Defence Technology
·
2018
·
IF 0
Teng Chen,Yan Zhang,Shuang-feng Guo,Liu-ming Zhao,Wei Chen,Ga-zi Hao,Lei Xiao,Xiang Ke,Wei Jiang
A sol-gel freezing-drying method was utilized to prepare energetic nanocomposites based on 2, 4, 6, 8, 10, 12-hexanitro-2, 4, 6, 8, 10, 12-hexaazaisowurtzitane (CL-20) with 3, 3-Bis (azidomethyl) oxetane-tetrahydrofuran copolymer (BAMO-THF) as energetic gel matrix. Scanning electron microscopy (SEM), X-ray diffraction (XRD), Raman, Fourier-transform infrared spectroscopy (FT-IR) and differential thermal analyser (DTA) were utilized to characterize the structure and property of the resultant energetic nanocomposites. Compared with raw CL-20, the average particle sizes of CL-20 in CL-20/BAMO-THF energetic nanocomposites were decreased to nano scale and the morphologies of CL-20 were also changed from prismatic to spherical. FT-IR detection revealed that CL-20 particles were recrystallized in BAMO-THF gel matrix during the freezing-drying process. The thermal decomposition behaviors of the energetic nanocomposites were investigated as well. The thermolysis process of CL-20/BAMO-THF nanocomposites was enhanced and the activation energy was lower compared with that of raw CL-20, indicating that CL-20/BAMO-THF nanocomposites showed high thermolysis activity. The impact sensitivity tests indicated that CL-20/BAMO-THF energetic nanocomposites presented low sensitivity performance.
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PLoS One
·
2017
·Vol. 12
·期 5
·e0178226
·
IF 2.806
Peng-Xiao Chen,Yi-Lin Zhang,Jia-Wen Xu,Ming-Hao Yu,Jie-Hong Huang,Lei Zhao,Wen-Liang Zhou
Sodium tanshinone IIA sulfonate (STS) is a derivate of tanshinone IIA, a lipophilic compound in Salvia miltiorrhiza . This study aimed to investigate the effect of STS on ion transport in mouse tracheal epithelium and the mechanisms underlying it. Short-circuit current ( I sc ) was measured to evaluate the effect of STS on transepithelial ion transport. Intracellular Ca 2+ imaging was performed to observe intracellular Ca 2+ concentration ([Ca 2+ ] i ) changes induced by STS in primary cultured mouse tracheal epithelial cells. Results showed that the apical application of STS at mouse trachea elicited an increase of I sc , which was abrogated by atropine, an antagonist of muscarinic acetylcholine receptor (mAChR). By removing ambient Cl − or applying blockers of Ca 2+ -activated Cl − channel (CaCC), the response of STS-induced I sc was suppressed. Moreover, STS elevated the [Ca 2+ ] i in mouse tracheal epithelial cells. As a result, STS stimulated Cl − secretion in mouse tracheal epithelium via CaCC in an mAChR-dependent way. Due to the critical role of Cl − secretion in airway hydration, our findings suggested that STS may be used to ameliorate the airway dehydration symptom in cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD).
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yinan Liu,Xiangyi Tang,Fei Shen,Jiahong Zou,Yanjun Yin,Zhaojie Jiao,Xiaoshu Lv,Wenyang Fu,Yan Zou,Guangming Jiang,Hong Liu
Electrocatalytic hydrodehalogenation (ECHD) offers a promising approach for detoxification of the halogenated antibiotics via hydrogenolysis of the C-X bonds (X = F, Cl or Br). Herein we demonstrated that the commercially-available cobalt phthalocyanine (CoPc) molecules with a high-loading of −[Co-N 4 ]- moieties (Co wt%: 10.8 %) were exceptionally active for hydrogenolysis of the C-Cl bonds in florfenicol (FLO). It afforded an impressive mass activity of 6.2 g FLO h −1 g -1 Co , a low Co leaching of 0.34 μg/L and a strong tolerance to interference from impurities in water, significantly surpassing reported Co/Fe/Ni-based particle and single-site counterparts. Mechanistic studies revealed that the ECHD on CoPc underwent a direct electron transfer manner rather than the atomic hydrogen (H*)-mediated indirect way, and the ECHD efficacy was affected by both the electron and proton transfer kinetics. The single-atom Co, with its d orbitals constituting the lowest unoccupied molecular orbitals of CoPc, served as the primary active site. It facilitated both electron and proton transfer, as well as the cleavage of the C-Cl bond but not the C-F bond. In a continuous-flow cell, the CoPc/C-driven ECHD reduced the antibacterial activity of a FLO-contaminated natural lake water sample by 90.8 % with an energy consumption of 0.19 kwh g -1 FLO . This study highlighted great promise of the single-atom metal-bearing molecular catalyst toward the sustainable detoxification of halogenated antibiotics-contaminated water.
研究领域:
环境科学
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催化化学
·
抗生素污染治理
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DOI
高影响因子
DYES AND PIGMENTS
·
2020
·
IF 4.613
Beitong Zhu,Lirong Jiang,Tianhong Chen,Guang-Ming Bao,Lintao Zeng,Xichao Hu,Hou-Qun Yuan
Biogenic primary diamines are a family of critical food spoilage biomarkers. To maintain food safety, it is necessary to implement highly efficient detection methods to monitor the levels of biogenic primary diamines in edible products. In this study, we report a 7-diethylaminocoumarin derivative, CMA-Cl, as a colorimetric and fluorescence lighting-up probe for detecting critical biogenic primary diamines including cadaverine and putrescine. The CMA-Cl probe underwent a nucleophilic substitution and condensation reaction with biogenic primary diamines, generating highly emissive compounds, which displayed strong emission at 475 nm with a fluorescence quantum yield of 36.4%. The CMA-Cl probe showed colorimetric and fluorescence dual-response towards biogenic primary amines with a significant linear relationship, good selectivity, and low limit of detection (209 nM). The probe demonstrated a good recovery (97–122%) for the determination of a typical biogenic primary diamine cadaverine during the spoilage of fish. Furthermore, CMA-Cl -loaded paper was fabricated for the real-time visual detection of a typical biogenic primary diamine cadaverine in fish samples based on distinct changes in color and fluorescence.
研究领域:
食品安全
·
分析化学
·
生物化学
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DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Lanting Yang,Zhaokang Chen,Lihao Wang,Zhenwei Zhang,Ruihao Wang,Changping Guo
The high sensitivity of high explosive hexanitrohexaazaisowurtzitane (CL-20) limits its applicability, and the performance optimization brought by the synergistic effect between nanothermite and CL-20 is expected to expand its application prospects. In this study, polydopamine (PDA) was introduced to modify CL-20 (denoted as pCL-20), and a quasi-core/shell pCL-20/polytetrafluoroethylene-aluminum (pCL-20/PTFE-Al) composite was successfully prepared by ultrasonic-assisted composite method. The performance characterization results demonstrate that the composite exhibits significantly better decomposition heat release than the mixed sample, a reduction in combustion time from 408 ms to 268 ms, a more stable combustion flame, and more focused energy release. At the same time, the comparison of composite combustion with different condition variables reflects the combustion advantages of the selected proportional conditions in this study. The characteristic drop height (H 50 ) increased from 24.05 cm to 42.15 cm, the explosive percentage of friction sensitivity reduced from 100 % to 70 %, and the sensitivity of the composite sample decreased significantly when compared to the raw CL-20. It improves the combustion performance while reducing the sensitivity, thereby enhancing the application potential and providing a reference for the high-energy desensitization of energetic materials.
研究领域:
材料科学
·
爆炸物化学
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DOI
高影响因子
DALTON TRANSACTIONS
·
2014
·Vol. 43
·期 24
·9216-9225
·
IF 4.097
Qiong Wu,Tianfeng Chen,Zhao Zhang,Siyan Liao,Xiaohui Wu,Jian Wu,Wenjie Mei,Yanhua Chen,Weili Wu,Lingli Zeng,Wenjie Zheng
Two arene Ru(II) complexes coordinated by 2-(3-methoxyphenyl)imidazole[4,5-f][1,10]phenanthroline, [(η6-RC6H5)Ru(m-MOPIP)Cl]Cl (R = H, 1; R = CH3, 2), have been prepared under microwave irradiation; the crystal structure of 2 exhibits a typical “piano stool” conformation, with bond angles for N1–Ru1–Cl1 86.02 (14)° and N2–Ru1–Cl1 84.51 (14)°. The Ru–C distance for the Ru atom bound to the benzene ring is about 0.2178(8) nm, and the average Ru–N distance for Ru atom to the two chelating N atoms is about 0.2092(4) nm. The evaluation of in vitro anticancer activities revealed that these synthetic Ru(II) complexes selectively inhibited the growth of HepG2 hepatocellular carcinoma cells, with low cytotoxicity toward LO2 human normal liver cells. The results demonstrated that the complexes exhibited great selectivity between human cancer and normal cells by comparing with the ligand m-MOPIP. Furthermore, complexes 1 and 2 could bind to c-myc G4 DNA in groove binding mode in promising affinity, and the insertion of the methyl groups in the arene ligand contributed to strengthen the binding affinity. This was also confirmed by molecular docking calculation and 1H NMR analysis which showed that both 1 and 2 can bind in the loop constructed by A6–G9 and G21–A25 base pairs in c-myc G4 DNA to block the replication of c-myc oligomer. Taken together, these results suggest that arene Ru(II) complexes display application potential as small molecule inhibitors of c-myc G4 DNA.
研究领域:
无机化学
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药物化学
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癌症研究
·
DNA相互作用
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DOI
PubMed
高影响因子
ACS Nano
·
2024
·
IF 15.8
Xue Tian,Huan Liu,Bin Cao,Peng Zhang,Yanze Li,Yanchao Ou,Haonan Cui,Mengyao Xu,Bin Xu
MXenes are promising cathodes for Li–CO2 batteries owing to their high electrical conductivity and efficient CO2 activation function. However, the effects of adsorption and electronic structures of MXene on the full life cycle of Li–CO2 batteries have been rarely investigated. Here, we employ a coregulation approach to enhance the adsorption–decomposition of lithium carbonate (Li2CO3) by introducing Zn and Cl surface groups onto the Ti3C2 MXene (Zn–Ti3C2Cl2) catalyst. The incorporation of Cl surface groups enhances Li2CO3 adsorption on the MXene catalyst surface, resulting in the formation of small-sized and uniform Li2CO3. Additionally, the introduction of Zn shifts the d-band centers of titanium and promotes CO2 evolution reaction (CO2ER) activity, thereby facilitating the decomposition of discharge products. As a result, the Li–CO2 battery based on the Zn–Ti3C2Cl2 catalyst exhibits an ultralow overpotential (0.72 V) at 200 mA g–1 and stable cycling for up to 1500 h. This work validates the efficacy of promoting reversibility in Li–CO2 batteries by adjusting the adsorption-decomposition process.
研究领域:
材料科学
·
电化学
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DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Xueqing Wang,Penghao Hao,Chunyan Wang,Xue Yu,Ming Tan,Jiuqing Liu,Yang Liu,Yang Zhang
To address the growing demand for high-performance membranes in sustainable water treatment, this study developed a novel nanofiltration (NF) membrane via a mixed-monomer strategy. Interfacial polymerization was conducted on macroporous polyethersulfone (PES) supports using an aqueous phase containing piperazine (PIP) and piperazine-2-carboxylic acid (PIP-COOH), and an organic phase of trimesoyl chloride (TMC). The introduction of PIP-COOH, a carboxyl-functionalized monomer, not only increased the membrane’s surface negative charge but also moderated the interfacial reaction rate, enabling the formation of a more uniform and controllable polyamide layer. By systematically adjusting the PIP/PIP-COOH ratio and monomer concentrations, the membrane structure and separation properties were fine-tuned. Under optimal conditions (3:1 PIP/PIP-COOH, 0.4 % TMC), the membrane achieved a NaCl/Na 2 SO 4 selectivity of 19.86 and a water permeance of 10.42 L·m −2 ·h −1 ·bar −1 . Additionally, outstanding antifouling performance was demonstrated, with a total fouling ratio of just 4.62 % and a flux recovery rate of 99.07 % after hydraulic cleaning. These results highlight the potential of using functionalized monomers in mixed systems to achieve a favorable balance between permeability, selectivity, and fouling resistance. The proposed approach offers a scalable and effective pathway for designing next-generation NF membranes for sustainable water treatment and resource recovery.
研究领域:
水处理技术
·
膜科学
·
高分子化学
·
环境工程
·
可持续资源回收
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DOI
高影响因子
CHEMOSPHERE
·
2022
·
IF 8.943
Shiyu Hou,Zheng-Hong Huang,Tianle Zhu,Yiliang Tang,Ye Sun,Xiang Li,Fangxia Shen
The heat desorption of styrene from adsorbents is impracticable owing to its spontaneous polymerization under heating conditions. However, the feature also brings a potential promoting effect on styrene adsorption. Therefore, it is expected to develop the non-regenerative adsorbents with large adsorption capacity by strengthening the polymerization effect. In this work, C–Cl grafted silica gel adsorbents were prepared by introducing (Chloromethyl)dimethylchlorosilane (CMDMCS) and FeCl 2 into silica gel. The C–Cl grafted silica gel exhibited excellent styrene adsorption performance, its adsorption amounts for styrene were 4.67 times and 9 times of unmodified silica gel under dry air condition and high humidity condition (RH = 80%), respectively. In addition, the adsorption of styrene on C–Cl grafted silica gel was almost unaffected by the presence of toluene. The characterization of adsorbents after styrene adsorption indicated that the improvement of adsorption capacity of C–Cl grafted silica gel for styrene can be attributed to atom transfer radical polymerization (ATRP) of styrene molecules on modified silica gel during adsorption process .
研究领域:
环境化学
·
材料科学
·
吸附分离
·
高分子化学
·
大气污染控制
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2026
·
IF 2.6
Taihe Wang,Chengling Zou,Yu Li,Yuxin Mu,Jiale Wei,Chao Chen,Yan Zhang,Haijian Li,Jianhua Yi,Haixia Ma,Fengqi Zhao
Porphyrin metal–organic frameworks (PMOFs) with intrinsic characteristics have been extensively applied but still hold great potential as catalysts for energetic materials. Three analogous PMOFs with rod-like single-crystal structures, namely, [C48H28N4O8Cu]2·C2NH6 (PCN-74), C48H28N4O8Cu (PCN-68) and [C48H28N4O8Cu]3·C2NH6 (PCN-52), were successfully synthesized by a simple hydrothermal approach. These samples were hydrophobic with a contact angle of 141.2°. The catalytic performance of the PMOFs in promoting hexanitrohexaazaisowurtzitane (CL-20) decomposition was studied by differential scanning calorimetry (DSC). The thermal decomposition gases produced from CL-20 were further studied by thermogravimetric/Fourier-transform infrared spectroscopy/mass spectrometry (TG/FTIR/MS) with or without PMOFs. The results showed that the introduction of the catalysts decreased the thermal decomposition temperature by about 1.4 °C and reduced the activation energy of CL-20 by about 13.5 kJ mol−1. In addition, real-time detection of decomposition product fragments demonstrated that MOFs influence the decomposition pathway. These effects were evidenced by the reduced laser ignition time and changes in combustion flame images.
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高影响因子
PROPELLANTS EXPLOSIVES PYROTECHNICS
·
2022
·Vol. 48
·期 2
·e202200192
·
IF 2.134
Qi Huang,Yulan Song,Zhicheng Guo,Jinhao Zhang,Bo Jin,Ya Guo,Rufang Peng
Interface interaction has always been considered a major challenge in the field of desensitization. Co-crystal explosives can balance the properties of energetic materials, but their limited desensitization effect limits their further practical applications. Based on this, we proposed the desensitization of CL-20/HMX co-crystal by three functionalized graphene oxide (NH 2 -GO, Am-GO and M550-GO). The sensitivity results indicate that the M550-GO has the best desensitization. To further explore the reasons for the better desensitization effect of M550, molecular dynamics was used to simulate the binding energy and mechanical properties of different systems. The results showed that the electrostatic interaction between functionalized graphene oxide and CL-20/HMX co-crystal can enhance the interfacial interaction more than van der Waals force. In a word, this work provides new ideas and insights for enhancing the interface interaction of coating materials and popularizing the practical application of co-crystal explosives.
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高影响因子
ACS Applied Electronic Materials
·
2022
·
IF 4.494
Jiakun An,Gaoyu Chen,Xia Zhu,Xin Lv,Jianchun Bao,Xiangxing Xu
All-inorganic perovskite CsPbX3 (X = Cl, Br, and I) quantum dots (QDs) are emerging as attractive materials for photodetectors due to their prominent positive photoresponse. In this work, ambipolar photodetectors were constructed based on heterojunctions of CsPbX3 QDs and ZnO nanocrystals (NCs). The transition between the positive photoconductivity (PPC) and negative photoconductivity (NPC) was successfully controlled not only by the drain-source voltage (VDS) but also by the excitation wavelength and CsPbX3 crystal size. A high responsivity (R), on–off ratio (η), and detectivity (D*) were achieved for NPC (R = 1046 mA/W, η = 281, and D* = 1.65 × 1011 Jones), with PPC (R = 146 mA/W, η = 64, and D* = 1.54 × 1011 Jones) simultaneously revealed in the same device. A general mechanism combining the type-II heterojunction, the component and size-related band structure, and most critically the in-band trap states of the perovskites was established for understanding the unique ambipolar property. It exhibits application potential in developing functional photodetectors, memristors, and optical logic devices.
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高影响因子
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