, and was utilized to oxidize a series of phenolic compounds. Environmental pollutant aminophenol isomers were found to display different color in solution when catalytically oxidized by MBI-Cu, which provided a simple and feasible method to identify them by the naked eye. Based on the distinct absorption spectra of the oxidized aminophenol isomers, a colorimetric method for quantitatively detecting o-AP, m-AP, and p-AP was established, with detection limits of 0.06 μM, 0.27 μM, and 0.18 μM, respectively. Furthermore, by integrating MBI-Cu-based cotton pad colorimetric strips with smartphone and utilizing color recognition software to identify and analyze the RGB values of the images, a portable colorimetric sensing platform was designed for rapid detection of aminophenol isomers without the need for any analytical instrument. This work provides an effective reference for the design of laccase nanozymes and holds significant potential for applications in the field of environmental pollutant monitoring.
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高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Minggui Gong,Jiajie Su,Ying Chen,Kaixin Zheng,Lijie Yuan,Fangyuan Qin,Huawei Niu,Yong Ye
Heavy metal ions tend to accumulate through the food chain and may cause many serious diseases. As an antioxidant, cysteine (Cys) plays a crucial role in regulating redox homeostasis. In addition, Cys is also widely used in the food industry. Therefore, the development of a convenient, sensitive, and practical tool for detecting Cys is of great significance for investigating the physiological and pathological functions of Cys induced by heavy metal ions. In this paper, a fluorescent probe NYVB with aggregation-induced emission (AIE) activities has been designed and synthesized, which featured good advantages in Cys detection, including favorable selectivity, desirable sensitivity, wide linear range, and low detection limit. The prepared solid-state sensor enabled the ratiometric visual detection of Cys. Probe NYVB has been successfully implemented for testing Cys in real food samples and serum samples with satisfactory recoveries. In addition, probe NYVB has been successfully employed for detecting endogenous and exogenous Cys in SKOV3 cells. More excitingly, probe NYVB has also been used to track the detection of Cys in H 2 O 2 , Hg 2+ , or Cu 2+ -induced redox imbalance. Overall, probe NYVB will open up a new avenue for studying Cys in the amelioration of heavy metal toxicity and has practical applications.
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JOURNAL OF MEDICINAL CHEMISTRY
·
2024
·
IF 6.8
Chao Zhao,Wanlu Sun,Yanyan Zhu,Xiaoyan Huang,Ye Sun,Hai-Yan Wang,Yi Pan,Yi Liu
Photodynamic therapy (PDT) is an innovative and promising method for treating tumors that has attracted significant interest but still faces several challenges, such as a lack of selectivity, deep penetration of light, and efficient ROS generation. To address these challenges, we optimized and synthesized a series of photosensitizers and successfully developed a heavy-atom-free near-infrared FUCL photosensitizer NFh-NMe-2. This photosensitizer can generate singlet oxygen (1O2) and induce cellular apoptosis under 808 nm light. For the safe ablation of microtumors in vivo, an activatable FUCL photosensitizer NFh-NTR was developed based on the overexpression of nitroreductase (NTR). NFh-NTR could be activated by NTR, leading to the release of the photosensitizer NFh-NMe-2, restoring the fluorescence signal, and effectively killing tumor cells under 808 nm light irradiation. This work opens new possibilities in the chemical design of an FUCL photosensitizer for cancer treatment.
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高影响因子
ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Nuanfei Zhu,Xiangheng Niu,Zheng Liang,Yixing Tian,Hongyi Yin,Ze Qiao,Zhen Zhang
Enzymatic cascade reactions with high activity and specificity in living cells always benefit from multicompartmentalized organelles that provide separately confined spaces for enzymes, avoiding their mutual interference to ensure the high-efficiency operation of necessary vital movements. Inspired by this, we designed a 3D spherical microreactor (Au@H-APF@Pt) with biomimetic cascade catalysis for glucose detection. First, ultrasmall gold nanoparticles were immobilized in situ on the internal cavities of hollow 3-aminophenol formaldehyde resin (H-APF) nanospheres, along with glucose oxidase activity. Then, platinum nanoparticles (PtNPs) with peroxide-like activity were reduced surrounding the outer layer of the H-APF nanospheres. Similar to the cell structure, different metal sites in this bifunctional microreactor operated independently, bringing higher catalytic activity and selectivity and thus being synergistically capable of a cascade reaction to catalyze the substrate for glucose detection. This cell-mimicking microreactor (Au@H-APF@Pt) was successfully applied in glucose colorimetric detection, showing a 1.9-fold activity enhancement compared to direct mixing (Au/Pt). The observed low catalytic activity was attributed to the extended time for transferring hydrogen peroxide (H2O2) from Au NPs to the solution and then to PtNPs. Integrating a smartphone APP, a real-time, visual, and Au@H-APF@Pt-based hydrogel sensor for glucose detection was also proposed. Satisfactory results highlight that this cell-mimicking microreactor offers a very successful strategy to improve the efficiency of cascade catalysis systems in biosensing.
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高影响因子
Journal of Energy Storage
·
2024
·
IF 8.9
Dongdong Zhang,Weijun Ma,Kaixi Li
The deliberate integration of monodisperse carbon nanospheres (MCS) with unique interior morphology and mesoporous plays a crucial role in supercapacitor , but its synthetic methodology is still difficult. Here, a layer-by-layer coating coupled nano-confined pyrolysis strategy is developed to manipulating internal morphology and mesoporous in MCS. This synthesis features the employment of polymethyl methacrylate nanospheres (PMMA) as hard template and in-situ activator, allowing the aggregation of phenolic resin and silica on PMMA, and forcing CO 2 and H 2 O generated by PMMA pyrolysis encapsulated in shell. The internal morphology can be achieved by tuning PMMA amount, and the mesoporous can be controlled by optimizing PMMA pyrolysis kinetics. The optimized hollow carbon bowl-like spheres (HCB) presents a higher capacitance of 140.5 F g −1 than carbon spheres of 10.0 F g −1 and hollow carbon spheres of 99.9 F g −1 at 0.1 A g −1 , confirming that the internal morphology can effectively increase capacitance. Moreover, the reinforced mesoporous in HCB induce capacitances increasing from 111.9 to 117.3 and 140.5 F g −1 , confirming that small mesopore is the main host for organic ions. The HCB-based supercapacitor presents a higher energy density of 30.5 Wh kg −1 at power density 337.5 W kg −1 in TEABF 4 and 61.6 Wh kg −1 at 175 W kg −1 in MeEt 3 NBF 4 , and excellent cycling stability. This work validates the feasibility of enhancing capacitance by designing internal morphology and mesoporous in MCS.
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高影响因子
Journal of the Taiwan Institute of Chemical Engineers
·
2025
·
IF 6.3
Xinyang He,Ying Tian,Weiwei Lu,Fangfen Jing,Mingzhu Jin,Jiahui Zhu,Qi Fong,Rongtai Yu
Background The widespread presence of antibiotics in aquatic environments poses severe ecological risks due to inadequate removal in conventional wastewater treatment. This study investigates morphology-controlled concave polymer nanospheres for simultaneous tetracycline (TC) degradation and photocatalytic H 2 O 2 production. Methods Synthesis of aminophenol-formaldehyde resins (APF) using 3-aminophenol (3-AP), ammonia water, and formaldehyde. Through precise acetone-mediated etching, three concave resin catalysts with distinct concavities (70–78 nm) and wall thicknesses (47–54 nm) were synthesized. Significant findings Systematic characterization revealed that increased wall thickness enhanced visible-light absorption (up to 700 nm), while higher concavity improved light reflection efficiency. The catalyst synthesized with 38 mL acetone demonstrated optimal H 2 O 2 yield (168.5 mg g⁻¹), whereas the maximum TC degradation efficiency (106.57 % at 180 min) was achieved using the 32 mL acetone-etched catalyst with the deepest concavity. Mechanistic studies identified synergistic effects between light scattering geometry and charge carrier dynamics, where concave structures facilitated multi-directional photon utilization while thickened walls suppressed electron-hole recombination. This work provides new insights into morphology engineering for dual-functional photocatalytic systems in environmental remediation.
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高影响因子
POLYMER DEGRADATION AND STABILITY
·
2025
·
IF 7.4
Yanlu Sun,Shuo Fan,Xiulin Li,Xubin Wang,Dequn Wu,Xueli Wang,Jianyong Yu,Ruchao Yuan,Faxue Li
The limited carbon layer formation during combustion causes severe melt droplet formation and excessive heat release in polyamide 6 (PA6) filaments, hindering their application in textiles. In this work, phosphorus-containing transition metal complexes PAPH-M (M = Co, Ni, Zn) were synthesized by combining 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) with high oxidation state phosphorus and transition metal elements to enhance the carbonization effect of flame retardants in the PA6 matrix during combustion. By incorporating 10 wt% PAPH-Co into the PA6 matrix (PA6/PAPH-Co), a UL94 V-0 rating was achieved with no melt droplet. The peak of heat release rate (p-HRR) and total heat release (THR) of PA6/PAPH-Co decreased to 623 kW·m -2 and 56.8 MJ·m -2 , exhibiting reductions of 41.5% and 36.0%, respectively, compared to pure PA6. The exceptional flame retardancy, heat suppression and anti-dripping behaviors of PA6/PAPH-M composites were attributed to the quenching effect and barrier effect. Additionally, PA6/PAPH-M composites demonstrated exceptional UV-blocking capabilities, with ultraviolet protection factor (UPF) values of around 1900 compared to 3 for pure PA6. Melt-spun PA6/PAPH-Co filaments self-extinguished within 2 s in vertical burning tests and maintained sufficient mechanical strength for textile processing, confirming their sustained comprehensive performance post-spinning.
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ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Kexin Jin,Xueai Li,Yuning Shi,Chunsheng Wang,Wanchun Guo,Kesong Tian,Haiyan Wang
Discrete nanocrystals, curvature, and core-shell structures synergistically trigger intense polarization for amorphous carbon to achieve broadband microwave absorption. However, the distinguishable effects of the defects in amorphous carbon on microwave dissipation remain challenging, and the identification of critical factors for enhancing dipole polarization requires further clarification. Herein, collective engineering of defects and concavities in thin-shelled hollow amorphous carbon with discrete graphite nanocrystals is proposed to identify the effective pathways of dielectric loss for broadband response and strong microwave absorption. The appropriate conductive net and charge imbalance is the primary essential factor to enhance dielectric loss capacity; then defects in thin-shelled amorphous carbon, induced intense dipole polarization, are more critical to achieve broadband response than concavity and geometry effect. As a result, the thin-shelled hollow amorphous carbon with more defects demonstrates a more remarkable broadband response capability with an effective absorption bandwidth (reflection loss, RL≤ −10 dB) of 8.08 GHz and efficient dissipation of −80.70 dB. This work not only provides carbon microwave absorbing materials with broadband response, meanwhile strong microwave absorption but also proposes critical insights into the polarization loss mechanisms associated with defects in amorphous carbon.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2024
·
IF 2.7
Zhijiao Chen,Cong Peng,Shichao Li,Zhanjun Wu,Tao sun
Phthalonitrile monomer containing oxazine ring (BPS-Ph) was synthesized using bisphenol-S, aniline, paraformaldehyde, and 4-nitrophthalonitrile via a two-step method. The differential scanning calorimetry (DSC) data of the curing process of BPS-Ph monomer indicates that the peak polymerization temperature of the cyan group is about 250°C and that confirms the promoting effect of oxazine ring on the curing reaction of phthalonitrile. The rheological data of E51/DDS containing BPS-Ph indicates that the BPS-Ph monomer also has promoting effect on the curing process. The activation energy was studied via the iso-conversional method principle. The activation energy corresponding to the E51/DDS crosslinking reaction is 75.79 and 60.54 kJ mol −1 , respectively, for pure E51/DDS and E51/DDS/BPS-Ph. Moreover, the activation energy of the crosslinking of phthalhydrazine is 74.1 kJ mol −1 which is rather lower than that in pure BPS-Ph, and that implies the synergistically catalytic effect of the oxazine ring and the amine. The addition of BPS-Ph monomer significantly improves the thermal behaviors of the thermoset. The char yield in N 2 atmosphere increased from 15.6% to 53.9% when adding 30% BPS-Ph to the E51/DDS. Moreover, the peak weight loss temperature decreased from 407 to 385°C. The phase separation size of poly-BPS-Ph in E51/DDS is about tens to hundreds nanometers according to the atomic force microscopy (AFM) phase diagram. It is indicated that incorporation of phthalonitrile monomer containing oxazine ring into epoxy/amine system is an applicable and effective way to promote the thermal behavior of the thermoset.
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Small Structures
·
2024
·
IF 13.9
Xinrui Chen,Xing Han,Caixia Zhang,Xue Ou,Xiaoli Liu,Junhua Zhang,Wei Liu,Arthur J. Ragauskas,Xueping Song,Zhanying Zhang
Light-emitting diodes (LEDs) are widely used in lighting and display applications. Carbon quantum dots (CQDs), which have high biocompatibility, high resistance to photobleaching, and full-spectrum luminescence, have inherent advantages as fluorescent materials for LED devices. Herein, multicolor CQDs are prepared by a new reagent engineering strategy due to the difference of effective conjugate length and the surface electron-withdrawing groups of CQDs. White CQDs are realized by mixing blue, green, and red CQDs proportionally. Then, the aggregation-caused quenching phenomenon of CQDs is suppressed through the hydrogen-bonding network of cellulose nanofibrils (CNFs). Multicolor fluorescent films are prepared from CQDs and CNFs by simple mixing and casting methods. Finally, thin-film encapsulation based on the photosensitive resin ABPE-10 coating can be realized and rapidly assembles into fluorescent films with different light-emitting colors into LED devices, leading to have superior thermal performance compared with conventional LEDs. White LEDs have excellent white-light illumination performance, with Commission Internationale de L’Eclairage color coordinates of (0.33, 0.37), a correlated color temperature of 5688 K, and a color rendering index of 86. This strategy provides a convenient and scalable pathway for low-cost, environmentally friendly, and high-performance CQDs-based LEDs.
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高影响因子
ChemistrySelect
·
2024
·Vol. 9
·期 33
·e202402724
·
IF 1.9
M. Z. Jin,J. Li,D. Song,F. F. Jing,W. W. Lu,X. Y. He,T. Wang,R. T. Yu
Graphical A dendritic nano-polymer was synthesized and used as a photocatalyst for H 2 O 2 production and Tetracycline/ Rhodamine B degradation under a 36 W incandescent bulb. The yield of H 2 O 2 is 8.4 mg g −1 h −1 , and the photocatalytic degradation rates of Rh B and TC can reach 93.9 % and 72.92 %, respectively. A process for photocatalytically synthesizing hydrogen peroxide while simultaneously degrading organic pollutants is of interest. In this study, a dendritic nanopolymer was synthesized and utilized as a photocatalyst for the production of hydrogen peroxide, which was then used in tandem with the degradation of Tetracycline (TC) and Rhodamine B (Rh B) organic pollutants under a 36 W incandescent bulb. The yield of H 2 O 2 was measured at 8.4 mg g −1 h −1 , with photocatalytic degradation rates of 93.90 % for Rh B and 72.92 % for TC. The degradation kinetics of TC and Rh B by the dendritic polymer were found to follow pseudo-first-order kinetics, and a higher affinity for degradation was observed for Rh B. The photocatalytic degradation mechanism of TC in a Fenton-like system was attributed to an oxidation system involving hydrogen peroxide and ferrous ions.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Xue Zhang,Yamin Yu,Kaixin Du,Wenwei Han,Jie Xue,Shanshan Li,Shangyou Lv,Jianye Fu,Xin Wang,Meng Qiu
The global pandemic of coronavirus disease 2019 (COVID-19) highlights the shortcomings of the current testing paradigm for viral disease diagnostics. Though the Polymerase Chain Reaction (PCR) technique is currently used for nucleic acid detection in liquid samples, its application in airborne virus has not yet been developed, due to low viral load in the air, lack of efficient capture probe and supporting equipment. Herein, we developed an ultrasensitive biosensing nanoplatform for airborne virus detection. The extraction and concentration of nucleic acid from test samples has been accomplished by novel spike silica nanoparticles (SSNPs)-based nucleic acid capture probe with high spike length to nanoparticle diameter ratio and appropriate surface potential. When integrated with air sampler and Quantitative Real-Time PCR (qPCR) equipment, nucleic acid enrichment can be achieved significantly. Our results demonstrated a successful detection of the virus in the air with the limit of detection (LoD) of 500 copies/L, which greatly surpasses the LoD of 1 × 10 6 copies/L. This detection method effectively addresses the obstacle posed by the low abundance of pathogens in the environment and could be applied for the detection of pathogens in air or water, aiming to achieve the goal of disease prevention and control prior to its onset.
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危险品化学品经营许可证（带存储）