JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2024
·
IF 4
Dingkui Xiang,Yue Ma,Jiaxu Yao,Minjie Zhao,Haijiao Li,Eric Marchioni,Li Zhou
Shiitake mushroom ( Lentinus edodes ), as a prestigious edible mushroom and one of the most famous medicinal mushrooms, is cultivated in several regions of China. In this study, the total lipids of shiitake mushroom from different origins were characterized by ultra-high-performance liquid chromatography-quadrupole-Exactive-Orbitrap MS/MS (UHPLC-QE Orbitrap/MS/MS). 20 lipid classes and 174 lipid molecular species were determined by non-targeted lipodomics analysis. The multivariate analysis showed that 19 lipids were screened as potential markers for distinguishing shiitake mushroom of different origins, for instance, phosphatidic acid (18:2/18:2) (PA 18:2/18:2) and phosphatidylglycerol (16:0/18:2) (PG 16:0/18:2). And the Partial Least Squares-Discriminant Analysis (PLS-DA) model reconstructed was used to distinguish shiitake mushroom from different regions with a success rate of 100 %. This work comprehensively provided the lipid information of shiitake mushroom and demonstrated the great potential of lipidomics for tracing the authenticity of shiitake mushrooms from different origins.
研究领域:
食品科学
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分析化学
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生物化学
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DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 54
·43528-43536
·
IF 3.84
Suhang Xun,Wenshuai Zhu,Dan Zheng,Hongping Li,Wei Jiang,Ming Zhang,Yuejiao Qin,Zhen Zhao,Huaming Li
High activity oxidation of sulfur compounds to sulfones in extraction coupled with catalytic oxidative desulfurization (ECODS) system catalyzed by supported ionic liquid [Bmim]FeCl4/Am TiO2 was reported. The catalysts were analyzed by thermogravimetric (TG) analysis, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS). It was found that [Bmim]FeCl4 and Am TiO2 had a synergistic effect on the desulfurization system. Effects of calcination temperature of the catalyst and various reaction conditions on the catalytic activity of desulfurization were investigated. Moreover, GC-MS analyses were employed to prove the process of the desulfurization. As a solid catalyst, the supported ionic liquid could be separated from the reaction easily. The recycling tests showed that the desulfurization efficiency remained 100% after reusing it for 25 times. Therefore, the ECODS system has excellent reusability and is promising for industrial applications for catalytic oxidative desulfurization.
研究领域:
化学工程
·
催化材料科学
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DOI
高影响因子
mAbs
·
2018
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IF 5.165
De-zhi Li,Bing-nan Han,Rui Wei,Gui-yang Yao,Zhizhen Chen,Jie Liu,Terence C.W. Poon,Wu Su,Zhongyu Zhu,Dimiter S. Dimitrov,Qi Zhao
Site-specific conjugation of small molecules to antibody molecules is a promising strategy for generation of antibody-drug conjugates. In this report, we describe the successful synthesis of a novel bifunctional molecule, 6-(azidomethyl)-2-pyridinecarboxyaldehyde (6-AM-2-PCA), which was used for conjugation of small molecules to peptides and antibodies. We demonstrated that 6-AM-2-PCA selectively reacted with N-terminal amino groups of peptides and antibodies. In addition, the azide group of 6-AM-2-PCA enabled copper-free click chemistry coupling with dibenzocyclooctyne-containing reagents. Bifunctional 6-AM-2-PCA mediated site-specific conjugation without requiring genetic engineering of peptides or antibodies. A key advantage of 6-AM-2-PCA as a conjugation reagent is its ability to modify proteins in a single step under physiological conditions that are sufficiently moderate to retain protein function. Therefore, this new click chemistry-based method could be a useful complement to other conjugation methods.
研究领域:
化学
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生物化学
·
药学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2025
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IF 4.7
Ousseini Seidina Ousseini,Bo Peng,Zhuang Miao,Kai Cheng,Mandella Ali,Jingwei Li,Jixiang He,Seybou Yacouba Zakariyaou
This study presents the synthesis and evaluation of a novel nanocomposite using dispersion polymerization of Acrylamide (AM), Acrylic Acid (AA), 2-acrylamido-2-methyl propane sulfonic acid (AMPS), and N, N’-methylenebisacrylamide (MBA) grafted onto the surface of modified nano-SiO 2 (M-NS). The modification, achieved using γ-Methacryloyloxypropyltrimethoxysilane (KH570), enhances hydrophobicity and stability. Comprehensive characterization techniques, including ultraviolet-visible spectroscopy (UV-Vis), Fourier-transform infrared (FTIR), laser particle size analysis, and zeta potential measurements were employed to confirm the structural integrity and functionalization of the nanocomposite. Emphasis was placed on examining swelling, viscosity, and dispersion stability under various temperature, salinity, and water conditions to determine its effectiveness under high-temperature and high salinity environments typical of oil reservoirs. The results revealed significant enhancements in swelling behavior and dispersion stability, with high resistance to thermal degradation and salinity-induced aggregation. The nanocomposite demonstrates superior swelling behavior, viscosity retention, and thermal stability under high-temperature (70°C) and high-salinity (up to 20g/L NaCl) conditions, outperforming traditional grafted polymers. Results demonstrated that swelling ratios improve by 45% with 2wt% M-NS, and viscosity degradation is significantly reduced over 20 days of aging. Ionic effects, analyzed show enhanced resistance to divalent ions (Mg 2+ and Ca 2+ ), critical for harsh reservoirs environments. These findings suggest superior conformance control, compliance, and thermal stability, which were further improved with the rise of modified nano-SiO 2 positioning this nanocomposite as a promising option for chemical-enhanced oil recovery applications, addressing in permeability heterogeneity and salinity-induced aggregation.
研究领域:
材料科学
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石油工程
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化学工程
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2017
·
IF 6.216
Zhang Yimeng,Chu Wenhai,Xu Ting,Yin Daqiang,Xu Bin,Li Pan,An Na
Hydrogen peroxide with and without activation by ultraviolet irradiation (UV/H 2 O 2 and H 2 O 2 , respectively) has been investigated to degrade emerging contaminants in drinking water. The antibiotic chloramphenicol (CAP) and its analogues (thiamphenicol and florfenicol), referred to collectively as CAPs, can produce a range of disinfection by-products (DBPs) during chlorination or chloramination (chlor(am)ination). The impact of unactivated and activated H 2 O 2 pre-oxidation on the formation of nitrogenous and carbonaceous DBPs from the chlor(am)ination of CAP model precursors was investigated. A theoretical estimated toxicity evaluation was also carried out based on the DBPs that formed. H 2 O 2 pretreatment alone did not affect organic carbon and nitrogen concentrations, but significantly reduced the formation of trichloromethane (TCM) during chlorination and trichloronitromethane (TCNM) during chloramination, and enhanced dichloroacetonitrile (DCAN) yields during chloramination. These significant changes in DBP yields caused by H 2 O 2 pre-oxidation are attributable to the transformation of the three CAPs into more reactive precursor structures. The three CAPs did not form DCAN and TCNM during chlorination, regardless of whether H 2 O 2 pre-oxidation was used. However, UV/H 2 O 2 pretreatment resulted in the unexpected formation of TCNM during chlorination. Furthermore, UV/H 2 O 2 pre-oxidation increased the formation of DCAN and TCNM, whereas it had little effect on TCM formation during chloramination. A preliminary estimated toxicity evaluation demonstrated that UV/H 2 O 2 pre-oxidation at low doses, followed by chlorination, resulted in the lowest estimated toxicity from a range of DBPs. Conversely, the estimated toxicity evaluation showed that unactivated H 2 O 2 (high dose) was preferable to UV activated H 2 O 2 for overall control of these investigated DBPs during chloramination.
研究领域:
环境科学
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公共卫生学
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2026
·
IF 2.6
Yuzuo Liu,Jiawei Li,Bin Li,Zhigang Hu,Haoyu Lv,Ying Wang
In this work, nitrogen-doped carbon quantum dots (N-CQDs) were successfully synthesized via a microwave-assisted route using citric acid and o-phenylenediamine as precursors. A deep eutectic solvent was subsequently constructed using choline chloride as the hydrogen bond acceptor and glycerol/acrylamide as hydrogen bond donors. The N-CQDs were introduced as functional nanofillers, and a P(AM-Gly-ChCl)/N-CQDs composite hydrogel was obtained through photopolymerization. The chemical composition and microstructure of the composite hydrogel were systematically characterized by SEM, XPS, and FTIR, verifying the effective incorporation of N-CQDs into the hydrogel network. The effect of N-CQDs content on the mechanical, sensing, and adsorption properties of the hydrogel was elucidated. With increasing N-CQDs content, both tensile fracture stress and tear energy were substantially improved. The composite hydrogel exhibited an enhanced pressure-sensitive response, with a relative capacitance change of 137.0% achieved at an applied load of 1 N for the hydrogel containing 0.3 wt% N-CQDs. In addition, incorporation of N-CQDs endowed the hydrogel with effective Fe3+ adsorption capability and pronounced fluorescence quenching behavior, highlighting its potential for multifunctional applications that integrate pressure sensing and metal-ion detection.
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2025
·
IF 2.5
Jie Song,Yingnan Zhou,Lijun Chen,Zhiwen Yuan,Yuhua Niu,Xi Li,Liangxian Huang
This study employed β-cyclodextrin (β-CD) for the hydrophilic modification of iron tetraoxide (Fe3O4) magnetic materials. Subsequently, potassium humate (KHA) and carboxymethyl cellulose (CMC) were used as raw materials. A β-CD@Fe3O4/KHA/CMC/AM/MAH hydrogel with magnetic properties which can be easily recycled was synthesized for the slow release of glyphosate (GLY). FTIR, XRD, TG and VSM analyses demonstrated that the hydrogel possesses good thermal stability and magnetic properties with a saturation magnetization strength of 29.77 emu g−1. The equilibrium solubility of the hydrogel in pH = 7.4 and pH = 8.5 buffer was 24.58 g g−1 and 25.83 g g−1, respectively. The maximum release of GLY was recorded at 63.31% and 67.78%, with the drug release behavior under different loading gels following the Fickian diffusion mechanism. A pot planting experiment indicated that the water content of plants treated with the β-CD@Fe3O4/KHA/CMC/AM/MAH drug-loaded gel decreased by 51.69%. Additionally, soluble protein levels decreased to 2.69 mg g−1, chlorophyll content decreased to 0.486 mg g−1, SOD levels decreased to 43.81 U g−1, and MDA increased to 4.02 μmol g−1, effectively inhibiting the growth of grass and providing a theoretical basis for achieving slow drug release.
研究领域:
材料科学
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高分子科学
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环境科学
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农业化学
·
纳米技术
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2026
·
IF 5.4
Ming Zhou,Zhihui Meng,Chenyiting Li,Xiao Guo,Ronghua Yue,Yuxiang Liu,Jianhong Zhou
Polymer microspheres are widely used in petroleum, electronics, biomedicine, and other industrial fields. This article aims to overcome the problems of poor thermal stability and insufficient mechanical strength of conventional polymer microspheres in high-temperature and high-salinity reservoirs. A composite nanosphere with controllable size and excellent temperature and salt resistance was synthesized by introducing modified nano-SiO 2 to construct an organic-inorganic composite system. The composite nanosphere is crucial for the effectiveness of profile control, water plugging, and oil displacement under harsh reservoir conditions. In this study, amphoteric SiO 2 /P(AM-AMPS-DMDAAC) composite microsphere with small size and regular shape were successfully prepared by reverse phase microemulsion polymerization. A mixed solution of acrylamide (AM), 2-acrylamide-2-methylpropanesulfonic acid (AMPS), diallyldimethylammonium chloride (DMDAAC), KH-570 modified nano-SiO 2 , and methylenebisacrylamide (MBA) was used as the aqueous phase, with Span-80 and Tween-80 as composite emulsifiers. The microsphere exhibits excellent comprehensive physicochemical properties, with a controllable median particle size of approximately 30 nm. Its thermal decomposition temperature increases from 201 °C to 241 °C, and has good viscoelasticity and pseudoplastic characteristics. These properties enable it to effectively cope with harsh reservoir conditions such as high temperature and low permeability. Through oil displacement experiments, the microspheres achieved an average plugging rate of 85.9 % in low-permeability cores and increased the oil recovery by 16.79 %. These indicate that the composite microspheres, as an efficient profile control and water plugging agent, have broad application prospects for enhanced oil recovery in low-permeability reservoirs.
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DOI
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 10
·6114-6122
·
IF 3.108
Bingzhi Liu,Huaili Zheng,Xiangrui Deng,Bincheng Xu,Yongjun Sun,Yongzhi Liu,Jianjun Liang
A template assembly method was introduced to obtain a cationic hydrophobic micro-block structure based amphiphilic electrolyte poly(acrylamide-co-2-methacryloxyethyltrimethyl ammonium chloride) P(AM-DMC) in this work, thereby increasing charge density and enhancing charge neutralization ability at the same charge density. The alteration of copolymerization or homo-polymerization was evaluated by the changes in reactivity ratios, so as to unravel the mechanism of template assembly. The micro-blocks generated by the new distribution of sequences were demonstrated by 1H nuclear magnetic resonance spectroscopy (1H NMR) and differential thermal-thermogravimetric analysis (DSC-TGA). Two negative controls were employed in sludge dewatering experiments to further evaluate the advanced properties of the template-assembled polymer. The results further verified that the positive effect of template assembly on flocculation performance of the polymer was achieved mainly through two ways: improving charge density and generating the micro-block structure. It can be concluded that the introduction of template assembly into polymerization can improve the performance of the polymer.
研究领域:
环境科学
·
高分子化学
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产品关联
DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2023
·
IF 8.1
Jinrui Zhu,Li Zhou,Minjie Zhao,Fang Wei,Haiyan Fu,Eric Marchioni
Coffee is popular worldwide and its consumption is increasing in recent years. Although mass spectrometry-based lipidomics approaches have been prevalent, their application in studies related to detailed information and dynamic changes in lipid composition during coffee bean roasting is still limited. The aim of this study was to investigate the dynamic changes in coffee bean lipids during the roasting process. The lipid classes and lipid molecular species in coffee beans were characterized by lipidomic analysis combined with chemometrics. A total of 12 lipid classes and 105 lipid molecular species were identified and quantified. Triacylglycerols (TAG) was the most abundant lipid class in both green beans and roasted beans. The content of phosphatidylethanolamine (PE) and lysophosphatidylethanolamine (LPE) in green beans was obviously higher than that in roasted beans. Other phospholipids , such as phosphatidylinositol (PI), lysophosphatidylinositol (LPI), phosphatidylcholine (PC), lysophophatidylcholine (LPC) and phosphatidic acid (PA), showed a tendency to increase at the beginning of roasting, then decreased gradually. Several differential lipid molecule species, for instance, PE (16:0_18:2), PC (18:2_18:2) were significantly down-regulated, and PI (18:1_18:2) was significantly up-regulated. This study provided a scientific basis for the change of coffee bean lipids during the roasting process.
研究领域:
食品科学
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分析化学
·
植物代谢
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产品关联
DOI
PubMed
高影响因子
Energy Sources Part A-Recovery Utilization and Environmental Effects
·
2022
·
IF 2.902
Shaocong Pang,Heming Zhu,Jingyuan Ma,Luo Zhao,Chaolan Yang,Yuxiu An
Viscosity reducer is used to reduce the high viscosity of drilling fluid containing bentonite as a continuous phase. However, the viscosity of drilling fluid increases and the rheology of the drilling fluid deteriorates at high temperature, causing problems such as reduction in rate of penetration and bit balling. As a core component, drilling fluids with bad rheology seriously affect the further development of drilling engineering, especially at high temperatures. Therefore, there is an urgent need for viscosity reducer suitable for high temperature. In this study, a high temperature-resistant viscosity reducer for water-based drilling fluid was prepared. The rheological parameters of drilling fluids containing 0, 0.5, 1, 1.5 wt% viscosity reducer after aging at different temperatures were evaluated. The results showed that the rheological parameters, such as apparent viscosity, yield point, plastic viscosity, and gel strength decreased within 200℃. Otherwise, filtration volume of 1.8 and 2.2 g/cm3 compound drilling fluids containing 1 wt% viscosity reducer was less than 10 ml. And its resistance to Na+ contamination reached saturation, that is, 36% NaCl solutions. The mechanism of viscosity reduction was also investigated by Fourier transform infrared and X-ray diffraction. Viscosity reducer adsorbed on the clay particles and destroyed the network structure formed by the clay particles while releasing free water.
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2016
·Vol. 133
·期 30
·
IF 1.866
Wei Gong,Meilan Li,Yunxiao Zang,Hao Xie,Bailing Liu,Hualin Chen
In order to control the impacts of blown sand in salty desert, in this article, the amphoteric emulsion, for the first time, was applied as an ecological sand-fixing material. This study started from the synthesis of the poly{vinyl acetate-dibutyl maleate-acrylamide-co-3-[ N -(2-methacroyloylethyl)- N, N -dimethylammonio]-propane sulfonate} [P(VAc-DBM-AM-DMAPS)] copolymer emulsion. Then, the structures, composition, thermal property of the emulsion were characterized by 1 H-NMR, FTIR, and DSC, respectively. The basic properties of the emulsion and salt tolerance of the latex films were measured by using viscometer, dynamic light scattering, and laser Doppler electrophoresis also. And the sand-fixing properties of the emulsion were evaluated. Finally, the influence of the emulsion on the growth of soil microbe and plants were discussed for understanding its ecological effect. The experimental results showed that the emulsion has been successfully synthesized and could be as an ecological sand-fixing material. The related reason is that, first, the emulsion could significantly improve the compressive strength and water retaining; second, the emulsion had good thermal aging, freeze-thaw stabilities and salt tolerance to withstand the changes in temperature and NaCl concentration of salty desert; third, the influence of the emulsion on the growth of plants and microbe of sand also showed a dependable ecological effect. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133 , 43715.
研究领域:
材料科学
·
环境科学
·
生态学
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DOI
高影响因子
危险品化学品经营许可证（带存储）